Affiliation: Cornell University
- Changes in cyclin-dependent kinase 2 and p27kip1 accompany glial cell differentiation of central glia-4 cellsR Tikoo
Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
J Biol Chem 272:442-7. 1997..Taken together, these results suggest that the inhibitory action of p27 upon cyclin E-CDK2 may prevent entry of cells into the S phase and regulate the progression of CG-4 cells toward an astrocytic lineage...
- Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1P Casaccia-Bonnefil
Department of Cell Biology and Anatomy, Cornell University Medical College, New York, New York 10021, USA
Genes Dev 11:2335-46. 1997..Together these data indicate a role for p27 during the decision to withdraw from the cell cycle in the oligodendrocyte lineage...