Tayyaba Hasan

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. pmc Quantitative imaging of scattering changes associated with epithelial proliferation, necrosis, and fibrosis in tumors using microsampling reflectance spectroscopy
    Venkataramanan Krishnaswamy
    Dartmouth College, Thayer School of Engineering, 8000 Cummings Hall, Hanover, New Hampshire 03755, USA
    J Biomed Opt 14:014004. 2009
  2. pmc Imaging tumor variation in response to photodynamic therapy in pancreatic cancer xenograft models
    Kimberley S Samkoe
    Thayer School of Engineering, Dartmouth College, Hanover, NH, USA
    Int J Radiat Oncol Biol Phys 76:251-9. 2010
  3. ncbi request reprint Effect of tumor host microenvironment on photodynamic therapy in a rat prostate tumor model
    Bin Chen
    Thayer School of Engineering, 80000 Cummings Hall, Dartmouth College, Hanover, NH 03755, USA
    Clin Cancer Res 11:720-7. 2005
  4. pmc High vascular delivery of EGF, but low receptor binding rate is observed in AsPC-1 tumors as compared to normal pancreas
    Kimberley S Samkoe
    Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH 03755, USA
    Mol Imaging Biol 14:472-9. 2012
  5. pmc Detecting epidermal growth factor receptor tumor activity in vivo during cetuximab therapy of murine gliomas
    Summer L Gibbs-Strauss
    Thayer School of Engineering, Dartmouth College, Hanover, NH, USA
    Acad Radiol 17:7-17. 2010
  6. pmc Noninvasive measurement of aminolevulinic acid-induced protoporphyrin IX fluorescence allowing detection of murine glioma in vivo
    Summer L Gibbs-Strauss
    Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA
    J Biomed Opt 14:014007. 2009
  7. ncbi request reprint Blood flow dynamics after photodynamic therapy with verteporfin in the RIF-1 tumor
    Bin Chen
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    Radiat Res 160:452-9. 2003
  8. pmc Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo
    Scott C Davis
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Proc Natl Acad Sci U S A 110:9025-30. 2013
  9. ncbi request reprint Combining vascular and cellular targeting regimens enhances the efficacy of photodynamic therapy
    Bin Chen
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Int J Radiat Oncol Biol Phys 61:1216-26. 2005
  10. ncbi request reprint Peptide-induced inflammatory increase in vascular permeability improves photosensitizer delivery and intersubject photodynamic treatment efficacy
    Xiaodong Zhou
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Radiat Res 168:299-307. 2007

Collaborators

Detail Information

Publications23

  1. pmc Quantitative imaging of scattering changes associated with epithelial proliferation, necrosis, and fibrosis in tumors using microsampling reflectance spectroscopy
    Venkataramanan Krishnaswamy
    Dartmouth College, Thayer School of Engineering, 8000 Cummings Hall, Hanover, New Hampshire 03755, USA
    J Biomed Opt 14:014004. 2009
    ....
  2. pmc Imaging tumor variation in response to photodynamic therapy in pancreatic cancer xenograft models
    Kimberley S Samkoe
    Thayer School of Engineering, Dartmouth College, Hanover, NH, USA
    Int J Radiat Oncol Biol Phys 76:251-9. 2010
    ....
  3. ncbi request reprint Effect of tumor host microenvironment on photodynamic therapy in a rat prostate tumor model
    Bin Chen
    Thayer School of Engineering, 80000 Cummings Hall, Dartmouth College, Hanover, NH 03755, USA
    Clin Cancer Res 11:720-7. 2005
    ....
  4. pmc High vascular delivery of EGF, but low receptor binding rate is observed in AsPC-1 tumors as compared to normal pancreas
    Kimberley S Samkoe
    Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH 03755, USA
    Mol Imaging Biol 14:472-9. 2012
    ..Here, the in vivo delivery and binding kinetics of epidermal growth factor receptor (EGFR) was determined for normal pancreas and AsPC-1 orthotopic pancreatic tumors known to overexpress EGFR...
  5. pmc Detecting epidermal growth factor receptor tumor activity in vivo during cetuximab therapy of murine gliomas
    Summer L Gibbs-Strauss
    Thayer School of Engineering, Dartmouth College, Hanover, NH, USA
    Acad Radiol 17:7-17. 2010
    ....
  6. pmc Noninvasive measurement of aminolevulinic acid-induced protoporphyrin IX fluorescence allowing detection of murine glioma in vivo
    Summer L Gibbs-Strauss
    Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA
    J Biomed Opt 14:014007. 2009
    ..The red light bleaching is found to increase the ability to accurately quantify PpIX fluorescence in vivo, but decreases the specificity of detection between tumor-bearing and nontumor-bearing groups...
  7. ncbi request reprint Blood flow dynamics after photodynamic therapy with verteporfin in the RIF-1 tumor
    Bin Chen
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    Radiat Res 160:452-9. 2003
    ..These results support the hypothesis that temporal pharmacokinetic changes in the distribution of the photosensitizer between the tumor parenchyma and blood vessels can significantly alter the tumor target of PDT...
  8. pmc Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo
    Scott C Davis
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Proc Natl Acad Sci U S A 110:9025-30. 2013
    ..3 ± 0.5 nM (n = 5), consistent with values estimated in comparative invasive imaging and ex vivo studies...
  9. ncbi request reprint Combining vascular and cellular targeting regimens enhances the efficacy of photodynamic therapy
    Bin Chen
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Int J Radiat Oncol Biol Phys 61:1216-26. 2005
    ..The sequence of photosensitizer and light delivery can influence the effect of combined treatments...
  10. ncbi request reprint Peptide-induced inflammatory increase in vascular permeability improves photosensitizer delivery and intersubject photodynamic treatment efficacy
    Xiaodong Zhou
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Radiat Res 168:299-307. 2007
    ..There was also a significant reduction in the interindividual variability in with substance P plus PDT from 64% to 13%. The resulting treatment was therefore more effective and there was less variability in dose between subjects...
  11. ncbi request reprint Pretreatment photosensitizer dosimetry reduces variation in tumor response
    Xiaodong Zhou
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Int J Radiat Oncol Biol Phys 64:1211-20. 2006
    ..Conclusions: This research suggests that accurate quantification of tissue photosensitizer levels and subsequent adjustment of light dose will allow for reduced subject variation and improved treatment consistency...
  12. pmc In vivo quantification of tumor receptor binding potential with dual-reporter molecular imaging
    Kenneth M Tichauer
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Mol Imaging Biol 14:584-92. 2012
    ..A dual-reporter methodology capable of quantifying available receptor binding potential of tumors in vivo within a clinically relevant time scale is presented...
  13. ncbi request reprint Tumor vascular area correlates with photosensitizer uptake: analysis of verteporfin microvascular delivery in the Dunning rat prostate tumor
    Xiaodong Zhou
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 82:1348-57. 2006
    ..This study presents a method to systematically analyze micro-heterogeneity as well as possible methods to increase delivery and homogeneity of photosensitizer within tumor tissue...
  14. pmc Diagnostic detection of diffuse glioma tumors in vive with molecular fluorescent probe-based transmission spectroscopy
    Summer L Gibbs-Strauss
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755 8000, USA
    Med Phys 36:974-83. 2009
    ..Optical transmitted fluorescent signal may add significant benefit for clinical cases of diffuse infiltrative growth pattern glioma tumors given sufficient optimization of the signal acquisition for each patient...
  15. ncbi request reprint Protoporphyrin IX level correlates with number of mitochondria, but increase in production correlates with tumor cell size
    Summer L Gibbs
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 82:1334-41. 2006
    ..The study indicates that use of L1 in tumors with a lower innate production of PpIX with ALA alone may be the most productive approach to this combined delivery...
  16. ncbi request reprint Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic Dunning prostate tumors
    Xiaodong Zhou
    Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
    Photochem Photobiol 79:323-31. 2004
    ....
  17. ncbi request reprint Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus
    Chao Sheng
    Thayer School of Engineering, Dartmouth College, Harvard Medical School, Boston, MA, USA
    Photochem Photobiol 83:738-48. 2007
    ..This detection system and rodent model can be used for prospective dosimetry studies that focus on optimization of esophageal PDT...
  18. pmc Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure
    Sason Torosean
    Department of Physics and Astronomy, Dartmouth College, Hanover, New Hampshire, USA
    Nanomedicine 9:151-8. 2013
    ..Imaging of these parameters in vivo can lead to better individual noninvasive methods to assess drug penetration in situ...
  19. pmc Protoporphyrin IX fluorescence photobleaching increases with the use of fractionated irradiation in the esophagus
    Brian W Pogue
    Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA
    J Biomed Opt 13:034009. 2008
    ....
  20. pmc Contrast enhanced-magnetic resonance imaging as a surrogate to map verteporfin delivery in photodynamic therapy
    Kimberley S Samkoe
    Geisel School of Medicine at Dartmouth College, Department of Surgery, Lebanon, New Hampshire 03756bDartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755
    J Biomed Opt 18:120504. 2013
    ..The use of contrast-enhanced MR imaging shows promise as a method for treatment planning and photosensitizer dosimetry in human photodynamic therapy (PDT) of pancreas cancer. ..
  21. pmc System development for high frequency ultrasound-guided fluorescence quantification of skin layers
    Josiah D Gruber
    Dartmouth College, Thayer School of Engineering, 8000 Cummings Hall, Hanover, New Hampshire 03755, USA
    J Biomed Opt 15:026028. 2010
    ..Pilot in-vivo data are also presented, showing recovery of subcutaneous tumor tissue values of protoporphyrin IX in a subcutaneous U251 tumor, which has less fluorescence than the skin...
  22. pmc Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging
    Kenneth M Tichauer
    Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA
    J Biomed Opt 17:066001. 2012
    ....
  23. ncbi request reprint Photodynamic therapy with verteporfin in the radiation-induced fibrosarcoma-1 tumor causes enhanced radiation sensitivity
    Brian W Pogue
    Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire 03755, USA
    Cancer Res 63:1025-33. 2003
    ..4 +/- 1.4 days, and when PDT was given at the same time as radiation, the delay was 8.1 +/- 1.5 days. This observation indicates that the combined effect in the latter case was greater than additive (P = 0.049)...