P J Wittkopp

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Evolutionary changes in cis and trans gene regulation
    Patricia J Wittkopp
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Nature 430:85-8. 2004
  2. ncbi request reprint Genomic sources of regulatory variation in cis and in trans
    P J Wittkopp
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Cell Mol Life Sci 62:1779-83. 2005
  3. ncbi request reprint Evolution of cis-regulatory sequence and function in Diptera
    P J Wittkopp
    Department of Ecology and Evolutionary Biology, University of Michigan, 1061 Natural Science Building, 830 North University Ave, Ann Arbor, MI 48109 1048, USA
    Heredity (Edinb) 97:139-47. 2006
  4. ncbi request reprint Evaluating the role of natural selection in the evolution of gene regulation
    J C Fay
    Department of Genetics, Washington University School of Medicine, St Louis, MO 63108, USA
    Heredity (Edinb) 100:191-9. 2008

Detail Information

Publications4

  1. ncbi request reprint Evolutionary changes in cis and trans gene regulation
    Patricia J Wittkopp
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Nature 430:85-8. 2004
    ..These data indicate that interspecific expression differences are not caused by select trans-regulatory changes with widespread effects, but rather by many cis-acting changes spread throughout the genome...
  2. ncbi request reprint Genomic sources of regulatory variation in cis and in trans
    P J Wittkopp
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Cell Mol Life Sci 62:1779-83. 2005
    ..I argue that the molecular function of the protein encoded by each gene and how the gene is wired into the genomic regulatory network may influence its propensity for cis and trans regulatory changes...
  3. ncbi request reprint Evolution of cis-regulatory sequence and function in Diptera
    P J Wittkopp
    Department of Ecology and Evolutionary Biology, University of Michigan, 1061 Natural Science Building, 830 North University Ave, Ann Arbor, MI 48109 1048, USA
    Heredity (Edinb) 97:139-47. 2006
    ..Biochemical characterization and in vivo assays of cis-regulatory sequences on a genomic-scale will relieve this barrier...
  4. ncbi request reprint Evaluating the role of natural selection in the evolution of gene regulation
    J C Fay
    Department of Genetics, Washington University School of Medicine, St Louis, MO 63108, USA
    Heredity (Edinb) 100:191-9. 2008
    ....