Elizabeth L R Barry
Affiliation: Dartmouth Medical School
- CYP2C9 variants increase risk of colorectal adenoma recurrence and modify associations with smoking but not aspirin treatmentElizabeth L Barry
Geisel School of Medicine at Dartmouth, Lebanon, NH, USA
Cancer Causes Control 24:47-54. 2013..Two common nonsynonymous polymorphisms in CYP2C9 are associated with reduced enzyme activity: CYP2C9*2 (rs1799853, R144C) and CYP2C9*3 (rs1057910, I359L)...
- K-ras mutations in incident sporadic colorectal adenomasElizabeth L R Barry
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire 03766, USA
Cancer 106:1036-40. 2006..In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas that occurred during a chemoprevention trial of calcium supplementation...
- Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma preventionElizabeth L R Barry
Department of Community and Family Medicine, Dartmouth Medical School, 46 Centerra Parkway, Ste 300, Lebanon, NH 03766, USA
J Natl Cancer Inst 98:1494-500. 2006..Previous research suggests that the G315A single-nucleotide polymorphism in the ornithine decarboxylase (ODC) gene may be a genetic marker for risk of colorectal neoplasia and may also modify the association of aspirin use with risk...
- Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trialElizabeth L Barry
Department of Community and Family Medicine, Dartmouth Medical School, Suite 300, Evergreen Center, 46 Centerra Parkway, Lebanon, NH 03756, USA
Cancer Epidemiol Biomarkers Prev 18:2726-33. 2009..These results support the hypothesis that COX-2 plays a role in the etiology of colon cancer and may be a target for aspirin chemoprevention and warrant further investigation in other colorectal adenoma and cancer populations...
- Variants downstream of the ornithine decarboxylase gene influence risk of colorectal adenoma and aspirin chemopreventionElizabeth L Barry
Department of Community and Family Medicine, Dartmouth Medical School, 46 Centerra Parkway, Suite 300, Lebanon, NH 03766, USA
Cancer Prev Res (Phila) 4:2072-82. 2011..Our findings suggest that common genetic variants located downstream (3') of the ODC gene influence risk of colorectal adenoma and may also impact the efficacy of aspirin chemoprevention...