Research Topics
| S T GraftonSummaryAffiliation: Dartmouth Medical School Country: USA Publications
| Collaborators
|
Detail Information
Publications
Normalizing motor-related brain activity: subthalamic nucleus stimulation in Parkinson diseaseS T Grafton
Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Neurology 66:1192-9. 2006....- Motor sequence learning with the nondominant left hand. A PET functional imaging studyScott T Grafton
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, 6162 Moore Hall, Dartmouth College, Hanover, NH 03755, USA
Exp Brain Res 146:369-78. 2002..Mirror transformation of the sequence by the right hand was associated with a marked increase in regional activity in the left motor cortex, consistent with a role for sequential transformation at this level of the motor output pathway... - Contributions of functional imaging to understanding parkinsonian symptomsScott T Grafton
Center for Cognitive Neuroscience, Dartmouth Brain Imaging Center, 6162 Moore Hall, Dartmouth College, Hanover, New Hampshire 03755 USA
Curr Opin Neurobiol 14:715-9. 2004..There is a need to understand the anatomic intersections where information is shared across these circuits... 
Ventral and dorsal stream contributions to the online control of immediate and delayed grasping: a TMS approachNichola Rice Cohen
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Neuropsychologia 47:1553-62. 2009..e. within 300 ms) due to the transient nature of TMS, which was always delivered simultaneous with movement onset. We discuss the implications of our findings in relation to interactions between the dorsal and ventral streams...- Virtual lesions of the anterior intraparietal area disrupt goal-dependent on-line adjustments of graspEugene Tunik
HB 6162 Moore Hall, Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Neurosci 8:505-11. 2005..We contend that aIPS is critical for dynamic error detection during goal-dependent reach-to-grasp action that is visually guided... - Differential role of the orbital frontal lobe in emotional versus cognitive perspective-takingCatherine A Hynes
Department of Psychological and Brain Sciences, Dartmouth College, 6162 Moore Hall, Hanover, NH 03755, USA
Neuropsychologia 44:374-83. 2006..This finding is both consistent with the lesion literature, and resolves the inconsistency of orbital frontal findings in the theory of mind literature... 
Building a motor simulation de novo: observation of dance by dancersEmily S Cross
Center for Cognitive Neuroscience and Department of Psychological and Brain Sciences, Dartmouth College, 6162 Moore Hall, Hanover, NH 03755, USA
Neuroimage 31:1257-67. 2006..Furthermore, activity in premotor and parietal areas during action simulation is enhanced by the ability to execute a learned action irrespective of stimulus familiarity or semantic label...- Action outcomes are represented in human inferior frontoparietal cortexAntonia F de C Hamilton
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Cereb Cortex 18:1160-8. 2008.... - Neural substrates of visuomotor learning based on improved feedback control and predictionScott T Grafton
The Center for Cognitive Neurosciences and Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USA
Neuroimage 39:1383-95. 2008..The results demonstrate that incremental, learning-dependent changes can be modeled on a trial-by-trial basis and neural substrates for feedforward control of novel motor programs are localized to secondary motor areas... - Cerebellar involvement in response reassignment rather than attentionAmanda Bischoff-Grethe
Center for Cognitive Neuroscience and the Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
J Neurosci 22:546-53. 2002..These results suggest the cerebellum is involved in response reassignment... - Sensitivity of the action observation network to physical and observational learningEmily S Cross
Department of Psychology, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Cereb Cortex 19:315-26. 2009.... - On-line grasp control is mediated by the contralateral hemisphereNichola J Rice
HB 6162 Moore Hall, Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
Brain Res 1175:76-84. 2007..We conclude that grasping is a lateralized process, relying exclusively on the contralateral hemisphere, and discuss the implications of these findings in relationship to models of hemispheric dominance for motor control... - BOLD coherence reveals segregated functional neural interactions when adapting to distinct torque perturbationsEugene Tunik
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire, USA
J Neurophysiol 97:2107-20. 2007..Our findings demonstrate that trial-to-trial acquisition of two distinct adaptive responses is attributed not to anatomically segregated regions, but to differential functional interactions within common sensorimotor circuits... - The anterior intraparietal sulcus mediates grasp execution, independent of requirement to update: new insights from transcranial magnetic stimulationNichola J Rice
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
J Neurosci 26:8176-82. 2006..This computation is performed for both stable and perturbed motor goals... - Goal representation in human anterior intraparietal sulcusAntonia F de C Hamilton
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
J Neurosci 26:1133-7. 2006..These regions were not sensitive to the trajectory taken by the actor's hand. This result demonstrates that the anterior intraparietal sulcus represents the goal of an observed action... - Alcohol-induced suppression of BOLD activity during goal-directed visuomotor performanceJohn Darrell Van Horn
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Neuroimage 31:1209-21. 2006.... - Transient disruption of M1 during response planning impairs subsequent offline consolidationNichola Rice Cohen
HB 6162 Moore Hall, Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Exp Brain Res 196:303-9. 2009..These results provide important new insights into the role of M1 in sequential memory consolidation and sequence response planning... - Graspable objects grab attention when the potential for action is recognizedTodd C Handy
Center for Cognitive Neuroscience, 6162 Moore Hall, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Neurosci 6:421-7. 2003..Although it is widely accepted that visual sensory gain aids perception, our results suggest that it may also have consequences for object-directed actions... - Reductions in neural activity underlie behavioral components of repetition primingGagan S Wig
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Neurosci 8:1228-33. 2005..Neural priming in early sensory regions was unaffected by left-frontal TMS--a finding that provides evidence for separable conceptual and perceptual components of priming... - Wandering minds: the default network and stimulus-independent thoughtMalia F Mason
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Science 315:393-5. 2007..quot; In addition, individuals' reports of the tendency of their minds to wander were correlated with activity in this network... - Actions or hand-object interactions? Human inferior frontal cortex and action observationScott H Johnson-Frey
Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Neuron 39:1053-8. 2003..Bilaterally, precentral gyrus was most frequently activated (82%) followed by pars triangularis (73%) and pars opercularis (65%)... - From 'acting on' to 'acting with': the functional anatomy of object-oriented action schemataScott H Johnson
Center for Cognitive Neuroscience, Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Prog Brain Res 142:127-39. 2003..Specifically, it is argued that conceptual knowledge of tool use and the pragmatics of action rely on an inferior parieto-medial frontal network in the left hemisphere... - Neural substrates of practice structure that support future off-line learningNicholas F Wymbs
1Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire, USA
J Neurophysiol 102:2462-76. 2009.... - From facial cue to dinner for two: the neural substrates of personal choiceDavid J Turk
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Neuroimage 22:1281-90. 2004..The implications of these findings for current accounts of response selection and social-cognitive functioning are considered... - Sharing neuroimaging studies of human cognitionJohn Darrell Van Horn
Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Neurosci 7:473-81. 2004..Thus, the field of neuroimaging is following the lead of biology and chemistry, mining its accumulating body of knowledge and moving toward a 'discovery science' of brain function... - Neural substrates of contextual interference during motor learning support a model of active preparationEmily S Cross
Dartmouth College, USA
J Cogn Neurosci 19:1854-71. 2007..This pattern of recruitment is consistent with the hypothesis that CI benefits in a sequencing task are due to improved capacity to actively prepare motor responses... - Functional imaging of face and hand imitation: towards a motor theory of empathyKenneth R Leslie
Department of Psychological and Brain Sciences and Center for Cognitive Neurosciences, Dartmouth College, Hanover NH 03755, USA
Neuroimage 21:601-7. 2004..This result is consistent with evidence for right hemisphere (RH) dominance for emotional processing, and suggests that there may be a right hemisphere mirroring system that could provide a neural substrate for empathy... - Where does your own action influence your perception of another person's action in the brain?Antonia F de C Hamilton
Department of Psychological and Brain Sciences, Dartmouth College, 6162 Moore Hall, Dartmouth College, Hanover, NH 03755, USA
Neuroimage 29:524-35. 2006.... - Cortical topography of human anterior intraparietal cortex active during visually guided graspingScott H Frey
Department of Psychology, University of Oregon, HB 6162, Moore Hall, Dartmouth College, Hanover, NH 03755, USA
Brain Res Cogn Brain Res 23:397-405. 2005..In both humans and macaques this region appears to play a key role in visually guided grasping... - Structural organization of the corpus callosum predicts the extent and impact of cortical activity in the nondominant hemisphereMary Colvin Putnam
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
J Neurosci 28:2912-8. 2008.... - Correlation between insula activation and self-reported quality of orgasm in womenStephanie Ortigue
Dartmouth Brain Imaging Center, Center for Cognitive Neuroscience, Dartmouth College, 6162 Moore Hall, Hanover, NH, USA
Neuroimage 37:551-60. 2007.... - Selective activation of a parietofrontal circuit during implicitly imagined prehensionS H Johnson
Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755-3569, USA
Neuroimage 17:1693-704. 2002..Because these areas are highly consistent with the frontoparietal reach circuit identified in monkeys, we conclude that motor imagery involves action-specific motor representations computed in parietofrontal circuits... - Medial temporal lobe BOLD activity at rest predicts individual differences in memory ability in healthy young adultsGagan S Wig
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Proc Natl Acad Sci U S A 105:18555-60. 2008.... - Swinging in the brain: shared neural substrates for behaviors related to sequencing and musicPetr Janata
Center for Cognitive Neuroscience, Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Neurosci 6:682-7. 2003..These studies are also brought into an existing framework concerning the interaction of attention and time-keeping mechanisms in perceiving complex patterns of information that are distributed in time, such as those that occur in music... - Motor experience with graspable objects reduces their implicit analysis in visual- and motor-related cortexTodd C Handy
Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC Canada V6T 1Z4
Brain Res 1097:156-66. 2006..Taken together, these data support the proposal that repeated real-world motor experience with an object category may lead to reduced implicit analysis in both motor- and visual-related regions of cortex... - The functional anatomy of parkinsonian bradykinesiaRobert S Turner
Department of Neurology, Emory University School of Medicine, WMRB 6000, Atlanta, GA 30322, USA
Neuroimage 19:163-79. 2003..The overactivation of cortical regions observed in patients may be functional correlates of compensatory mechanisms and/or impaired suppression as a facet of the primary pathophysiology of PD... - Motor subcircuits mediating the control of movement extent and speedRobert S Turner
Department of Neurology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
J Neurophysiol 90:3958-66. 2003..We conclude that a small subcircuit within the motor control system contributes to the control of movement extent and covariates and that the BG and cerebellum play central roles in the operation of that circuit... - Neural substrates of response-based sequence learning using fMRIAmanda Bischoff-Grethe
San Diego VA Healthcare System, San Diego, CA, USA
J Cogn Neurosci 16:127-38. 2004..Retrieval of sequential responses occurs within mesial motor areas and related motor planning areas... - Malleable templates: reshaping our crystallized skills to create new outcomesScott T Grafton
Nat Neurosci 11:248-9. 2008 - A distributed left hemisphere network active during planning of everyday tool use skillsScott H Johnson-Frey
Department of Psychology, University of Oregon, Eugene, OR 97403 1227, USA
Cereb Cortex 15:681-95. 2005..We suggest that this left lateralized network constitutes a neural substrate for the interaction of semantic and motoric representations upon which meaningful skills depend... - Evidence for a distributed hierarchy of action representation in the brainScott T Grafton
Department of Psychology, Room 3837, Building 251, University of California, Santa Barbara, CA 93106, United States
Hum Mov Sci 26:590-616. 2007.... - Effect of methylphenidate on executive functioning in adults with attention-deficit/hyperactivity disorder: normalization of behavior but not related brain activityJulie B Schweitzer
Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA
Biol Psychiatry 56:597-606. 2004..We examined the effect of prolonged methylphenidate (MPH) treatment on the functional neuroanatomy of executive functioning in adult men with attention-deficit/hyperactivity disorder (ADHD)... - The angular gyrus computes action awareness representationsChloe Farrer
Centre de Neuroscience Cognitive, Universite Claude Bernard Lyon 1, CNRS, 69675 Lyon, France
Cereb Cortex 18:254-61. 2008..This joint processing is at the core of the various experiences one uses to interpret an action... - Placing a tool in the spotlight: spatial attention modulates visuomotor responses in cortexTodd C Handy
Department of Psychology, University of British Columbia, Vancouver, Canada
Neuroimage 26:266-76. 2005.... - Updating target location at the end of an orienting saccade affects the characteristics of simple point-to-point movementsMichel Desmurget
Institut National de la Sante et de la Recherche Medicale INSERM, Bron, France
J Exp Psychol Hum Percept Perform 31:1510-36. 2005..Together these data show that movements with straight paths and bell-shaped velocity profiles are not necessarily ballistic... - Anatomical substrates of visual and auditory miniature second-language learningRoger D Newman-Norlund
Dartmouth College corrected
J Cogn Neurosci 18:1984-97. 2006..quot; The right frontal cortex was not preferentially recruited by visual language after accounting for phonetic/structural complexity and performance... - A positron emission tomography study of methylphenidate in adults with ADHD: alterations in resting blood flow and predicting treatment responseJulie B Schweitzer
Maryland Psychiatric Research Center and Division of Child Psychiatry, University of Maryland School of Medicine, White Building, PO Box 21247, Baltimore, MD 21228, USA
Neuropsychopharmacology 28:967-73. 2003..The majority of these brain regions are involved in the planning and execution of motor behavior. These data suggest that MPH modulates brain regions associated with motor function to achieve a reduction in ADHD symptoms... - Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNTMargaret R Davis
PET Center, Emory University, Atlanta, Georgia, USA
J Nucl Med 44:855-61. 2003..Having picked up presymptomatic changes in the hemisphere opposite the unaffected side of the body in our early-stage (unilateral) PD patients, it appears that, like other DAT radioligands, it may be able to identify presymptomatic PD... - Doing more with less: the plight of the failing hippocampusScott T Grafton
Ann Neurol 56:7-9. 2004