M Wiedmann

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Lineage specific recombination rates and microevolution in Listeria monocytogenes
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Evol Biol 8:277. 2008
  2. doi request reprint Assessment criteria and approaches for rapid detection methods to be used in the food industry
    Martin Wiedmann
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 77:670-90. 2014
  3. pmc Genomic characterization provides new insight into Salmonella phage diversity
    Andrea I Moreno Switt
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    BMC Genomics 14:481. 2013
  4. pmc Protein level identification of the Listeria monocytogenes sigma H, sigma L, and sigma C regulons
    Sana Mujahid
    Department of Food Science, Cornell University, 412 Stocking Hall, Ithaca, NY, USA
    BMC Microbiol 13:156. 2013
  5. pmc Correction: Wiedmann, M., et al. Exploration of the Role of the Non-Coding RNA SbrE in L. monocytogenes Stress Response. Int. J. Mol. Sci. 2013, 14, 378-393
    Sana Mujahid
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Int J Mol Sci 14:9685. 2013
  6. pmc Exploration of the Role of the Non-Coding RNA SbrE in L. monocytogenes Stress Response
    Sana Mujahid
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Int J Mol Sci 14:378-93. 2012
  7. pmc Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 12:425. 2011
  8. pmc Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene loss
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 11:688. 2010
  9. pmc Short-term genome evolution of Listeria monocytogenes in a non-controlled environment
    Renato H Orsi
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Genomics 9:539. 2008
  10. pmc Homopolymeric tracts represent a general regulatory mechanism in prokaryotes
    Renato H Orsi
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 11:102. 2010

Research Grants

Detail Information

Publications130 found, 100 shown here

  1. pmc Lineage specific recombination rates and microevolution in Listeria monocytogenes
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Evol Biol 8:277. 2008
    ..monocytogenes. Analyses were performed using sequences for seven loci (including the house-keeping genes gap, prs, purM and ribC, the stress response gene sigB, and the virulence genes actA and inlA) for 195 L. monocytogenes isolates...
  2. doi request reprint Assessment criteria and approaches for rapid detection methods to be used in the food industry
    Martin Wiedmann
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 77:670-90. 2014
    ..This article is intended to provide an overall outline of criteria that the food industry can use to evaluate new rapid detection methods, with a specific focus on nucleic acid-based detection methods. ..
  3. pmc Genomic characterization provides new insight into Salmonella phage diversity
    Andrea I Moreno Switt
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    BMC Genomics 14:481. 2013
    ....
  4. pmc Protein level identification of the Listeria monocytogenes sigma H, sigma L, and sigma C regulons
    Sana Mujahid
    Department of Food Science, Cornell University, 412 Stocking Hall, Ithaca, NY, USA
    BMC Microbiol 13:156. 2013
    ..e., σL, σH, and σC; strains ΔBCH, ΔBCL, and ΔBHL) to eliminate potential redundancies between σ factors...
  5. pmc Correction: Wiedmann, M., et al. Exploration of the Role of the Non-Coding RNA SbrE in L. monocytogenes Stress Response. Int. J. Mol. Sci. 2013, 14, 378-393
    Sana Mujahid
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Int J Mol Sci 14:9685. 2013
    ..05 (expectation value) were further analyzed". The authors would like to apologize for any inconvenience this may have caused to the readers of this journal...
  6. pmc Exploration of the Role of the Non-Coding RNA SbrE in L. monocytogenes Stress Response
    Sana Mujahid
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Int J Mol Sci 14:378-93. 2012
    ..Our data suggest that σB-dependent transcription of SbrE represents a conserved mechanism that contributes, across Listeria species, to fine-tuning of gene expression under specific environmental conditions that remain to be defined...
  7. pmc Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 12:425. 2011
    ..Here we used a comparative genomics approach to define the population structure of Salmonella enterica subsp. enterica, and identify clade-specific genes that may be the result of ecological specialization...
  8. pmc Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene loss
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 11:688. 2010
    ....
  9. pmc Short-term genome evolution of Listeria monocytogenes in a non-controlled environment
    Renato H Orsi
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Genomics 9:539. 2008
    ..While a genome sequence for the 1988 food isolate has been reported, we sequenced the genomes of the 1988 human isolate as well as a human and a food isolate from the 2000 outbreak to allow for comparative genome analyses...
  10. pmc Homopolymeric tracts represent a general regulatory mechanism in prokaryotes
    Renato H Orsi
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 11:102. 2010
    ..g., phase variation...
  11. pmc Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs
    Haley F Oliver
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Genomics 10:641. 2009
    ....
  12. pmc Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypes
    Yesim Soyer
    Department of Food Science, Cornell University, 412 Stocking Hall, Ithaca, NY 14853, USA
    BMC Evol Biol 9:264. 2009
    ....
  13. pmc Genome-wide analyses reveal lineage specific contributions of positive selection and recombination to the evolution of Listeria monocytogenes
    Renato H Orsi
    Department of Food Science, Cornell University, Ithaca, NY, USA
    BMC Evol Biol 8:233. 2008
    ..innocua strain and four L. monocytogenes strains representing lineages I and II, to characterize the contributions of positive selection and recombination to the evolution of the L. innocua/L. monocytogenes core genome...
  14. ncbi request reprint Pathogen, host and environmental factors contributing to the pathogenesis of listeriosis
    A J Roberts
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    Cell Mol Life Sci 60:904-18. 2003
    ....
  15. pmc Select Listeria monocytogenes subtypes commonly found in foods carry distinct nonsense mutations in inlA, leading to expression of truncated and secreted internalin A, and are associated with a reduced invasion phenotype for human intestinal epithelial ce
    K K Nightingale
    Cornell University, Department of Food Science, 412 Stocking Hall, Ithaca, NY 14853
    Appl Environ Microbiol 71:8764-72. 2005
    ..monocytogenes subtypes which are common among U.S. food isolates but rare among human listeriosis isolates carry inlA mutations that are associated with, and possibly at least partially responsible for, an attenuated invasion phenotype...
  16. pmc Ribotypes and virulence gene polymorphisms suggest three distinct Listeria monocytogenes lineages with differences in pathogenic potential
    M Wiedmann
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 65:2707-16. 1997
    ..monocytogenes subspecies. None of the 20 human isolates available but 11% of our animal isolates were grouped in this lineage, indicating that strains in this lineage might have reduced virulence for humans...
  17. pmc Microarray-based characterization of the Listeria monocytogenes cold regulon in log- and stationary-phase cells
    Yvonne C Chan
    Department of Food Science, Cornell University, Ithica, NY 14853, USA
    Appl Environ Microbiol 73:6484-98. 2007
    ..monocytogenes genes with lower transcript levels at 4 degrees C include a number of virulence and virulence-associated genes as well as some heat shock genes...
  18. ncbi request reprint Molecular subtyping methods for Listeria monocytogenes
    Martin Wiedmann
    Cornell University, Department of Food Science, Ithaca, NY 14853, USA
    J AOAC Int 85:524-31. 2002
    ..A significant focus is on the application of subtyping methods to define L. monocytogenes subtypes and clonal groups, which may differ in phenotypic characteristics and pathogenic potential...
  19. ncbi request reprint Listeriosis outbreak in dairy cattle caused by an unusual Listeria monocytogenes serotype 4b strain
    Brittany N Bundrant
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA
    J Vet Diagn Invest 23:155-8. 2011
    ..monocytogenes strains. Continued monitoring of animal listeriosis cases and outbreaks may not only improve animal health but also aid in the early discovery of newly emerging L. monocytogenes strains...
  20. pmc The prevalence of multidrug resistance is higher among bovine than human Salmonella enterica serotype Newport, Typhimurium, and 4,5,12:i:- isolates in the United States but differs by serotype and geographic region
    K Hoelzer
    Department of Food Science, Cornell University, 410 Stocking Hall, Ithaca, NY 14850, USA
    Appl Environ Microbiol 76:5947-59. 2010
    ..In addition, the study provides evidence for the value of including antimicrobial resistance data in epidemiological investigations and highlights the benefits and potential problems of combining subtyping methods...
  21. pmc Listeria monocytogenes {sigma}B has a small core regulon and a conserved role in virulence but makes differential contributions to stress tolerance across a diverse collection of strains
    H F Oliver
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 76:4216-32. 2010
    ..Our results suggest that sigma(B) universally contributes to L. monocytogenes virulence but specific sigma(B)-regulated stress response phenotypes vary among strains...
  22. pmc Multilocus sequence typing supports the hypothesis that cow- and human-associated Salmonella isolates represent distinct and overlapping populations
    S D Alcaine
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 72:7575-85. 2006
    ..We conclude that the combined use of an economical three-gene MLST scheme and serotyping can provide considerable new insights into the evolution and transmission of Salmonella...
  23. pmc inlA premature stop codons are common among Listeria monocytogenes isolates from foods and yield virulence-attenuated strains that confer protection against fully virulent strains
    K K Nightingale
    Department of Food Science, Cornell University, Ithaca, New York 148531, USA
    Appl Environ Microbiol 74:6570-83. 2008
    ..monocytogenes strains commonly found in food confer protective immunity...
  24. pmc Salmonella enterica serotype 4,5,12:i:-, an emerging Salmonella serotype that represents multiple distinct clones
    Y Soyer
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    J Clin Microbiol 47:3546-56. 2009
    ..Salmonella serotype 4,5,12:i:- thus appears to represent at least two common clones, which cannot easily be differentiated with standard diagnostic procedures...
  25. ncbi request reprint Listeria monocytogenes F2365 carries several authentic mutations potentially leading to truncated gene products, including inlB, and demonstrates atypical phenotypic characteristics
    K K Nightingale
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 70:482-8. 2007
    ..Our results support that L. monocytogenes F2365 is characterized by genotypic and phenotypic properties that are atypical of other L. monocytogenes strains...
  26. ncbi request reprint The combination of lactate and diacetate synergistically reduces cold growth in brain heart infusion broth across Listeria monocytogenes lineages
    Matthew J Stasiewicz
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 73:631-40. 2010
    ..monocytogenes at refrigeration temperature in broth, and justifies combining these inhibitors, at effective levels, in food product formulations...
  27. ncbi request reprint Comparative genetic characterization of Listeria monocytogenes isolates from human and animal listeriosis cases
    G T Jeffers
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Microbiology 147:1095-104. 2001
    ..This study also establishes baseline data describing the genetic diversity of human and animal L. monocytogenes isolates which can be utilized in future surveillance programmes to track the emergence of new strains...
  28. ncbi request reprint Longitudinal studies on Listeria in smoked fish plants: impact of intervention strategies on contamination patterns
    Victoria R Lappi
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 67:2500-14. 2004
    ..and L. monocytogenes in the plant environment, elimination of persistent L. monocytogenes strains remains a considerable challenge...
  29. ncbi request reprint Tracking of Listeria monocytogenes in smoked fish processing plants
    Joanne Thimothe
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 67:328-41. 2004
    ..Molecular subtyping methods can help identify plant-specific L. monocytogenes contamination routes and thus provide the knowledge needed to implement improved L. monocytogenes control strategies...
  30. pmc Differential regulation of Listeria monocytogenes internalin and internalin-like genes by sigmaB and PrfA as revealed by subgenomic microarray analyses
    Patrick McGann
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Foodborne Pathog Dis 5:417-35. 2008
    ....
  31. pmc Salmonella Cerro isolated over the past twenty years from various sources in the US represent a single predominant pulsed-field gel electrophoresis type
    K Hoelzer
    Department of Food Science, Cornell University, Ithaca, NY 14850, USA
    Vet Microbiol 150:389-93. 2011
    ....
  32. ncbi request reprint Recombination and positive selection contribute to evolution of Listeria monocytogenes inlA
    R H Orsi
    Department of Food Science, Cornell University, Ithaca, NY, USA
    Microbiology 153:2666-78. 2007
    ..monocytogenes' natural history as an environmental pathogen with broad host-range, including its adaptation to environments and hosts where different inlA alleles may provide a selective advantage or where inlA may not be required...
  33. ncbi request reprint Characterization of the prfA virulence gene cluster insertion site in non-hemolytic Listeria spp.: probing the evolution of the Listeria virulence gene island
    S Cai
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Curr Microbiol 43:271-7. 2001
    ..Our results are consistent with the hypothesis that a combination of horizontal gene transfer and deletion events mayhave been involved in the evolution of the prfA virulence gene cluster in Listeria...
  34. ncbi request reprint Longitudinal monitoring of Listeria monocytogenes contamination patterns in a farmstead dairy processing facility
    A J Ho
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 90:2517-24. 2007
    ..Preventing cross contamination between dairy production and processing facilities and control of persistent L. monocytogenes are thus critical to assuring the microbial safety of farmstead dairy products...
  35. ncbi request reprint Listeria monocytogenes fecal shedding in dairy cattle shows high levels of day-to-day variation and includes outbreaks and sporadic cases of shedding of specific L. monocytogenes subtypes
    A J Ho
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Prev Vet Med 80:287-305. 2007
    ..monocytogenes subtype on any given day. Although limited to a single dairy cattle herd, these findings provide a significant advancement in the understanding of the epidemiology of L. monocytogenes fecal shedding in dairy cattle...
  36. pmc Transcriptomic and phenotypic analyses suggest a network between the transcriptional regulators HrcA and sigmaB in Listeria monocytogenes
    Yuewei Hu
    Department of Food Science, 413 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 73:7981-91. 2007
    ..monocytogenes genes...
  37. pmc Phenotypic and transcriptomic analyses demonstrate interactions between the transcriptional regulators CtsR and Sigma B in Listeria monocytogenes
    Yuewei Hu
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 73:7967-80. 2007
    ..Our data demonstrate that interactions between CtsR and sigma(B) play an important role in L. monocytogenes stress resistance and virulence...
  38. ncbi request reprint Associations among Listeria monocytogenes genotypes and distinct clinical manifestations of listeriosis in cattle
    Mary Ann Pohl
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Am J Vet Res 67:616-26. 2006
    ....
  39. ncbi request reprint Listeria monocytogenes contamination patterns for the smoked fish processing environment and for raw fish
    Adam D Hoffman
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 66:52-60. 2003
    ..We also conclude that regular L. monocyrogenes testing of drains, combined with molecular subtyping of the isolates obtained, allows for efficient monitoring of persistent L. monocytogenes contamination in a processing plant...
  40. ncbi request reprint Distribution of Listeria monocytogenes molecular subtypes among human and food isolates from New York State shows persistence of human disease--associated Listeria monocytogenes strains in retail environments
    Brian D Sauders
    Department of Food Science, Cornell University, Ithaca, New York, USA
    J Food Prot 67:1417-28. 2004
    ..Implementation of Listeria control procedures in retail operations, which process and handle products that permit the growth of L. monocytogenes, are thus a critical component of a farm-to-table L. monocytogenes control program...
  41. doi request reprint Evaluation of various selective media for the detection of Pseudomonas species in pasteurized milk
    J A Van Tassell
    Milk Quality Improvement Program, Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 95:1568-74. 2012
    ..89) incubated at 32 °C for 48 h. Overall, plating milk samples on CVTA followed by a 48-h incubation at 32 °C was the most effective selective method for recovering a diversity of Pseudomonas spp. from milk...
  42. doi request reprint When cheese gets the blues: Pseudomonas fluorescens as the causative agent of cheese spoilage
    N H Martin
    Milk Quality Improvement Program, Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 94:3176-83. 2011
    ..e., an overhead cheese vat agitator system) as the likely source of product contamination...
  43. ncbi request reprint Combined sigB allelic typing and multiplex PCR provide improved discriminatory power and reliability for Listeria monocytogenes molecular serotyping
    Kendra Nightingale
    Department of Food Science, Cornell University, Ithaca, NY, USA
    J Microbiol Methods 68:52-9. 2007
    ..This combined approach also differentiates lineage I serotype 4b isolates from the genetically distinct serotype 4b isolates classified into lineage III...
  44. pmc Listeria monocytogenes sigma B regulates stress response and virulence functions
    Mark J Kazmierczak
    Department of Food Science, Cornell University, Ithaca, New York, USA
    J Bacteriol 185:5722-34. 2003
    ..monocytogenes. These findings strongly suggest that sigma(B) contributes to L. monocytogenes gene expression during infection...
  45. ncbi request reprint Prevalence and growth of Listeria on naturally contaminated smoked salmon over 28 days of storage at 4 degrees C
    Victoria R Lappi
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 67:1022-6. 2004
    ..However, because of the apparent heterogeneity of Listeria distribution within samples, the interpretation of growth data collected on naturally contaminated samples is difficult...
  46. ncbi request reprint Molecular epidemiology and cluster analysis of human listeriosis cases in three U.S. states
    Brian D Sauders
    Department of Food ScienceCornell University, Ithaca, New York 14853, USA
    J Food Prot 69:1680-9. 2006
    ..L. monocytogenes lineages and EcoRI ribotypes do not appear to differ in their likelihood of causing different clinical manifestations or mortality...
  47. pmc Comparative analysis of the sigma B-dependent stress responses in Listeria monocytogenes and Listeria innocua strains exposed to selected stress conditions
    Sarita Raengpradub
    Department of Food Science, 413 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 74:158-71. 2008
    ..monocytogenes and L. innocua sigma(B) regulons show considerable conservation, with a common set of at least 49 genes that are sigma(B) dependent in both species...
  48. doi request reprint Growth and persistence of Listeria monocytogenes isolates on the plant model Arabidopsis thaliana
    Sara R Milillo
    Department of Food Science, Cornell University, 412 Stocking Hall, Ithaca, NY 14853, USA
    Food Microbiol 25:698-704. 2008
    ..Overall, our study demonstrates that prevention of L. monocytogenes contamination of plants throughout growing stages is critical, consistent with recommendations for other produce-transmitted foodborne pathogens...
  49. pmc Refinement of the Listeria monocytogenes σB regulon through quantitative proteomic analysis
    S Mujahid
    Department of Food Science, Cornell University, Ithaca, NY, USA
    Microbiology 159:1109-19. 2013
    ..monocytogenes energy metabolism as well as a role of PrfA and σ(B) interaction in regulating aspects of energy metabolism in L. monocytogenes...
  50. doi request reprint Listeria monocytogenes and hemolytic Listeria innocua in poultry
    S R Milillo
    Center for Food Safety, Department of Food Science, University of Arkansas, Fayetteville 72704, USA
    Poult Sci 91:2158-63. 2012
    ..Our data indicate that both pasture-reared poultry and their environment can be contaminated with L. monocytogenes and hemolytic L. innocua...
  51. pmc Sigma B contributes to Listeria monocytogenes gastrointestinal infection but not to systemic spread in the guinea pig infection model
    M R Garner
    Department of Food Science, 413 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Infect Immun 74:876-86. 2006
    ....
  52. pmc Ceftiofur-resistant Salmonella strains isolated from dairy farms represent multiple widely distributed subtypes that evolved by independent horizontal gene transfer
    S D Alcaine
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Antimicrob Agents Chemother 49:4061-7. 2005
    ....
  53. ncbi request reprint Listeria monocytogenes internalins are highly diverse and evolved by recombination and positive selection
    Yeu Harn L Tsai
    Department of Food Science, Cornell University, Ithaca, NY, USA
    Infect Genet Evol 6:378-89. 2006
    ..monocytogenes, (iii) both intragenic recombination and positive selection have contributed to the evolution of L. monocytogenes internalins, and (iv) L. monocytogenes internalins show distinct evolutionary histories...
  54. pmc Pulsed-field gel electrophoresis diversity of human and bovine clinical Salmonella isolates
    Yesim Soyer
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Foodborne Pathog Dis 7:707-17. 2010
    ....
  55. doi request reprint Multilocus sequence typing of outbreak-associated Listeria monocytogenes isolates to identify epidemic clones
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Foodborne Pathog Dis 7:257-65. 2010
    ..monocytogenes subtypes, including those representing previously described ECs...
  56. ncbi request reprint Daily variability of Listeria contamination patterns in a cold-smoked salmon processing operation
    Yuewei Hu
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 69:2123-33. 2006
    ....
  57. pmc Emergence, distribution, and molecular and phenotypic characteristics of Salmonella enterica serotype 4,5,12:i:-
    Andrea I Moreno Switt
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Foodborne Pathog Dis 6:407-15. 2009
    ..This paper discusses our current knowledge of the global ecology, epidemiology, transmission, and evolution of this emerging Salmonella serotype...
  58. pmc Sigma B contributes to PrfA-mediated virulence in Listeria monocytogenes
    Celine A Nadon
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 70:3948-52. 2002
    ..monocytogenes. Thus, the alternative sigma factor sigma(B) contributes to virulence in L. monocytogenes...
  59. pmc Exposure to salt and organic acids increases the ability of Listeria monocytogenes to invade Caco-2 cells but decreases its ability to survive gastric stress
    Matthew R Garner
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 72:5384-95. 2006
    ..These findings suggest that virulence-associated characteristics that determine the L. monocytogenes infectious dose are likely to be affected by food-specific properties (e.g., pH or the presence of salt or organic acid)...
  60. ncbi request reprint Contributions of Listeria monocytogenes sigmaB and PrfA to expression of virulence and stress response genes during extra- and intracellular growth
    Mark J Kazmierczak
    Department of Food Science, Cornell University, Ithaca, 413 Stocking Hall, NY 14853, USA
    Microbiology 152:1827-38. 2006
    ..monocytogenes and (ii) the partially sigmaB-dependent P2prfA promoter region contributes the majority of prfA transcripts in both intra- and extracellular bacteria...
  61. ncbi request reprint sigmaB-dependent gene induction and expression in Listeria monocytogenes during osmotic and acid stress conditions simulating the intestinal environment
    David Sue
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Microbiology 150:3843-55. 2004
    ..As inlA, bsh and opuCA are critical for gastrointestinal infections in animal models, the data also suggest that sigma(B) contributes to the ability of L. monocytogenes to cause foodborne infections...
  62. ncbi request reprint Sigma(B)-dependent expression patterns of compatible solute transporter genes opuCA and lmo1421 and the conjugated bile salt hydrolase gene bsh in Listeria monocytogenes
    David Sue
    Department of Food Science, Cornell University, 412 Stocking Hall, Ithaca, NY 14853, USA
    Microbiology 149:3247-56. 2003
    ..monocytogenes virulence, the data presented here provide further evidence of specific sigma(B)-mediated contributions to both environmental stress resistance and intra-host survival in L. monocytogenes...
  63. doi request reprint A decade of improvement: New York State fluid milk quality
    N H Martin
    Milk Quality Improvement Program, Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 95:7384-90. 2012
    ..This study demonstrates that overall fluid milk quality in NYS, as determined by microbiological and sensory analyses, has improved over the last decade, and identifies some challenges that remain...
  64. pmc Listeria monocytogenes grown at 7° C shows reduced acid survival and an altered transcriptional response to acid shock compared to L. monocytogenes grown at 37° C
    R A Ivy
    Department of Food Science, Cornell University, Ithaca, NY, USA
    Appl Environ Microbiol 78:3824-36. 2012
    ..monocytogenes to survive gastric passage and ultimately cause disease...
  65. pmc Evolution and molecular phylogeny of Listeria monocytogenes isolated from human and animal listeriosis cases and foods
    K K Nightingale
    Department of Food Science, Cornell University, 412B Stocking Hall, Ithaca, NY 14853, USA
    J Bacteriol 187:5537-51. 2005
    ..monocytogenes...
  66. ncbi request reprint ADSA Foundation Scholar Award--An integrated science-based approach to dairy food safety: Listeria monocytogenes as a model system
    M Wiedmann
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 86:1865-75. 2003
    ....
  67. pmc Ecology and transmission of Listeria monocytogenes infecting ruminants and in the farm environment
    K K Nightingale
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 70:4458-67. 2004
    ..monocytogenes, including subtypes linked to human listeriosis cases and outbreaks, and (iv) L. monocytogenes subtypes may differ in their abilities to infect animals and to survive in farm environments...
  68. pmc Lineage specific recombination and positive selection in coding and intragenic regions contributed to evolution of the main Listeria monocytogenes virulence gene cluster
    Renato H Orsi
    Department of Food Science, Cornell University, 412B Stocking Hall, Ithaca, NY 14853, USA
    Infect Genet Evol 8:566-76. 2008
    ..monocytogenes virulence gene cluster thus have evolved independently, despite their close physical linkage, likely reflecting distinct selective pressures associated with expression and function of the proteins encoded in this region...
  69. ncbi request reprint Contributions of two-component regulatory systems, alternative sigma factors, and negative regulators to Listeria monocytogenes cold adaptation and cold growth
    Yvonne C Chan
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 71:420-5. 2008
    ..monocytogenes growth at 4 degrees C in rich media, and (ii) inoculum concentration and pregrowth conditions affect the L. monocytogenes cold-growth phenotype...
  70. pmc SigmaB- and PrfA-dependent transcription of genes previously classified as putative constituents of the Listeria monocytogenes PrfA regulon
    Juliane Ollinger
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Foodborne Pathog Dis 5:281-93. 2008
    ..monocytogenes 10403S, while sigma(B) regulates a wider range of virulence and stress response genes...
  71. pmc Rational design of DNA sequence-based strategies for subtyping Listeria monocytogenes
    Steven Cai
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Clin Microbiol 40:3319-25. 2002
    ..Our specific results also show that inclusion of virulence gene target sequences in a DNA sequence-based subtyping scheme for L. monocytogenes is necessary to achieve maximum subtype differentiation...
  72. pmc SigmaB-dependent and sigmaB-independent mechanisms contribute to transcription of Listeria monocytogenes cold stress genes during cold shock and cold growth
    Yvonne C Chan
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Appl Environ Microbiol 73:6019-29. 2007
    ..We conclude that sigma(B)-dependent and sigma(B)-independent mechanisms contribute to the ability of L. monocytogenes to survive and grow at low temperatures...
  73. pmc sigma(B) and sigma(L) contribute to Listeria monocytogenes 10403S response to the antimicrobial peptides SdpC and nisin
    M Elizabeth Palmer
    Department of Food Science, Cornell University, Ithaca, New York, USA
    Foodborne Pathog Dis 6:1057-65. 2009
    ..In summary, while the sigma(B)-dependent lmo2570 does not contribute to resistance of L. monocytogenes to nisin or SdpC, both sigma(B) and sigma(L) contribute to the L. monocytogenes antimicrobial response...
  74. pmc Definition of genetically distinct attenuation mechanisms in naturally virulence-attenuated Listeria monocytogenes by comparative cell culture and molecular characterization
    Angela Roberts
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 71:3900-10. 2005
    ..monocytogenes...
  75. ncbi request reprint Molecular characterization of Listeria monocytogenes from natural and urban environments
    Brian D Sauders
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 69:93-105. 2006
    ..monocytogenes lineage II, which supports the classification of this lineage as an environmentally adapted subgroup...
  76. ncbi request reprint Antimicrobial resistance in nontyphoidal Salmonella
    Samuel D Alcaine
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 70:780-90. 2007
    ....
  77. pmc General stress transcription factor sigmaB and its role in acid tolerance and virulence of Listeria monocytogenes
    M Wiedmann
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York 14853, USA
    J Bacteriol 180:3650-6. 1998
    ..Our results suggest that sigmaB-directed genes do not appear to be essential for the spread of L. monocytogenes to mouse liver or spleen at 2 and 4 days following intragastric or intraperitoneal infection...
  78. pmc Diverse geno- and phenotypes of persistent Listeria monocytogenes isolates from fermented meat sausage production facilities in Portugal
    V Ferreira
    CBQF Escola Superior de Biotecnologia, Universidade Catolica Portuguesa, Porto, Portugal
    Appl Environ Microbiol 77:2701-15. 2011
    ..monocytogenes in this food chain is common. (iii) Persistent L. monocytogenes strains are diverse and do not appear to be characterized by unique genetic or phenotypic characteristics...
  79. doi request reprint Fecal shedding of, antimicrobial resistance in, and serologic response to Salmonella Typhimurium in dairy calves
    Kimberly A Alexander
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Am Vet Med Assoc 235:739-48. 2009
    ..To determine the duration of fecal shedding of and serologic response to Salmonella spp after natural infection in dairy calves and characterize Salmonella organisms recovered from these herds...
  80. ncbi request reprint Impact of intervention strategies on Listeria contamination patterns in crawfish processing plants: a longitudinal study
    Victoria R Lappi
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 67:1163-9. 2004
    ..prevalences for raw crawfish of more than 50%...
  81. ncbi request reprint Comparative genomic analysis of the sigB operon in Listeria monocytogenes and in other Gram-positive bacteria
    Adriana Ferreira
    Department of Food Science, Cornell University, 413 Stocking Hall, Ithaca, NY 14853, USA
    Curr Microbiol 48:39-46. 2004
    ..Differential evolution of this stress response system among various genera may represent a strategy that enables bacteria to adapt cellular response and survival systems to a variety of stress conditions...
  82. pmc Molecular subtyping and characterization of bovine and human Streptococcus agalactiae isolates
    Sharinne Sukhnanand
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    J Clin Microbiol 43:1177-86. 2005
    ..agalactiae; (ii) most human invasive and bovine S. agalactiae isolates represent distinct subtypes, suggesting limited interspecies transmission; and (iii) hyaluronidase activity is not required for all human infections...
  83. doi request reprint Physiology and genetics of Listeria monocytogenes survival and growth at cold temperatures
    Yvonne C Chan
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Crit Rev Food Sci Nutr 49:237-53. 2009
    ..Further improvement in our understanding of the physiology and genetics of L. monocytogenes cold growth will hopefully enhance our ability to design successful intervention strategies for this foodborne pathogen...
  84. pmc Complementation of Listeria monocytogenes null mutants with selected Listeria seeligeri virulence genes suggests functional adaptation of Hly and PrfA and considerable diversification of prfA regulation in L. seeligeri
    Courtney R Lucas Stelling
    Graduate Field of Microbiology, Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Appl Environ Microbiol 76:5124-39. 2010
    ..seeligeri and L. monocytogenes. Virulence gene homologues and their expression thus appear to have adapted to distinct but possibly related functions in these two species...
  85. doi request reprint Antimicrobial resistant Salmonella in dairy cattle in the United States
    Kimberly A Alexander
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA
    Vet Res Commun 33:191-209. 2009
    ....
  86. pmc Temperature-dependent expression of Listeria monocytogenes internalin and internalin-like genes suggests functional diversity of these proteins among the listeriae
    Patrick McGann
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Appl Environ Microbiol 73:2806-14. 2007
    ..The temperature-dependent transcription patterns suggest that the relative importance of different internalins varies by environment, which may provide insight into the specific functions of these proteins...
  87. ncbi request reprint Eye infections due to Listeria monocytogenes in three cows and one horse
    Katie Evans
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA
    J Vet Diagn Invest 16:464-9. 2004
    ..Although listerial eye infections are rarely diagnosed because of its ubiquitous nature, L. monocytogenes may have to be considered more commonly as a causative agent of eye infections in ruminants and horses...
  88. pmc DNA sequence-based subtyping and evolutionary analysis of selected Salmonella enterica serotypes
    Sharinne Sukhnanand
    Department of Food Science, 412 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    J Clin Microbiol 43:3688-98. 2005
    ..Three-gene sequence typing also supports the notion that Salmonella serotypes represent both monophyletic and polyphyletic lineages...
  89. ncbi request reprint Evaluation of farm management practices as risk factors for clinical listeriosis and fecal shedding of Listeria monocytogenes in ruminants
    Kendra K Nightingale
    Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA
    J Am Vet Med Assoc 227:1808-14. 2005
    ..To assess seasonal variation in prevalence of Listeria monocytogenes on ruminant farms and identify management practices associated with ruminant listeriosis and fecal shedding of L. monocytogenes...
  90. ncbi request reprint International Life Sciences Institute North America Listeria monocytogenes strain collection: development of standard Listeria monocytogenes strain sets for research and validation studies
    Eric Fugett
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 69:2929-38. 2006
    ..We have thus developed a core L. monocytogenes strain collection, which will provide a resource for L. monocytogenes research and development efforts with centralized Internet-based data curation and integration...
  91. pmc Pulsed-field gel electrophoresis (PFGE) analysis of temporally matched Listeria monocytogenes isolates from human clinical cases, foods, ruminant farms, and urban and natural environments reveals source-associated as well as widely distributed PFGE types
    Eric B Fugett
    Department of Food Sciences, Cornell University, 412 Stocking Hall, Ithaca, NY 14853, USA
    J Clin Microbiol 45:865-73. 2007
    ..Large PFGE type databases representing isolates from different sources are thus needed to appropriately interpret subtype data in epidemiological investigations and to identify common as well as source-specific PFGE types...
  92. ncbi request reprint Recurrent Listeria monocytogenes infection: relapse or reinfection with a unique strain confirmed by molecular subtyping
    B D Sauders
    New York State Department of Health, Wadsworth Center, Albany, NY, USA
    Clin Infect Dis 33:257-9. 2001
    ..This case report illustrates the potential use of molecular subtyping to further understand the pathogenesis and epidemiology of listeriosis and the potential for relapse of Listeria infections in humans...
  93. pmc Equine stomachs harbor an abundant and diverse mucosal microbiota
    G A Perkins
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Appl Environ Microbiol 78:2522-32. 2012
    ..present in the glandular region of the stomach. The equine stomach harbors an abundant and diverse mucosal microbiota that varies by individual...
  94. doi request reprint Reduction of pasteurization temperature leads to lower bacterial outgrowth in pasteurized fluid milk during refrigerated storage: a case study
    N H Martin
    Milk Quality Improvement Program, Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 95:471-5. 2012
    ..Lowering the pasteurization temperature for unflavored fluid milk processed in a commercial processing facility significantly reduced bacterial growth during refrigerated storage...
  95. ncbi request reprint Characterization of rpoS alleles in Escherichia coli O157:H7 and in other E. coli serotypes
    A Ferreira
    Cornell University, Food Science Department, Ithaca, NY 14853, USA
    J Appl Microbiol 86:295-301. 1999
    ..5. It was also found that all E. coli O157:H7 isolates tested had a unique nucleotide at position 543, thus differentiating these strains from other E. coli serotypes...
  96. pmc Correlations between molecular subtyping and serotyping of Listeria monocytogenes
    C A Nadon
    Cornell University, Ithaca, New York 14853, USA
    J Clin Microbiol 39:2704-7. 2001
    ..Of the 12 resultant EcoRI-PvuII combination types, only 4 contained multiple serotypes, demonstrating the potential of ribotyping for serotype prediction...
  97. doi request reprint Results from raw milk microbiological tests do not predict the shelf-life performance of commercially pasteurized fluid milk
    N H Martin
    Milk Quality Improvement Program, Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 94:1211-22. 2011
    ..Our findings suggest the need for new raw milk tests that measure the specific biological barriers that limit shelf-life and quality of fluid milk products...
  98. ncbi request reprint Molecular Subtyping and Tracking of Listeria monocytogenes in Latin-Style Fresh-Cheese Processing Plants
    D Y Kabuki
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    J Dairy Sci 87:2803-12. 2004
    ....
  99. pmc Novel method to identify source-associated phylogenetic clustering shows that Listeria monocytogenes includes niche-adapted clonal groups with distinct ecological preferences
    K K Nightingale
    Department of Food Science, Cornell University, Ithaca, NY, USA
    J Clin Microbiol 44:3742-51. 2006
    ..monocytogenes includes clonal groups that have adapted to infect specific host species or colonize nonhost environments...
  100. ncbi request reprint Comparative evaluation of culture- and BAX polymerase chain reaction-based detection methods for Listeria spp. and Listeria monocytogenes in environmental and raw fish samples
    A D Hoffman
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 64:1521-6. 2001
    ..and L. monocytogenes. While the BAX systems provide screening results in about 3 days, the use of LMPM allows for L. monocytogenes isolation in 4 to 5 days...
  101. ncbi request reprint Markov chain approach to analyze the dynamics of pathogen fecal shedding--example of Listeria monocytogenes shedding in a herd of dairy cattle
    Renata Ivanek
    Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Theor Biol 245:44-58. 2007
    ....

Research Grants4

  1. L. MONOCYTOGENES CLONAL GROUPS: ECOLOGY AND TRANSMISSION
    Martin Wiedmann; Fiscal Year: 2004
    ..4. Determine the phenotypes of L. monocytogenes clonal groups associated with specific environments and hosts and determine the genetic basis for phenotypes associated with a preference for specific habitats...