G J Randolph

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
    G J Randolph
    Department of Pathology, Cornell University Medical College, 1300 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 95:6924-9. 1998
  2. ncbi request reprint Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking
    G J Randolph
    Department of Pathology, Cornell University Medical College, 1300 York Avenue, Room C 420, New York, NY 10021, USA
    Science 282:480-3. 1998
  3. ncbi request reprint The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes
    D F Robbiani
    Department of Pathology and Immunology Program Weill Medical College and Graduate School of Medical Sciences of Cornell University, New York, NY 10029, USA
    Cell 103:757-68. 2000
  4. ncbi request reprint Migration of leukocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes
    W A Muller
    Department of Pathology, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Leukoc Biol 66:698-704. 1999
  5. ncbi request reprint Role of tissue factor in adhesion of mononuclear phagocytes to and trafficking through endothelium in vitro
    G J Randolph
    Department of Pathology, Cornell University Medical College, New York, NY, USA
    Blood 92:4167-77. 1998
  6. ncbi request reprint Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
    G J Randolph
    Department of Pathology, Weill Medical College of Cornell University, New York, USA
    Immunity 11:753-61. 1999
  7. ncbi request reprint Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators
    G J Randolph
    Institute for Gene Therapy and Molecular Medicine, Mt Sinai School of Medicine, 1425 Madison Avenue, Box 1496, New York, NY 10029, USA
    Semin Immunol 13:267-74. 2001
  8. pmc The fate of monocytes in atherosclerosis
    G J Randolph
    Department of Gene and Cell Medicine, and the Immunology Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Thromb Haemost 7:28-30. 2009

Collaborators

Detail Information

Publications8

  1. pmc A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
    G J Randolph
    Department of Pathology, Cornell University Medical College, 1300 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 95:6924-9. 1998
    ....
  2. ncbi request reprint Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking
    G J Randolph
    Department of Pathology, Cornell University Medical College, 1300 York Avenue, Room C 420, New York, NY 10021, USA
    Science 282:480-3. 1998
    ..Monocytes that remained in the subendothelial matrix became macrophages. Therefore, monocytes have two potential fates associated with distinct patterns of migration...
  3. ncbi request reprint The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes
    D F Robbiani
    Department of Pathology and Immunology Program Weill Medical College and Graduate School of Medical Sciences of Cornell University, New York, NY 10029, USA
    Cell 103:757-68. 2000
    ..Thus, MRP-1 regulates DC migration to lymph nodes, apparently by transporting LTC(4), which in turn promotes chemotaxis to CCL19 and mobilization of DCs from the epidermis...
  4. ncbi request reprint Migration of leukocytes across endothelium and beyond: molecules involved in the transmigration and fate of monocytes
    W A Muller
    Department of Pathology, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Leukoc Biol 66:698-704. 1999
    ..We postulate that a major source of DC in lymph nodes is cells derived from monocytes that enter a tissue via the blood and leave several days later via afferent lymphatic channels...
  5. ncbi request reprint Role of tissue factor in adhesion of mononuclear phagocytes to and trafficking through endothelium in vitro
    G J Randolph
    Department of Pathology, Cornell University Medical College, New York, NY, USA
    Blood 92:4167-77. 1998
    ..This binding was blocked by anti-TF MoAb, suggesting that endothelial cells bear a receptor for TF. These data suggest that mononuclear phagocytes use TF, perhaps as an adhesive protein, to exit sites of inflammation...
  6. ncbi request reprint Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
    G J Randolph
    Department of Pathology, Weill Medical College of Cornell University, New York, USA
    Immunity 11:753-61. 1999
    ..Thus, a substantial minority of inflammatory monocytes carry phagocytosed particles to lymph nodes and differentiate into DCs...
  7. ncbi request reprint Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators
    G J Randolph
    Institute for Gene Therapy and Molecular Medicine, Mt Sinai School of Medicine, 1425 Madison Avenue, Box 1496, New York, NY 10029, USA
    Semin Immunol 13:267-74. 2001
    ..Indeed, MRP1 and the related multidrug resistance protein 1 (MDR1, p-glycoprotein, ABCB1) may control the intracellular and extracellular accumulation of key signaling lipids that regulate dendritic cell migration...
  8. pmc The fate of monocytes in atherosclerosis
    G J Randolph
    Department of Gene and Cell Medicine, and the Immunology Institute, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Thromb Haemost 7:28-30. 2009
    ..All of these points of intervention will be briefly discussed in this article...