J M Lappe

..However, the in vivo significance of B cells in human bone metabolism and osteoporosis is still largely unknown, particularly at the systematic gene expression level...

..This study examined the effects of synthetic genistein in combination with other potential bone-protective dietary molecules on bone mineral density (BMD) in early postmenopausal women...

..It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices of obesity and body composition...

..Numerous observational studies have found supplemental calcium and vitamin D to be associated with reduced risk of common cancers. However, interventional studies to test this effect are lacking...

..Inadequate vitamin D nutritional status is increasingly recognized as common in North American and European populations, but the extent of the shortfall and the parameters of the distribution for populations of interest remain uncertain...

..Our findings that QUS values change during childhood and adolescence in a manner similar to DXA values, the "gold standard," provide support for the validity of using QUS to assess bone health in children and adolescents...

..QUS predicted stress fracture in female recruits as well as it predicts hip fracture in elderly women. Recruits with low QUS values and a history of smoking and not exercising had an extremely high risk of stress fracture...

..To determine whether pubertal girls assigned to calcium-rich diets or their usual calcium intakes differ significantly in weight gain...

..CONCLUSIONS: The long-term, total body weight trajectory at mid-life is not influenced appreciably by either cessation of ovarian function or by hormone replacement...

....

..Ac.f nearly doubled 1 year after menopause, tripled 13 years after menopause, and remained elevated in women with osteoporosis...

..The study was designed to capture true longitudinal transmenopausal changes in three-dimensional (3-D) trabecular bone architecture. Currently, minimal data exist regarding these features...

..An understanding of the material presented here will provide a foundation to assess the bone health of individuals, to promote bone health, and to prevent fracture in patients of all ages...

..The purpose of this article is to present a synthesis of information comparing HRT and SERMs so that the reader can help his/her clients make informed choices about replacement therapy...

..Correlations were weak to moderate between parameters measured on biopsies and scans...

..The goal of this randomized double-blind, placebo-controlled study was to determine whether a calcium and vitamin D intervention could reduce the incidence of SFx in female recruits during basic training...

..Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits...

..Previous studies examining the reliability of self-reported Tanner stages have given conflicting results. We report on the reliability of self-reported Tanner stages in lean healthy children...

..The results may contribute to identification of new genes and their functions for osteoporosis and suggest genetic markers to discern individuals at higher risk to osteoporosis with an aim for preventive intervention and treatment...

..Negative findings would provide support for further research into other methods of concomitant methods of maximizing skeletal development. ..

..If these findings hold, they would provide strong support for the essential role of calcium in addition to exercise in maximizing bone mass in growing females. ..

..Lack of a calcium effect would provide support for further research into other methods or concomitant methods of maximizing skeletal development. ..

..Positive findings will provide support for health policy changes to promote optimal vitamin D levels in the population. ..

..Such a dairy intervention would be congruent with currently recommended calcium and dairy intake. ..

..It specifically addresses Strategic Objective 2, to "accelerate progress in cancer prevention." Positive findings from our proposed nutritional intervention study will result in an inexpensive, safe method of preventing cancer. ..

..Such a dairy intervention would be congruent with currently recommended calcium and dairy intake. ..

..The genetic factors identified from this revision are important for understanding the mechanisms accounting for population variation in prevalent vitamin D status, and for individualizing dosing with vitamin D supplementation. ..

..I.'s work is to test interventions designed to bring about conscious increases in calcium intake and physical activity in children to improve their bone health and develop lifelong bone healthy behaviors. ..

..Negative findings would provide support for further research into other methods of concomitant methods of maximizing skeletal development. ..

..This is a valid method to determine compliance, far superior to the traditional pill counts, and thus a substantial aid to measure the anti-fracture efficacy of calcium alone or calcium plus vitamin D interventions. ..

..It specifically addresses Strategic Objective 2, to "accelerate progress in cancer prevention." Positive findings from our proposed nutritional intervention study will result in an inexpensive, safe method of preventing cancer. ..