ALAN R EASTMAN

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi request reprint A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01
    Alan Eastman
    Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, USA
    Mol Cancer Ther 1:1067-78. 2002
  2. ncbi request reprint Cell cycle checkpoints and their impact on anticancer therapeutic strategies
    Alan Eastman
    Department of Pharmacology, and the Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Cell Biochem 91:223-31. 2004

Collaborators

Detail Information

Publications2

  1. ncbi request reprint A novel indolocarbazole, ICP-1, abrogates DNA damage-induced cell cycle arrest and enhances cytotoxicity: similarities and differences to the cell cycle checkpoint abrogator UCN-01
    Alan Eastman
    Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, USA
    Mol Cancer Ther 1:1067-78. 2002
    ..Hence, ICP-1 appears to be a more selective inhibitor of the S and G2 cell cycle checkpoint than previously studied analogues and is worthy of study in preclinical tumor models...
  2. ncbi request reprint Cell cycle checkpoints and their impact on anticancer therapeutic strategies
    Alan Eastman
    Department of Pharmacology, and the Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Cell Biochem 91:223-31. 2004
    ..However, these defects also represent an Achilles heel that can be targeted to improve current therapeutic strategies...