Research Topics
Species | Maria V GrauSummaryAffiliation: Dartmouth Medical School Country: USA Publications
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Publications
Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trialMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
J Natl Cancer Inst 95:1765-71. 2003..Although these nutrients are inter-related metabolically in bone and in the normal intestine, their potential interactions in large-bowel carcinogenesis are not well understood...- Interaction of calcium supplementation and nonsteroidal anti-inflammatory drugs and the risk of colorectal adenomasMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hamsphire, USA
Cancer Epidemiol Biomarkers Prev 14:2353-8. 2005..Calcium and aspirin have both been found to be chemopreventive against colorectal neoplasia. However, the joint effect of the two agents has not been well investigated... 
Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: observational follow-up of a randomized studyMaria V Grau
Departments of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
J Natl Cancer Inst 101:267-76. 2009..We examined the persistence of the protective effect after the cessation of randomized aspirin treatment and whether it is affected by the duration and frequency of subsequent NSAID use...- Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trialMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
J Natl Cancer Inst 99:129-36. 2007..Calcium supplementation has been shown to decrease the risk of recurrence of colorectal adenomas in randomized trials. However, the duration of this protective effect after cessation of active supplementation is not known... - Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trialElizabeth L Barry
Department of Community and Family Medicine, Dartmouth Medical School, Suite 300, Evergreen Center, 46 Centerra Parkway, Lebanon, NH 03756, USA
Cancer Epidemiol Biomarkers Prev 18:2726-33. 2009..These results support the hypothesis that COX-2 plays a role in the etiology of colon cancer and may be a target for aspirin chemoprevention and warrant further investigation in other colorectal adenoma and cancer populations... - Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma preventionElizabeth L R Barry
Department of Community and Family Medicine, Dartmouth Medical School, 46 Centerra Parkway, Ste 300, Lebanon, NH 03766, USA
J Natl Cancer Inst 98:1494-500. 2006..Previous research suggests that the G315A single-nucleotide polymorphism in the ornithine decarboxylase (ODC) gene may be a genetic marker for risk of colorectal neoplasia and may also modify the association of aspirin use with risk... - Association between folate levels and CpG Island hypermethylation in normal colorectal mucosaKristin Wallace
Department of Medicine, Dartmouth Medical School, Evergreen Center, Lebanon, NH 03756, USA
Cancer Prev Res (Phila) 3:1552-64. 2010..These data have important implications regarding the safety of supplementary folate administration in healthy adults, given the hypothesis that methylation in normal mucosa may predispose to colorectal neoplasia... 
The association of lifestyle and dietary factors with the risk for serrated polyps of the colorectumKristin Wallace
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hamsphire, USA
Cancer Epidemiol Biomarkers Prev 18:2310-7. 2009..Our results suggest that several common lifestyle and dietary variables are associated with risk for serrated polyps, and some of these may differ for the right and left colorectum...- Effect of NSAIDs on the recurrence of nonmelanoma skin cancerMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03766, USA
Int J Cancer 119:682-6. 2006..There were some indications of a modest, nonsignificant reduction on the number of BCCs and SCCs with NSAID use. Our data suggest a weak and inconsistent chemopreventive effect of NSAIDs on BCC and SCC... - Risk of prostate cancer in a randomized clinical trial of calcium supplementationJohn A Baron
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
Cancer Epidemiol Biomarkers Prev 14:586-9. 2005..CONCLUSION: In this randomized controlled clinical trial, there was no increase in prostate cancer risk associated with calcium supplementation and some suggestion of a protective effect... - K-ras mutations in incident sporadic colorectal adenomasElizabeth L R Barry
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire 03766, USA
Cancer 106:1036-40. 2006..In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas that occurred during a chemoprevention trial of calcium supplementation... - Chemoprevention in gastrointestinal cancers: current statusMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03766, USA
Basic Clin Pharmacol Toxicol 98:281-7. 2006..TJ-9, polyprenoic acid and anti-aflatoxin compounds are also possible avenues that deserve future research... - Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trialHeike A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
Am J Clin Nutr 87:1945-51. 2008..The effect of supplementation with calcium alone on risk fractures in a healthy population is not clear...