Research Topics
Genomes and Genes | Leah H SomervilleSummaryAffiliation: Cornell University Country: USA Publications
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Detail Information
Publications
Human bed nucleus of the stria terminalis indexes hypervigilant threat monitoringLeah H Somerville
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire, USA
Biol Psychiatry 68:416-24. 2010....
Frontostriatal maturation predicts cognitive control failure to appetitive cues in adolescentsLeah H Somerville
Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, 1300 York Avenue, Box 140, New York, NY 10065, USA
J Cogn Neurosci 23:2123-34. 2011..Biased responding in this system is one possible mechanism underlying heightened risk-taking during adolescence...
A time of change: behavioral and neural correlates of adolescent sensitivity to appetitive and aversive environmental cuesLeah H Somerville
Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, New York, NY 10065, USA
Brain Cogn 72:124-33. 2010..Finally, we discuss other influences that may contribute to exaggerated reward and emotion processing associated with adolescence, including hormonal fluctuations and the role of the social environment...
Developmental neurobiology of cognitive control and motivational systemsLeah H Somerville
Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, NY, USA
Curr Opin Neurobiol 20:236-41. 2010....
The storm and stress of adolescence: insights from human imaging and mouse geneticsB J Casey
Sackler Institute for Developmental Psychobiology, Weil Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA
Dev Psychobiol 52:225-35. 2010..Together, these studies provide a converging methods approach for understanding the highly variable stress and turmoil experienced in adolescence...
Behavioral and neural properties of social reinforcement learningRebecca M Jones
Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, New York, New York 10065, USA
J Neurosci 31:13039-45. 2011..This work highlights the fundamental influence of acceptance by one's peers in altering subsequent behavior...
A genetic variant BDNF polymorphism alters extinction learning in both mouse and humanFatima Soliman
The Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, New York, NY 10065, USA
Science 327:863-6. 2010..Thus, this variant BDNF allele may play a role in anxiety disorders showing impaired learning of cues that signal safety versus threat and in the efficacy of treatments that rely on extinction mechanisms, such as exposure therapy...
A tale of two negatives: differential memory modulation by threat-related facial expressionsF Caroline Davis
Department of Psychological and Brain Sciences, Dartmouth College, Durham, NC, USA
Emotion 11:647-55. 2011..Because these effects cannot be attributed to differences in arousal or valence processing, we suggest they are best understood in terms of differences in the predictive information conveyed by fearful and angry facial expressions...
A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorderPaul J Whalen
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
Biol Psychiatry 63:858-63. 2008..Here, we sought to determine whether pretreatment amygdala and rostral ACC (rACC) reactivity to facial expressions could predict treatment outcomes in patients with generalized anxiety disorder (GAD)...
Behavioral and neural representation of emotional facial expressions across the lifespanLeah H Somerville
Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, New York 10065, USA
Dev Neuropsychol 36:408-28. 2011..Recent neuroimaging work has tested amygdala and prefrontal engagement in experimental paradigms mimicking real aspects of social interactions, which we highlight briefly, along with considerations for future research...
Self-esteem modulates medial prefrontal cortical responses to evaluative social feedbackLeah H Somerville
Department of Psychological and Brain Sciences, Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Cereb Cortex 20:3005-13. 2010..Taken together, the present findings propose a functional role for the vACC/mPFC in representing the salience of social feedback and shaping perceptions of relative social standing...
Behavioral and neural correlates of delay of gratification 40 years laterB J Casey
Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, New York, NY 10065, USA
Proc Natl Acad Sci U S A 108:14998-5003. 2011....
Interactions between transient and sustained neural signals support the generation and regulation of anxious emotionLeah H Somerville
Sackler Institute for Developmental Psychobiology, Weill Cornell Medical College, New York, NY 10044, USA
Cereb Cortex 23:49-60. 2013....
Anterior cingulate cortex responds differentially to expectancy violation and social rejectionLeah H Somerville
Department of Psychological and Brain Sciences and Center for Cognitive Neuroscience, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Neurosci 9:1007-8. 2006..The results demonstrate that the dorsal ACC is sensitive to expectancy violations, whereas the ventral ACC is differentially responsive to social feedback...
