M Wiedmann


Affiliation: Cornell University
Country: USA


  1. Buehler A, Evanowski R, Wiedmann M, Martin N. Internal transcribed spacer (ITS) sequence-based characterization of fungal isolates from multiple yogurt facilities-A case study. J Dairy Sci. 2019;: pubmed publisher
    ..Developing and implementing sampling plans that comprehensively capture yeast and mold diversity in a given processing facility remain a considerable challenge. ..
  2. Buehler A, Martin N, Boor K, Wiedmann M. Evaluation of biopreservatives in Greek yogurt to inhibit yeast and mold spoilage and development of a yogurt spoilage predictive model. J Dairy Sci. 2018;101:10759-10774 pubmed publisher
  3. Reichler S, Trmčić A, Martin N, Boor K, Wiedmann M. Pseudomonas fluorescens group bacterial strains are responsible for repeat and sporadic postpasteurization contamination and reduced fluid milk shelf life. J Dairy Sci. 2018;101:7780-7800 pubmed publisher
    ..Our data also provide important initial insights into PPC patterns (e.g., line-specific contamination), supporting the importance of molecular subtyping methods for identification of PPC sources. ..
  4. Hoelzer K, Moreno Switt A, Wiedmann M, Boor K. Emerging needs and opportunities in foodborne disease detection and prevention: From tools to people. Food Microbiol. 2018;75:65-71 pubmed publisher
    ..Moreover, WGS can help identify new sources of foodborne outbreaks and inform risk assessments, thereby providing valuable insights for risk-based policies aimed at preventing future foodborne illness. ..
  5. Buehler A, Martin N, Boor K, Wiedmann M. Psychrotolerant spore-former growth characterization for the development of a dairy spoilage predictive model. J Dairy Sci. 2018;101:6964-6981 pubmed publisher
  6. Vongkamjan K, Wiedmann M. Starting from the bench--prevention and control of foodborne and zoonotic diseases. Prev Vet Med. 2015;118:189-95 pubmed publisher
  7. Denes T, den Bakker H, Tokman J, Guldimann C, Wiedmann M. Selection and Characterization of Phage-Resistant Mutant Strains of Listeria monocytogenes Reveal Host Genes Linked to Phage Adsorption. Appl Environ Microbiol. 2015;81:4295-305 pubmed publisher
  8. Miller R, Kent D, Boor K, Martin N, Wiedmann M. Different management practices are associated with mesophilic and thermophilic spore levels in bulk tank raw milk. J Dairy Sci. 2015;98:4338-51 pubmed publisher
    ..Collectively, these results suggest that different management practices may influence mesophilic and thermophilic spore levels in raw milk. ..
  9. Miller R, Betteken M, Guo X, Altier C, Duhamel G, Wiedmann M. The Typhoid Toxin Produced by the Nontyphoidal Salmonella enterica Serotype Javiana Is Required for Induction of a DNA Damage Response In Vitro and Systemic Spread In Vivo. MBio. 2018;9: pubmed publisher
    ..Importantly, our data support that, despite having genetically similar S-CDT operons, NTS serotype S. Javiana has different genetic requirements than S. Typhi, for the production and export of active S-CDT. ..

More Information


  1. Ryan G, Roof S, Post L, Wiedmann M. Evaluation of Rapid Molecular Detection Assays for Salmonella in Challenging Food Matrices at Low Inoculation Levels and Using Difficult-to-Detect Strains. J Food Prot. 2015;78:1632-41 pubmed publisher
  2. Malley T, Butts J, Wiedmann M. Seek and destroy process: Listeria monocytogenes process controls in the ready-to-eat meat and poultry industry. J Food Prot. 2015;78:436-45 pubmed publisher
    ..Thus, a regulatory environment that encourages aggressive environmental Listeria testing is required to facilitate continued use of this science-based strategy for controlling L. monocytogenes in RTE foods. ..
  3. Trmčić A, Martin N, Boor K, Wiedmann M. A standard bacterial isolate set for research on contemporary dairy spoilage. J Dairy Sci. 2015;98:5806-17 pubmed publisher
    ..This isolate set along with publicly available isolate data provide a unique resource that will help advance knowledge of dairy-spoilage organisms as well as aid industry in development and validation of new control strategies. ..
  4. Miller R, Wiedmann M. Dynamic Duo-The Salmonella Cytolethal Distending Toxin Combines ADP-Ribosyltransferase and Nuclease Activities in a Novel Form of the Cytolethal Distending Toxin. Toxins (Basel). 2016;8: pubmed publisher
  5. Liu Y, Orsi R, Boor K, Wiedmann M, Guariglia Oropeza V. An advanced bioinformatics approach for analyzing RNA-seq data reveals sigma H-dependent regulation of competence genes in Listeria monocytogenes. BMC Genomics. 2016;17:115 pubmed publisher
  6. Orsi R, Wiedmann M. Characteristics and distribution of Listeria spp., including Listeria species newly described since 2009. Appl Microbiol Biotechnol. 2016;100:5273-87 pubmed publisher
    ..monocytogenes. This review will provide a comprehensive critical summary of our current understanding of the characteristics and distribution of the new Listeria species with a focus on Listeria sensu lato. ..
  7. Trmčić A, Chauhan K, Kent D, Ralyea R, Martin N, Boor K, et al. Coliform detection in cheese is associated with specific cheese characteristics, but no association was found with pathogen detection. J Dairy Sci. 2016;99:6105-6120 pubmed publisher
  8. Hervert C, Alles A, Martin N, Boor K, Wiedmann M. Evaluation of different methods to detect microbial hygiene indicators relevant in the dairy industry. J Dairy Sci. 2016;99:7033-7042 pubmed publisher
    ..The data obtained from this study identify differences in detection between 5 microbial hygiene indicator tests and highlight the benefits of EB and total gram-negative testing methods. ..
  9. Miller R, Wiedmann M. The Cytolethal Distending Toxin Produced by Nontyphoidal Salmonella Serotypes Javiana, Montevideo, Oranienburg, and Mississippi Induces DNA Damage in a Manner Similar to That of Serotype Typhi. MBio. 2016;7: pubmed publisher
    ..Our data suggest that infection with Salmonella strains that encode S-CDT has the potential to result in DNA damage, which may contribute to long-term sequelae. ..
  10. Miller R, Kent D, Watterson M, Boor K, Martin N, Wiedmann M. Spore populations among bulk tank raw milk and dairy powders are significantly different. J Dairy Sci. 2015;98:8492-504 pubmed publisher
    ..These data provide important insight regarding the diversity of spore populations isolated from dairy powders and bulk tank raw milk, and demonstrate that several spore genera are detected by multiple spore count methods. ..
  11. Hervert C, Martin N, Boor K, Wiedmann M. Survival and detection of coliforms, Enterobacteriaceae, and gram-negative bacteria in Greek yogurt. J Dairy Sci. 2017;100:950-960 pubmed publisher
  12. Moreno Switt A, Orsi R, den Bakker H, Vongkamjan K, Altier C, Wiedmann M. Genomic characterization provides new insight into Salmonella phage diversity. BMC Genomics. 2013;14:481 pubmed publisher
  13. Orsi R, Bowen B, Wiedmann M. Homopolymeric tracts represent a general regulatory mechanism in prokaryotes. BMC Genomics. 2010;11:102 pubmed publisher
  14. Oliver H, Orsi R, Ponnala L, Keich U, Wang W, Sun Q, et al. Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. BMC Genomics. 2009;10:641 pubmed publisher
  15. den Bakker H, Moreno Switt A, Govoni G, Cummings C, Ranieri M, Degoricija L, et al. Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica. BMC Genomics. 2011;12:425 pubmed publisher
  16. den Bakker H, Cummings C, Ferreira V, Vatta P, Orsi R, Degoricija L, et al. Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene loss. BMC Genomics. 2010;11:688 pubmed publisher
    ..This information will allow for the development of genetic and genomic criteria for pathogenic strains, including development of assays that specifically detect pathogenic Listeria strains. ..
  17. Orsi R, Borowsky M, Lauer P, Young S, Nusbaum C, Galagan J, et al. Short-term genome evolution of Listeria monocytogenes in a non-controlled environment. BMC Genomics. 2008;9:539 pubmed publisher
    ..Short-term evolution of L. monocytogenes in non-controlled environments appears to involve limited diversification beyond plasmid gain or loss and prophage diversification, highlighting the importance of phages in bacterial evolution. ..
  18. Orsi R, Sun Q, Wiedmann M. Genome-wide analyses reveal lineage specific contributions of positive selection and recombination to the evolution of Listeria monocytogenes. BMC Evol Biol. 2008;8:233 pubmed publisher
    ..Diversification of cell wall and membrane biogenesis and motility-related genes may play a particularly important role in the evolution of L. monocytogenes. ..
  19. Soyer Y, Orsi R, Rodriguez Rivera L, Sun Q, Wiedmann M. Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypes. BMC Evol Biol. 2009;9:264 pubmed publisher
  20. Weller D, Kovač J, Kent D, Roof S, Tokman J, Mudrak E, et al. Escherichia coli transfer from simulated wildlife feces to lettuce during foliar irrigation: A field study in the Northeastern United States. Food Microbiol. 2017;68:24-33 pubmed publisher
    ..These findings provide key data that may be used in future quantitative risk assessments to identify potential intervention strategies for reducing food safety risks associated with fresh produce. ..
  21. Wiedmann M, Bruce J, Keating C, Johnson A, McDonough P, Batt C. Ribotypes and virulence gene polymorphisms suggest three distinct Listeria monocytogenes lineages with differences in pathogenic potential. Infect Immun. 1997;65:2707-16 pubmed
    ..monocytogenes subspecies. None of the 20 human isolates available but 11% of our animal isolates were grouped in this lineage, indicating that strains in this lineage might have reduced virulence for humans...
  22. Trmčić A, Ralyea R, Meunier Goddik L, Donnelly C, Glass K, D AMICO D, et al. Consensus categorization of cheese based on water activity and pH-A rational approach to systemizing cheese diversity. J Dairy Sci. 2017;100:841-847 pubmed publisher
    ..g., risk to human health equivalent to pasteurized milk cheeses). ..
  23. Evanowski R, Reichler S, Kent D, Martin N, Boor K, Wiedmann M. Short communication: Pseudomonas azotoformans causes gray discoloration in HTST fluid milk. J Dairy Sci. 2017;100:7906-7909 pubmed publisher
    ..g., addition of ink) or other inadvertent chemical contamination. ..
  24. Buehler A, Evanowski R, Martin N, Boor K, Wiedmann M. Internal transcribed spacer (ITS) sequencing reveals considerable fungal diversity in dairy products. J Dairy Sci. 2017;100:8814-8825 pubmed publisher
  25. Nightingale K, Windham K, Martin K, Yeung M, Wiedmann M. Select Listeria monocytogenes subtypes commonly found in foods carry distinct nonsense mutations in inlA, leading to expression of truncated and secreted internalin A, and are associated with a reduced invasion phenotype for human intestinal epitheli. Appl Environ Microbiol. 2005;71:8764-72 pubmed publisher
    ..monocytogenes subtypes which are common among U.S. food isolates but rare among human listeriosis isolates carry inlA mutations that are associated with, and possibly at least partially responsible for, an attenuated invasion phenotype...