R K Straubinger

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi Persistence of Borrelia burgdorferi in experimentally infected dogs after antibiotic treatment
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Clin Microbiol 35:111-6. 1997
  2. ncbi Borrelia burgdorferi migrates into joint capsules and causes an up-regulation of interleukin-8 in synovial membranes of dogs experimentally infected with ticks
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 65:1273-85. 1997
  3. ncbi Borrelia burgdorferi induces the production and release of proinflammatory cytokines in canine synovial explant cultures
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 66:247-58. 1998
  4. ncbi Clinical manifestations, pathogenesis, and effect of antibiotic treatment on Lyme borreliosis in dogs
    R K Straubinger
    James A Baker Institute for Animal Health, Ithaca, New York, USA
    Wien Klin Wochenschr 110:874-81. 1998
  5. ncbi PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Clin Microbiol 38:2191-9. 2000
  6. ncbi Status of Borrelia burgdorferi infection after antibiotic treatment and the effects of corticosteroids: An experimental study
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca NY, 14853, USA
    J Infect Dis 181:1069-81. 2000
  7. ncbi Helicobacter felis infection is associated with lymphoid follicular hyperplasia and mild gastritis but normal gastric secretory function in cats
    K W Simpson
    College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 68:779-90. 2000
  8. ncbi Helicobacter pylori infection in the cat: evaluation of gastric colonization, inflammation and function
    K W Simpson
    College of Veterinary Medicine, Cornell University, Ithaca NY 14853, USA
    Helicobacter 6:1-14. 2001
  9. ncbi Histopathological studies of experimental lyme disease in the dog
    B A Summers
    Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, USA
    J Comp Pathol 133:1-13. 2005
  10. ncbi Identification of two transcripts of canine, feline, and porcine interleukin-1 alpha
    A F Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Gene 236:273-80. 1999

Collaborators

Detail Information

Publications10

  1. ncbi Persistence of Borrelia burgdorferi in experimentally infected dogs after antibiotic treatment
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Clin Microbiol 35:111-6. 1997
    ..Antibody levels in untreated infected control dogs remained high...
  2. ncbi Borrelia burgdorferi migrates into joint capsules and causes an up-regulation of interleukin-8 in synovial membranes of dogs experimentally infected with ticks
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 65:1273-85. 1997
    ..burgdorferi occurs more by migration than by blood-borne spread. From these studies employing a canine model of B. burgdorferi infection, we conclude that IL-8 is involved in the pathogenesis of acute Lyme arthritis...
  3. ncbi Borrelia burgdorferi induces the production and release of proinflammatory cytokines in canine synovial explant cultures
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 66:247-58. 1998
    ....
  4. ncbi Clinical manifestations, pathogenesis, and effect of antibiotic treatment on Lyme borreliosis in dogs
    R K Straubinger
    James A Baker Institute for Animal Health, Ithaca, New York, USA
    Wien Klin Wochenschr 110:874-81. 1998
    ..In humans, the disease primarily affects the skin, large joints, and the nervous system days to months after infection. Data generated with appropriate animal model help to understand the fundamental mechanisms of the disease...
  5. ncbi PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Clin Microbiol 38:2191-9. 2000
    ..Only 1.6% of 576 blood samples of all dogs were positive for B. burgdorferi by PCR...
  6. ncbi Status of Borrelia burgdorferi infection after antibiotic treatment and the effects of corticosteroids: An experimental study
    R K Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca NY, 14853, USA
    J Infect Dis 181:1069-81. 2000
    ..Viable spirochetes were not recovered from antibiotic-treated dogs. Two antibiotic-treated dogs showed histologic evidence of minimal lesions, whereas all control dogs had mild polyarthritis with periarteritis...
  7. ncbi Helicobacter felis infection is associated with lymphoid follicular hyperplasia and mild gastritis but normal gastric secretory function in cats
    K W Simpson
    College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 68:779-90. 2000
    ..These findings indicate that H. felis infection in cats induces lymphoid follicular hyperplasia, mild gastritis, and seroconversion, but is associated with normal gastric secretory function...
  8. ncbi Helicobacter pylori infection in the cat: evaluation of gastric colonization, inflammation and function
    K W Simpson
    College of Veterinary Medicine, Cornell University, Ithaca NY 14853, USA
    Helicobacter 6:1-14. 2001
    ..The upregulation of IL-8 in infected cats was independent of cagA and picB. Our findings argue against a direct acid-suppressing effect of H. pylori on the gastric secretory-axis in chronically infected cats...
  9. ncbi Histopathological studies of experimental lyme disease in the dog
    B A Summers
    Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, USA
    J Comp Pathol 133:1-13. 2005
    ..In 14/62 dogs, lymphoplasmacytic periarteritis and perineuritis were noted, resembling lesions found in human Lyme disease and syphilis, in which an underlying microangiopathy has been proposed...
  10. ncbi Identification of two transcripts of canine, feline, and porcine interleukin-1 alpha
    A F Straubinger
    James A Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Gene 236:273-80. 1999
    ..Expression of the two canine IL-1alpha transcripts was also detected in synovial membranes and was coordinately up-regulated in response to Borrelia burgdorferi infection under both in-vitro and in-vivo conditions...