B F Cole

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. ncbi request reprint Folic acid for the prevention of colorectal adenomas: a randomized clinical trial
    Bernard F Cole
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
    JAMA 297:2351-9. 2007
  2. ncbi request reprint A quality-adjusted survival (Q-TWiST) model for evaluating treatments for advanced stage cancer
    Bernard F Cole
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hamphire, USA
    J Biopharm Stat 14:111-24. 2004
  3. ncbi request reprint Polychemotherapy for early breast cancer: an overview of the randomised clinical trials with quality-adjusted survival analysis
    B F Cole
    Dartmouth College Medical School, Lebanon, NH, USA
    Lancet 358:277-86. 2001
  4. ncbi request reprint Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial
    Maria V Grau
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
    J Natl Cancer Inst 99:129-36. 2007
  5. ncbi request reprint Quality-of-life-adjusted survival analysis of interferon alfa-2b treatment for advanced follicular lymphoma: an aid to clinical decision making
    B F Cole
    Dartmouth Medical School, Lebanon, NH 03756, USA
    J Clin Oncol 16:2339-44. 1998
  6. ncbi request reprint Phase I pilot trial of the bispecific antibody MDXH210 (anti-Fc gamma RI X anti-HER-2/neu) in patients whose prostate cancer overexpresses HER-2/neu
    T Schwaab
    Uro-Oncology Program, Norris Cotton Cancer Center and Section of Urology and Immunology and Immunotherapy Research Programs, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA
    J Immunother 24:79-87. 2001
  7. ncbi request reprint Pharmacokinetic-pharmacodynamic relationships of the bispecific antibody MDX-H210 when administered in combination with interferon gamma: a multiple-dose phase-I study in patients with advanced cancer which overexpresses HER-2/neu
    L D Lewis
    Department of Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    J Immunol Methods 248:149-65. 2001
  8. ncbi request reprint A multistate Markov chain model for longitudinal, categorical quality-of-life data subject to non-ignorable missingness
    Bernard F Cole
    Department of Community and Family Medicine, Section of Biostatistics and Epidemiology, Dartmouth College Medical School, Lebanon, NH 03756, USA
    Stat Med 24:2317-34. 2005
  9. ncbi request reprint Pigmentary characteristics and moles in relation to melanoma risk
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Int J Cancer 116:144-9. 2005
  10. ncbi request reprint SunSafe in the Middle School Years: a community-wide intervention to change early-adolescent sun protection
    Ardis L Olson
    Department of Pediatrics, Dartmouth Medical School, Norris Cotton Cancer Center, Lebanon, New Hampshire, USA
    Pediatrics 119:e247-56. 2007

Detail Information

Publications44

  1. ncbi request reprint Folic acid for the prevention of colorectal adenomas: a randomized clinical trial
    Bernard F Cole
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
    JAMA 297:2351-9. 2007
    ..Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine...
  2. ncbi request reprint A quality-adjusted survival (Q-TWiST) model for evaluating treatments for advanced stage cancer
    Bernard F Cole
    Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hamphire, USA
    J Biopharm Stat 14:111-24. 2004
    ..Finally a single summary analysis is achieved by averaging (possibly with weights) across the cut-offs used. We illustrate the methodology using data from a cancer clincial trial...
  3. ncbi request reprint Polychemotherapy for early breast cancer: an overview of the randomised clinical trials with quality-adjusted survival analysis
    B F Cole
    Dartmouth College Medical School, Lebanon, NH, USA
    Lancet 358:277-86. 2001
    ..Here we express the size of the benefit in terms of quality-adjusted survival time gained...
  4. ncbi request reprint Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial
    Maria V Grau
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
    J Natl Cancer Inst 99:129-36. 2007
    ..Calcium supplementation has been shown to decrease the risk of recurrence of colorectal adenomas in randomized trials. However, the duration of this protective effect after cessation of active supplementation is not known...
  5. ncbi request reprint Quality-of-life-adjusted survival analysis of interferon alfa-2b treatment for advanced follicular lymphoma: an aid to clinical decision making
    B F Cole
    Dartmouth Medical School, Lebanon, NH 03756, USA
    J Clin Oncol 16:2339-44. 1998
    ..To evaluate the trade-off of toxicity versus improved clinical outcome with interferon alfa-2b (IFN) administered concomitantly with a doxorubicin-containing regimen for the treatment of advanced follicular lymphoma...
  6. ncbi request reprint Phase I pilot trial of the bispecific antibody MDXH210 (anti-Fc gamma RI X anti-HER-2/neu) in patients whose prostate cancer overexpresses HER-2/neu
    T Schwaab
    Uro-Oncology Program, Norris Cotton Cancer Center and Section of Urology and Immunology and Immunotherapy Research Programs, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA
    J Immunother 24:79-87. 2001
    ....
  7. ncbi request reprint Pharmacokinetic-pharmacodynamic relationships of the bispecific antibody MDX-H210 when administered in combination with interferon gamma: a multiple-dose phase-I study in patients with advanced cancer which overexpresses HER-2/neu
    L D Lewis
    Department of Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    J Immunol Methods 248:149-65. 2001
    ..MDX-H210 is a Fab'xFab' bispecific antibody (BsAb) constructed chemically by crosslinking Fab' mAb 520C9 (anti-HER-2/neu) and Fab' mAbH22 (anti-CD64)...
  8. ncbi request reprint A multistate Markov chain model for longitudinal, categorical quality-of-life data subject to non-ignorable missingness
    Bernard F Cole
    Department of Community and Family Medicine, Section of Biostatistics and Epidemiology, Dartmouth College Medical School, Lebanon, NH 03756, USA
    Stat Med 24:2317-34. 2005
    ..We apply the techniques to data from a breast cancer clinical trial in which QOL assessments were made longitudinally, and in which missing data frequently arose...
  9. ncbi request reprint Pigmentary characteristics and moles in relation to melanoma risk
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Int J Cancer 116:144-9. 2005
    ....
  10. ncbi request reprint SunSafe in the Middle School Years: a community-wide intervention to change early-adolescent sun protection
    Ardis L Olson
    Department of Pediatrics, Dartmouth Medical School, Norris Cotton Cancer Center, Lebanon, New Hampshire, USA
    Pediatrics 119:e247-56. 2007
    ..Our study objective was to determine if a multicomponent community-wide intervention could alter the decline in sun protection that begins in early adolescence...
  11. pmc Factors affecting the detection rate of human papillomavirus
    Diane M Harper
    Department of Obstetrics and Gynecology, Dartmouth Medical School, Hanover, NH, USA
    Ann Fam Med 1:221-7. 2003
    ..The purpose of this study was to determine whether cyclic hormonal variation, recent sexual intercourse, interval between samplings, and the technique used to sample affect the detection of HPV...
  12. ncbi request reprint Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trial
    John A Baron
    Department of Medicine, Dartmouth Medical School, Evergreen Center, Lebanon, NH 03766, USA
    J Natl Cancer Inst 95:717-22. 2003
    ..Although beta-carotene supplementation appeared not to increase the risk of cancer generally, it is not clear if smoking and/or alcohol use alters the effect of beta-carotene on carcinogenesis at sites outside the lung...
  13. ncbi request reprint Factors associated with atypical moles in New Hampshire, USA
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Acta Derm Venereol 87:43-8. 2007
    ..Our data indicate that freckles and benign moles, which may reflect melanocytic inducibility, are strongly associated with atypical moles. The inverse association with sun exposure should be considered with caution...
  14. doi request reprint Offspring of women exposed in utero to diethylstilbestrol (DES): a preliminary report of benign and malignant pathology in the third generation
    Linda Titus-Ernstoff
    Department of Community and Family Medicine, Dartmouth Medical School, and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Epidemiology 19:251-7. 2008
    ..Specifically, these studies show an elevated incidence of reproductive tumors in the female offspring of prenatally-exposed mice...
  15. ncbi request reprint A randomized trial of aspirin to prevent colorectal adenomas
    John A Baron
    Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    N Engl J Med 348:891-9. 2003
    ..Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel...
  16. ncbi request reprint Tampon samplings with longer cervicovaginal cell exposures are equivalent to two consecutive swabs for the detection of high-risk human papillomavirus
    Diane M Harper
    Department of Obstetrics and Gynecology, Dartmouth Medical School, Hanover, New Hampshire, USA
    Sex Transm Dis 29:628-36. 2002
    ..Self-sampling for human papillomavirus (HPV) is useful for triage of ASCUS Papanicolaou (Pap) smears. Tampons with 10-second cervicovaginal cell exposure can detect HPV but appear to be less efficient than two consecutive swabs...
  17. ncbi request reprint The pharmacokinetics of the bispecific antibody MDX-H210 when combined with interferon gamma-1b in a multiple-dose phase I study in patients with advanced cancer
    Lionel D Lewis
    Department of Medicine, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
    Cancer Chemother Pharmacol 49:375-84. 2002
    ..MDX-H210 is a Fab'xFab' bispecific antibody (BsAb) constructed chemically by crosslinking Fab' mAb 520C9 (anti-HER-2/neu) and humanized Fab' mAbH22 (anti-CD64)...
  18. ncbi request reprint Interaction of calcium supplementation and nonsteroidal anti-inflammatory drugs and the risk of colorectal adenomas
    Maria V Grau
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hamsphire, USA
    Cancer Epidemiol Biomarkers Prev 14:2353-8. 2005
    ..Calcium and aspirin have both been found to be chemopreventive against colorectal neoplasia. However, the joint effect of the two agents has not been well investigated...
  19. ncbi request reprint Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines
    John P Mongan
    Department of Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Clin Colorectal Cancer 8:100-5. 2009
    ....
  20. ncbi request reprint Prediagnostic serum selenium concentration and the risk of recurrent colorectal adenoma: a nested case-control study
    Kristin Wallace
    Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
    Cancer Epidemiol Biomarkers Prev 12:464-7. 2003
    ..50 for total selenium and P for trend = 0.20 for bound selenium). Thus, our findings do not indicate a clear association between serum selenium concentrations and adenoma recurrence...
  21. ncbi request reprint Effect of calcium supplementation on the risk of large bowel polyps
    Kristin Wallace
    Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Natl Cancer Inst 96:921-5. 2004
    ..However, few studies have examined the effect of calcium on the risk of different types of colorectal lesions or dietary determinants of this effect...
  22. ncbi request reprint Randomized clinical trial of PCR-determined human papillomavirus detection methods: self-sampling versus clinician-directed--biologic concordance and women's preferences
    Diane M Harper
    Department of Obstetrics and Gynecology, Dartmouth Medical School, Hannover, NH, USA
    Am J Obstet Gynecol 186:365-73. 2002
    ..The purpose of this study was to compare the high-risk human papillomavirus detection rates from self-sampled swabs and tampons with standard clinician-directed speculum sampling and to assess women's acceptance of self-sampling methods...
  23. ncbi request reprint Quality-of-life-adjusted survival comparison of sustained-release cytosine arabinoside versus intrathecal methotrexate for treatment of solid tumor neoplastic meningitis
    Bernard F Cole
    Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire, USA
    Cancer 97:3053-60. 2003
    ..The authors evaluated the trade-off between toxicity and improved clinical outcome...
  24. doi request reprint A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme
    Camilo E Fadul
    Department of Medicine, Section of Hematology Oncology, Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center Drive, One Medical Center Drive, Lebanon, NH 03756, USA
    J Neurooncol 90:229-35. 2008
    ..To evaluate the combination of thalidomide and irinotecan, we conducted a phase II trial in adults with newly-diagnosed or recurrent GBM...
  25. pmc A controlled trial of methods for managing pain in primary care patients with or without co-occurring psychosocial problems
    Tim A Ahles
    Department of Psychiatry, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Ann Fam Med 4:341-50. 2006
    ..Pain, a common reason for visits to primary care physicians, is often not well managed. The objective of this study was to determine the effectiveness of pain management interventions suitable for primary care physicians...
  26. pmc Clinical and immunologic effects of intranodal autologous tumor lysate-dendritic cell vaccine with Aldesleukin (Interleukin 2) and IFN-{alpha}2a therapy in metastatic renal cell carcinoma patients
    Thomas Schwaab
    Medical Oncology Immunotherapy Group, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA
    Clin Cancer Res 15:4986-92. 2009
    ..To evaluate the clinical and immunologic outcomes of DC (dendritic cell) vaccine with interleukin (IL)-2 and IFN-alpha 2a in metastatic renal cell carcinoma patients...
  27. doi request reprint A prospective, multi-institutional study of adjuvant radiotherapy after resection of malignant phyllodes tumors
    Richard J Barth
    Department of Surgery, Section of General Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Ann Surg Oncol 16:2288-94. 2009
    ..It is uncertain whether radiotherapy after resection of phyllodes tumors is beneficial...
  28. pmc Cognitive function in breast cancer patients prior to adjuvant treatment
    Tim A Ahles
    Department of Psychiatry and Center for Psycho Oncology, The Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center Lebanon, Lebanon, NH, USA
    Breast Cancer Res Treat 110:143-52. 2008
    ..To compare the neuropsychological functioning of breast cancer patients with invasive cancer and noninvasive cancer prior to adjuvant treatment...
  29. ncbi request reprint The association of physical activity and body mass index with the risk of large bowel polyps
    Kristin Wallace
    Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Cancer Epidemiol Biomarkers Prev 14:2082-6. 2005
    ..After the second study colonoscopy, we asked subjects questions about their leisure time physical activity. Seven hundred eighty-seven subjects completed at least part of the physical activity questionnaire...
  30. ncbi request reprint Docetaxel/Gemcitabine followed by gemcitabine and external beam radiotherapy in patients with pancreatic adenocarcinoma
    J Marc Pipas
    Gastrointestinal Oncology Program, Dartmouth Hitchcock Medical Center Norris Cotton Cancer Center, One Medical Center Drive, Lebanon, NH 03756, USA
    Ann Surg Oncol 12:995-1004. 2005
    ..We conducted a phase II trial of dose-intense docetaxel and gemcitabine followed by twice-weekly gemcitabine and external beam radiotherapy in patients with pancreatic adenocarcinoma...
  31. ncbi request reprint Tumor-related immunity in prostate cancer patients treated with human recombinant granulocyte monocyte-colony stimulating factor (GM-CSF)
    Thomas Schwaab
    Uro oncology Group, Norris Cotton Cancer Center NCCC at Dartmouth Hitchcock Medical Center DHMC, NH, Lebanon
    Prostate 66:667-74. 2006
    ..We hypothesized that systemic therapy with GM-CSF in prostate cancer patients could augment prostate cancer-related immunity and induce clinical response...
  32. ncbi request reprint Expression of "Spot 14" (THRSP) predicts disease free survival in invasive breast cancer: immunohistochemical analysis of a new molecular marker
    Wendy A Wells
    Department of Pathology, Dartmouth Medical School, Lebanon, NH 03756, USA
    Breast Cancer Res Treat 98:231-40. 2006
    ....
  33. ncbi request reprint Colorectal cancer in patients under close colonoscopic surveillance
    Douglas J Robertson
    Section of Gastroenterology, VA Medical Center, White River Junction, Vermont 05009, USA
    Gastroenterology 129:34-41. 2005
    ..We determined the incidence of CRC in patients under colonoscopic surveillance and examined the circumstances and risk factors for CRC and adenoma with high-grade dysplasia...
  34. pmc MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trial
    A Joan Levine
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 17:2409-15. 2008
    ..Our findings indicate that the MTHFR genotype does not change adenoma risk in a manner similar to its effect on colorectal cancer, and does not modify the effect of folate supplementation on metachronous adenoma risk...
  35. doi request reprint Another STEPP in the right direction
    Marco Bonetti
    J Clin Oncol 26:3813-4; author reply 3814-5. 2008
  36. ncbi request reprint Aspirin may be more effective in preventing colorectal adenomas in patients with higher BMI (United States)
    Sangmi Kim
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7555, USA
    Cancer Causes Control 17:1299-304. 2006
    ..The more pronounced effect of 325 mg aspirin in individuals with higher BMI suggests a possible protective role of anti-inflammatory aspirin against increased adipose-driven cytokines among obese subjects...
  37. ncbi request reprint Anemia during adjuvant non-taxane chemotherapy for early breast cancer: Incidence and risk factors from two trials of the International Breast Cancer Study Group
    Lorenzo Gianni
    Divisione di Oncologia e di Ematologia, Ospedale degli Infermi, and Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Azienda USL Rimini Via Settembrini 2, Rimini, Italy
    Support Care Cancer 16:67-74. 2008
    ..The objective of this study was to evaluate the incidence of anemia and risk factors for anemia occurrence in patients with early breast cancer who received adjuvant chemotherapy...
  38. ncbi request reprint Quality-of-life-adjusted survival analysis of high-dose adjuvant interferon alpha-2b for high-risk melanoma patients using intergroup clinical trial data
    Kerry L Kilbridge
    Department of Health Evaluation Sciences, University of Virginia Health System, Charlottesville, VA 22908 0821, USA
    J Clin Oncol 20:1311-8. 2002
    ....
  39. ncbi request reprint Analyzing oncology clinical trial data using the Q-TWiST method: clinical importance and sources for health state preference data
    Dennis A Revicki
    Center for Health Outcomes Research, MEDTAP Institute, 7101 Wisconsin Avenue, Suite 600, Bethesda, MD 20814, USA
    Qual Life Res 15:411-23. 2006
    ..We also provide recommendations for measuring health utilities and for the design of Q-TWiST studies...
  40. pmc Cognitive-behavioral management of chemotherapy-related cognitive change
    Robert J Ferguson
    Department of Rehabilitation Medicine, Eastern Maine Medical Center, Bangor, ME 04401, USA
    Psychooncology 16:772-7. 2007
    ..Given these results, the treatment appears to be a feasible and practical cognitive-behavioral program that warrants continued evaluation among cancer survivors who experience persistent cognitive dysfunction...
  41. ncbi request reprint The role of the number of uninvolved lymph nodes in predicting locoregional recurrence in breast cancer
    Per Karlsson
    Department of Oncology, University of Goteborg, Sahlgrenska University Hospital, Goteborg, Sweden
    J Clin Oncol 25:2019-26. 2007
    ..To identify groups of early breast cancer patients with substantial risk (10-year risk > 20%) for locoregional failure (LRF) who might benefit from postmastectomy radiotherapy (RT)...
  42. ncbi request reprint Maternal androgen and estrogen concentrations are not associated with blood pressure changes in uncomplicated pregnancies
    Rebecca Troisi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Bethesda, MD 20892 7246, USA
    Cancer Epidemiol Biomarkers Prev 15:2013-5. 2006
    ..These data are not consistent with the hypothesis that elevated androgen concentrations mediate the observed reduction in maternal breast cancer risk associated with increases in blood pressure over the pregnancy...
  43. ncbi request reprint Boost radiotherapy in young women with ductal carcinoma in situ: a multicentre, retrospective study of the Rare Cancer Network
    Aurelius Omlin
    Department of Radiation Oncology, University of Bern, Inselspital, Bern, Switzerland
    Lancet Oncol 7:652-6. 2006
    ..Outcome data in young women with ductal carcinoma in situ (DCIS) are rare. The benefits of boost radiotherapy in this group are also unknown. We aimed to assess the effect of boost radiotherapy in young patients with DCIS...
  44. pmc Basis for treatment of tuberculosis among HIV-infected patients in Tanzania: the role of chest x-ray and sputum culture
    Muhammad Bakari
    Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    BMC Infect Dis 8:32. 2008
    ..We sought to determine the role of chest x-ray and sputum culture in the decision to treat for presumptive TB using active case finding in a large cohort of HIV-infected patients...