Marcus B Smolka

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc The many roads to checkpoint activation
    Patrice Y Ohouo
    Cornell University Ithaca, NY USA
    Cell Cycle 11:4495. 2012
  2. pmc The checkpoint transcriptional response: make sure to turn it off once you are satisfied
    Marcus B Smolka
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA
    Cell Cycle 11:3166-74. 2012
  3. pmc DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9
    Patrice Y Ohouo
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, USA
    Nature 493:120-4. 2013
  4. pmc Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes
    Francisco M Bastos de Oliveira
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA
    EMBO J 31:1798-810. 2012
  5. pmc Interactome analysis reveals ezrin can adopt multiple conformational states
    Raghuvir Viswanatha
    From the Department of Molecular Biology and Genetics and Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853
    J Biol Chem 288:35437-51. 2013
  6. doi request reprint DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response
    Patrice Y Ohouo
    Graduate Program in Biochemistry, Molecular and Cell Biology, Weill Institute for Cell and Molecular Biology, Cornell University, 339 Weill Hall, Ithaca, New York 14853 7202, USA
    Mol Cell 39:300-6. 2010
  7. doi request reprint TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor
    Jason A MacGurn
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA
    Cell 147:1104-17. 2011
  8. pmc Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells
    Raghuvir Viswanatha
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA
    J Cell Biol 199:969-84. 2012

Collaborators

  • Scott D Emr
  • Yi Liu
  • Patrice Y Ohouo
  • Raghuvir Viswanatha
  • Francisco M Bastos de Oliveira
  • Anthony Bretscher
  • Jason A MacGurn
  • Jessica Wayt
  • Chu Jian Ma
  • Robertus A M de Bruin
  • Michael R Harris
  • Pijus Brazauskas
  • Pi Chiang Hsu
  • Beatriz S Almeida

Detail Information

Publications8

  1. pmc The many roads to checkpoint activation
    Patrice Y Ohouo
    Cornell University Ithaca, NY USA
    Cell Cycle 11:4495. 2012
    ..Comment on: Wang G, et al. Cell Cycle 2012; 11:3792-800...
  2. pmc The checkpoint transcriptional response: make sure to turn it off once you are satisfied
    Marcus B Smolka
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA
    Cell Cycle 11:3166-74. 2012
    ....
  3. pmc DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9
    Patrice Y Ohouo
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853, USA
    Nature 493:120-4. 2013
    ..Our findings show that DDC signalling is monitored and modulated through the direct action of DNA-repair factors...
  4. pmc Linking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes
    Francisco M Bastos de Oliveira
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, USA
    EMBO J 31:1798-810. 2012
    ..Our results reveal that replication stress induces expression of G1/S genes via the Rad53-MBF pathway and that an SBF-to-MBF switch characterizes a new class of genes that can be induced by replication stress...
  5. pmc Interactome analysis reveals ezrin can adopt multiple conformational states
    Raghuvir Viswanatha
    From the Department of Molecular Biology and Genetics and Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York 14853
    J Biol Chem 288:35437-51. 2013
    ..Taken together, the data indicate that ezrin can exist in three different conformational states, and different ligands "perceive" ezrin conformational states differently. ..
  6. doi request reprint DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response
    Patrice Y Ohouo
    Graduate Program in Biochemistry, Molecular and Cell Biology, Weill Institute for Cell and Molecular Biology, Cornell University, 339 Weill Hall, Ithaca, New York 14853 7202, USA
    Mol Cell 39:300-6. 2010
    ..Our results unveil how Mec1 regulates the Slx4 and Rtt107 scaffolds and establish a mechanistic link between DNA damage signaling and fork repair...
  7. doi request reprint TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor
    Jason A MacGurn
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA
    Cell 147:1104-17. 2011
    ....
  8. pmc Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells
    Raghuvir Viswanatha
    Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA
    J Cell Biol 199:969-84. 2012
    ..Thus, the domain-specific presence of microvilli is a dynamic process requiring a localized kinase driving the phosphocycling of ezrin to continually bias its function to the apical membrane...