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Genomes and Genes | Rhonda K YantissSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Use of IMP3 in identification of carcinoma in fine needle aspiration biopsies of pancreasRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 525 East 68th Street, New York, New York 10021, USA
Acta Cytol 52:133-8. 2008..To evaluate insulin-like growth factor-II mRNA binding protein 3 (IMP3), which is an oncofetal RNA-binding protein expressed in pancreatic carcinomas and detectable by immunohistochemistry, in diagnosis of pancreatic cancer...
A comprehensive study of nondysplastic and dysplastic serrated polyps of the vermiform appendixRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA
Am J Surg Pathol 31:1742-53. 2007..These features, including BRAF mutations, may be more closely related to a serrated morphology in appendiceal polyps rather than biologically important changes...
Filiform serrated adenomas: a clinicopathologic and immunophenotypic study of 18 casesRhonda K Yantiss
Weill Medical College of Cornell University, Department of Pathology, New York, NY 10021, USA
Am J Surg Pathol 31:1238-45. 2007..We conclude that filiform SA potentially represents an unusual variant of SA with a predilection for the left colon, particularly the rectum...
Clinical, pathologic, and molecular features of early-onset colorectal carcinomaRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA
Am J Surg Pathol 33:572-82. 2009..Posttranslational regulation of mRNA and subsequent protein expression may be particularly important to the development of colorectal carcinomas in young patients...
Optimal approach to obtaining mucosal biopsies for assessment of inflammatory disorders of the gastrointestinal tractRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
Am J Gastroenterol 104:774-83. 2009....
Prognostic significance of superficial fissuring ulceration in patients with severe "indeterminate" colitisRhonda K Yantiss
Department of Pathology, University of Massachusetts Medical School UMass Memorial Health Care, Worcester, MA, USA
Am J Surg Pathol 30:165-70. 2006..Nevertheless, the presence of superficial fissuring-type ulcers in patients with severe chronic active UC denotes a subgroup with a higher risk of pouchitis following surgical resection...
Diagnostic challenges in the pathologic evaluation of Barrett esophagusRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Arch Pathol Lab Med 134:1589-600. 2010..Recent data also indicate that specific molecular changes occur in nondysplastic Barrett mucosa and herald the development of dysplasia and/or carcinoma...
Prognostic significance of localized extra-appendiceal mucin deposition in appendiceal mucinous neoplasmsRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Am J Surg Pathol 33:248-55. 2009....
Histologic predictors of pouchitis in patients with chronic ulcerative colitisRhonda K Yantiss
Department of Pathology of the University of Massachusetts Medical School UMass Memorial Health Care, 55 Lake Avenue North, Worcester, MA 01655, USA
Am J Surg Pathol 28:999-1006. 2004..Of these features, appendiceal ulceration is highly associated with pouchitis...
Serrated polyps with "intermediate features" of sessile serrated polyp and microvesicular hyperplastic polyp: a practical approach to the classification of nondysplastic serrated polypsSun M Chung
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
Am J Surg Pathol 32:407-12. 2008....
MicroRNA expression aids the preoperative diagnosis of pancreatic ductal adenocarcinomaNicole C Panarelli
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Pancreas 41:685-90. 2012....
Neoadjuvant therapy induces loss of MSH6 expression in colorectal carcinomaFei Bao
Department of Pathology, Columbia University Medical Center, Weill Cornell Medical College, New York, NY, USA
Am J Surg Pathol 34:1798-804. 2010..Therefore, diminished MSH6 staining in treated tumors should prompt immunohistochemical evaluation of pretreatment biopsy samples before genetic testing for Lynch syndrome...
Pitfalls in the interpretation of nonneoplastic mucosal biopsies in inflammatory bowel diseaseRhonda K Yantiss
Department of Pathology and Laboratory Medicine of the Weill Medical College of Cornell University, New York, New York, USA
Am J Gastroenterol 102:890-904. 2007..The potential diagnostic pitfalls faced by physicians, as well as features that aid in the distinction among these entities, are discussed in detail in this review...
Tissue-specific cadherin CDH17 is a useful marker of gastrointestinal adenocarcinomas with higher sensitivity than CDX2Nicole C Panarelli
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Am J Clin Pathol 138:211-22. 2012..Thus, CDH17 is slightly more sensitive than CDX2 when detecting gastrointestinal adenocarcinomas...
Alterations in the immunohistochemical expression of Das-1 and CG-3 in colonic mucosal biopsy specimens helps distinguish ulcerative colitis from Crohn disease and from other forms of colitisRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY
Am J Surg Pathol 32:844-50. 2008..003 for all comparisons). We conclude that the patterns of Das-1 and CG-3 staining in colonic mucosal biopsies may be clinically useful in distinguishing UC from CD and from other colitidies...
Duodenal intraepithelial lymphocytes in inflammatory disorders of the esophagus and stomachMohammad M Yousef
Department of Pathology, UMass Memorial Healthcare, Worcester, Massachusetts 01605, USA
Clin Gastroenterol Hepatol 4:631-4. 2006..This finding may reflect an underlying mechanism of diffuse inflammation in the gastrointestinal tract...
P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reactionEdyta C Pirog
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10065, USA
Am J Surg Pathol 34:1449-55. 2010..These results indicate that a combination of these markers may aid interpretation of anal mucosal biopsy samples...
Normal variation in intraepithelial lymphocytes of the terminal ileumSmiljana Istvanic
Department of Pathology, University of Pittsburgh Medical Center, St Margaret s Hospital, Pittsburgh, PA, USA
Am J Clin Pathol 127:816-9. 2007..One should avoid overinterpreting the importance of occasional IELs in ileal biopsy specimens from asymptomatic patients...
Commercial molecular panels are of limited utility in the classification of pancreatic cystic lesionsNicole C Panarelli
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Am J Surg Pathol 36:1434-43. 2012..We conclude that the PathfinderTG panel may aid the classification of pancreatic lesions, but is often inaccurate and should not replace cytologic evaluation of these lesions...
Immunohistochemical and molecular features of sporadic and FAP-associated duodenal adenomas of the ampullary and nonampullary mucosaPatrick L Wagner
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA
Am J Surg Pathol 32:1388-95. 2008..Similar to colorectal adenomas, they harbor APC and KRAS mutations; but BRAF mutations, p53 alterations, and DNA mismatch repair abnormalities are rare...
KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreasRhonda K Yantiss
Department of Pathology, UMass Memorial Health Care, Worcester, MA 01655, USA
Am J Surg Pathol 29:188-95. 2005..Therefore, immunostains directed against KOC may be of diagnostic utility in the evaluation of pancreatic lesions, particularly when biopsy material is limited...
Effects of cigarette smoke on the human oral mucosal transcriptomeJay O Boyle
Department of Surgery Head and Neck Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Cancer Prev Res (Phila) 3:266-78. 2010....
Pathologic features and biologic importance of colorectal serrated polypsEfsevia Vakiani
Department of Pathology, Memorial Sloan Kettering Cancer Center, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA
Adv Anat Pathol 16:79-91. 2009..This review describes the clinicopathologic and molecular features of serrated polyps and discusses the current data regarding their biologic significance...
Utility of MMP-1, p53, E-cadherin, and collagen IV immunohistochemical stains in the differential diagnosis of adenomas with misplaced epithelium versus adenomas with invasive adenocarcinomaRhonda K Yantiss
Department of Pathology, UMass Memorial Health Care, Worcester, Massachusetts, U.S.A
Am J Surg Pathol 26:206-15. 2002....
Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary glandKotha Subbaramaiah
Department of Medicine and Weill Cornell Cancer Center, New York, NY 10065, USA
Cancer Prev Res (Phila) 4:329-46. 2011..The presence of CLS may be a biomarker of increased breast cancer risk or poor prognosis...
Evaluation of site-specific and seasonal variation in colonic mucosal eosinophilsAlexandros D Polydorides
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
Hum Pathol 39:832-6. 2008..05). We conclude that intramucosal eosinophils are commonly present in the proximal colon but show only mild fluctuations with ambient allergen exposure...
Chasing colonic "polyps": features that predict underlying adenomas in initially nondiagnostic endoscopic biopsy specimensAlexandros D Polydorides
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY, USA
Am J Clin Pathol 127:409-14. 2007..01). We conclude that nondiagnostic biopsy specimens of polyps measuring 5 mm or more should be further evaluated because they are more likely to represent adenomas, whereas smaller lesions are usually clinically inconsequential...
Mucinous neoplasms of the appendix and peritoneumNicole C Panarelli
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10065, USA
Arch Pathol Lab Med 135:1261-8. 2011..As a result, appendiceal mucinous neoplasms and associated peritoneal disease represents one of the most confusing and controversial areas in gastrointestinal pathology...
Localized intrapancreatic malignant mesothelioma: a rare entity that may be confused with other pancreatic neoplasmsRosanny Espinal-Witter
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
Virchows Arch 456:455-61. 2010..This report also describes the clinical and pathologic characteristics of an intrapancreatic mesothelioma and provides a review of the literature regarding entities that may be considered in the differential diagnosis of this tumor...
Multiple gastrointestinal stromal tumors in type I neurofibromatosis: a pathologic and molecular studyRhonda K Yantiss
Department of Pathology, UMass Memorial Health Care, Worcester, MA 01655, USA
Mod Pathol 18:475-84. 2005....
Prevalence and prognostic significance of acinar cell differentiation in pancreatic endocrine tumorsRhonda K Yantiss
Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester 01655, USA
Am J Surg Pathol 26:893-901. 2002..However, in addition to tumor stage, location in the pancreatic tail and the immunohistochemical expression of synaptophysin and/or Leu-7 may be useful prognostic indicators in patients with these lesions...
Metabolic profiling, a noninvasive approach for the detection of experimental colorectal neoplasiaDavid C Montrose
Department of Medicine, Weill Cornell Medical College, New York, USA
Cancer Prev Res (Phila) 5:1358-67. 2012..Collectively, these results provide evidence that metabolomics can be used to detect changes in feces and plasma during azoxymethane-induced colorectal carcinogenesis and thus provide a strong rationale for future studies in humans...
Solitary versus multiple carcinoid tumors of the ileum: a clinical and pathologic review of 68 casesRhonda K Yantiss
Department of Pathology, UMass Memorial Health Care, Worcester, Massachusetts 01655, USA
Am J Surg Pathol 27:811-7. 2003..05). In conclusion, we found that patients with multiple carcinoid tumors are younger, have a significantly greater risk of developing the carcinoid syndrome, and have a poorer prognosis than patients with solitary tumors...
Metastatic Merkel cell carcinoma diagnosed by EUS-guided FNA of a rapidly progressive peripancreatic massTodd P Jessup
Divisions of Gastroenterology and Anatomic Pathology, UMass Memorial Medical Center, Worcester, MA 01655, USA
Gastrointest Endosc 63:527-9. 2006
MicroRNA Expression in Selected Carcinomas of the Gastrointestinal TractNicole C Panarelli
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA
Patholog Res Int 2011:124608. 2011..This paper summarizes the literature regarding miRNA expression in carcinomas of the colon, pancreas, and liver and discusses some of the mechanisms by which these molecules participate in gastrointestinal oncogenesis...
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancerDuncan Hughes
Department of General Surgery, Weill Cornell Medical College, New York, NY 10065, USA
Cancer Prev Res (Phila) 1:241-9. 2008..Collectively, these data indicate that 15-PGDH is commonly down-regulated in NSCLC, an effect that contributes to the accumulation of multiple bioactive lipids in NSCLC...
Intrathoracic gallstones: a case report and literature reviewJacques P Fontaine
Division of Thoracic Surgery, University of Massachusetts Medical Center, Worcester, Massachusetts, USA
JSLS 10:375-8. 2006..CONCLUSION: A high index of suspicion for a gallstone-related problem should be entertained by the practitioner when presented with a patient who has a right lung infiltrate and a history of open or laparoscopic cholecystectomy...
