Research Topics
| C Fordham von ReynSummaryAffiliation: Dartmouth-Hitchcock Medical Center Country: USA Publications
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Detail Information
Publications
Fish tank exposure and cutaneous infections due to Mycobacterium marinum: tuberculin skin testing, treatment, and preventionFelicia M T Lewis
Infectious Disease Section, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Clin Infect Dis 37:390-7. 2003..Positive tuberculin reactions may be due to infection with M. marinum. Persons with open skin lesions or immunosuppression should avoid cutaneous contact with fish tanks...
Prevention of tuberculosis in Bacille Calmette-Guérin-primed, HIV-infected adults boosted with an inactivated whole-cell mycobacterial vaccineCharles F von Reyn
Infectious Disease and International Health, Dartmouth Medical School, Hanover, New Hampshire, USA
AIDS 24:675-85. 2010..To determine whether a multiple-dose series of an inactivated whole cell mycobacterial vaccine, Mycobacterium vaccae, can prevent HIV-associated tuberculosis...
Basis for treatment of tuberculosis among HIV-infected patients in Tanzania: the role of chest x-ray and sputum cultureMuhammad Bakari
Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
BMC Infect Dis 8:32. 2008..We sought to determine the role of chest x-ray and sputum culture in the decision to treat for presumptive TB using active case finding in a large cohort of HIV-infected patients...
Immunogenicity of a protective whole cell mycobacterial vaccine in HIV-infected adults: a phase III study in TanzaniaTimothy Lahey
Dartmouth Medical School, Lebanon, NH 03756, USA
Vaccine 28:7652-8. 2010..Post-immunization immune responses to MV correlated with baseline clinical factors, but the responses did not predict protection from HIV-associated TB...
Interferon γ responses to mycobacterial antigens protect against subsequent HIV-associated tuberculosisTimothy Lahey
Dartmouth Medical School, Lebanon, New Hampshire, USA
J Infect Dis 202:1265-72. 2010..The cellular immune responses that protect against tuberculosis have not been identified...
Polyantigenic interferon-γ responses are associated with protection from TB among HIV-infected adults with childhood BCG immunizationTimothy Lahey
Dartmouth Medical School, Lebanon, New Hampshire, United States of America
PLoS ONE 6:e22074. 2011..Surrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified...
Molecular epidemiology of HIV-associated tuberculosis in Dar es Salaam, Tanzania: strain predominance, clustering, and polyclonal diseaseLisa V Adams
Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA
J Clin Microbiol 50:2645-50. 2012..Polyclonal infection was detected and isolates representing the East Indian GD strain family were the most common...
Lymphocyte proliferation to mycobacterial antigens is detectable across a spectrum of HIV-associated tuberculosisTimothy Lahey
Dartmouth Medical School, Lebanon, NH, USA
BMC Infect Dis 9:21. 2009..Identifying novel TB diagnostics is a major public health priority. We explored the diagnostic characteristics of antimycobacterial lymphocyte proliferation assays (LPA) in HIV-infected subjects with latent or active TB...
Recurrent tuberculosis risk among HIV-infected adults in Tanzania with prior active tuberculosisTimothy Lahey
Geisel School of Medicine at Dartmouth, Lebanon, NH 03756, USA
Clin Infect Dis 56:151-8. 2013..Active tuberculosis is common among human immunodeficiency virus (HIV)-infected persons living in tuberculosis-endemic areas, but the hazard of subsequent tuberculosis disease has not been quantified in a single prospective cohort...
Utility of dual skin tests to evaluate tuberculin skin test reactions of 10 to 14 mm in healthcare workersBryan J Marsh
Infectious Disease Section, Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Infect Control Hosp Epidemiol 24:821-4. 2003..CONCLUSION: A reaction of 10 to 14 mm to PPD should not be used as an indication for the treatment of latent tuberculosis (TB) infection in healthy HCWs born in the United States with no known exposure to TB...
Maintenance of Sensitivity of the T-SPOT.TB Assay after Overnight Storage of Blood Samples, Dar es Salaam, TanzaniaElizabeth A Talbot
Dartmouth Medical School, Hanover, NH 03755, USA
Tuberc Res Treat 2012:345290. 2012..8% (95%CI; 88.8-99.6%). Conclusions. When T Cell Xtend reagent is added to specimens held overnight at recommended temperatures, T-SPOT.TB is as sensitive as the standard assay in patients with tuberculosis...
T-SPOT.TB Test(R) results in adults with Mycobacterium avium complex pulmonary diseaseLisa V Adams
Section of Infectious Disease and International Health, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
Scand J Infect Dis 40:196-203. 2008..Reactions to the T-SPOT.TB Test may persist months to years after treatment of tuberculosis...
Increased mortality in rural patients with HIV in New EnglandTimothy Lahey
Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
AIDS Res Hum Retroviruses 23:693-8. 2007..11, 1.064 to 4.218, p = 0.047). Patients with HIV who live in rural areas have higher mortality rates than urban patients with HIV...
Recent trends in infective endocarditis: influence of case definitionsRoni K Devlin
Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Curr Opin Cardiol 19:134-9. 2004..SUMMARY: Recent trends in diagnosis, microbiology, and treatment of infective endocarditis are described, and case definitions play a critical role in their interpretation...
Clinical and epidemiological correlates of genotypes within the Mycobacterium avium complex defined by restriction and sequence analysis of hsp65Sandra C Smole
Department of Medicine, Boston University School of Medicine, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
J Clin Microbiol 40:3374-80. 2002....
New vaccines for the prevention of tuberculosisC Fordham von Reyn
Infectious Disease Section, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
Clin Infect Dis 35:465-74. 2002..Because there is no identified surrogate marker for protection, identification of an improved vaccine will require long-term efficacy trials in humans...
