Research Topics
| Zoran GatalicaSummaryAffiliation: Creighton University Country: USA Publications
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Detail Information
Publications
Syk tyrosine kinase expression during multistep mammary carcinogenesisZoran Gatalica
Creighton University Medical Center, 601 North 30th Street, Omaha, NE 68131, USA
Croat Med J 46:372-6. 2005..To analyze the expression of Syk tyrosine kinase, recently implicated as a tumor suppressor in mammary carcinogenesis, during the multi step development of human breast carcinoma...
Activation of the hedgehog pathway in advanced prostate cancerTao Sheng
Sealy Centers for Cancer Cell Biology and Environmental Health, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555 1048, USA
Mol Cancer 3:29. 2004..Prostate cancer is the second most prevalent cause of cancer death in American men. Therefore, identification of novel therapeutic targets for prostate cancer has significant clinical implications...- Gene expression profile of an adenomyoepithelioma of the breast with a reciprocal translocation involving chromosomes 8 and 16Zoran Gatalica
Department of Pathology, Creighton University School of Medicine, 601 North 30th Street, Omaha, NE 68131 2197
Cancer Genet Cytogenet 156:14-22. 2005.... 
ER-α36, a novel isoform of ER-α66, is commonly over-expressed in apocrine and adenoid cystic carcinomas of the breastSemir Vranic
Department of Pathology, Creighton University Medical Center, Omaha, Nebraska, USA
J Clin Pathol 64:54-7. 2011..ER-α36 primarily localises to the cytoplasm and the plasma membrane, and responds to membrane-initiated oestrogen and antioestrogen signalling pathways...- Detection of chromosomal aberrations in renal tumors: a comparative study of conventional cytogenetics and virtual karyotyping with single-nucleotide polymorphism microarraysFederico A Monzon
Department of Pathology, The Methodist Hospital Research Institute, The Methodist Hospital, Houston, Texas 77030, USA
Arch Pathol Lab Med 133:1917-22. 2009.... - Low grade peritoneal mucinous carcinomatosis associated with human papilloma virus infection: case reportZoran Gatalica
Department of Pathology, Creighton University Medical Center, 601 N 30th St, Omaha, NE 68131, USA
Croat Med J 49:669-73. 2008..To the best of our knowledge, this is the first description of HPV-associated malignancy presenting as pseudomyxoma peritonei... - EGFR and HER-2/neu expression in invasive apocrine carcinoma of the breastSemir Vranic
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA
Mod Pathol 23:644-53. 2010..Pure apocrine carcinomas show consistent overexpression of either EGFR or HER-2/neu, which could have significant therapeutic implications... - Clinical implications of novel activating EGFR mutations in malignant peritoneal mesotheliomaJason M Foster
Department of Surgery, Creighton Cancer Center, Creighton University, Omaha, NE, USA
World J Surg Oncol 8:88. 2010..Here we present the mutant EGFR activating potential and the matured survival data of the EGFR mutant(mut+) relative to wild type EGFR(mut-) mesothelioma... - Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growthDennis W Wolff
Department of Pharmacology, Creighton University School of Medicine, Omaha, NE 68178, USA
Int J Cancer 130:1521-31. 2012..Targeting this reversible process may provide a new strategy for suppressing prostate cancer progression by reestablishing its androgen sensitivity... - Right hemicolectomy is not routinely indicated in pseudomyxoma peritoneiJason M Foster
Department of Surgery, Creighton Cancer Center, Creighton University, Omaha, NE 68198 4030, USA
Am Surg 78:171-7. 2012..Performance status and complete cytoreduction are the only factors associated with survival. Lymph node involvement is rare and selective RHC is safe in PMP/MAN... - Renal medullary carcinomas: histopathologic phenotype associated with diverse genotypesZoran Gatalica
Department of Pathology, Creighton University School of Medicine, Omaha, NE 68131, USA
Hum Pathol 42:1979-88. 2011.... - Novel intronic germline FLCN gene mutation in a patient with multiple ipsilateral renal neoplasmsZoran Gatalica
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA
Hum Pathol 40:1813-9. 2009..In addition, chromosomal analysis of peripheral blood lymphocytes showed low level chromosome instability, not previously associated with germline mutations in the FLCN gene... - Molecular events in the progression of recurrent respiratory papillomatosis to carcinomaSubodh M Lele
Department of Pathology, University of Kentucky College of Medicine, Lexington 40536, USA
Arch Pathol Lab Med 126:1184-8. 2002.... - Detection of High-Risk HPV in Head and Neck Squamous Cell Carcinomas: Comparison of Chromogenic In Situ Hybridization and a Reverse Line Blot MethodTodd M Stevens
Department of Pathology, Creighton University Medical Center, Omaha, NE Molecular Genetic Pathology Laboratory, Yellowstone Pathology Institute, Inc, Billings, MT Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Appl Immunohistochem Mol Morphol 19:574-8. 2011..003). ISH offers the advantage of visual cell-type localization of viral infection but overall it is less sensitive than the polymerase chain reaction-based detection of HPV in HNSCC... - Neuroendocrine-type prostatic adenocarcinoma with microsatellite instability in a patient with lynch syndromeDavid G Wagner
University of Nebraska Medical Center, Omaha, NE, USA
Int J Surg Pathol 18:550-3. 2010..These findings suggest that HGPIN-NE is a precursor of invasive SCC and also that prostatic SCC can develop in a patient with the Lynch syndrome... - Clinical genomics of renal epithelial tumorsJill M Hagenkord
Department of Pathology, Creighton University School of Medicine, Omaha, NE, USA
Cancer Genet 204:285-97. 2011..This review summarizes the genetic and genomic changes in the most common types of renal epithelial tumors and highlights the clinical implications of these aberrations... 
Assessment of HER2 gene status in breast carcinomas with polysomy of chromosome 17Semir Vranic
Department of Pathology, Creighton University School of Medicine, Omaha, Nebraska 68131, USA
Cancer 117:48-53. 2011..2. These guidelines are potentially contradictory in tumors with polysomy of chromosome 17...- Intraosseous lipoma. A clinical, radiologic, and pathologic study of 5 casesEduardo Eyzaguirre
Division of Surgical Pathology, Department of Pathology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555 0588, USA
Ann Diagn Pathol 11:320-5. 2007..Intraosseous lipoma often contains calcified necrotic fat with little mature adipose tissue and characteristically induces expansion/remodeling of the affected bone... - Hereditary breast cancer: part II. Management of hereditary breast cancer: implications of molecular genetics and pathologyEdibaldo Silva
Surgical Oncology Department, Creighton University Medical Center Cancer Center, Omaha, Nebraska 68178, USA
Breast J 14:14-24. 2008.... - Novel and existing mutations in the tyrosine kinase domain of the epidermal growth factor receptor are predictors of optimal resectability in malignant peritoneal mesotheliomaJason M Foster
Division of Surgical Oncology, Creighton University Medical Center, Creighton University, Omaha, NE 68131, USA
Ann Surg Oncol 16:152-8. 2009..Experiments confirming the activating properties of the novel mutations are warranted... - Familial sarcoma: challenging pedigreesHenry T Lynch
Department of Preventive Medicine, Creighton University School of Medicine, Omaha, Nebraska 68178, USA
Cancer 98:1947-57. 2003.... - Monosomy 22 as a diagnostic aid in a case of late recurrence of adult granulosa cell tumor of the ovarySamuel K Caughron
Department of Pathology, Creighton University Medical Center, 601 North 30th Street, Omaha, NE 68131, USA
Cancer Genet Cytogenet 156:83-5. 2005..This anomaly, typical of granulosa cell tumor, coupled with the pathologic and immunophenotypic findings assisted in establishing the proper diagnosis of this lesion in the absence of the original histopathologic slides... - Renal smooth muscle hamartomaZoran Gatalica
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA
Pathol Res Pract 206:782-4. 2010..These findings are consistent with smooth muscle hamartoma, a rare benign renal tumor-like lesion... - Let-7 family miRNAs regulate estrogen receptor alpha signaling in estrogen receptor positive breast cancerYingchun Zhao
Genomics and Functional Proteomics Laboratories, Osteoporosis Research Center, Creighton University Medical Center, 601 N 30th St, Suite 6730, Omaha, NE 68131, USA
Breast Cancer Res Treat 127:69-80. 2011..In conclusion, our findings indicate a new regulatory mechanism of let-7 miRNAs in ER-α mediated cellular malignant growth of breast cancer... - FAP, gastric cancer, and genetic counseling featuring children and young adults: a family study and reviewHenry T Lynch
Department of Preventive Medicine and Public Health, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA
Fam Cancer 9:581-8. 2010.... - A (9;11)(q34;q13) translocation in a hibernomaKiran K Turaga
Department of Surgery, Creighton University Medical Center, Omaha, NE 68131, USA
Cancer Genet Cytogenet 170:163-6. 2006..Here, we present a case of a hibernoma with a novel cytogenetic alteration involving a reciprocal translocation between 9q and 11q that was useful in establishing the final diagnosis... - Imbalances of chromosomes 4, 9, and 12 are recurrent in the thecoma-fibroma group of ovarian stromal tumorsRenae C Streblow
Departments of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198 3135, USA
Cancer Genet Cytogenet 178:135-40. 2007..In contrast, loss of chromosomes 4 and/or 9 are recurrent in fibroma. In summary, imbalances of chromosomes 4 and 9 appear to represent important secondary abnormalities in the thecoma-fibroma ovarian tumor group... - Monoallelic deletion of the p53 gene through chromosomal translocation in a small cell osteosarcomaJun Nishio
Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198-3135, USA
Virchows Arch 448:852-6. 2006.... - COX-2 expression in pseudomyxoma peritoneiZoran Gatalica
Department of Pathology, Creighton University Medical Center, 601 N 30th Street, Omaha, NE 68131, USA
Cancer Lett 244:86-90. 2006..In addition, COX-2 was detected in stromal, endothelial, inflammatory cells and reactive mesothelium. This preliminary information indicates a potential for the use of COX-2 inhibitors in patients with PMP... - ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomasLisa M J Lee
Department of Pathology, Creighton University Medical School, Omaha, NE 68178, USA
Anticancer Res 28:479-83. 2008.... - Cervical and endometrial metastases of appendiceal goblet cell carcinoidZenggang Pan
Department of Pathology, Creighton University Medical Center, Omaha, Nebraska 68131, USA
Arch Pathol Lab Med 134:776-80. 2010..Therefore, for any uterine cervical/endometrial signet ring cell carcinoma, a metastatic appendiceal GCC should be considered in the differential diagnosis, especially after excluding other primary sites... - Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancerKristen M Drescher
Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178, USA
Fam Cancer 8:231-9. 2009.... - Pathology of the hereditary colorectal carcinomaZoran Gatalica
Department of Pathology, Creighton University Medical Center, Omaha, NE 68131, USA
Fam Cancer 7:15-26. 2008..The role of pathologist is to recognize these characteristics and initiate appropriate follow up with clinicians and genetic counselors... - COX-2 gene polymorphisms and protein expression in renomedullary interstitial cell tumorsZoran Gatalica
Department of Pathology, Creighton University Medical Center, Omaha, Nebraska 68131, USA
Hum Pathol 39:1495-504. 2008.... - A common 1317TC polymorphism in MTHFR can lead to erroneous 1298AC genotyping by PCR-RE and TaqMan probe assaysRichard A Allen
Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
Genet Test 11:167-73. 2007..It is hoped that laboratories offering MTHFR 1298AC testing are cognizant of some of the inherent problems in published methods... - Benign myoepithelial tumors of the breast have immunophenotypic characteristics similar to metaplastic matrix-producing and spindle cell carcinomasNikolay K Popnikolov
Division of Surgical Pathology, Department of Pathology, University of Texas Medical Branch, Galveston, USA
Am J Clin Pathol 120:161-7. 2003..The abnormal expression of oncogenes or antioncogenes, such as p53, may be more useful for distinguishing between those entities than the expression of the classic myoepithelial markers... - FISH for HER-2/neu in breast cancer: standardization makes the difference!Sumita Gokhale
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
Indian J Cancer 41:152-8. 2004..CONCLUSION: Based on these results, we consider FISH to be the gold standard for detecting HER-2/neu status in breast cancer... - Decreased expression of e6-associated protein in breast and prostate carcinomasXiuhua Gao
Cancer Center, Criss III, Room 352, Creighton University, 2500 California Plaza, Omaha, Nebraska 68178, USA
Endocrinology 146:1707-12. 2005.... - Genital human papillomavirus testing by in situ hybridization in liquid atypical cytologic materials and follow-up biopsiesC Bewtra
Department of Pathology, Creighton University Medical Center, Omaha, Nebraska 68131, USA
Acta Cytol 49:127-31. 2005..CONCLUSION: There is a small but significant (14%) false negative rate with HPV testing by the Ventana ISH method. Clinically suspicious cases should be followed even if an HPV test is negative... - Loss of mismatch repair proteins in sebaceous gland tumorsNikolay K Popnikolov
Department of Pathology, The University of Texas Medical Branch at Galveston, Texas, USA
J Cutan Pathol 30:178-84. 2003..This indicates the importance of the abnormal DNA mismatch repair in the progression of this disease... - Cytogenetic findings in a case of nodular fasciitis of subclavicular regionGopalrao V N Velagaleti
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
Cancer Genet Cytogenet 141:160-3. 2003..TRKC is implicated in congenital fibrosarcoma, a benign proliferation of fibroblasts. The breakpoint and overexpression of the protein in our case further suggest a possible involvement of TRKC... - PIK3CA and PTEN mutations in adenoid cystic carcinoma of the breast metastatic to kidneySemir Vranic
Department of Pathology, Clinical Center of University of Sarajevo, Sarajevo 71000, Bosnia and Herzegovina
Hum Pathol 38:1425-31. 2007..These coexistent mutations/epigenetic inactivations in PI3K/AKT pathway may be responsible for the unusually aggressive course of ACC... - Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (malignant triton tumor) with balanced t(7;9)(q11.2;p24) and unbalanced translocation der(16)t(1;16)(q23;q13)Gopalrao V N Velagaleti
Department of Pediatrics, The University of Texas Medical Branch, Children s Hospital, Suite 3 350, 301 University Boulevard, Galveston, TX 77555, USA
Cancer Genet Cytogenet 149:23-7. 2004..This finding may relate to the observed poor prognostic outcome in this type of sarcoma. Also unique to our case is the translocation involving 7q and 9p, both regions may play a role in MPNST... - Downregulation of TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L in Barrett's esophagus with dysplasia and adenocarcinomaNikolay K Popnikolov
Drexel University College of Medicine, Department of Pathology and Laboratory Medicine, Philadelphia, Pennsylvania, USA
Appl Immunohistochem Mol Morphol 14:161-5. 2006..Thus, the immunohistochemically detected downregulation of TRAIL expression appears to be a promising indicator of dysplasia in Barrett's esophagus... - Global expression profiles in human normal and aneurysmal abdominal aorta based on two distinct whole genome microarray platformsGuy M Lenk
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, 3317 Gordon H. Scott Hall of Basic Medical Sciences, 540 E. Canfield Ave, Detroit, MI 48201, USA
Ann N Y Acad Sci 1085:360-2. 2006.... - Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysmsGuy M Lenk
Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, USA
BMC Genomics 8:237. 2007....