Research Topics
Species | T StokolSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Equine herpesvirus type 1 infection induces procoagulant activity in equine monocytesWee Ming Yeo
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
Vet Res 44:16. 2013..Our results indicate that EHV-1 rapidly stimulates procoagulant activity in equine monocytes in vitro. The EHV-1-induced procoagulant activity in monocytes may contribute to clinical thrombosis in horses with EHV-1 infection...
Evaluation of tissue factor expression in canine tumor cellsTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 72:1097-106. 2011..To determine whether canine tumor cell lines express functional tissue factor and shed tissue factor-containing microparticles...
Evaluation of tissue factor procoagulant activity on the surface of feline leukocytes in response to treatment with lipopolysaccharide and heat-inactivated fetal bovine serumTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA
Am J Vet Res 71:623-9. 2010..To use a chromogenic assay to measure tissue factor (TF) activity on the cell surface and in whole cell lysates of feline monocytes in response to treatment with lipopolysaccharide (LPS) and fetal bovine serum (FBS)...
Cerebrospinal fluid findings in cattle with central nervous system disorders: a retrospective study of 102 cases (1990-2008)Tracy Stokol
Department of Population Medicine, College of Veterinary Medicine, Cornell University, Ithaca, New York 14850, USA
Vet Clin Pathol 38:103-12. 2009..Cerebrospinal fluid (CSF) analysis is routinely used to aid in the diagnosis of central nervous system (CNS) disease in animals. There is little comprehensive information available on the diagnostic utility of CSF analysis in cattle...
What is your diagnosis? Pleural fluid from a neonatal Thoroughbred filly with pneumoniaTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Clin Pathol 37:237-41. 2008..The material was probably derived hematogenously and was considered an incidental finding. The pleuritis was attributed to exacerbation of the original aspiration pneumonia by the general anesthesia...
Hypercoagulability in cats with cardiomyopathyT Stokol
Department of Population Medicine and Diagnostic Sciences, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 22:546-52. 2008..Arterial thromboembolism (ATE) is a common complication of feline cardiomyopathy; however, the pathogenesis of ATE is unknown...
A comparison of platelet parameters in EDTA- and citrate-anticoagulated blood in dogsTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
Vet Clin Pathol 36:148-54. 2007..Platelet aggregates are a common artifact in canine blood. Aggregates may affect the accuracy of platelet counts, with important consequences for patient care...
Effect of hemolysis on nonesterified fatty acid and beta-hydroxybutyrate concentrations in bovine bloodTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
J Vet Diagn Invest 18:466-9. 2006..Thus, assays for measuring NEFAs should include a sample blank and NEFA results should not be interpreted in moderately to markedly hemolyzed bovine samples, because result accuracy cannot be assured...
Evaluation of latex agglutination kits for detection of fibrin(ogen) degradation products and D-dimer in healthy horses and horses with severe colicTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
Vet Clin Pathol 34:375-82. 2005..To the authors' knowledge, latex-agglutination-based plasma FDP and D-dimer assays have not been validated for use in horses...
Effect of anticoagulant and storage conditions on bovine nonesterified fatty acid and beta-hydroxybutyrate concentrations in bloodT Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Dairy Sci 88:3139-44. 2005..Our results indicated that blood for NEFA testing should be collected into EDTA or nonanticoagulant tubes (but not SST), separated promptly from cells, and maintained at 4 degrees C until analysis...
Evaluation of kits for the detection of fibrin(ogen) degradation products in dogsT Stokol
Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850 6401, USA
J Vet Intern Med 13:478-84. 1999..The plasma FDP assay is a viable alternative to currently used serum FDP assays and has the advantage of using a single (citrated plasma) sample for measuring coagulation parameters and FDP concentration...
Efficacy of fresh-frozen plasma and cryoprecipitate in dogs with von Willebrand's disease or hemophilia AT Stokol
University of Melbourne, Veterinary Clinic and Hospital, Werribee, Victoria, Australia
J Vet Intern Med 12:84-92. 1998..009). Based on its efficacy and safety, we recommend cryoprecipitate over FFP for treatment or prophylaxis of hemorrhagic episodes in dogs with vWD or hemophilia A...
Plasma D-dimer for the diagnosis of thromboembolic disorders in dogsTracy Stokol
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Schurman Hall, Upper Tower Road, Cornell University, Ithaca, NY 14853, USA
Vet Clin North Am Small Anim Pract 33:1419-35. 2003..Further studies are needed to determine the appropriate applications for this test in veterinary patients to aid in clinical decision making, treatment, and patient care...
Association between the proportion of sampled transition cows with increased nonesterified fatty acids and beta-hydroxybutyrate and disease incidence, pregnancy rate, and milk production at the herd levelP A Ospina
Department of Animal Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA
J Dairy Sci 93:3595-601. 2010..This study showed that there were detrimental herd-level effects if a large enough proportion of cows had increased metabolite concentrations, and further demonstrated that a high prevalence of herds have opportunity for improvement...
Acute pancreatitis in two five-day-old Appaloosa foalsT L Ollivett
Clinical Sciences, Cornell University, New York, USA
Equine Vet J Suppl 44:96-9. 2012..Severe acute pancreatitis should be included as a differential in an acutely ill foal with diarrhoea, colic, cerebral cortica dysfunction and hyperlipaemia...
Associations of elevated nonesterified fatty acids and beta-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the northeastern United StatesP A Ospina
Department of Animal Science, College of Agriculture and Life Sciences, Ithaca, NY 14853, USA
J Dairy Sci 93:1596-603. 2010..With the exception of milk production in heifers, this study indicates that increased concentrations of serum NEFA and BHBA had a detrimental effect on reproductive performance and milk production...
Evaluation of nonesterified fatty acids and beta-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseasesP A Ospina
Department of Animal Science, College of Agriculture and Life Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Dairy Sci 93:546-54. 2010....
Induction of interleukin-4 production in neonatal IgE+ cells after crosslinking of maternal IgEBettina Wagner
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Dev Comp Immunol 34:436-44. 2010..In conclusion, stimulation via maternal IgE antibodies mediated innate IL-4 production in neonatal basophils which might provide a paragenetic mechanism to promote the development of adaptive T-cell responses in the neonate after birth...
Anticoagulant-dependent in vitro hemagglutination in a catDeanna M W Schaefer
Departments of Population Medicine and Diagnostic Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA
Vet Clin Pathol 38:194-200. 2009..The phenomenon needs to be recognized as an in vitro occurrence in order to prevent erroneous diagnosis of immune-mediated hemolytic anemia...
Intestinal lymphoma of granular lymphocytes in a fisher (Martes pennanti) and a Eurasian otter (Lutra lutra)Susan L Bartlett
Section of Wildlife Health, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
J Zoo Wildl Med 41:309-15. 2010..To the authors' knowledge, this is the first report of lymphoma of granular lymphocytes in a fisher and a Eurasian otter...
Concentrated bone marrow aspirate improves full-thickness cartilage repair compared with microfracture in the equine modelLisa A Fortier
Departments of Clinical Sciences, VMC C3 181, Cornell University, Ithaca, NY 14853, USA
J Bone Joint Surg Am 92:1927-37. 2010....
Evaluation of exercise-induced changes in concentrations of C-reactive protein and serum biochemical values in sled dogs completing a long-distance endurance raceJoseph J Wakshlag
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University Ithaca, NY 14853, USA
Am J Vet Res 71:1207-13. 2010....
Brucella canis endophthalmitis in 3 dogs: clinical features, diagnosis, and treatmentEric C Ledbetter
Cornell University, College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY 14853, USA
Vet Ophthalmol 12:183-91. 2009..To describe historical, clinical and diagnostic features of dogs with Brucella canis endophthalmitis and the response to medical therapy...
Clinical efficacy and safety of recombinant canine erythropoietin in dogs with anemia of chronic renal failure and dogs with recombinant human erythropoietin-induced red cell aplasiaJohn E Randolph
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 18:81-91. 2004..Unfortunately, rcEPO was not as effective in restoring erythrocyte production in dogs that had previously developed rhEPO-induced red cell aplasia...
Transferrin receptor expression in canine lymphomaH Priest
Cornell University, College of Veterinary Medicine, Ithaca, NY 14853, USA
Vet Pathol 48:466-74. 2011....
Expression, bioactivity, and clinical assessment of recombinant feline erythropoietinJohn E Randolph
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 65:1355-66. 2004..Unfortunately, development of RCA during treatment with CHO cell-derived recombinant erythropoietin proteins was not eliminated as a serious safety concern, even for this feline-specific preparation...
Fell Pony syndrome in a pony in North AmericaRachel B Gardner
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 20:198-203. 2006
Influence of treatment with ultralow-dose aspirin on platelet aggregation as measured by whole blood impedance aggregometry and platelet P-selectin expression in clinically normal dogsKristopher S Sharpe
Department of Clinical Sciences, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 71:1294-304. 2010..To evaluate the influence of treatment with ultralow-dose aspirin (ULDAsp) on platelet aggregation, P-selectin (CD62P) expression, and formation of platelet-leukocyte aggregates in clinically normal dogs...
Stage migration in dogs with lymphomaAndrea B Flory
Departments of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
J Vet Intern Med 21:1041-7. 2007..As more sensitive staging methods are introduced, dogs are reclassified as having a higher disease stage, thereby affecting comparisons of dogs across differently staged clinical trials, and possibly, prognosis...
Acute pancreatitis in two five-day-old Appaloosa foalsT L Ollivett
Clinical Sciences, Cornell University, New York, USA Clemson Veterinary Diagnostic Center, Clemson University, South Carolina, USA Population Medicine and Diagnostic Sciences, Cornell University, New York, USA Department of Medicine and Epidemiology, University of California Davis, California, USA Department of Biomedical Sciences, Tufts Cummings School of Veterinary Medicine, Massachusetts, USA
Equine Vet J 44:96-9. 2012..Severe acute pancreatitis should be included as a differential in an acutely ill foal with diarrhoea, colic, cerebral cortical dysfunction and hyperlipaemia...
Hematologic, serum biochemical, and cortisol changes associated with anticipation of exercise and short duration high-intensity exercise in sled dogsCraig T Angle
College of Veterinary Medicine, Auburn University, Auburn, AL, USA
Vet Clin Pathol 38:370-4. 2009..These changes have been attributed to the duration and intensity of exercise. However, inconsistencies in the timing of collection of resting blood samples can be a confounding variable when interpreting results...
Clinical and clinicopathologic features of dogs that consumed foodborne hepatotoxic aflatoxins: 72 cases (2005-2006)Diane M Dereszynski
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Am Vet Med Assoc 232:1329-37. 2008..To characterize clinical signs, clinicopathologic features, treatments, and survival in dogs with naturally acquired foodborne aflatoxicosis...
Evaluation of a bladder tumor antigen test as a screening test for transitional cell carcinoma of the lower urinary tract in dogsCarolyn J Henry
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 64:1017-20. 2003..The test performed slightly better on centrifuged urine samples than on uncentrifuged urine samples. CONCLUSIONS AND CLINICAL RELEVANCE: Our results indicate that the V-BTA test is useful in screening for urinary tract TCC in dogs...
What is your diagnosis? Biopsy impression smear of a hepatic mass in a yearling Thoroughbred fillyJenifer R Gold
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
Vet Clin Pathol 37:339-43. 2008..To our knowledge, this report is the first to document secondary erythrocytosis with increased erythropoietin concentration in a horse with hepatoblastoma, and also the first to describe the cytopathologic features of this rare tumor...
Use of a centrifugation-based, point-of-care device for production of canine autologous bone marrow and platelet concentratesMichael S Thoesen
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 67:1655-61. 2006..9%). CONCLUSIONS AND CLINICAL RELEVANCE: Bone marrow-derived cell and platelet-rich concentrates may form bone if delivered in an engineered graft, thus decreasing the need for cancellous bone grafts...
Intracerebral plasma cell tumor in a cat: a case report and literature reviewMarc J Greenberg
Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
J Vet Intern Med 18:581-5. 2004
Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic miceXu Peng
Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Cardiovasc Res 64:421-30. 2004..However, the functions of focal adhesion kinase in endothelial cell (EC) in vivo remain unclear. This study aims to examine the role of FAK in EC function and angiogenesis in vivo by transgenic mice approach...
Serum iron and plasma fibrinogen concentrations as indicators of systemic inflammatory diseases in horsesAlexandre S Borges
From the Department of Veterinary Clinical Science, Sao Paulo State University, UNESP, FMVZ Botucatu SP, Brazil
J Vet Intern Med 21:489-94. 2007..Detection of systemic inflammation, which is important for proper diagnosis and prompt treatment, can be challenging...
Diagnosis of DIC in cats: is it time to go back to the basics?Tracy Stokol
J Vet Intern Med 20:1289-90. 2006
