Research Topics
Species | JOHN ANTHONY BARONSummaryAffiliation: Dartmouth Medical School Country: USA Publications
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Publications
Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPsBoris Pasche
Division of Hematology Oncology, The University of Alabama at Birmingham and UAB Comprehensive Cancer Center, Birmingham, AL 35203, USA
J Exp Clin Cancer Res 29:57. 2010..This phenotype was first observed in mice, then in lymphoblastoid cell lines from patients with microsatellite stable colorectal tumors...- Prescriptions for selective cyclooxygenase-2 inhibitors, non-selective non-steroidal anti-inflammatory drugs, and risk of breast cancer in a population-based case-control studyDeirdre P Cronin-Fenton
Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, Aarhus N, Denmark
Breast Cancer Res 12:R15. 2010.... - Oestrogen receptor alpha gene haplotype and postmenopausal breast cancer risk: a case control studySara Wedren
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Breast Cancer Res 6:R437-49. 2004..Because breast cancer development is dependent on oestrogenic influence, we have investigated whether polymorphisms in the oestrogen receptor alpha gene (ESR1) are associated with breast cancer risk... - Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control studySara Wedren
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
BMC Cancer 8:322. 2008..One of the most important mediators of estrogenic action is the estrogen receptor alpha. We have investigated whether polymorphic variation in the estrogen receptor alpha gene (ESR1) is associated with endometrial cancer risk... 
Epidemiology of non-steroidal anti-inflammatory drugs and cancerJohn A Baron
Departments of Medicine, and Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, N H, USA
Prog Exp Tumor Res 37:1-24. 2003..Nonetheless, with the increased understanding of the clinical effects of NSAIDs on cancer, the development of effective chemoprevention with these drugs appears to be a real possibility...- A randomized trial of aspirin to prevent colorectal adenomasJohn A Baron
Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
N Engl J Med 348:891-9. 2003..Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel... - A randomized trial of rofecoxib for the chemoprevention of colorectal adenomasJohn A Baron
Department of Medicine, The Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, New Hampshire, USA
Gastroenterology 131:1674-82. 2006..We conducted a randomized, placebo-controlled, double-blind trial to assess whether use of the selective COX-2 inhibitor rofecoxib would reduce the risk of colorectal adenomas... - Association between folate levels and CpG Island hypermethylation in normal colorectal mucosaKristin Wallace
Department of Medicine, Dartmouth Medical School, Evergreen Center, Lebanon, NH 03756, USA
Cancer Prev Res (Phila) 3:1552-64. 2010..These data have important implications regarding the safety of supplementary folate administration in healthy adults, given the hypothesis that methylation in normal mucosa may predispose to colorectal neoplasia... - Nonsteroidal anti-inflammatory drugs and cancer preventionJ A Baron
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
Annu Rev Med 51:511-23. 2000..The mechanisms underlying any chemopreventive effect of NSAIDs are not clear. Inhibition of cyclooxygenase is one possibility, but pathways independent of cyclooxygenase and prostaglandins are also possible... - Aspirin and NSAIDs for the prevention of colorectal cancerJohn A Baron
Evergreen Center, Biostatistics and Epidemiology, Lebanon, NH 03756, USA
Recent Results Cancer Res 181:223-9. 2009..Together these data provide convincing evidence for the chemopreventive efficacy ofNSAIDs in the large bowel... 
Statins and the colorectum: hope for chemoprevention?John A Baron
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
Cancer Prev Res (Phila) 3:573-5. 2010..The perspective discusses the implications of these data and how they fit into the context of previous investigations...- Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trialJohn A Baron
Department of Medicine, Dartmouth Medical School, Evergreen Center, Lebanon, NH 03766, USA
J Natl Cancer Inst 95:717-22. 2003..Although beta-carotene supplementation appeared not to increase the risk of cancer generally, it is not clear if smoking and/or alcohol use alters the effect of beta-carotene on carcinogenesis at sites outside the lung... - Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trialMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
J Natl Cancer Inst 99:129-36. 2007..Calcium supplementation has been shown to decrease the risk of recurrence of colorectal adenomas in randomized trials. However, the duration of this protective effect after cessation of active supplementation is not known... - A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancerRobert S Sandler
Department of Medicine, University of North Carolina, Chapel Hill 27599 7555, USA
N Engl J Med 348:883-90. 2003..Experimental studies in animals and observational studies in humans suggest that regular aspirin use may decrease the risk of colorectal adenomas, the precursors to most colorectal cancers... - The association of lifestyle and dietary factors with the risk for serrated polyps of the colorectumKristin Wallace
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, New Hamsphire, USA
Cancer Epidemiol Biomarkers Prev 18:2310-7. 2009..Our results suggest that several common lifestyle and dietary variables are associated with risk for serrated polyps, and some of these may differ for the right and left colorectum... - Effect of calcium supplementation on the risk of large bowel polypsKristin Wallace
Department of Community and Family Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA
J Natl Cancer Inst 96:921-5. 2004..CONCLUSION: Our results suggest that calcium supplementation may have a more pronounced antineoplastic effect on advanced colorectal lesions than on other types of polyps... - Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trialJohn A Baron
Departments of Medicine, and of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
Lancet 372:1756-64. 2008..We report the cardiovascular outcomes of a long-term follow-up of participants in the trial... - Fat, fiber, meat and the risk of colorectal adenomasDouglas J Robertson
Veterans Hospital, White River Junction, Vermont, and Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
Am J Gastroenterol 100:2789-95. 2005..98). CONCLUSION: The inverse associations between fiber intake and risk of adenoma recurrence we observed are weak, and not statistically significant. Our data indicate that intake of specific meats may have different effects on risk... - Risk of prostate cancer in a randomized clinical trial of calcium supplementationJohn A Baron
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire, USA
Cancer Epidemiol Biomarkers Prev 14:586-9. 2005..CONCLUSION: In this randomized controlled clinical trial, there was no increase in prostate cancer risk associated with calcium supplementation and some suggestion of a protective effect... - Acute effects of nicotine on serum glucose insulin growth hormone and cortisol in healthy smokersThomas M Morgan
Dartmouth Medical School and Dartmouth-Hitchcock Medical Center, Hannover, NH, USA
Metabolism 53:578-82. 2004..Further research is needed to determine the clinical implications of the unexpected finding that nicotine decreased growth hormone levels in female smokers... - Prediagnostic serum selenium concentration and the risk of recurrent colorectal adenoma: a nested case-control studyKristin Wallace
Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
Cancer Epidemiol Biomarkers Prev 12:464-7. 2003..50 for total selenium and P for trend = 0.20 for bound selenium). Thus, our findings do not indicate a clear association between serum selenium concentrations and adenoma recurrence... - Effect of NSAIDs on the recurrence of nonmelanoma skin cancerMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03766, USA
Int J Cancer 119:682-6. 2006..There were some indications of a modest, nonsignificant reduction on the number of BCCs and SCCs with NSAID use. Our data suggest a weak and inconsistent chemopreventive effect of NSAIDs on BCC and SCC... - K-ras mutations in incident sporadic colorectal adenomasElizabeth L R Barry
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hampshire 03766, USA
Cancer 106:1036-40. 2006..In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas that occurred during a chemoprevention trial of calcium supplementation... - Mortality and pulmonary embolism after fracture in the elderlyJane A Barrett
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH 03755, USA
Osteoporos Int 14:889-94. 2003..6 to 1.8, and for patients with proximal humerus fractures the risk ratio was 1.4. All lower-limb fractures carried a higher risk of PE than any upper-limb fracture... - Nonsteroidal anti-inflammatory drug use after 3 years of aspirin use and colorectal adenoma risk: observational follow-up of a randomized studyMaria V Grau
Departments of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
J Natl Cancer Inst 101:267-76. 2009..We examined the persistence of the protective effect after the cessation of randomized aspirin treatment and whether it is affected by the duration and frequency of subsequent NSAID use... - Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma preventionElizabeth L R Barry
Department of Community and Family Medicine, Dartmouth Medical School, 46 Centerra Parkway, Ste 300, Lebanon, NH 03766, USA
J Natl Cancer Inst 98:1494-500. 2006..Previous research suggests that the G315A single-nucleotide polymorphism in the ornithine decarboxylase (ODC) gene may be a genetic marker for risk of colorectal neoplasia and may also modify the association of aspirin use with risk... - Interaction of calcium supplementation and nonsteroidal anti-inflammatory drugs and the risk of colorectal adenomasMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, New Hamsphire, USA
Cancer Epidemiol Biomarkers Prev 14:2353-8. 2005..Calcium and aspirin have both been found to be chemopreventive against colorectal neoplasia. However, the joint effect of the two agents has not been well investigated... - Decreased cancer risk after iron reduction in patients with peripheral arterial disease: results from a randomized trialLeo R Zacharski
Research Service 151, White River Junction VA Medical Center, Department of Veterans Affairs Medical Center, 215 North Hartland Road, White River Junction, VT 05009, USA
J Natl Cancer Inst 100:996-1002. 2008..Excess iron has been implicated in cancer risk through increased iron-catalyzed free radical-mediated oxidative stress... - Survival following total hip replacementJane Barrett
Department of Medicine, Section of Biostatistics and Epidemiology, Dartmouth Medical School, Evergreen Building, Suite 300, 46 Centerra Parkway, Lebanon, NH 03766, USA
J Bone Joint Surg Am 87:1965-71. 2005..The purpose of our investigation was to assess whether the association had the characteristics of a causal relationship or whether it might appear to be due to comorbidity or other factors... - Chemoprevention in gastrointestinal cancers: current statusMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH 03766, USA
Basic Clin Pharmacol Toxicol 98:281-7. 2006..TJ-9, polyprenoic acid and anti-aflatoxin compounds are also possible avenues that deserve future research... - Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease: a randomized controlled trialLeo R Zacharski
White River Junction VA Medical Center, Research Service, Department of Veterans Affairs Medical Center, White River Junction, VT 05001, USA
JAMA 297:603-10. 2007..Accumulation of iron in excess of physiologic requirements has been implicated in risk of cardiovascular disease because of increased iron-catalyzed free radical-mediated oxidative stress... - Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trialElizabeth L Barry
Department of Community and Family Medicine, Dartmouth Medical School, Suite 300, Evergreen Center, 46 Centerra Parkway, Lebanon, NH 03756, USA
Cancer Epidemiol Biomarkers Prev 18:2726-33. 2009..These results support the hypothesis that COX-2 plays a role in the etiology of colon cancer and may be a target for aspirin chemoprevention and warrant further investigation in other colorectal adenoma and cancer populations... - Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trialMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
J Natl Cancer Inst 95:1765-71. 2003..Although these nutrients are inter-related metabolically in bone and in the normal intestine, their potential interactions in large-bowel carcinogenesis are not well understood... - Folic acid for the prevention of colorectal adenomas: a randomized clinical trialBernard F Cole
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
JAMA 297:2351-9. 2007..Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine... - Metabolic and hormonal effects of caffeine: randomized, double-blind, placebo-controlled crossover trialTodd MacKenzie
Department of Medicine, Dartmouth Medical School, Hanover, NH 03755, USA
Metabolism 56:1694-8. 2007..This study provides evidence that daily caffeine intake reduces insulin sensitivity; the effect persists for at least a week and is evident up to 12 hours after administration... - Early life factors in relation to breast cancer risk in postmenopausal womenLinda Titus-Ernstoff
Norris Cotton Cancer Center and the Department of Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Cancer Epidemiol Biomarkers Prev 11:207-10. 2002..Overall, our results are consistent with previous studies and suggest that these early life factors have a modest influence on breast cancer risk in postmenopausal women... - Bilateral total knee replacement: staging and pulmonary embolismJane Barrett
Department of Medicine, Dartmouth Medical School, 46 Centerra Parkway, Evergreen Building, Suite 300, Lebanon, NH 03766, USA
J Bone Joint Surg Am 88:2146-51. 2006..A greater risk of pulmonary embolism after simultaneous total knee replacement has been reported by some authors, but little national data are available... - TGFBR1*6A may contribute to hereditary colorectal cancerYansong Bian
Cancer Genetics Program, Division of Hematology Oncology, Department of Medicine, Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Suite 880, Chicago, IL 60611, USA
J Clin Oncol 23:3074-8. 2005..To test this hypothesis, we determined whether TGFBR16A contributes to a proportion of mismatch repair (MMR) gene mutation-negative hereditary nonpolyposis colorectal cancer (HNPCC) patients... - The association of physical activity and body mass index with the risk of large bowel polypsKristin Wallace
Community and Family Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
Cancer Epidemiol Biomarkers Prev 14:2082-6. 2005..No associations were found between BMI and hyperplastic polyps, tubular adenomas, or advanced neoplastic polyps... - Quality of colonoscopy reporting: a process of care studyDouglas J Robertson
Dartmouth Medical School, Section of Biostatistics and Epidemiology, Lebanon, New Hampshire, USA
Am J Gastroenterol 97:2651-6. 2002..There is an opportunity to improve the quality of care in colonoscopy reporting by improving physicians' adherence to established standards... - Colorectal cancer in patients under close colonoscopic surveillanceDouglas J Robertson
Section of Gastroenterology, VA Medical Center, White River Junction, Vermont 05009, USA
Gastroenterology 129:34-41. 2005..We determined the incidence of CRC in patients under colonoscopic surveillance and examined the circumstances and risk factors for CRC and adenoma with high-grade dysplasia... - Postmenopausal estrogen and progestin use in relation to breast cancer riskPolly A Newcomb
University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin 53706, USA
Cancer Epidemiol Biomarkers Prev 11:593-600. 2002..09; 95% CI, 1.07-4.07 for ever use versus nonuse). Estrogen-progestin use, both sequential and continuous, appears to be more strongly associated with risk of breast cancer than use of estrogen alone... - Rates and outcomes of primary and revision total hip replacement in the United States medicare populationNizar N Mahomed
Toronto Western Hospital, ON, Canada
J Bone Joint Surg Am 85:27-32. 2003..The objective of this study was to characterize the rates and immediate postoperative outcomes of primary and revision total hip replacement in persons sixty-five years of age and older residing in the United States... - Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family RegistryJenny N Poynter
Department of Preventive Medicine, University of Southern California, 1441 Eastlake Avenue, NOR4411A, Los Angeles, CA 90089 9175, USA
Cancer Res 67:11128-32. 2007..These data suggest that common variants may play important roles in the risk of CRC... - Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trialsHeike A Bischoff-Ferrari
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 86:1780-90. 2007..The role of total calcium intake in the prevention of hip fracture risk has not been well established... - Physical activity and survival after diagnosis of invasive breast cancerCrystal N Holick
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Cancer Epidemiol Biomarkers Prev 17:379-86. 2008..This study provides support for reduced overall mortality and mortality from breast cancer among women who engage in physical activity after breast cancer diagnosis... - Prediagnostic use of hormone therapy and mortality after breast cancerPolly A Newcomb
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Cancer Epidemiol Biomarkers Prev 17:864-71. 2008..Due to the high prevalence of past and current hormone use, it is important to investigate whether these preparations are related to breast cancer mortality... - Dietary calcium and vitamin D intake and risk of colorectal cancer: a prospective cohort study in womenPaul Terry
Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden
Nutr Cancer 43:39-46. 2002..Vitamin D intake was not clearly associated with risk. In sum, our data suggest that high calcium intake may lower colorectal cancer risk... - Effect of calcium supplementation on fracture risk: a double-blind randomized controlled trialHeike A Bischoff-Ferrari
Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Zurich, Switzerland
Am J Clin Nutr 87:1945-51. 2008..The effect of supplementation with calcium alone on risk fractures in a healthy population is not clear... - Early life risk factors in cancer: the relation of birth weight to adult obesityNicole M Leong
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Int J Cancer 103:789-91. 2003..76). These data suggest that both low and high birth weights are associated with higher adult BMI and support the hypothesis that fetal experience may influence adult obesity with potential consequences for risk of several major cancers... - MTHFR genotype and colorectal adenoma recurrence: data from a double-blind placebo-controlled clinical trialA Joan Levine
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Cancer Epidemiol Biomarkers Prev 17:2409-15. 2008..Our findings indicate that the MTHFR genotype does not change adenoma risk in a manner similar to its effect on colorectal cancer, and does not modify the effect of folate supplementation on metachronous adenoma risk... - Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer riskVirginia G Kaklamani
Cancer Genetics Program, Division of Hematology and Oncology, Department of Medicine and Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
JAMA 300:1523-31. 2008..While there is evidence of an association between circulating adiponectin levels and colorectal cancer risk, no association between genes of the adiponectin pathway and colorectal cancer have been reported to date... - Folate and colo-rectal cancer riskPeter Sanderson
Nutrition Division, Food Standards Agency, London WC2 6NH, UK
Br J Nutr 98:1299-304. 2007..Also, the need to study further the influence of genetically defined subgroups was highlighted for future research... - Accuracy of colorectal polyp self-reports: findings from the colon cancer family registryLisa Madlensky
Moores UCSD Cancer Center, 3855 Health Sciences Drive, MC0901, La Jolla, CA 92093 0901, USA
Cancer Epidemiol Biomarkers Prev 16:1898-901. 2007..However, it is not known how accurately patients are able to self-report the presence or absence of adenomas following colonoscopy... - Proton pump inhibitor use and risk of colorectal cancer: a population-based, case-control studyDouglas J Robertson
VA Medical Center, White River Junction, VT 05009, USA
Gastroenterology 133:755-60. 2007.... - Early failures of total hip replacement: effect of surgeon volumeElena Losina
Department of Biostatistics, Boston University School of Public Health and Robert B Brigham Arthritis and Musculoskeletal Clinical Research Center, Boston, Massachusetts 02118, USA
Arthritis Rheum 50:1338-43. 2004..To determine whether provider volume is associated with early failures following total hip replacement (THR) requiring revision... - What now for aspirin and cancer prevention?John A Baron
J Natl Cancer Inst 96:4-5. 2004 - Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trialRobert S Bresalier
Department of Gastrointestinal Medicine and Nutrition, University of Texas M D Anderson Cancer Center, Houston 77030 4009, USA
N Engl J Med 352:1092-102. 2005.... - Reported use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors was not associated with reduced recurrence of colorectal adenomasJeffrey T Wei
Division of Gastroenterology and Hepatology, University of North Carolina, Campus Box 7080, Chapel Hill, NC 27599, USA
Cancer Epidemiol Biomarkers Prev 14:1026-7. 2005..Lack of statistical power from limited exposure to HMG-CoA reductase inhibitors might be responsible for the lack of association... - Epidemiology of total knee replacement in the United States Medicare populationNizar N Mahomed
Musculoskeletal Health and Arthritis Program, Toronto Western Hospital, University Health Network, 399 Bathurst Street, University of Toronto, Toronto, Ontario M5T 2S8, Canada
J Bone Joint Surg Am 87:1222-8. 2005..In the United States, blacks and individuals with low income undergo total knee replacement less frequently and generally have higher rates of adverse outcomes following primary knee replacement... - Survival after hip fractureBahman Y Farahmand
Institute of Environmental Medicine, Karolinska Institute, Box 210, 17177, Stockholm, Sweden
Osteoporos Int 16:1583-90. 2005..Hip fracture patients have a substantially increased risk of death that persists for at least 6 years post-fracture. The relative excess mortality is independent of comorbidity and known hip fracture risk factors... - Fever of unknown origin and cancer: a population-based studyHenrik Toft Sørensen
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
Lancet Oncol 6:851-5. 2005..We aimed to assess the risk of cancer and survival after hospital admission for fever of unknown origin in a nationwide Danish follow-up study... - (Nutritional) chemoprevention of cancer: what's up?John A Baron
J Natl Cancer Inst 98:945-6. 2006 - Peptic ulcer and bleeding events associated with rofecoxib in a 3-year colorectal adenoma chemoprevention trialAngel Lanas
Department of Medicine, University Clinic Hospital, Instituto Aragones de Ciencias de la Salud CIBER HEPAD Zaragoza, Spain
Gastroenterology 132:490-7. 2007.... - Postmenopausal hormone therapy and risk of breast cancer by histologic type (United States)Laura M Newcomer
Program in Epidemiology, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA
Cancer Causes Control 14:225-33. 2003..Of particular interest is the association between combined hormone therapy and increased risk of lobular carcinoma. This lesion is increasingly common but, nonetheless, comprises fewer than 10% of invasive breast cancers... - Cholecystectomy and the risk of recurrent colorectal adenomasLisa C Vinikoor
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7555, USA
Cancer Epidemiol Biomarkers Prev 16:1523-5. 2007..34; 95% CI, 0.97-1.85) but the 95% CIs included the null in both cases. We conclude that the increased risk for colorectal cancer following cholecystectomy seems to be due to a biological process occurring after the adenoma has developed... - Can aspirin keep mortality at bay?John A Baron
Arch Intern Med 167:535-6. 2007 - Aspirin may be more effective in preventing colorectal adenomas in patients with higher BMI (United States)Sangmi Kim
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599-7555, USA
Cancer Causes Control 17:1299-304. 2006..The more pronounced effect of 325 mg aspirin in individuals with higher BMI suggests a possible protective role of anti-inflammatory aspirin against increased adipose-driven cytokines among obese subjects... - Neighborhoods matter: use of hospitals with worse outcomes following total knee replacement by patients from vulnerable populationsElena Losina
Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
Arch Intern Med 167:182-7. 2007.... - Skin cancers and non-hodgkin lymphoma among users of systemic glucocorticoids: a population-based cohort studyHenrik Toft Sørensen
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
J Natl Cancer Inst 96:709-11. 2004..68, 95% CI = 1.16 to 5.29). Our data suggest that use of glucocorticoids may be a shared risk factor for certain skin cancers and lymphomas... - Postmenopausal hormone replacement therapy and risk of acute pancreatitis: a population-based case-control studyMette S Tetsche
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
Am J Gastroenterol 102:275-8. 2007..To examine whether acute pancreatitis is associated with the use of postmenopausal hormonal replacement therapy in Danish women over 45 yr of age... - The age-at-diagnosis fallacyJohn A Baron
Arch Intern Med 166:1670; author reply 1671. 2006 - Incidence rates of dislocation, pulmonary embolism, and deep infection during the first six months after elective total hip replacementCharlotte B Phillips
Robert Breck Brigham Multipurpose Arthritis and Musculoskeletal Diseases Center, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA
J Bone Joint Surg Am 85:20-6. 2003..LEVEL OF EVIDENCE: Prognostic study, Level II-1 (retrospective study). See p. 2 for complete description of levels of evidence... - Re: Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriersJohn L Hopper
J Natl Cancer Inst 95:1010-1; author reply 1012-3. 2003 - Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort studyHenrik Toft Sørensen
Department of Clinical Epidemiology, Aarhus University Hospital, 8000 Aarhus C, Denmark
Lancet 370:1773-9. 2007..Other studies, however, do not show this association. To help clarify these discrepant findings, we aimed to investigate the risk of arterial cardiovascular events in patients who were diagnosed with venous thromboembolism...
Research Grants
- ASPIRIN/FOLATE PREVENTION OF LARGE BOWEL POLYPSJohn Baron; Fiscal Year: 2007....
- Colorectal Chemoprevention with Calcium and Vitamin DJohn Baron; Fiscal Year: 2007..abstract_text> ..
- Colorectal Chemoprevention with Calcium and Vitamin DJohn Baron; Fiscal Year: 2009..g. osteoporosis). We now request funds to complete the planned treatment and follow-up for all 2,200 randomized subjects, prepare for the first efficacy analyses, and implement a post-treatment follow-up. ..
- Colorectal Chemoprevention with Calcium and Vitamin DJohn Baron; Fiscal Year: 2009..In the study proposed here, we will evaluate the ability of supplemental vitamin D to reduce the risk of developing those infectious disorders. ..
- Colorectal Chemoprevention with Calcium and Vitamin DJOHN ANTHONY BARON; Fiscal Year: 2010..g. osteoporosis). We now request funds to complete the planned treatment and follow-up for all 2,200 randomized subjects, prepare for the first efficacy analyses, and implement a post-treatment follow-up. ..
- ASPIRIN/FOLATE PREVENTION OF LARGE BOWEL POLYPSJOHN ANTHONY BARON; Fiscal Year: 2010....
- ASPIRIN/FOLATE PREVENTION OF LARGE BOWEL POLYPSJohn Baron; Fiscal Year: 1999..We also propose to measure urinary thromboxane B2, and red blood cell and serum folate near the time of study completion. These will be used as measures of compliance with study agents. ..
- ASPIRIN PREVENTION OF LARGE BOWEL POLYPSJohn Baron; Fiscal Year: 1993..The study will also help elucidate the biology of large bowel carcinogenesis by defining the impact of a prostaglandin synthetase inhibitor on the occurrence of neoplastic polyps...