J G Scott

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Cytochromes P450 and insecticide resistance
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853, USA
    Insect Biochem Mol Biol 29:757-77. 1999
  2. ncbi request reprint The nicotinic acetylcholine receptor subunits Mdalpha5 and Mdbeta3 on autosome 1 of Musca domestica are not involved in spinosad resistance
    J R Gao
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853, USA
    Insect Mol Biol 16:691-701. 2007
  3. ncbi request reprint House-fly cytochrome P450 CYP6D1: 5' flanking sequences and comparison of alleles
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901
    Gene 226:347-53. 1999
  4. doi request reprint Transcriptional diversity and allelic variation in nicotinic acetylcholine receptor subunits of the red flour beetle, Tribolium castaneum
    F D Rinkevich
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901, USA
    Insect Mol Biol 18:233-42. 2009
  5. doi request reprint Use of isogenic strains indicates CYP9M10 is linked to permethrin resistance in Culex pipiens quinquefasciatus
    M C Hardstone
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853 0901, USA
    Insect Mol Biol 19:717-26. 2010
  6. ncbi request reprint Increased transcription of CYP6D1 causes cytochrome P450-mediated insecticide resistance in house fly
    N Liu
    Department of Entomology, Cornell University, Ithaca, New York 14853 0901, USA
    Insect Biochem Mol Biol 28:531-5. 1998
  7. ncbi request reprint Cytochrome P450s CYP6D3 and CYP6D1 are part of a P450 gene cluster on autosome 1 in the house fly
    S Kasai
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, New York 14853 0901, USA
    Insect Mol Biol 10:191-6. 2001
  8. ncbi request reprint Cloning of two novel P450 cDNAs from German cockroaches, Blattella germanica (L.): CYP6K1 and CYP6J1
    Z Wen
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853-0901, USA
    Insect Mol Biol 10:131-7. 2001
  9. ncbi request reprint Insect cytochromes P450: diversity, insecticide resistance and tolerance to plant toxins
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901, USA
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 121:147-55. 1998
  10. ncbi request reprint CYP9E2, CYP4C21 and related pseudogenes from German cockroaches, Blattella germanica: implications for molecular evolution, expression studies and nomenclature of P450s
    Z Wen
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853-0901, USA
    Gene 272:257-66. 2001

Collaborators

  • N Liu
  • L Zhang
  • L C Harrington
  • J Gao
  • X Huang
  • A G Clark
  • S Kasai
  • M C Hardstone
  • F D Rinkevich
  • R L Hamm
  • Z Wen
  • G G H Lin
  • I M Scott
  • P E Kaufman
  • T Kozaki
  • T Tomita
  • O Komagata
  • B P Lazzaro
  • S G Brady
  • H Jensen
  • B J R Philogene
  • M B Isman
  • J T Arnason
  • C E Horak
  • D A Rutz
  • G D Wheelock

Detail Information

Publications25

  1. ncbi request reprint Cytochromes P450 and insecticide resistance
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853, USA
    Insect Biochem Mol Biol 29:757-77. 1999
    ..The importance of these studies for development of effective insecticide resistance management strategies is discussed...
  2. ncbi request reprint The nicotinic acetylcholine receptor subunits Mdalpha5 and Mdbeta3 on autosome 1 of Musca domestica are not involved in spinosad resistance
    J R Gao
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853, USA
    Insect Mol Biol 16:691-701. 2007
    ..This suggests neither Mdalpha5 nor Mdbeta3 is responsible for spinosad resistance in house flies...
  3. ncbi request reprint House-fly cytochrome P450 CYP6D1: 5' flanking sequences and comparison of alleles
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901
    Gene 226:347-53. 1999
    ..The possible roles of these sequence differences in regulation of CYP6D1 expression are discussed...
  4. doi request reprint Transcriptional diversity and allelic variation in nicotinic acetylcholine receptor subunits of the red flour beetle, Tribolium castaneum
    F D Rinkevich
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901, USA
    Insect Mol Biol 18:233-42. 2009
    ..Alleles were found for all subunit genes, except Tcasalpha1 and Tcasalpha10. Transcriptional and allelic diversity are discussed with respect to receptor function and potential interactions with insecticides...
  5. doi request reprint Use of isogenic strains indicates CYP9M10 is linked to permethrin resistance in Culex pipiens quinquefasciatus
    M C Hardstone
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853 0901, USA
    Insect Mol Biol 19:717-26. 2010
    ..We conclude that CYP9M10 is linked to permethrin resistance in these strains of C. p. quinquefasciatus, and is likely to be the P450 gene responsible for resistance in these strains...
  6. ncbi request reprint Increased transcription of CYP6D1 causes cytochrome P450-mediated insecticide resistance in house fly
    N Liu
    Department of Entomology, Cornell University, Ithaca, New York 14853 0901, USA
    Insect Biochem Mol Biol 28:531-5. 1998
    ..The increased rate of transcription of CYP6D1 in the resistant strain (LPR) is controlled by two factors: one on autosome 1 and another on autosome 2...
  7. ncbi request reprint Cytochrome P450s CYP6D3 and CYP6D1 are part of a P450 gene cluster on autosome 1 in the house fly
    S Kasai
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, New York 14853 0901, USA
    Insect Mol Biol 10:191-6. 2001
    ..3 kDa. The CYP6D3 protein is most similar to house fly CYP6D1 (78%) and Cyp6D2 (56%) from Drosophila melanogaster. The deduced amino acid sequences of CYP6D3 and CYP6D1 are identical at the Helix I and heme binding regions...
  8. ncbi request reprint Cloning of two novel P450 cDNAs from German cockroaches, Blattella germanica (L.): CYP6K1 and CYP6J1
    Z Wen
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853-0901, USA
    Insect Mol Biol 10:131-7. 2001
    ..Southern blots suggest the two mRNA bands detected in the Northern blot might be a result of alternative splicing. No signal could be detected at any life stage using the CYP6J1 probe, suggesting that CYP6J1 was expressed at a low level...
  9. ncbi request reprint Insect cytochromes P450: diversity, insecticide resistance and tolerance to plant toxins
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901, USA
    Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 121:147-55. 1998
    ..Advances in this area are critical because they will provide important new information about insect physiology, biochemistry and development...
  10. ncbi request reprint CYP9E2, CYP4C21 and related pseudogenes from German cockroaches, Blattella germanica: implications for molecular evolution, expression studies and nomenclature of P450s
    Z Wen
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853-0901, USA
    Gene 272:257-66. 2001
    ..The relative number of P450 pseudogenes in B. germanica is apparently higher than in D. melanogaster. The implications of these results for the molecular evolution, expression studies and nomenclature of P450s are discussed...
  11. ncbi request reprint A house fly gene homologous to the zinc finger proto-oncogene Gfi-1
    S Kasai
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, New York, 14853-0901, USA
    Biochem Biophys Res Commun 283:644-7. 2001
    ..Given that Gfi-1 is highly conserved from insects to vertebrates suggests this may be an important transcription factor in many taxa...
  12. ncbi request reprint Frequencies of the pyrethroid resistance alleles of Vssc1 and CYP6D1 in house flies from the eastern United States
    F D Rinkevich
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, New York 14853 0901, USA
    Insect Mol Biol 15:157-67. 2006
    ..Based on this analysis it appears the kdr-his mutation had multiple evolutionary origins, but that the kdr mutation may have had a single origin. The impacts of these findings on resistance management are discussed...
  13. ncbi request reprint Expression and regulation of CYP6D3 in the house fly, Musca domestica (L.)
    S Kasai
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853-0901, USA
    Insect Biochem Mol Biol 32:1-8. 2001
    ..6 fold) strains. The CYP6D3 5' flanking regions were sequenced from the resistant and susceptible strains. Possible regulatory sequences within this region are discussed...
  14. ncbi request reprint Cytochromes P450 of insects: the tip of the iceberg
    J G Scott
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, New York, USA
    Pest Manag Sci 57:958-67. 2001
    ..Our knowledge continues to expand at a rapid pace, suggesting that the next decade will outpace the last in terms of improving our understanding of the cytochromes P450 of insects...
  15. ncbi request reprint Monitoring insecticide resistance in house flies (Diptera: Muscidae) from New York dairies
    P E Kaufman
    Department of Entomology, Cornell University, Ithaca, New York 14853 0999, USA
    Pest Manag Sci 57:514-21. 2001
    ..A diagnostic concentration for each insecticide is proposed on the basis of a comparison of our bioassays...
  16. ncbi request reprint The nicotinic acetylcholine receptor subunit Mdalpha6 from Musca domestica is diversified via post-transcriptional modification
    J R Gao
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853, USA
    Insect Mol Biol 16:325-34. 2007
    ..These comparisons indicate that Mdalpha6 is not responsible for spinosad resistance in house flies...
  17. ncbi request reprint Differences in development, glycogen, and lipid content associated with cytochrome P450-mediated permethrin resistance in Culex pipiens quinquefasciatus (Diptera: Culicidae)
    M C Hardstone
    Department of Entomology, Cornell University, Ithaca, NY 14853, USA
    J Med Entomol 47:188-98. 2010
    ....
  18. ncbi request reprint Anti-P450lpr antiserum inhibits specific monooxygenase activities in LPR house fly microsomes
    G D Wheelock
    Department of Entomology, Cornell University, Ithaca, New York 14853
    J Exp Zool 264:153-8. 1992
    ..These results demonstrate that methoxyresourfin-O-demethylase activity and benzo(a)pyrene hydroxylase activity are characteristic substrates for P450lpr activity in the LPR strain of house fly...
  19. ncbi request reprint Inhibitors of CYP6D1 in house fly microsomes
    J G Scott
    Department of Entomology, Cornell University, Ithaca, NY 14853 0901, USA
    Insect Biochem Mol Biol 26:645-9. 1996
    ..Isosafrole was shown to be a potent synergist of pyrethroid insecticides in adult house flies...
  20. pmc Hormone receptor-like in 96 and Broad-Complex modulate phenobarbital induced transcription of cytochrome P450 CYP6D1 in Drosophila S2 cells
    G G H Lin
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853, USA
    Insect Mol Biol 20:87-95. 2011
    ..This represents new functional evidence that Drosophila HR96 and BR-C can act as an activator and repressor, respectively, in regulating PB induced transcription in insects...
  21. ncbi request reprint A high frequency of male determining factors in male Musca domestica (Diptera: Muscidae) from Ipswich, Australia
    R L Hamm
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853, USA
    J Med Entomol 46:169-72. 2009
    ..The high frequency of M, the presence of M on four different linkage groups, and the large number of male genotypes found in this population make it unique relative to other populations of house flies that have been examined...
  22. ncbi request reprint A case for sequencing the genome of Musca domestica (Diptera: Muscidae)
    J G Scott
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 14853, USA
    J Med Entomol 46:175-82. 2009
    ..The community of researchers investigating Musca domestica are well prepared and highly motivated to apply genomic analyses to their widely varied research programs...
  23. ncbi request reprint Use of quantitative real-time polymerase chain reaction to estimate the size of the house-fly Musca domestica genome
    J Gao
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY 17853 0901, USA
    Insect Mol Biol 15:835-7. 2006
    ....
  24. ncbi request reprint The house fly aliesterase gene (MdalphaE7) is not associated with insecticide resistance or P450 expression in three strains of house fly
    J G Scott
    Department of Entomology, Comstock Hall, Cornell University, Ithaca, NY, USA
    Insect Biochem Mol Biol 33:139-44. 2003
    ..The relationship between MdalphaE7 alleles and insecticide resistance is discussed in light of these findings...
  25. ncbi request reprint Botanical insecticides for controlling agricultural pests: piperamides and the Colorado Potato Beetle Leptinotarsa decemlineata say (Coleoptera: Chrysomelidae)
    I M Scott
    Biology Department, University of Ottawa, Ottawa, Ontario, Canada
    Arch Insect Biochem Physiol 54:212-25. 2003
    ..1%. There is also potential for Piper extracts to control insecticide resistant populations in conjunction with other integrated pest management (IPM) strategies used in conventional and organic agriculture...