Research Topics
| THEODORE SCHWARTZSummaryAffiliation: Cornell University Country: USA Publications
Research Grants
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Detail Information
Publications
Three-dimensional endoscopic pituitary surgeryAbtin Tabaee
Department of Otolaryngology Head and Neck Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York 10065, USA
Neurosurgery 64:288-93; discussion 294-5. 2009..We describe a novel 3-dimensional (3-D) stereoendoscope and discuss our early experience using it to provide improved depth perception during transsphenoidal pituitary surgery...- Standardization of amygdalohippocampectomy with intraoperative magnetic resonance imaging: preliminary experienceTheodore H Schwartz
Department of Neurosurgery, The Neurological Institute of New Jersey, UMDNJ New Jersey Medical School, Newark, NJ, U S A
Epilepsia 43:430-6. 2002.... - Endoscopic cranial base surgery: classification of operative approachesTheodore H Schwartz
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
Neurosurgery 62:991-1002; discussion 1002-5. 2008..Indications for surgery are not well defined. Our objective was to create a comprehensive classification system of the various approaches and describe their indications with case examples... - Late seizures in patients initially seizure free after epilepsy surgeryTheodore H Schwartz
Neurological Surgery, Weill Cornell Medical College, and New York Presbyterian Hospital, New York, NY 10021, USA
Epilepsia 47:567-73. 2006..No published reports document the rate and predictors of late recurrence in a large series of patients undergoing surgery in the magnetic resonance imaging (MRI) era... - Endoscopic transsphenoidal pituitary surgery with intraoperative magnetic resonance imagingTheodore H Schwartz
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
Neurosurgery 58:ONS44-51; discussion ONS44-51. 2006..Each provides improved visualization of intra- and parasellar anatomy with the goal of attaining a complete resection. The combination of the two techniques has not been previously reported in the literature... - The application of optical recording of intrinsic signals to simultaneously acquire functional, pathological and localizing information and its potential role in neurosurgeryTheodore H Schwartz
Max Planck Institut fur Neurobiologie, Martinsried Munchen, Deutschland
Stereotact Funct Neurosurg 83:36-44. 2005..We explored methods of simultaneously representing localizing information, functional architecture and the border of an epileptic focus in vivo with intrinsic signal imaging... - Intraoperative optical imaging of human face cortical topography: a case studyTheodore H Schwartz
Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA
Neuroreport 15:1527-31. 2004..This study demonstrates that intrinsic signal imaging can be performed on humans during operative procedures with sufficient spatial resolution to reveal high-resolution topographic maps... - Quadrigeminal non-aneurysmal subarachnoid hemorrhage--a true variant of perimesencephalic subarachnoid hemorrhage. Case reportTheodore H Schwartz
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, 525 East 68th, Box 99, New York, NY 10021, USA
Clin Neurol Neurosurg 105:95-8. 2003..We propose that the more common pretruncal PNSH and less common quadrigeminal PNSH are two types of perimesencephalic SAH with separate, distinct etiologies, both of which have a more benign clinical course than aneurysmal SAH... - Optical imaging of epileptiform events in visual cortex in response to patterned photic stimulationTheodore H Schwartz
Max Planck Institute für Neurobiologie, 82152 Martinsried, Germany
Cereb Cortex 13:1287-98. 2003..Thus, optical imaging of intrinsic signals can be used to simultaneously map epilepsy and normal functional anatomy with high spatial resolution... - Blood volume and hemoglobin oxygenation response following electrical stimulation of human cortexMinah Suh
Department of Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, 525 East 68th St, Box #99, New York, NY 10021, USA
Neuroimage 31:66-75. 2006.... - Focal increases in perfusion and decreases in hemoglobin oxygenation precede seizure onset in spontaneous human epilepsyMingrui Zhao
Department of Neurosurgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, 525 East 68th Street, New York, NY 10021, U S A
Epilepsia 48:2059-67. 2007..We report such a rare opportunity in a man with recurrent focal epilepsy arising from a cavernous malformation... - Intrinsic optical signal imaging of neocortical seizures: the 'epileptic dip'Sonya Bahar
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA
Neuroreport 17:499-503. 2006..This persistent ictal ischemia was confirmed by direct measurement of tissue oxygenation using oxygen-sensitive electrodes... - Recent developments in oximetry and perfusion-based mapping techniques and their role in the surgical treatment of neocortical epilepsySaadat Shariff
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10021, USA
Epilepsy Behav 8:363-75. 2006..Likewise, a diffuse decrease in deoxygenated hemoglobin, related to the blood oxygen level-dependent signal recorded with functional magnetic resonance imaging, spread to adjacent gyri and was poorly localized... - The importance of latency in the focality of perfusion and oxygenation changes associated with triggered afterdischarges in human cortexHongtao Ma
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10065, USA
J Cereb Blood Flow Metab 29:1003-14. 2009.... - 10 pearls for safe endoscopic skull base surgeryMadeleine R Schaberg
Department of Otolaryngology, Weill Medical College of Cornell University, New York Presbyterian Hospital, 1305 York Avenue, Fifth Floor, New York, NY 10065, USA
Otolaryngol Clin North Am 43:945-54. 2010..This article presents the 10 most important tenets that have proved useful to the authors regarding postoperative patient management and surgical practice... - Microscopic versus endoscopic transnasal pituitary surgeryMadeleine R Schaberg
Department of Otolaryngology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York 10021, USA
Curr Opin Otolaryngol Head Neck Surg 18:8-14. 2010..In the present article, we will analyze the current literature on outcomes between the two techniques... - Staying within the lines: the formation of visuospatial boundaries influences multisensory feature integrationIan C Fiebelkorn
Program in Cognitive Neuroscience, Department of Psychology, The City College of the City University of New York, 138th Street and Convent Avenue, New York, NY 10031, USA
Eur J Neurosci 31:1737-43. 2010.... - Spatiotemporal dynamics of perfusion and oximetry during ictal discharges in the rat neocortexMingrui Zhao
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
J Neurosci 29:2814-23. 2009..Possible mechanisms based on recent astrocyte-based models of neurovascular coupling are discussed... - Hemodynamic surrogates for excitatory membrane potential change during interictal epileptiform events in rat neocortexHongtao Ma
Dept of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY 10065, USA
J Neurophysiol 101:2550-62. 2009..Our data suggest that hemodynamic signals can accurately define the spatial extent of excitatory interictal epileptiform subthreshold membrane activity at specific time points in their evolution... - Transcavum interforniceal endoscopic surgery of the third ventricleMark M Souweidane
Department of Neurological Surgery, Weill Medical College of Cornell University and Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
J Neurosurg Pediatr 2:231-6. 2008..Given the common occurrence of cavum septum pellucidum (CSP) and cavum vergae (CV), the endoscopic surgeon should be familiar with that particular anatomy especially as it pertains to surgery within the third ventricle... - Role of perioperative antibiotics in endoscopic skull base surgerySeth M Brown
Department of Otorhinolaryngology, Weill Medical College of Cornell University, New York, New York 10021, USA
Laryngoscope 117:1528-32. 2007.... - Endoscopic endonasal transsphenoidal surgery for growth hormone-secreting pituitary adenomasChristoph P Hofstetter
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
Neurosurg Focus 29:E6. 2010..The aim of this study was to determine the preoperative predictors of the extent of resection and endocrinological remission following endonasal endoscopic removal of growth hormone (GH)-secreting pituitary adenomas... - The role of dose escalation with intracavitary brachytherapy in the treatment of localized CNS malignancies: outcomes and toxicities of a prospective studyA Gabriella Wernicke
Department of Stich Radiation Oncology, Weill Cornell University School of Medicine, 525 East 68th Street, New York, NY 10065, USA
Brachytherapy 9:91-9. 2010..We now report mature results of this trial, its outcomes, and a toxicity profile... - Predictors of short-term outcomes following endoscopic pituitary surgeryAbtin Tabaee
Department of Otolaryngology, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10003, USA
Clin Neurol Neurosurg 111:119-22. 2009..Refinement of endoscopic pituitary surgery requires an understanding of the impact of demographic and surgical variables on outcomes... - Temporal dependence in uncoupling of blood volume and oxygenation during interictal epileptiform events in rat neocortexMinah Suh
Department of Neurological Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
J Neurosci 25:68-77. 2005..quot;.. - Monitoring the effects of BCNU chemotherapy Wafers (Gliadel) in glioblastoma multiforme with proton magnetic resonance spectroscopic imaging at 3.0 TeslaJonathan P Dyke
Department of Radiology, Citigroup Biomedical Imaging Center, Weill Cornell Medical College, New York, NY 10021, USA
J Neurooncol 82:103-10. 2007..Additional study of patients receiving Gliadel Wafers using (1)H MRSI may serve to aid clinicians in assessing tumor regression and gauging efficacy of this chemotherapy treatment... - Endoscopic transphenoidal pituitary surgery with real-time intraoperative magnetic resonance imagingVijay K Anand
Department of Otolaryngology and Head and Neck Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York, USA
Am J Rhinol 20:401-5. 2006.... - Neurovascular coupling and oximetry during epileptic eventsMinah Suh
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA
Mol Neurobiol 33:181-97. 2006.... - Intrinsic optical signal imaging of normal and abnormal physiology in animals and humans--seeing the invisibleMinah Suh
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA
Clin Neurosurg 52:135-49. 2005 - Dexmedetomidine and neurocognitive testing in awake craniotomyPatricia Fogarty Mack
Weill Medical College of Cornell University, New York, New York 10021, USA
J Neurosurg Anesthesiol 16:20-5. 2004..Dexmedetomidine appears to be a useful sedative for awake craniotomy when sophisticated neurologic testing is required... - Janus flap: bilateral nasoseptal flaps for anterior skull base reconstructionGurston G Nyquist
Department of Otorhinolaryngology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY, USA
Otolaryngol Head Neck Surg 142:327-31. 2010..The purpose of this study is to describe the first experiences with bilateral nasoseptal flaps for reconstruction of very large skull base defects... - "Gasket-seal" watertight closure in minimal-access endoscopic cranial base surgeryLewis Z Leng
Department of Neurosurgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York, USA
Neurosurgery 62:ONSE342-3; discussion ONSE343. 2008..Postoperative cerebrospinal fluid leak remains a persistent challenge. A new method for watertight closure of the anterior cranial base is presented... - Feasibility and safety of GliaSite brachytherapy in treatment of CNS tumors following neurosurgical resectionA Gabriella Wernicke
Radiation Oncology, Weil Cornell University School of Medicine, New York, NY, USA
J Cancer Res Ther 6:65-74. 2010..To investigate feasibility and safety of GliaSite brachytherapy for treatment of central nervous system (CNS) tumors following neurosurgical resection. We report mature results of long-term follow-up, outcomes and toxicity... - Bilateral intracranial electrodes for lateralizing intractable epilepsy: efficacy, risk, and outcomeDimitris G Placantonakis
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
Neurosurgery 66:274-83. 2010..We describe the indications, risks, and utility of such bilateral surveys at our institution... - Three-dimensional and 2-dimensional endoscopic exposure of midline cranial base targets using expanded endonasal and transcranial approachesJonathan Roth
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
Neurosurgery 65:1116-28; discussion 1128-30. 2009..To integrate these approaches into neurosurgical practice, the extent of their anatomic exposure must be compared with that provided by more traditional transcranial approaches... - Endoscopic endonasal repair of anterior skull base non-traumatic cerebrospinal fluid leaks, meningoceles, and encephalocelesGurston G Nyquist
Department of Otorhinolaryngology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
J Neurosurg 113:961-6. 2010.... - Endoscopic, endonasal extended transsphenoidal, transplanum transtuberculum approach for resection of suprasellar lesionsIlya Laufer
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
J Neurosurg 106:400-6. 2007..The authors report on a series of purely endoscopic endonasal surgeries for resection of suprasellar supradiaphragmatic lesions above a normal-sized sella turcica with a low risk of CSF leakage... - Algorithm for reconstruction after endoscopic pituitary and skull base surgeryAbtin Tabaee
Department of Otolaryngology Head and Neck Surgery, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, New York, USA
Laryngoscope 117:1133-7. 2007..The technique and outcomes of endoscopic skull base reconstruction remain incompletely described in the literature... - The endoscopic endonasal transsphenoidal approach to the suprasellar cisternTheodore H Schwartz
Department of Neurological Surgery, Weill Cornell Medical College, New York, New York, USA
Clin Neurosurg 54:226-35. 2007 - Surgical treatment of epilepsy in adults and childrenDean Barone
Division of Neurosurgery, Robert Wood Johnson Medical Center, New Brunswick, NJ, USA
JAAPA 16:29-30, 33-5. 2003 - Endoscopic endonasal transethmoidal transcribriform transfovea ethmoidalis approach to the anterior cranial fossa and skull baseJeffrey P Greenfield
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
Neurosurgery 66:883-92; discussion 892. 2010..An alternate and more direct approach is the endonasal, transethmoidal, transcribriform, transfovea ethmoidalis approach... - Frameless stereotactic placement of depth electrodes in epilepsy surgeryAshesh D Mehta
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York 10021, USA
J Neurosurg 102:1040-5. 2005..The laterotemporal approach is a more accurate method of placing electrodes than is the occipitotemporal one, likely due to the increased distance from the entry point to the target... - Novel low-grade glioneuronal neoplasm presenting in an octogenarian: case report and review of the literatureYu-Hung Kuo
Department of Neurological Sciences, Weill Cornell Medical College, New York-Presbyterian Hospital, 525 E. 68th Street, Box #99, New York, NY 10021, USA
Clin Neurol Neurosurg 108:426-32. 2006..They are histopathologically quite heterogeneous, and in this report we present a novel subtype. Radiographically, these lesions can mimic more aggressive primary brain tumors... - Endoscopic endonasal transclival resection of chordomas: operative technique, clinical outcome, and review of the literatureJustin F Fraser
Department of Neurosurgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York, USA
J Neurosurg 112:1061-9. 2010..For certain chordomas, the endonasal endoscopic transclival approach is a novel minimal access, but it is an equally aggressive alternative providing the most direct route to the tumor epicenter... - Endoscopic management of spontaneous meningoencephalocele of the lateral sphenoid sinusAbtin Tabaee
Department of Otolaryngology Head and Neck Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York, USA
J Neurosurg 112:1070-7. 2010..The objective of this paper is to report the theoretical etiology, surgical technique, and outcomes in patients undergoing endoscopic repair of spontaneous meningoencephalocele of the sphenoid sinus... - Catheter placement for Ommaya reservoirs with frameless surgical navigation: technical noteJeffrey P Greenfield
Department of Neurological Surgery, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, NY 10021, USA
Stereotact Funct Neurosurg 86:101-5. 2008..We assessed the safety and precision of using frameless surgical navigation for the placement of Ommaya reservoir catheters... - Endonasal endoscopic resection of the odontoid process in a nonachondroplastic dwarf with juvenile rheumatoid arthritis: feasibility of the approach and utility of the intraoperative Iso-C three-dimensional navigation. Case reportIlya Laufer
Department of Neurological Surgery and, 2 Otolaryngology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
J Neurosurg Spine 8:376-80. 2008..The patient subsequently underwent an endoscopic transnasal resection of the dens with assistance of Iso-C navigation. He recovered well and tolerated regular diet on postoperative Day 2... - Stereotactic minimally invasive tubular retractor system for deep brain lesionsJeffrey P Greenfield
Department of Neurological Surgery, Weill Cornell Medical Center, New York Presbyterian Hospital, New York, New York, USA
Neurosurgery 63:334-9; discussion 339-40. 2008..Although a commercially available frame-based tubular retractor system is on the market (COMPASS; Compass, Inc., Rochester, MN), we modified existing off-the-shelf equipment at our institution into a frameless tubular brain retractor... - Localization in epilepsyDimitris G Placantonakis
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY 10065, USA
Neurol Clin 27:1015-30. 2009..Invasive electroencephalography remains the gold standard for identifying epileptic foci and guiding the surgeon to successful resections... - Three-dimensional endoscopic sinus surgery: feasibility and technical aspectsSeth M Brown
Department of Otolaryngology Head and Neck Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY, USA
Otolaryngol Head Neck Surg 138:400-2. 2008 - Endoscopic pituitary surgery: a systematic review and meta-analysisAbtin Tabaee
Department of Otolaryngology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY 10003, USA
J Neurosurg 111:545-54. 2009..Published reports are limited by small sample size and nonrandomized study design. A meta-analysis allows for a description of the impact of endoscopic surgery on short-term outcomes... - Endonasal endoscopic resection of an os odontoideum to decompress the cervicomedullary junction: a minimal access surgical techniqueLewis Z Leng
Department of Neurosurgery, Weill Cornell Medical College, NY Presbyterian Hospital, New York, NY, USA
Spine (Phila Pa 1976) 34:E139-43. 2009..We report the case of a 50 year-old woman with os odontoideum and posterior atlantoaxial subluxation, who underwent an occipitocervical fusion followed by endonasal endoscopic anterior decompression of the cervicomedullary junction (CMJ)... - Intrathecal fluorescein in endoscopic skull base surgeryAbtin Tabaee
Department of Otolaryngology Head and Neck Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, NY 10002, USA
Otolaryngol Head Neck Surg 137:316-20. 2007..The impact on outcomes of CSF visualization with intrathecal fluorescein, however, is unknown... - Endoscopic biopsy sampling of tophaceous gout of the odontoid process. Case report and review of the literatureJustin F Fraser
Department of Neurological Surgery, Weill Medical Center of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
J Neurosurg Spine 7:61-4. 2007..With the aid of transoral or transnasal endoscopic biopsy sampling, the diagnosis can be reached in a minimally invasive manner... - Long-term expansion of adult human brain subventricular zone precursorsAngel Ayuso-Sacido
Laboratory for Translational Stem Cell Research, Department of Neurological Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
Neurosurgery 62:223-9; discussion 229-31. 2008..This article details our ability to reliably harvest, isolate, characterize, and maintain normal adult human brain SVZ precursor cells... - Intracranial nasal natural killer/T-cell lymphoma: immunopathologically-confirmed case and review of literatureNeal Luther
Department of Neurological Surgery, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA
J Neurooncol 75:185-8. 2005..Although rare, CNS invasion portends a poor prognosis, emphasizing the importance of early and accurate immunophenotype profiling and the need for novel, aggressive therapy... - Palliative endoscopic surgery in advanced sinonasal and anterior skull base neoplasmsAbtin Tabaee
Department of Otolaryngology Head and Neck Surgery, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY, USA
Otolaryngol Head Neck Surg 142:126-8. 2010..To explore the role of endoscopic surgery for palliative intent in patients with advanced sinonasal and anterior skull base neoplasms... - The endoscopic, endonasal, transmaxillary transpterygoid approach to the pterygopalatine fossa, infratemporal fossa, petrous apex, and the Meckel caveChristoph P Hofstetter
Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
J Neurosurg 113:967-74. 2010.... - Endoscopic endonasal minimal access approach to the clivus: case series and technical nuancesJustin F Fraser
Department of Neurosurgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York 10065, USA
Neurosurgery 67:ons150-8; discussion ons158. 2010..The endoscopic endonasal transclival approach is a novel minimal-access method of managing clival pathology. Limited cases have been published... - Safety of low-dose intrathecal fluorescein in endoscopic cranial base surgeryDimitris G Placantonakis
Department of Neurological Surgery, Weill Medical College of Cornell University, New York Presbyterian Hospital, New York, New York 10021, USA
Neurosurgery 61:161-5; discussion 165-6. 2007..However, complications have been reported with various doses and the technique has fallen out of favor. We explored the safety of low-dose intrathecal fluorescein administered to patients undergoing endoscopic cranial base surgery... - Evidence of cerebral reorganization following perinatal stroke demonstrated with fMRI and DTI tractographySamantha L Heller
Weill Cornell Medical College, United States
Clin Imaging 29:283-7. 2005..Functional data were overlaid onto 3D diffusion tensor tractography, providing a unique image of the right hemisphere language recruitment... - Audio-visual multisensory integration in superior parietal lobule revealed by human intracranial recordingsSophie Molholm
Cognitive Neurophysiology Lab, Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Inst for Psychiatric Research, 140 Old Orangeburg Rd, Orangeburg, NY 10962, USA
J Neurophysiol 96:721-9. 2006..These results are discussed in the context of the role of SPL in supramodal spatial attention and sensory-motor transformations... - Neurosurgical management of medically intractable epilepsy associated with hypomelanosis of ItoDimitris G Placantonakis
Epilepsia 46:329-31. 2005 - A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processingPejman Sehatpour
Cognitive Neurophysiology Laboratory, Program in Cognitive Neuroscience and Schizophrenia, Nathan S Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
Proc Natl Acad Sci U S A 105:4399-404. 2008..The results indicate that transient beta-band oscillatory coupling between these three distributed cortical regions may reflect a mechanism for effective communication during visual object processing...
Research Grants
- Optical imaging of epilepsy in rat and human neocortexTHEODORE SCHWARTZ; Fiscal Year: 2007..These experiments will set the groundwork for implementing optical recordings in general clinical practice as a novel technique for mapping and predicting human seizures. ..