Victor Ambros

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. pmc Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    Lorenzo F Sempere
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Genome Biol 5:R13. 2004
  2. ncbi request reprint Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    Lorenzo F Sempere
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Dev Biol 259:9-18. 2003
  3. pmc Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis
    Nicholas S Sokol
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Genes Dev 22:1591-6. 2008
  4. ncbi request reprint Developmental biology. Encountering microRNAs in cell fate signaling
    Xantha Karp
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Science 310:1288-9. 2005
  5. pmc Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth
    Nicholas S Sokol
    Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Genes Dev 19:2343-54. 2005
  6. ncbi request reprint Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning
    Victor Ambros
    Department of Genetics, Dartmouth Medical School, Hanover, NH, USA
    Methods Mol Biol 265:131-58. 2004
  7. ncbi request reprint The regulation of genes and genomes by small RNAs
    Victor Ambros
    Dartmouth Medical School, Hanover, NH 03755, USA
    Development 134:1635-41. 2007
  8. ncbi request reprint MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing
    Victor Ambros
    Dartmouth Medical School, Department of Genetics, Hanover, NH 03755, USA
    Cell 113:673-6. 2003
  9. ncbi request reprint The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    Allison L Abbott
    Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Dev Cell 9:403-14. 2005
  10. pmc The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding
    Marta Hristova
    Dartmouth Medical School, Department of Genetics, Hanover, NH 03755, USA
    Mol Cell Biol 25:11059-72. 2005

Detail Information

Publications15

  1. pmc Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    Lorenzo F Sempere
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Genome Biol 5:R13. 2004
    ..lin-4, let-7 and other miRNA genes are conserved in mammals, and their potential functions in mammalian development are under active study...
  2. ncbi request reprint Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    Lorenzo F Sempere
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Dev Biol 259:9-18. 2003
    ....
  3. pmc Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis
    Nicholas S Sokol
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Genes Dev 22:1591-6. 2008
    ..This heterochronic role of let-7 is likely just one of the ways in which let-7-C promotes adult behavior...
  4. ncbi request reprint Developmental biology. Encountering microRNAs in cell fate signaling
    Xantha Karp
    Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA
    Science 310:1288-9. 2005
  5. pmc Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth
    Nicholas S Sokol
    Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Genes Dev 19:2343-54. 2005
    ..Thus, DmiR-1 is not required for the formation or physiological function of the larval musculature, but is required for the dramatic post-mitotic growth of larval muscle...
  6. ncbi request reprint Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning
    Victor Ambros
    Department of Genetics, Dartmouth Medical School, Hanover, NH, USA
    Methods Mol Biol 265:131-58. 2004
    ..Northern blot hybridization is used to confirm the expression of small RNAs in vivo...
  7. ncbi request reprint The regulation of genes and genomes by small RNAs
    Victor Ambros
    Dartmouth Medical School, Hanover, NH 03755, USA
    Development 134:1635-41. 2007
    ....
  8. ncbi request reprint MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing
    Victor Ambros
    Dartmouth Medical School, Department of Genetics, Hanover, NH 03755, USA
    Cell 113:673-6. 2003
    ..In C. elegans, a homolog of the well-known fly developmental regulator hunchback acts downstream of the microRNAs lin-4 and let-7 in a pathway controlling developmental timing...
  9. ncbi request reprint The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
    Allison L Abbott
    Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    Dev Cell 9:403-14. 2005
    ..These results indicate that let-7 family microRNAs function in combination to affect both early and late developmental timing decisions...
  10. pmc The Caenorhabditis elegans heterochronic regulator LIN-14 is a novel transcription factor that controls the developmental timing of transcription from the insulin/insulin-like growth factor gene ins-33 by direct DNA binding
    Marta Hristova
    Dartmouth Medical School, Department of Genetics, Hanover, NH 03755, USA
    Mol Cell Biol 25:11059-72. 2005
    ..These results reinforce the conclusion that lin-14 encodes a novel class of transcription factor...
  11. pmc Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans
    Rosalind C Lee
    Dartmouth Medical School, Department of Genetics, Hanover, New Hamphsire 03755, USA
    RNA 12:589-97. 2006
    ..elegans. Microarray expression profiling of RNAi-defective mutant worms further suggests diverse endogenous RNAi pathways for silencing different sets of genes...
  12. ncbi request reprint MicroRNAs and other tiny endogenous RNAs in C. elegans
    Victor Ambros
    Dartmouth Medical School, Department of Genetics, Hanover, NH 03755, USA
    Curr Biol 13:807-18. 2003
    ..We employed cDNA sequencing and comparative genomics to identify additional C. elegans small RNAs with properties similar to miRNAs and siRNAs...
  13. ncbi request reprint The functions of animal microRNAs
    Victor Ambros
    Dartmouth Medical School, Department of Genetics, Hanover, New Hampshire 03755, USA E mail
    Nature 431:350-5. 2004
    ....
  14. pmc A uniform system for microRNA annotation
    Victor Ambros
    Dartmouth Medical School Department of Genetics, Hanover, New Hampshire 03755, USA
    RNA 9:277-9. 2003
    ..Finally, an online clearinghouse for miRNA gene name assignments is provided by the Rfam database of RNA families...
  15. ncbi request reprint The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster
    Lorenzo F Sempere
    Department of Genetics, Dartmouth College, Hanover, New Hampshire 03755, USA
    Dev Biol 244:170-9. 2002
    ..These results demonstrate an interaction between steroid hormone signaling and the heterochronic pathway in insects...