Research Topics
Genomes and GenesSpecies | Ashutosh K TewariSummaryAffiliation: Cornell University Country: USA Publications
Research Grants
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Detail Information
Publications
Improving time to continence after robot-assisted laparoscopic prostatectomy: augmentation of the total anatomic reconstruction technique by adding dynamic detrusor cuff trigonoplasty and suprapubic tube placementAshutosh K Tewari
Department of Urology, Weill Cornell Medical College of Cornell University, New York, NY, USA
J Endourol 26:1546-52. 2012..Preservation and reconstruction of the pelvic floor and supporting bladder structures leads to an earlier return of continence. These key steps need to be validated and confirmed in larger and randomized trials...
Biobanking after robotic-assisted radical prostatectomy: a quality assessment of providing prostate tissue for RNA studiesHarveer Dev
Lefrak Center of Robotic Surgery and Institute for Prostate Cancer, Brady Foundation Department of Urology, Weill Cornell Medical College, New York, NY, USA
J Transl Med 9:121. 2011..We seek to establish the integrity of our biobanking process by measuring the RNA quality of specimens derived from robotic-assisted laparoscopic radical prostatectomy...- FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing dataAndrea Sboner
Program in Computational Biology and Bioinformatics, Yale University, 300 George Street, New Haven, CT 06511, USA
Genome Biol 11:R104. 2010..It also has a module to identify exact sequences at breakpoint junctions. FusionSeq detected known and novel fusions in a specially sequenced calibration data set, including eight cancers with and without known rearrangements... 
Long-term survival in men with high grade prostate cancer: a comparison between conservative treatment, radiation therapy and radical prostatectomy--a propensity scoring approachAshutosh Tewari
Brady Urologic Health Center, New York Presbyterian Hospital and Robotic Prostatectomy and Urologic Oncology Outcomes, Weill Medical College of Cornell University, New York, New York 10021, USA
J Urol 177:911-5. 2007....- Learning curve for robotic assisted laparoscopic prostatectomy: a multi-institutional study of 3794 patientsP Sooriakumaran
Department of Urology, Weill Cornell Medical College, New York, NY, USA
Minerva Urol Nefrol 63:191-8. 2011.... - Effect of socioeconomic factors on long-term mortality in men with clinically localized prostate cancerAshutosh K Tewari
Department of Urology, Weill Medical College of Cornell University, New York, New York, USA
Urology 73:624-30. 2009..To examine the effect of socioeconomic factors on survival in black and white patients with local or regional prostate cancer... - Catheter-less robotic radical prostatectomy using a custom-made synchronous anastomotic splint and vesical urinary diversion device: report of the initial series and perioperative outcomesAshutosh Tewari
Department of Urology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
BJU Int 102:1000-4. 2008.... - Cancer control and the preservation of neurovascular tissue: how to meet competing goals during robotic radical prostatectomyAshutosh Tewari
The New York Presbyterian Hospital, Department of Urology, Weill Medical College of Cornell University, New York, NY 10021, USA
BJU Int 101:1013-8. 2008.... - Long-term survival probability in men with clinically localized prostate cancer treated either conservatively or with definitive treatment (radiotherapy or radical prostatectomy)Ashutosh Tewari
Department of Urology, New York Presbyterian Hospital, Cornell University Weill Medical College, New York, New York 10021, USA
Urology 68:1268-74. 2006..To report the long-term survival probability in more than 3000 men with localized prostate cancer treated either conservatively or by definitive treatment (radiotherapy or radical prostatectomy)... - Anatomic restoration technique of continence mechanism and preservation of puboprostatic collar: a novel modification to achieve early urinary continence in men undergoing robotic prostatectomyAshutosh K Tewari
Department of Urology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York 10021, USA
Urology 69:726-31. 2007..We propose that preservation of the puboprostatic collar during robotic surgery will help to restore early continence in men undergoing robotic prostatectomy... - The proximal neurovascular plate and the tri-zonal neural architecture around the prostate gland: importance in the athermal robotic technique of nerve-sparing prostatectomyAshutosh Tewari
Department of Urology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
BJU Int 98:314-23. 2006.... - Anatomical retro-apical technique of synchronous (posterior and anterior) urethral transection: a novel approach for ameliorating apical margin positivity during robotic radical prostatectomyAshutosh K Tewari
Lefrak Center of Robotic Surgery, James Buchanan Brady Foundation Department of Urology, Weill Cornell Medical College New York Presbyterian Hospital, New York, NY 10065, USA
BJU Int 106:1364-73. 2010.... - Assessment of required nodal yield in a high risk cohort undergoing extended pelvic lymphadenectomy in robotic-assisted radical prostatectomy and its impact on functional outcomesDaniel Sagalovich
LeFrak Center of Robotic Surgery and Institute of Prostate Cancer, James Buchanan Brady Foundation Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
BJU Int 111:85-94. 2013..To investigate the impact of an extended PLND on urinary and sexual function... - Use of a novel absorbable barbed plastic surgical suture enables a "self-cinching" technique of vesicourethral anastomosis during robot-assisted prostatectomy and improves anastomotic timesAshutosh K Tewari
LeFrak Center of Robotic Surgery and Institute of Prostate Cancer, James Buchanan Brady Foundation, Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
J Endourol 24:1645-50. 2010..To demonstrate a novel technique of self-cinching anastomosis using a barbed and looped suture during robot-assisted radical prostatectomy (RARP)... - Neuroanatomic basis for traction-free preservation of the neural hammock during athermal robotic radical prostatectomyAbhishek Srivastava
Lefrak Center of Robotic Surgery, James Buchanan Brady Foundation, Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, USA
Curr Opin Urol 21:49-59. 2011..We review the current literature evaluating the neuroanatomy of prostate and operative strategies for better preservation of sexual function... - Anatomical grades of nerve sparing: a risk-stratified approach to neural-hammock sparing during robot-assisted radical prostatectomy (RARP)Ashutosh K Tewari
LeFrak Institute of Robotic Surgery and Prostate Cancer Institute, James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York, NY 10065, USA
BJU Int 108:984-92. 2011..We also describe the surgical technique of complete hammock preservation or nerve sparing grade 1... - Visual cues as a surrogate for tactile feedback during robotic-assisted laparoscopic prostatectomy: posterolateral margin rates in 1340 consecutive patientsAshutosh K Tewari
LeFrak Center of Robotic Surgery and Institute of Prostate Cancer, James Buchanan Brady Foundation Department of Urology, Weill Medical Collage, Cornell University, 525 East 68th Street, Starr 900, New York, NY 10065, USA
BJU Int 106:528-36. 2010..e. the ability to feel when vision is greatly enhanced, as the lack of tactile feedback during RALP is often cited as a disadvantage of robotic surgery, interfering with a surgeon's ability to make intraoperative oncological decisions... - Next-generation prostate cancer biobanking: toward a processing protocol amenable for the International Cancer Genome ConsortiumRaquel Esgueva
Departments of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Diagn Mol Pathol 21:61-8. 2012.... - Robotic-assisted laparoscopic prostatectomy: a critical analysis of its impact on urinary continenceAbhishek Srivastava
Lefrak Center of Robotic Surgery and Prostate Cancer Institute, James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, NewYork, NewYork, USA
Curr Opin Urol 21:185-94. 2011..We review the current literature evaluating the technical advances to optimize continence recovery following robotic prostatectomy... - Multiphoton microscopy for structure identification in human prostate and periprostatic tissue: implications in prostate cancer surgeryAshutosh K Tewari
Lefrak Center of Robotic Surgery and Prostate Cancer Institute, James Buchanan Brady Foundation, Weill Cornell Medical College, New York, USA
BJU Int 108:1421-9. 2011..To test whether multiphoton microscopy (MPM) might allow identification of prostatic and periprostatic structures with magnification and resolution similar to gold standard histopathology... - Surgical strategies to promote early continence recovery after robotic radical prostatectomyAbhishek Srivastava
Lefrak Center of Robotic Surgery and Prostate Cancer Institute, James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, USA
Arch Esp Urol 65:529-41. 2012..We review the current literature evaluating the technical advances to optimize continence recovery following robotic prostatectomy... - Testing mutual exclusivity of ETS rearranged prostate cancerMaria A Svensson
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Lab Invest 91:404-12. 2011..In conclusion, we provide further evidence for prostate cancer tumor heterogeneity with the identification of multiple concurrent gene rearrangements... - Preservation of the puboprostatic collar and puboperineoplasty for early recovery of urinary continence after robotic prostatectomy: anatomic basis and preliminary outcomesAtsushi Takenaka
Department of Urology, Weill Medical College of Cornell University, New York City, New York, USA
Eur Urol 51:433-40; discussion 440. 2007..We reconfirm the anatomy of the periurethral supporting tissue and show the preliminary result on the early continence of patients undergoing this modification... - Real time monitoring of temperature changes in neurovascular bundles during robotic radical prostatectomy: thermal map for nerve-sparing radical prostatectomyAnil Mandhani
New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
J Endourol 22:2313-7. 2008..This study was aimed at recording real time temperature changes at the neurovascular bundle (NVB) during the use of cautery in robotic radical prostatectomy... - Clinicopathological strategies to identify contralateral prostate cancer involvement in potential candidates for focal therapySonal Grover
Weill Cornell Medical College, New York, NY, USA
Int J Surg Pathol 18:499-507. 2010..To identify the magnitude and possible predictors of contralateral lobe involvement and contralateral extraprostatic extension (EPE) in prostatic biopsy-defined localized unilateral cancers... - Epigenomic alterations in localized and advanced prostate cancerPei Chun Lin
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY Graduate Program in Biochemistry and Structural Biology, Cell and Developmental Biology, and Molecular Biology, Graduate School of Medical Sciences, Weill Cornell Medical College, New York, NY
Neoplasia 15:373-83. 2013..These results warrant clinical evaluation in larger cohorts to help distinguish indolent PCa from advanced disease... - Pathological outcomes and strategies to achieve optimal cancer control during robotic radical prostatectomy in Asian-Indian menAshutosh K Tewari
Department of Urology, Lefrak Center of Robotic Surgery and Prostate Cancer Institute, James Buchanan Brady Foundation, Weill Medical College of Cornell University, New York Presbyterian Hospital, NY, USA
Indian J Urol 27:326-30. 2011..We wanted to evaluate the oncological outcomes of Asian-Indians and Caucasians. We also derived a nomogram for prediction of extraprostatic extension (EPE) and presented biochemical recurrence (BCR) rates in the Asian-Indian population... - Future directions of robotic surgery: a case study of the Cornell athermal robotic technique of prostatectomyRobert A Leung
Weill Medical College of Cornell University, Department of Urology, New York, USA
ScientificWorldJournal 6:2553-9. 2006..We detail the experience at our institution and provide a perspective for future considerations of RRP with respect to improved preoperative imaging and surgical instrumentation... - Prostate volume and the incidence of extraprostatic extension: is there a relation?Rajiv Yadav
Department of Urology and Urologic Oncologic Outcomes, Weill Medical College of Cornell University, New York, New York 10021, USA
J Endourol 23:383-6. 2009..We investigated whether the prostate size has any association with the tumor volume and the incidence of EPE... - Double-pigtail stenting of the ureters: technique for securing the ureteral orifices during robot-assisted radical prostatectomy for large median lobesYoussef El Douaihy
LeFrak Institute of Robotic Surgery and Prostate Cancer Institute, James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10065, USA
J Endourol 23:1975-7. 2009.... - Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progressionPei Chun Lin
Departments of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Cancer Res 73:1232-44. 2013..We provide implications for epigenetic treatment and support clinical development of detecting miR-31 promoter methylation as a novel biomarker... - Antibody-based detection of ERG rearrangement-positive prostate cancerKyung Park
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
Neoplasia 12:590-8. 2010..Given the ease of performing IHC versus FISH, ERG protein expression may be useful for molecularly subtyping prostate cancer based on ERG rearrangement status and suggests clinical utility in prostate needle biopsy evaluation... - Residency training program paradigms for teaching robotic surgical skills to urology residentsSonal Grover
James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, 525 East 68th Street, Starr 900, New York, NY, 10065, USA
Curr Urol Rep 11:87-92. 2010..With the potential advantages for both patients and surgeons, we contemplate that robotic-assisted surgery may become an integral component of residency training programs in the future... - Prognostic value of insulin-like growth factor II mRNA binding protein 3 in patients treated with radical prostatectomyThomas F Chromecki
Department of Urology Division of Medical Oncology, Weill Cornell Medical College, New York, NY 10065, USA
BJU Int 110:63-8. 2012..Although IMP3 is differentially expressed in patients with features of biologically aggressive prostate cancer, it does not have independent prognostic value in patients treated with RP... - Scientific and technical advances in continence recovery following radical prostatectomyGerald Y Tan
Department of Urology, Tan Tock Seng Hospital, Singapore Department of Urology, Tan Tock Seng Hospital, Singapore
Expert Rev Med Devices 6:431-53. 2009..e., single-port or natural orifice transluminal) approaches will hopefully enable patients to derive maximal benefit from curative prostatectomy while experiencing early return of continence in the not too distant future... - Technological advances in robotic-assisted laparoscopic surgeryGerald Y Tan
Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY 10065, USA
Urol Clin North Am 36:237-49, ix. 2009.... - Role of inflammation in bladder function and interstitial cystitisSonal Grover
James Buchanan Brady Foundation Department of Urology, Weill Cornell Medical College New York Presbyterian Hospital, New York, USA
Ther Adv Urol 3:19-33. 2011..Patients who develop irreversible pathologies such as fibrosis are managed surgically, which is usually reserved for refractory cases... - Anatomical foundations and surgical manoeuvres for precise identification of the prostatovesical junction during robotic radical prostatectomyAshutosh K Tewari
Department of Urology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
BJU Int 98:833-7. 2006..To develop a technique to identify the bladder neck during robotic radical prostatectomy (RRP) using anatomical and patient studies, and to evaluate its efficacy during and after surgery... - Robot-assisted laparoscopic radical prostatectomy in the renal allograft transplant recipientJay K Jhaveri
James Buchanan Brady Foundation Department of Urology, Weill Medical College of Cornell University, New York, New York 10065, USA
J Endourol 22:2475-9. 2008..Since the advent of immunosuppressive therapy, patients have been able to lead longer lives as transplant recipients. We report the first case of robot-assisted laparoscopic prostatectomy in the renal allograft recipient... - Multiphoton microscopy of prostate and periprostatic neural tissue: a promising imaging technique for improving nerve-sparing prostatectomyRajiv Yadav
Department of Urology and Urologic Oncology Outcomes, Weill Medical College of Cornell University, New York, New York 10021, USA
J Endourol 23:861-7. 2009..The unique advantage of this technique is the acquisition of high-resolution images without necessitating any extrinsic labeling agent and with minimal phototoxic effect on tissue... - Athermal Robotic Technique of prostatectomy in patients with large prostate glands (>75 g): technique and initial resultsAssaad El-Hakim
New York Presbyterian Hospital--Weill Cornell Medical College, New York, NY, USA
BJU Int 98:47-9. 2006..CONCLUSIONS: RP for patients with large prostates is technically challenging. The robotic approach does not appear to compromise oncological control. We show the feasibility of rRP for men with large glands... - Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancerChristopher E Barbieri
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, USA
Nat Genet 44:685-9. 2012..Prostate cancers with mutant SPOP lacked ETS family gene rearrangements and showed a distinct pattern of genomic alterations. Thus, SPOP mutations may define a new molecular subtype of prostate cancer... - Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencingDorothee Pflueger
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10021, USA
Genome Res 21:56-67. 2011..Future work will focus on determining if the ETS rearrangements in prostate cancer are associated or directly predispose to a rearrangement-prone phenotype... - SLC45A3-ELK4 is a novel and frequent erythroblast transformation-specific fusion transcript in prostate cancerDavid S Rickman
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York 10021, USA
Cancer Res 69:2734-8. 2009..g., trans-splicing)... - N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancerDorothee Pflueger
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA
Neoplasia 11:804-11. 2009..Broader implications of this study support the use of RNA sequencing to discover novel cancer translocations... - Anatomical basis for carrying out a state-of-the-art radical prostatectomyAtsushi Takenaka
Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Yonago, Tottori, Japan
Int J Urol 19:7-19. 2012..Of course, these findings will also be useful for radical retropubic, perineal and conventional laparoscopic prostatectomy. Surgical anatomy should always be developing and changing with advances in surgical approaches...
Research Grants
- Real-time multiphoton microscopy of periprostatic tissue architectureAshutosh Tewari; Fiscal Year: 2009..The dynamic, high-resolution optical images achieved could empower cancer surgeons to better distinguish tissue morphology during surgery, leading to improved functional outcomes and quality of life for their patients. ..
- Real-time multiphoton microscopy of periprostatic tissue architectureAshutosh K Tewari; Fiscal Year: 2010..The dynamic, high-resolution optical images achieved could empower cancer surgeons to better distinguish tissue morphology during surgery, leading to improved functional outcomes and quality of life for their patients. ..