Edyta C Pirog
Affiliation: Cornell University
- P16/CDKN2A and Ki-67 enhance the detection of anal intraepithelial neoplasia and condyloma and correlate with human papillomavirus detection by polymerase chain reactionEdyta C Pirog
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10065, USA
Am J Surg Pathol 34:1449-55. 2010..These results indicate that a combination of these markers may aid interpretation of anal mucosal biopsy samples...
- Proliferative activity of benign and neoplastic endocervical epithelium and correlation with HPV DNA detectionEdyta C Pirog
Department of Pathology, Weill Medical College of Cornell University, New York, New York 10021, USA
Int J Gynecol Pathol 21:22-6. 2002..In conclusion, MIB-1 is a useful marker of endocervical neoplasia, although in rare cases an overlap between benign and neoplastic cases may exist...
- Diagnosis of HPV-negative, gastric-type adenocarcinoma of the endocervixEdyta C Pirog
Department of Pathology, Weill Medical College of Cornell University, 525 E 68th Street, ST 1041, New York, NY, 10065, USA
Methods Mol Biol 1249:213-9. 2015..A protocol for HIK1083 immunostaining is described. ..
- Low-grade squamous intraepithelial lesions of the cervix with marked cytological atypia-clinical follow-up and human papillomavirus genotypingKay Park
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Int J Gynecol Pathol 26:457-62. 2007..Marked cytological atypia in LSILs identifies a subset of patients with a high rate of HSIL on follow-up. In such patients, an excisional cone biopsy should be strongly considered...
- Low-grade vulvar and vaginal intraepithelial neoplasia: correlation of histologic features with human papillomavirus DNA detection and MIB-1 immunostainingSanjay Logani
Department of Pathology, Emory University School of Medicine, Atlanta, GA, USA
Mod Pathol 16:735-41. 2003..In contrast, the majority (84%) of VAIN1 cases were associated with high-risk HPVs. In conclusion, MIB-1 staining is sensitive and specific for identifying VIN1/VAIN1, helpful in verifying the diagnosis in equivocal cases...
- p16 and Ki-67 immunostaining in atypical immature squamous metaplasia of the uterine cervix: correlation with human papillomavirus detectionLori Iaconis
Department of Pathology, Beth Israel Hospital, New York, NY, USA
Arch Pathol Lab Med 131:1343-9. 2007..Atypical immature squamous metaplasia (AIM) of the cervix is a loosely defined entity characterized by immature metaplastic cells with mild cytologic atypia...
- Detection of microinvasion in vulvar and cervical intraepithelial neoplasia using double immunostaining for cytokeratin and basement membrane componentsDemaretta Rush
Department of Pathology and Laboratory Medicine, Malcolm Randall VA Medical Center, and University of Florida College of Medicine, Gainesville, USA
Arch Pathol Lab Med 129:747-53. 2005..Presence of obscuring inflammation and tangential tissue sectioning are the most common diagnostic pitfalls...
- Immunoprofile of adenocarcinomas of the endometrium, endocervix, and ovary with mucinous differentiationKay J Park
Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Appl Immunohistochem Mol Morphol 17:8-11. 2009..In gynecologic mucinous tumors with intestinal differentiation, the overlap of staining positivity may be a limiting factor. However, a dominant CK7 staining pattern was observed...
- Prevalence and typing of HPV DNA in atypical squamous cells in pregnant womenDanielle W Lu
Department of Pathology, Huntington Memorial Hospital, 100 West California Boulevard, Pasadena, California 91105, USA
Acta Cytol 47:1008-16. 2003..To determine the prevalence and typing of HPV DNA in pregnant women with a diagnosis of atypical squamous cells (ASC) and to assess whether pregnancy-related changes contribute to the diagnosis of ASC...
- Unusual endocervical adenocarcinomas: an immunohistochemical analysis with molecular detection of human papillomavirusKay J Park
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York Presbyterian Hospital Weill Cornell Medical Center, New York, NY, USA
Am J Surg Pathol 35:633-46. 2011..The goal of our study was to determine the HPV status and immunohistochemical profiles of unusual histologic subtypes of endocervical adenocarcinoma...
- Clinical, pathologic, and molecular features of early-onset colorectal carcinomaRhonda K Yantiss
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10021, USA
Am J Surg Pathol 33:572-82. 2009..Posttranslational regulation of mRNA and subsequent protein expression may be particularly important to the development of colorectal carcinomas in young patients...
- Immunohistochemical differences between mucinous and microglandular adenocarcinomas of the endometrium and benign endocervical epitheliumMarina Chekmareva
Department of Pathology, Robert Wood Johnson University Hospital, New Brunswick, NJ, USA
Int J Gynecol Pathol 27:547-54. 2008..In conclusion, epithelial p16 and stromal CD10/CD34 immunostaining can be useful in distinguishing MUC-AD and MIGL-AD from benign endocervical epithelium in endometrial sampling...
- The Bethesda System 2001 recommendation for reporting of benign appearing endometrial cells in Pap tests of women age 40 years and older leads to unwarranted surveillance when followed without clinical qualifiersDeniz L Aslan
Department of Pathology, New York, Presbyterian Hospital Weill Cornell Medical Center, Papanicolaou Cytology Laboratory Room F766B, 525 E 68th St, New York, NY 10021, USA
Gynecol Oncol 107:86-93. 2007....
- Comparison of human papillomavirus DNA prevalence in atypical squamous cells of undetermined significance subcategories as defined by the original Bethesda 1991 and the new Bethesda 2001 SystemsEdyta C Pirog
Department of Pathology, The Papanicolaou Laboratory, Weill Medical College of Cornell University, New York, NY 10021, USA
Arch Pathol Lab Med 128:527-32. 2004..The new Bethesda System 2001 (TBS 2001) minimized the subclassification of atypical squamous cells of undetermined significance (ASCUS)...
- The diagnosis of endometrial carcinomas with clear cells by gynecologic pathologists: an assessment of interobserver variability and associated morphologic featuresOluwole Fadare
Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA
Am J Surg Pathol 36:1107-18. 2012..Cases that display broad and significant qualitative deviations from the aforementioned profile should prompt the consideration of a diagnosis other than CCC...
- Diagnostic Accuracy of Cervical Low-Grade Squamous Intraepithelial Lesions Is Improved With MIB-1 ImmunostainingEdyta C Pirog
Department of Pathology, Weill Medical College of Cornell University, New York, NY 10021, USA
Am J Surg Pathol 26:70-5. 2002..9) and the specificity (0.8) of HPV testing. In conclusion, MIB-1 is a highly sensitive and specific marker for identifying low-grade squamous intraepithelial lesion and is helpful in verifying the diagnosis of equivocal cases...