Research Topics
| Gordon GongSummaryAffiliation: Creighton University Country: USA Publications
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Detail Information
Publications
Fine mapping of susceptibility genes by Lewontin's linkage disequilibrium measure with application to Alzheimer's diseaseGordon Gong
Creighton University Osteoporosis Research Center, 601 North 30th Street, Suite 6730, Omaha, NE 68131, USA
Chin Med J (Engl) 115:1233-40. 2002..To formulate an equation for fine mapping of disease loci under complex conditions and determine the marker-disease distance in a specific case using this equation...
Association between bone mineral density and candidate genes in different ethnic populations and its implicationsG Gong
Creighton University Osteoporosis Research Center, 601 North 30th Street, Suite 6730, Omaha, NE 68131, USA
Calcif Tissue Int 72:113-23. 2003..Phenotype-genotype associations found in East Asians are unlikely to be due to admixture with Caucasians...
Genetic dissection of myocilin glaucomaGordon Gong
Osteoporosis Research Center, Creighton University Omaha, NE 68131, USA
Hum Mol Genet 13:R91-102. 2004..Polymorphisms at several loci including MYOC are associated with POAG, and play an important role in the pathogenesis of POAG...
Race, ethnicity and prevalence of primary open-angle glaucomaOmofolasade Kosoko-Lasaki
Department of Surgery, Creighton University, Omaha, NE 68178, USA
J Natl Med Assoc 98:1626-9. 2006..Recently, some authors pooled data from studies on the Dutch, Australians and Americans of European origin in an attempt to predict the prevalence of primary open-angle glaucoma (POAG) in the United States...
American founder mutation for Lynch syndrome. Prevalence estimates and implicationsHenry T Lynch
Department of Preventive Medicine and Public Health, Creighton University, Omaha, Nebraska 68178, USA
Cancer 106:448-52. 2006..This test might serve as first-line screening for Lynch syndrome mutations, provided AFM was prevalent, which is assessed in the current study...
Patient responses to the disclosure of BRCA mutation tests in hereditary breast-ovarian cancer familiesHenry T Lynch
Department of Preventive Medicine and Public Health, Creighton University, 2500 California Plaza, Omaha, Nebraska 68178, USA
Cancer Genet Cytogenet 165:91-7. 2006..Despite these psychological consequences, carriers and noncarriers reported a positive attitude toward genetic testing...
Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implicationsHenry T Lynch
Department of Preventive Medicine, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA
Eur J Hum Genet 14:390-402. 2006....
Family information service participation increases the rates of mutation testing among members of families with BRCA1/2 mutationsHenry T Lynch
Department of Preventive Medicine, Creighton University School of Medicine, Omaha, Nebraska 68178, USA
Breast J 15:S20-4. 2009..FIS attendance significantly increased the rate of mutation testing among high-risk family members...
Origins and prevalence of the American Founder Mutation of MSH2Mark Clendenning
Human Cancer Genetics Program, The Ohio State University, Columbus, Ohio 43210, USA
Cancer Res 68:2145-53. 2008..The consequences of this finding would be that the AFM is significantly more frequent in the United States than was previously predicted...
Inherited, familial and sporadic primary open-angle glaucomaGordon Gong
West Texas EXPORT Center, F Marie Hall Institute for Rural and Community Health, Texas Tech University Health Science Center, Lubbock, TX 79409 USA
J Natl Med Assoc 99:559-63. 2007..The suggested classification of POAG may serve as a useful guide in clinical practice and genetic studies where ethnic background and familial aggregation must be taken into consideration...
Bone mineral density-affecting genes in AfricansGordon Gong
Center, University of Texas at Houston, Houston, TX, USA
J Natl Med Assoc 98:1102-8. 2006..We have recently reported the role of environmental exposure in the ethnic diversity of bone mineral density (BMD). Potential genetic difference has not been adequately assessed...
Bone mineral density of recent African immigrants in the United StatesGordon Gong
West Texas EXPORT Center, Office of Rural and Community Health, Texas Tech University Health Science Center, Box 45013 STOP 5013, Lubbock, TX 79409, USA
J Natl Med Assoc 98:746-52. 2006..Racial/ethnic difference in bone mineral density (BMD) exists. The underlying mechanism is unclear and needs investigation...
The I1307K APC polymorphism in Ashkenazi Jews with colorectal cancer: clinical and pathologic featuresGershon Y Locker
Evanston Northwestern Healthcare, Feinberg School of Medicine, Northwestern University, 2650 Ridge Ave, Evanston, IL 60201, USA
Cancer Genet Cytogenet 169:33-8. 2006..We could find no group of Ashkenazi Jews with colorectal cancer for whom screening for I1307K would be clinically useful...
Factors associated with undiagnosed open-angle glaucoma: the Thessaloniki Eye StudyFotis Topouzis
II Department of Ophthalmology, Aristotle University of Thessaloniki, General Hospital Papageorgiou, Periferiaki Odos Thessalonikis N Efkarpia 56403, Thessaloniki, Greece
Am J Ophthalmol 145:327-335. 2008..To identify factors associated with undiagnosed open-angle glaucoma (OAG), primary open-angle glaucoma (POAG), and pseudoexfoliative glaucoma (PEXG) in an elderly population in Thessaloniki, Greece...
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass traitRandall D Little
Department of Human Genetics, Genome Therapeutics Corporation, Waltham, MA 02453, USA
Am J Hum Genet 70:11-9. 2002..Our findings suggest that the HBM mutation confers a unique osteogenic activity in bone remodeling, and this understanding may facilitate the development of novel therapies for the treatment of osteoporosis...
