Research Topics
| Rebecca J StoltzfusSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Iron and malaria interactions: programmatic ways forwardRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
Adv Nutr 3:579-82. 2012..To stop all iron interventions in malaria-endemic areas is an unreasonable policy option. While research findings continue to increase our understanding, there are also programmatic ways forward with the knowledge at hand...
Neonatal erythropoiesis and subsequent anemia in HIV-positive and HIV-negative Zimbabwean babies during the first year of life: a longitudinal studyMelissa F Miller
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
BMC Infect Dis 6:1. 2006..Anemia is common in HIV infection and independently associated with disease progression and mortality. The pathophysiology of HIV-related anemia is not well understood especially in infancy...- Research needed to strengthen science and programs for the control of iron deficiency and its consequences in young childrenRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Nutr 138:2542-6. 2008.... 
Iron deficiency: global prevalence and consequencesRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853, USA
Food Nutr Bull 24:S99-103. 2003..4% of the global burden. There is an urgent need to develop effective and sustainable interventions to control iron-deficiency anemia. This will likely not be achieved without substantial involvement of the private sector...- Iron interventions for women and children in low-income countriesRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Nutr 141:756S-762S. 2011..Successful implementation will require greater attention to antenatal care for pregnancy women and prioritization of iron-promoting actions (including iron supplementation and deworming) within that platform... - Iron supplementation of young children: learning from the new evidenceRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Food Nutr Bull 28:S572-84. 2007..Operations research is needed to test this. We conclude with three options for maximizing the benefits and minimizing the risks of iron supplements... - Low dose daily iron supplementation improves iron status and appetite but not anemia, whereas quarterly anthelminthic treatment improves growth, appetite and anemia in Zanzibari preschool childrenRebecca J Stoltzfus
Division of Nutritional Sciences, Cornell University, Ithaca, NY UNICEF, Zanzibar, Tanzania
J Nutr 134:348-56. 2004..We hypothesize that incident helminth infections may stimulate inflammatory immune responses in young children, with deleterious effects on protein metabolism and erythropoiesis... - Adjusting for the acute phase response is essential to interpret iron status indicators among young Zanzibari children prone to chronic malaria and helminth infectionsJacqueline K Kung'u
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Nutr 139:2124-31. 2009..Reported recent fever alone cannot be used as a marker for the APR. Either AGP or CRP is useful for adjusting if only 1 APP can be measured. However, AGP best predicted the APR in this population... - Complementary feeding messages that target cultural barriers enhance both the use of lipid-based nutrient supplements and underlying feeding practices to improve infant diets in rural ZimbabweKeriann H Paul
Division of Nutritional Sciences, Cornell University, 120 Savage Hall, Ithaca, New York 14853, USA
Matern Child Nutr 8:225-38. 2012..05). While provision of LiNS was crucial to ensure adequate intakes of iron and zinc, educational messages that were barrier-specific and delivered directly to mothers were crucial to improving the underlying diet... - Chicken thigh, chicken liver, and iron-fortified wheat flour increase iron uptake in an in vitro digestion/Caco-2 cell modelHelena Pachon
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Nutr Res 28:851-8. 2008..In the proportion of 3:1 fortified food:meat examined, meat increases the bioavailability of iron-fortified foods, but iron-fortified foods do not enhance total iron bioavailability when added to meat... - Bacterial populations in complementary foods and drinking-water in households with children aged 10-15 months in Zanzibar, TanzaniaJacqueline K Kung'u
Division of Nutritional Sciences, Cornell University, 116 Savage Hall, Ithaca, NY 14853 6301, USA
J Health Popul Nutr 27:41-52. 2009..001). It is, therefore, recommended that food safety concerns be addressed when improving complementary foods... - Beyond food insecurity: how context can improve complementary feeding interventionsKeriann H Paul
Cornell University, Ithaca, New York 14853, USA
Food Nutr Bull 32:244-53. 2011..The role of context has not been elaborated with respect to current recommendations for complementary feeding interventions, apart from a gross distinction based on food security... - Growth indices, anemia, and diet independently predict motor milestone acquisition of infants in south central NepalEmily H Siegel
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
J Nutr 135:2840-4. 2005..We conclude that growth, anemia, and diet are independently associated with delays in the onset of bipedal locomotion among young Nepali children... - Iron deficiency and physical growth predict attainment of walking but not crawling in poorly nourished Zanzibari infantsPatricia K Kariger
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
J Nutr 135:814-9. 2005..In this sample of poorly nourished infants, growth and anemia-iron status are significant predictors of walking, but not crawling... - Early helminth infections are inversely related to anemia, malnutrition, and malaria and are not associated with inflammation in 6- to 23-month-old Zanzibari childrenJacqueline K Kung'u
Cornell University, Division of Nutritional Sciences, Ithaca, New York 14853, USA
Am J Trop Med Hyg 81:1062-70. 2009..63 [95% confidence interval: 0.49, 0.81]). Non-anemic, better nourished, or non-malaria-infected children may be more exploratory of their environments and therefore increase their exposure to soil-transmitted helminths... - Homogenization, lyophilization or acid-extraction of meat products improves iron uptake from cereal-meat product combinations in an in vitro digestion/Caco-2 cell modelHelena Pachon
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Br J Nutr 101:816-21. 2009..03) in the liver-flour combination. Homogenization of beef and homogenization, lyophilization, or acid-extraction of chicken liver increases the enhancing effect of meat products on iron absorption in iron-fortified cereals... - Blood lead, anemia, and short stature are independently associated with cognitive performance in Mexican school childrenKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Nutr 134:363-71. 2004.... - New evidence of iron and zinc interplay at the enterocyte and neural tissuesKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
J Nutr 134:1295-8. 2004..We present an overview of iron and zinc absorption and function in neural tissue as one example of possible interactions... - Deficits in cognitive function and achievement in Mexican first-graders with low blood lead concentrationsKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Environ Res 100:371-86. 2006..Together with other recent findings, these results add to the empirical base of support available for evaluating the adequacy of current screening guidelines and for motivating efforts at primary prevention of childhood lead exposure... - Food chain mycotoxin exposure, gut health, and impaired growth: a conceptual frameworkLaura E Smith
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
Adv Nutr 3:526-31. 2012..We propose that future studies should address the role of mycotoxins in the pathogenesis of EE and evaluate interventions to limit mycotoxin exposure and reduce childhood stunting... - Growth in late infancy among HIV-exposed children in urban Haiti is associated with participation in a clinic-based infant feeding support interventionRebecca A Heidkamp
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
J Nutr 142:774-80. 2012..This is a promising intervention model that can be adapted and scaled-up to other HIV care contexts... - Geophagia is not associated with Trichuris or hookworm transmission in Zanzibar, TanzaniaSera L Young
Cornell University, Division of Nutritional Sciences, International Nutrition, Savage Hall, Ithaca, NY 14853, USA
Trans R Soc Trop Med Hyg 101:766-72. 2007.... - Nutrition agenda setting, policy formulation and implementation: lessons from the Mainstreaming Nutrition InitiativeDavid L Pelletier
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
Health Policy Plan 27:19-31. 2012.... - Acceptability and safety of novel infant porridges containing lyophilized meat powder and iron-fortified wheat flourHelena Pachon
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
Food Nutr Bull 28:35-46. 2007..Lyophilized meat powder with iron-fortified wheat flour can be used to produce an infant porridge with bioavailable iron, but its acceptability and safety are unknown... - Iron and zinc supplementation does not improve parent or teacher ratings of behavior in first grade Mexican children exposed to leadKatarzyna Kordas
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Pediatr 147:632-9. 2005..To determine the efficacy of iron and zinc supplementation on behavior ratings of lead-exposed children... - Alpha 1-acid glycoprotein, hepcidin, C-reactive protein, and serum ferritin are correlated in anemic schoolchildren with Schistosoma haematobiumMohamed A Ayoya
Cornell University, Ithaca, NY, USA
Am J Clin Nutr 91:1784-90. 2010..The World Health Organization and Centers for Disease Control and Prevention recommend the inclusion of indicators of iron status and inflammation in surveys assessing iron deficiency and/or anemia... - Soy- and rice-based processed complementary food increases nutrient intakes in infants and is equally acceptable with or without added milk powderKeriann H Paul
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
J Nutr 138:1963-8. 2008..However, TIPs uncovered new concerns of overconsumption and food safety. We found milk did not improve the acceptability of the soy-rice PCF and recommend TIPs as a useful tool for formative research of PCF interventions... - Effect of daily zinc supplementation on child mortality in southern Nepal: a community-based, cluster randomised, placebo-controlled trialJames M Tielsch
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 2013, USA
Lancet 370:1230-9. 2007..However, whether routine supplementation would decrease morbidity and mortality in populations with zinc deficiency is unclear. We assessed the effect of daily zinc supplementation on children in southern Nepal... - Maternal reports of sleep in 6-18 month-old infants from Nepal and Zanzibar: association with iron deficiency anemia and stuntingKatarzyna Kordas
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, United States
Early Hum Dev 84:389-98. 2008..They may also be fatigued more often, suggesting their sleep may be affected. It is unclear whether fatigue in these infants is due to poor nighttime sleep or if it is compensated for with frequent naps or longer sleep... - Young Zanzibari children with iron deficiency, iron deficiency anemia, stunting, or malaria have lower motor activity scores and spend less time in locomotionDeanna K Olney
Program in International and Community Nutrition, University of California, Davis, CA 95616, USA
J Nutr 137:2756-62. 2007.... - Interactions between nutrition and environmental exposures: effects on health outcomes in women and childrenKatarzyna Kordas
Environmental Health Department, Harvard School of Public Health, Boston, MA, USA
J Nutr 137:2794-7. 2007..The aim was to encourage nutritionists to consider environmental exposures in nutrition research. This introductory article highlights examples of nutrient-toxicant interactions... - The association between lead and micronutrient status, and children's sleep, classroom behavior, and activityKatarzyna Kordas
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
Arch Environ Occup Health 62:105-12. 2007..Anemia was linked to more off-task behaviors, lower physical activity, earlier bedtime, and shorter sleep onset. Researchers should investigate these relationships further, using more sensitive measures... - Association between anaemia during pregnancy and blood loss at and after delivery among women with vaginal births in Pemba Island, Zanzibar, TanzaniaJustine A Kavle
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
J Health Popul Nutr 26:232-40. 2008.... - Arsenic exposure and cognitive performance in Mexican schoolchildrenJorge L Rosado
School of Natural Sciences, Universidad Autonoma de Queretaro, Division of Nutritional Sciences, Queretaro, Mexico
Environ Health Perspect 115:1371-5. 2007..Previous studies have suggested an effect of high arsenic concentration on cognitive and neurobehavioral function in humans... - Unexpectedly low prevalence of Helicobacter pylori infection among pregnant women on Pemba Island, ZanzibarTamer H Farag
Department of International Health, Bloomberg School of Public Health, Johns Hopkins, University, Baltimore, MD, USA
Trans R Soc Trop Med Hyg 101:915-22. 2007..The reason for very low prevalence should be investigated further because the discovery of bacterial or dietary factors that limit infection in this population could have useful public health applications... - Is the exclusion of children under 24 months from anthelmintic treatment justifiable?Antonio Montresor
Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
Trans R Soc Trop Med Hyg 96:197-9. 2002..In light of the potential nutritional benefit achieved by regular deworming in this young age-group, the policy that excludes children aged < 24 months from treatment should be re-considered... - Performance of the Haemoglobin Colour Scale in diagnosing severe and very severe anaemiaAntonio Montresor
World Health Organization, Geneva, Switzerland
Trop Med Int Health 8:619-24. 2003.... - Low-dose daily iron supplementation for 12 months does not increase the prevalence of malarial infection or density of parasites in young Zanzibari childrenTsedal Mebrahtu
Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Nutr 134:3037-41. 2004..We conclude that in this environment of high malaria transmission, daily oral low-dose supplementation of iron for 12 mo did not affect the prevalence of malaria infection or parasite density... - Interactive effects of iron and zinc on biochemical and functional outcomes in supplementation trialsChrista Fischer Walker
Bloomberg School of Public Health, Department of International Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Clin Nutr 82:5-12. 2005..Further research is needed before health policies on joint supplementation programs can be established... - Hemoglobin and ferritin are currently the most efficient indicators of population response to iron interventions: an analysis of nine randomized controlled trialsZuguo Mei
Division of Nutrition and Physical Activity, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Nutr 135:1974-80. 2005..It is possible that the optimal indicator(s) may differ with age, sex, and pregnancy. There were too few trials in each age and sex group to allow us to explore this question... - Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trialSunil Sazawal
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
Lancet 367:133-43. 2006..However, supplementation of those who are not iron deficient might be harmful. As such, current guidelines for universal supplementation with iron and folic acid should be revised... - Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trialJames M Tielsch
Center for Human Nutrition and the Sight and Life Institute, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Baltimore, MD 21205, USA
Lancet 367:144-52. 2006..Supplementation with iron and folic acid alleviates severe anaemia and enhances neurodevelopment in deficient populations, but little is known about the risks of mortality and morbidity associated with supplementation... - Efficacy of iron and/or zinc supplementation on cognitive performance of lead-exposed Mexican schoolchildren: a randomized, placebo-controlled trialJavier Alatorre Rico
Department of Psychology, National Autonomous University of Mexico, Mexico City, Mexico
Pediatrics 117:e518-27. 2006..However, these treatments may be effective in settings with higher prevalence of nutritional deficiencies or in younger children... - Effect of maternal and neonatal vitamin A supplementation and other postnatal factors on anemia in Zimbabwean infants: a prospective, randomized studyMelissa F Miller
Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
Am J Clin Nutr 84:212-22. 2006..Anemia is prevalent in infants in developing countries. Its etiology is multifactorial and includes vitamin A deficiency... - Iron and/or zinc supplementation did not reduce blood lead concentrations in children in a randomized, placebo-controlled trialJorge L Rosado
Department of Psychology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
J Nutr 136:2378-83. 2006..Zinc supplementation did not reduce PbBs independently of zinc nutritional status. Neither iron nor zinc can be recommended as the sole treatment for lead-exposed school children... - Combined iron and folic acid supplementation with or without zinc reduces time to walking unassisted among Zanzibari infants 5- to 11-mo oldDeanna K Olney
U.S. Department of Agriculture, ARS-Western Human Nutrition Research Center, Davis, CA, USA
J Nutr 136:2427-34. 2006..There were no significant treatment effects on changes in HAZ or WAZ. The effects of treatment on time to walking may have been mediated by improvements in iron status or hemoglobin, but were not mediated through improvements in growth... - Helicobacter pylori infection is associated with severe anemia of pregnancy on Pemba Island, ZanzibarTamer H Farag
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Am J Trop Med Hyg 76:541-8. 2007..Further research is needed to establish causality because high worldwide prevalence means that even a small associated risk would be of public health significance... - A comparison of methods for detecting the eggs of Ascaris, Trichuris, and hookworm in infant stool, and the epidemiology of infection in Zanzibari infantsDavid Goodman
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Am J Trop Med Hyg 76:725-31. 2007..4%, while at 10 and 11 months of age the mean prevalence was 43.4%. Village prevalence varied from 3.6% to 43.8%. Infant geohelminth infection can occur at a high prevalence, and what method is best depends on research specifics... - Effect of zinc supplementation on mortality in children aged 1-48 months: a community-based randomised placebo-controlled trialSunil Sazawal
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Lancet 369:927-34. 2007..Our aim was to assess the effects of zinc supplementation on overall mortality in children in Pemba, Zanzibar... - Vitamin A and the nursing mother-infant dyad: evidence for interventionRebecca J Stoltzfus
Center for Human Nutrition, Department of International Health, The Johns Hopkins School of Public Health, Baltimore, MD 21205, USA
Adv Exp Med Biol 503:39-47. 2002..In sum, the probable benefits of improving the vitamin A status of the breastfeeding mother and her baby are substantial, but to achieve these benefits, more aggressive interventions will be needed... - Breastmilk erythropoietin and mother-to-child HIV transmission through breastmilkMelissa Miller
Center for Human Nutrition, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Lancet 360:1246-8. 2002..If our hypothesis is correct, EPO treatment for mother or baby, or both might help prevent transmission of HIV... - Iron and ascorbic Acid: proposed fortification levels and recommended iron compoundsSean R Lynch
Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23501, USA
J Nutr 133:2978S-84S. 2003..There is a need to develop alternative strategies for improving iron bioavailability in complementary foods because it may not be possible to preserve ascorbic acid activity in many of them... - New evidence that iron supplementation during pregnancy improves birth weight: new scientific questionsKathleen M Rasmussen
Am J Clin Nutr 78:673-4. 2003 - Total body iron in HIV-positive and HIV-negative Zimbabwean newborns strongly predicts anemia throughout infancy and is predicted by maternal hemoglobin concentrationMelissa F Miller
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21211, USA
J Nutr 133:3461-8. 2003..Babies born with low birthweight or to mothers with low hemoglobin are born with less TBI, which confers a substantially greater risk of anemia from 3 to 12 mo of age... - Short-term effects of vitamin A and antimalarial treatment on erythropoiesis in severely anemic Zanzibari preschool childrenSarah E Cusick
Center for Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Am J Clin Nutr 82:406-12. 2005..Impaired erythropoietin production is one possible mechanism. Plasmodium falciparum malaria has been found to blunt erythropoietin production, whereas vitamin A stimulates erythropoietin production in vitro... - Measuring performance: a strategy to improve programsRebecca J Stoltzfus
Center for Human Nutrition, Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205, USA
J Nutr 132:845S-8S. 2002..To be useful, evaluation findings must be disseminated, usually to multiple audiences. This requires allocation of time and resources and attention to the needs of various stakeholders...
Research Grants
- Heavy Metal Exposures in Women and Children, the Role of NutrientsRebecca Stoltzfus; Fiscal Year: 2007..The symposium will result in proceedings published in the Journal of Nutrition, one of the most widely read nutrition publications. ..