Research Topics
| BRUCE SCHACKMANSummaryAffiliation: Cornell University Country: USA Publications
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Publications
The lifetime cost of current human immunodeficiency virus care in the United StatesBruce R Schackman
Department of Public Health, Weill Medical College of Cornell University, New York, New York 10021, USA
Med Care 44:990-7. 2006..We sought to project the lifetime cost of medical care for human immunodefiency virus (HIV)-infected adults using current antiretroviral therapy (ART) standards...
Cost-effectiveness of pre-exposure prophylaxis for HIV: a reviewBruce R Schackman
Weill Cornell Medical College, New York, New York, USA
Curr Opin HIV AIDS 7:587-92. 2012..This review examines six recent studies of the cost-effectiveness of PrEP for preventing HIV transmission in the USA and South Africa...
The cost-effectiveness of rapid HIV testing in substance abuse treatment: Results of a randomized trialBruce R Schackman
Department of Public Health, Weill Cornell Medical College, 402 East 67th Street, New York, NY 10065, United States Electronic address
Drug Alcohol Depend 128:90-7. 2013..Fewer than half of US community-based substance abuse treatment programs make HIV testing available on-site or through referral...
Cost-effectiveness of long-term outpatient buprenorphine-naloxone treatment for opioid dependence in primary careBruce R Schackman
Department of Public Health, Weill Cornell Medical College, 402 East 67th Street, New York, NY 10065, USA
J Gen Intern Med 27:669-76. 2012..Bup/nx is off patent but not available as a generic...
Cost-effectiveness of rapid syphilis screening in prenatal HIV testing programs in HaitiBruce R Schackman
Department of Public Health, Weill Medical College, Cornell University, New York, New York, United States of America
PLoS Med 4:e183. 2007..We compared the cost-effectiveness, projected health outcomes, and annual cost of screening pregnant women using a rapid syphilis test as part of scaled-up prenatal testing to prevent mother-to-child HIV transmission in Haiti...
Quality-of-life tradeoffs for hepatitis C treatment: do patients and providers agree?Bruce R Schackman
Department of Public Health, Weill Medical College of Cornell University, New York, NY 10021, USA
Med Decis Making 28:233-42. 2008..Subjects completed rating scale and standard gamble evaluations of current health and hypothetical descriptions of HCV symptoms and treatment side effects on a scale from 0 (death or worse than death) to 1 (best possible health)...
Overcoming policy and financing barriers to integrated buprenorphine and HIV primary careBruce R Schackman
Department of Public Health, Weill Medical College of Cornell University, New York, NY 10021, USA
Clin Infect Dis 43:S247-53. 2006....
Racial differences in virologic failure associated with adherence and quality of life on efavirenz-containing regimens for initial HIV therapy: results of ACTG A5095Bruce R Schackman
Department of Public Health, Weill Medical College, New York, NY 10021, USA
J Acquir Immune Defic Syndr 46:547-54. 2007..We rigorously examined associations over time among race, virologic failure, 4 self-reported adherence metrics, and quality of life (QOL)...
Budget impact of Medicaid Section 1115 demonstrations for early HIV treatmentBruce R Schackman
Weill Medical College of Cornell University, New York, NY 10021, USA
Health Care Financ Rev 26:67-80. 2005....
Does higher cost mean better quality? evidence from highly-regarded adolescent drug treatment programsBruce R Schackman
Department of Public Health, Weill Cornell Medical College, 411 East 69th Street New York, NY 10021, USA
Subst Abuse Treat Prev Policy 2:23. 2007....
Offers of hepatitis C care do not lead to treatmentBruce R Schackman
Department of Public Health, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
J Urban Health 84:455-8. 2007..Whereas offers of HCV treatment may be increasing, there is a need to improve continuity of care, patient-provider communication, and patient education regarding HCV treatment options for treatment rates to improve...
Sexually active HIV-positive patients frequently report never using condoms in audio computer-assisted self-interviews conducted at routine clinical visitsBruce R Schackman
Department of Public Health, Weill Cornell Medical College, New York, New York 10021, USA
AIDS Patient Care STDS 22:123-9. 2008..ACASI interviews may be an effective way of identifying patients in clinical settings who require prevention counseling as well as other psychosocial services...
Comparison of health state utilities using community and patient preference weights derived from a survey of patients with HIV/AIDSBruce R Schackman
Center for Risk Analysis, Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts, USA
Med Decis Making 22:27-38. 2002....
The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIVBruce R Schackman
Department of Public Health, Weill Cornell Medical College, New York, New York 10021, USA
AIDS 22:2025-33. 2008..To evaluate the clinical impact and cost-effectiveness of HLA-B*5701 testing to guide selection of first-line HIV regimens in the United States...
Potential risks and benefits of HIV treatment simplification: a simulation model of a proposed clinical trialBruce R Schackman
Department of Public Health, Weill Cornell Medical College, New York, NY 10021, USA
Clin Infect Dis 45:1062-70. 2007..We projected the long-term outcomes of this treatment simplification strategy to inform the design of a proposed multicenter, randomized clinical trial...
Cost-effectiveness implications of the timing of antiretroviral therapy in HIV-infected adultsBruce R Schackman
Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA
Arch Intern Med 162:2478-86. 2002....
How often do sensitivity analyses for economic parameters change cost-utility analysis conclusions?Bruce R Schackman
Division of Outcomes and Effectiveness Research, Department of Public Health, Weill Medical College of Cornell University, New York 10021, USA
Pharmacoeconomics 22:293-300. 2004..Sensitivity analyses for health-related QOL (HR-QOL), cost and discount rate economic parameters are of particular interest because they measure the effects of methodological and estimation uncertainties...
The cost-effectiveness of elective Cesarean delivery to prevent hepatitis C transmission in HIV-coinfected womenBruce R Schackman
Divisions of Outcomes and Effectiveness, Department of Public Health, Weill Medical College of Cornell University, New York, NY 10021, USA
AIDS 18:1827-34. 2004....
The cost of integrated HIV care and buprenorphine/naloxone treatment: results of a cross-site evaluationBruce R Schackman
Department of Public Health, Weill Cornell Medical College, New York, NY 10065, USA
J Acquir Immune Defic Syndr 56:S76-82. 2011..Implementing integrated HIV and buprenorphine/naloxone treatment requires cost estimates to plan and obtain funding...
Implementation science for the prevention and treatment of HIV/AIDSBruce R Schackman
Department of Public Health, Weill Cornell Medical College, New York, NY 10065, USA
J Acquir Immune Defic Syndr 55:S27-31. 2010....
The cost of HIV medication adherence support interventions: results of a cross-site evaluationB R Schackman
Weill Medical College of Cornell University, New York, USA
AIDS Care 17:927-37. 2005..Payers should consider enhanced reimbursement for adherence support services...
Feasibility of using audio computer-assisted self-interview (ACASI) screening in routine HIV careBruce R Schackman
Department of Public Health, Weill Cornell Medical College, New York, NY, USA
AIDS Care 21:992-9. 2009..ACASI screening should be considered in HIV clinical care settings to assist providers in identifying patients with the greatest need for targeted psychosocial services including adherence support and depression care...
Design issues in initial HIV-treatment trials: focus on ACTG A5095Heather J Ribaudo
Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard School of Public Health, Boston, USA
Antivir Ther 11:751-60. 2006..We also hope to inform the field regarding issues in choosing composite versus virological endpoints as well as other key considerations in trial design and monitoring...
Efavirenz-based regimens in treatment-naive patients with a range of pretreatment HIV-1 RNA levels and CD4 cell countsHeather J Ribaudo
Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
J Infect Dis 197:1006-10. 2008..There were no significant differences among subgroups with respect to treatment responses. These results demonstrate the potency of efavirenz-containing regimens across a spectrum of pretreatment VLs and CD4 counts...
Can urban methadone patients complete health utility assessments?Paul A Teixeira
Division of Health Policy, Department of Public Health, Weill Medical College of Cornell University, New York, NY 10021, USA
Patient Educ Couns 71:302-7. 2008..An estimated 65-90% of MMT patients are chronically infected with HCV...
Clinical impact and cost of monitoring for asymptomatic laboratory abnormalities among patients receiving antiretroviral therapy in a resource-poor settingSerena P Koenig
Division of Global Health Equity, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Clin Infect Dis 51:600-8. 2010..Laboratory monitoring for toxicity among patients receiving antiretroviral therapy (ART) in less-developed settings is technically challenging and consumes significant resources...
Cost-effectiveness of tenofovir as first-line antiretroviral therapy in IndiaMelissa A Bender
Divisions of General Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
Clin Infect Dis 50:416-25. 2010..We evaluated the clinical outcomes and cost-effectiveness of first-line ART using tenofovir in India, compared with current practice using stavudine or zidovudine...
Cost-effectiveness of an intervention to improve adherence to antiretroviral therapy in HIV-infected patientsKenneth A Freedberg
Divisions of General Medicine and Infectious Diseases and the Partners AIDS Research Center, Massachusetts General Hospital, Boston, MA 02114, USA
J Acquir Immune Defic Syndr 43:S113-8. 2006..Adherence interventions with modest effectiveness are likely to provide long-term survival benefit to patients and to be cost-effective compared with other uses of HIV care funds...
Achieving effective antidepressant pharmacotherapy in primary care: the role of depression care management in treating late-life depressionYuhua Bao
Division of Health Policy, Department of Public Health, Weill Cornell Medical College, New York, NewYork, USA
J Am Geriatr Soc 57:895-900. 2009..To estimate the effect of an evidence-based depression care management (DCM) intervention on the initiation and appropriate use of antidepressant in primary care patients with late-life depression...
Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infectionRoy M Gulick
Weill Medical College of Cornell University, New York, USA
N Engl J Med 350:1850-61. 2004....
A cost-benefit analysis of external hip protectors in the nursing home settingLisa A Honkanen
Division of Geriatrics and Gerontology, Joan and Sanford Weill Medical College, Cornell University, New York, New York 10021, USA
J Am Geriatr Soc 53:190-7. 2005..To estimate potential cost savings generated by a program of hip protectors in the nursing home from a Medicare perspective...
Test and treat DC: forecasting the impact of a comprehensive HIV strategy in Washington DCRochelle P Walensky
Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Clin Infect Dis 51:392-400. 2010..We forecast outcomes of this approach if implemented in Washington DC...
Cost effectiveness of pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 before irinotecan administration for metastatic colorectal cancerHeather Taffet Gold
Department of Public Health, Weill Cornell Medical College, New York, NY, USA
Cancer 115:3858-67. 2009....
Three- vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trialRoy M Gulick
Cornell HIV Clinical Trials Unit, Division of International Medicine and Infectious Diseases, Weill Medical College of Cornell University, New York, NY, USA
JAMA 296:769-81. 2006..Three-drug antiretroviral regimens are standard of care for initial treatment of human immunodeficiency virus 1 (HIV-1) infection, but a 4-drug regimen could improve antiretroviral activity and be more effective than a 3-drug regimen...
Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppressionRoy M Gulick
Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
AIDS 21:813-23. 2007..To compare a quadruple-nucleoside with an efavirenz-containing regimen for treatment of HIV-1 infection...
Can hip protector use cost-effectively prevent fractures in community-dwelling geriatric populations?Lisa A Honkanen
Division of Geriatrics and Gerontology, Weill Medical College of Cornell University, New York, NY 10021, USA
J Am Geriatr Soc 54:1658-65. 2006..To estimate the cost-effectiveness from a societal perspective of a hip protector (HP) program over the remaining lifetime of individuals initially living at home...
Variation in orthopaedic surgeons' perceptions about the indications for rotator cuff surgeryWarren R Dunn
The Hospital for Special Surgery, 525 East 70th Street, New York, NY 10021, USA
J Bone Joint Surg Am 87:1978-84. 2005..The purpose of the current study was to characterize orthopaedic surgeons' attitudes concerning medical decision-making about rotator cuff surgery and to investigate the associations between these beliefs and reported surgical volumes...
A synthesis of cost-utility analysis literature in infectious diseasePatricia W Stone
Columbia University School of Nursing, New York, NY 10032, USA
Lancet Infect Dis 5:383-91. 2005..The results of cost-utility analyses have important implications for the development of clinical guidelines and resource allocation decisions. More trained investigators and better peer-review processes are needed...
Response to commentary by Dr. Oliver and colleagues on hip protectorsLisa A Honkanen
J Am Geriatr Soc 54:1159-60. 2006
Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjectsDaniel R Kuritzkes
Brigham and Women s Hospital, Harvard Medical School, Cambridge, MA 02139, USA
J Infect Dis 197:867-70. 2008..27 [95% confidence interval], 1.15-4.49; P = .018). These results support resistance testing before starting antiretroviral therapy...
The quality of highly regarded adolescent substance abuse treatment programs: results of an in-depth national surveyRosalind Brannigan
Drug Strategies, 1755 Massachusetts Avenue NW, Washington, DC 20036 2103, USA
Arch Pediatr Adolesc Med 158:904-9. 2004..Drug and alcohol abuse and dependence are the most prevalent causes of adolescent morbidity and mortality in the United States. Effective, accessible treatment for adolescents with substance abuse problems is urgently needed...
Expanded HIV screening in the United States: effect on clinical outcomes, HIV transmission, and costsA David Paltiel
Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Connecticut 06520 8034, USA
Ann Intern Med 145:797-806. 2006..An extensive literature supports expanded HIV screening in the United States. However, the question of whom to test and how frequently remains controversial...
Variations in self-rated health among patients with HIV infectionJoseph M Mrus
Health Services Research and Development, Cincinnati VA Medical Center, Cincinnati, OH, USA
Qual Life Res 15:503-14. 2006....
The survival benefits of AIDS treatment in the United StatesRochelle P Walensky
Division of Infectious Disease and General Medicine, Massachusetts General Hospital, Boston 02114, USA
J Infect Dis 194:11-9. 2006..As widespread adoption of potent combination antiretroviral therapy (ART) reaches its tenth year, our objective was to quantify the cumulative survival benefits of acquired immunodeficiency syndrome (AIDS) care in the United States...
The use of an educational video during informed consent in an HIV clinical trial in HaitiPatrice Joseph
Groupe Haitien d'Etude du Sarcome de Kaposi et des Infections Opportunistes, GHESKIO, Port au Prince, Haiti
J Acquir Immune Defic Syndr 42:588-91. 2006..CONCLUSIONS: Informed consent using an educational video ensured good comprehension in most of the volunteers. Additional educational sessions may be necessary for some participants with lower educational level...
Preventing vertical hepatitis C virus transmissionBruce R Schackman
Clin Infect Dis 45:802. 2007
Research Grants
- HCV Treatment Cost-Effectiveness in 3 IDU PopulationsBRUCE SCHACKMAN; Fiscal Year: 2007..This work will provide insight into important policy questions identified by the NIH Consensus Development Conference on the Management of Hepatitis C in June 2002 and will inform development of treatment and reimbursement guidelines. ..
- Economic Analysis of Rapid HIV and HCV Testing in Drug Abuse Treatment ProgramsBRUCE SCHACKMAN; Fiscal Year: 2009....
- Economic Analysis of Rapid HIV and HCV Testing in Drug Abuse Treatment ProgramsBruce R Schackman; Fiscal Year: 2010....
