Research Topics
| Francesco RubinoSummaryAffiliation: Cornell University Country: USA Publications
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Detail Information
Publications
Is type 2 diabetes an operable intestinal disease? A provocative yet reasonable hypothesisFrancesco Rubino
Department of Surgery, Catholic University of Rome, Rome, Italy
Diabetes Care 31:S290-6. 2008..This article presents available evidence in support of the hypothesis that type 2 diabetes may be an operable disease characterized by a component of intestinal dysfunction...
The Diabetes Surgery Summit consensus conference: recommendations for the evaluation and use of gastrointestinal surgery to treat type 2 diabetes mellitusFrancesco Rubino
Department of Surgery, Section of Metabolic Surgery, Weill Cornell Medical College New York Presbyterian Hospital, New York, NY, USA
Ann Surg 251:399-405. 2010..To develop guidelines for the use of gastrointestinal surgery to treat type 2 diabetes and to craft an agenda for further research...
Metabolic surgery to treat type 2 diabetes: clinical outcomes and mechanisms of actionFrancesco Rubino
Weill Cornell Medical College New York Presbyterian Hospital, New York, New York, USA
Annu Rev Med 61:393-411. 2010....
Metabolic surgery: the role of the gastrointestinal tract in diabetes mellitusFrancesco Rubino
Section of Gastrointestinal Metabolic Surgery, Department of Surgery, Weill Cornell Medical College New York Presbyterian Hospital, 525 East 68th Street, P 714, New York, NY 10065, USA
Nat Rev Endocrinol 6:102-9. 2010..In light of the evidence presented here, we speculate that the gastrointestinal tract might have a role in the pathophysiology of T2DM and obesity...
Medical versus surgical treatment of type 2 diabetes: the search for level 1 evidenceAlpana P Shukla
Section of Gastrointestinal Metabolic Surgery, Department of Surgery, Weill Cornell Medical Center, New York Presbyterian Hospital, New York, New York 10065, USA
Surg Obes Relat Dis 8:476-82. 2012..The aim of this consortium is to standardize research in T2DM surgery and timely accumulate homogeneous data that can help assess the effects of GI surgery on cardiovascular risk and T2DM-related mortality and morbidity...
Interventional diabetology: the evolution of diabetes care in the XXI centuryAshwin Soni
Section of GI Metabolic Surgery Department of Surgery, Weill Cornell Medical College New York Presbyterian Hospital, 525 East 68th Street, P 714, New York, NY 10065, USA
Curr Atheroscler Rep 14:631-6. 2012..In this manuscript, we discuss how the introduction of interventional diabetology may shape the way we approach diabetes in the 21st century...
Identifying specific surgical tools and methods for laparoscopic colorectal operations in obese patientsTomoki Makino
Section of Colon and Rectal Surgery, New York Presbyterian Hospital and Weill Cornell Medical College, New York, NY 10065, USA
J Gastrointest Surg 16:2304-11. 2012..We believe such an approach will prove beneficial to surgeons performing laparoscopic operations on obese patients...
"Metabolic" surgery for treatment of type 2 diabetes mellitusAaron P Schulman
Department of Medicine, Division of Endocrinology, Weill Cornell Medical College, New York, NY, USA
Endocr Pract 15:624-31. 2009..To discuss the potential contribution of "metabolic" surgery in providing optimal management of patients with type 2 diabetes mellitus (T2DM)...
Gastrointestinal surgery as treatment for type 2 diabetesTracy Ann Moo
Weill Cornell Medical College of Cornell University New York Presbyterian Hospital, New York, New York 10065, USA
Curr Opin Endocrinol Diabetes Obes 15:153-8. 2008..Gastrointestinal bypass surgery is now gaining awareness as a potential effective and long-term treatment...
Insulin sensitivity and secretion changes after gastric bypass in normotolerant and diabetic obese subjectsSerenella Salinari
Department of Computer and System Science, University of Rome Sapienza, Rome, Italy
Ann Surg 257:462-8. 2013..To elucidate the mechanisms of improvement/reversal of type 2 diabetes after Roux-en-Y gastric bypass (RYGB)...
The impact of obesity on perioperative outcomes after laparoscopic colorectal resectionTomoki Makino
Section of Colon and Rectal Surgery, New York Presbyterian Hospital and Weill Cornell Medical College, New York, NY 10065, USA
Ann Surg 255:228-36. 2012..The aim of this review was to evaluate the feasibility and safety of laparoscopic colectomy for colorectal diseases in obese patients compared with nonobese patients...
Surgical treatment of type 2 diabetes: the surgeon perspectiveAlpana P Shukla
Section of GI Metabolic Surgery, New York Presbyterian Hospital and Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA
Endocrine 40:151-61. 2011..The available evidence warrants the inclusion of metabolic surgery in the treatment algorithm of type 2 diabetes...
Metabolic surgery for type 2 diabetesSoo Min Ahn
Department of Surgery, Weill Cornell Medical Center, New York Presbyterian Hospital, New York, New York 10065, USA
Ann N Y Acad Sci 1212:E37-45. 2010..We review the existing knowledge regarding the clinical outcomes and of the mechanisms of GI surgery to treat T2DM...
Gastric inhibitory peptide controls adipose insulin sensitivity via activation of cAMP-response element-binding protein and p110β isoform of phosphatidylinositol 3-kinaseSameer Mohammad
Department of Biochemistry, Weill Medical College of Cornell University, New York, New York 10065, USA
J Biol Chem 286:43062-70. 2011..The insulin-sensitizing activity points to a more central role for GIP in intestinal regulation of peripheral tissue metabolism, an emerging feature of inter-organ communication in the control of metabolism...
Potential of surgery for curing type 2 diabetes mellitusFrancesco Rubino
IRCAD European Institute of Telesurgery, Strasbourg, France
Ann Surg 236:554-9. 2002....
Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old diseaseFrancesco Rubino
IRCAD EITS European Institue of Telesurgery, Louis Pasteur University, Strasbourg, France
Ann Surg 239:1-11. 2004..The aim of this study was to investigate whether duodenal-jejunal exclusion can control diabetes independently on resolution of obesity-related abnormalities...
The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolismFrancesco Rubino
IRCAD-EITS, Strasbourg, France
Ann Surg 240:236-42. 2004..CONCLUSIONS: Roux-en-Y gastric bypass determines considerable hormonal changes before significant BMI changes take place. These results support the hypothesis of an endocrine effect as the possible mechanism of action of RYGB...
Weight loss and plasma ghrelin levelsFrancesco Rubino
N Engl J Med 347:1379-81; author reply 1379-81. 2002
The role of the small bowel in the regulation of circulating ghrelin levels and food intake in the obese Zucker ratFrancesco Rubino
Institut de Recherche Contre les Canceurs de l Appareil Digestif European Institute of Telesurgery, 1 Place de l Hopital, 67091 Strasbourg, France
Endocrinology 146:1745-51. 2005....
The impact of obesity on technical feasibility and postoperative outcomes of laparoscopic left colectomyJoel Leroy
IRCAD/European Institute of Telesurgery, , Strasbourg, France
Ann Surg 241:69-76. 2005..Our study supports the safety of using laparoscopic surgery for colorectal diseases in obese patients...
Late gastric prolapse with pouch necrosis after laparoscopic adjustable gastric bandingSorinel Lunca
IRCAD/EITS, University of Medicine Louis Pasteur, Strasbourg, France
Obes Surg 15:571-5. 2005..Initial referral to a specialized center is necessary for proper care of this complication. Failure of conservative treatment mandates early operative intervention...
Bariatric surgery: effects on glucose homeostasisFrancesco Rubino
IRCAD EITS European Institute of Telesurgery, University Louis Pasteur, Strasbourg, France
Curr Opin Clin Nutr Metab Care 9:497-507. 2006..It focuses on current hypotheses about the mechanism of diabetes control after Roux-en-Y gastric bypass surgery, and discusses the relationship between gastrointestinal anatomy and glucose homeostasis...
The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetesFrancesco Rubino
IRCAD European Institute of Telesurgery, University Louis Pasteur, Strasbourg, France
Ann Surg 244:741-9. 2006..We sought to distinguish between these two mechanisms...
Duodenal-jejunal bypass for the treatment of type 2 diabetes in patients with body mass index of 22-34 kg/m2: a report of 2 casesRicardo V Cohen
Center for Surgical Treatment of Morbid Obesity, , , , Brazil
Surg Obes Relat Dis 3:195-7. 2007
Risk of gastric cancer after Roux-en-Y gastric bypassHarutaka Inoue
Institut de Recherche Contre les Canceurs de l Appareil Digestif European Institute of Telesurgery, 1 Place de l Hopital, 67091 Strasbourg, France
Arch Surg 142:947-53. 2007..To evaluate the risk of gastric cancer after Roux-en-Y gastric bypass (RYGB)...
