Research Topics
Genomes and GenesSpecies | Gillian A PerkinsSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Investigation of the prevalence of neurologic equine herpes virus type 1 (EHV-1) in a 23-year retrospective analysis (1984-2007)Gillian A Perkins
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Microbiol 139:375-8. 2009....
Evaluation of metaphylactic RNA interference to prevent equine herpesvirus type 1 infection in experimental herpesvirus myeloencephalopathy in horsesGillian A Perkins
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 74:248-56. 2013....
Histamine bronchoprovocation does not affect bronchoalveolar lavage fluid cytology, gene expression and protein concentrations of IL-4, IL-8 and IFN-gammaG A Perkins
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States
Vet Immunol Immunopathol 126:230-5. 2008..IL-4 protein was undetectable in BALF either prior to or following HBP. We conclude that HBP can precede BALF collection performed within 2-4h of the former without affecting selected parameters analysed in the BAL cells or BALF...
Detection of equine herpesvirus-1 in nasal swabs of horses by quantitative real-time PCRG A Perkins
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 22:1234-8. 2008..A direct comparison between nasal swab qPCR and traditional virus isolation (VI) requires a method for normalizing the qPCR samples and controlling for PCR inhibitors present in some clinical samples...
Hemothorax in 2 horsesG Perkins
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 13:375-8. 1999..In neither case was pleural blood removed. The hemothorax resolved in both horses without lasting abnormalities. Hemothorax does not require drainage for successful resolution...
Ulcerative dermatitis, thrombocytopenia, and neutropenia in neonatal foalsG A Perkins
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 19:211-6. 2005....
Serum IgM concentrations in normal, fit horses and horses with lymphoma or other medical conditionsG A Perkins
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Vet Intern Med 17:337-42. 2003..Therefore, serum IgM concentrations should not be used as a screening test for equine lymphoma...
A single-nucleotide polymorphism in a herpesvirus DNA polymerase is sufficient to cause lethal neurological diseaseGerlinde R Van De Walle
Department of Microbiology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
J Infect Dis 200:20-5. 2009....
The effect of siRNA treatment on experimental equine herpesvirus type 1 (EHV-1) infection in horsesMargaret M Brosnahan
Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA
Virus Res 147:176-81. 2010....
Effective treatment of respiratory alphaherpesvirus infection using RNA interferenceAmy Fulton
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
PLoS ONE 4:e4118. 2009..CONCLUSIONS/SIGNIFICANCE: siRNA treatment has potential for both prevention and early treatment of EHV-1 infections...
A point mutation in a herpesvirus polymerase determines neuropathogenicityLaura B Goodman
Department of Microbiology and Immunology, Cornell University, Ithaca, New York, United States of America
PLoS Pathog 3:e160. 2007....
Live-attenuated recombinant equine herpesvirus type 1 (EHV-1) induces a neutralizing antibody response against West Nile virus (WNV)Cristina T Rosas
Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA
Virus Res 125:69-78. 2007..From the results, we concluded that the EHV-1 vectored virus is able to express the WNV structural proteins and that vaccination of horses results in the induction of WNV E-protein-specific IgG(T), IgGb, and neutralizing antibodies...
Clinical signs, computed tomographic imaging, and management of chronic otitis media/interna in dairy calvesJérôme Van Biervliet
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
J Vet Intern Med 18:907-10. 2004
Prognostic value of plasma L-lactate concentration measured cow-side with a portable clinical analyzer in Holstein dairy cattle with abomasal disordersMonica D Figueiredo
Department of Clinical Sciences College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA
J Vet Intern Med 20:1463-70. 2006..CONCLUSIONS AND CLINICAL IMPORTANCE: Plasma L-lactate concentration might be a useful predictor of productive outcomes in cows with right-sided abomasal disorders...
Survival of foals with experimentally induced Rhodococcus equi infection given either hyperimmune plasma containing R. equi antibody or normal equine plasmaGillian A Perkins
Cornell University, New York State College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY 14853, USA
Vet Ther 3:334-46. 2002..equi, although the exact constituent responsible for protection is undetermined and requires further investigation...
The effect of adding oral dexamethasone to feed alterations on the airway cell inflammatory gene expression in stabled horses affected with recurrent airway obstructionL Deluca
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
J Vet Intern Med 22:427-35. 2008..Chemokine expression in airway epithelium and bronchoalveolar lavage fluid (BALF) cells of horses with recurrent airway obstruction (RAO) is increased...
Cerebrospinal fluid eosinophilia is a sensitive and specific test for the diagnosis of Parelaphostrongylus tenuis in camelids in the northeastern United StatesToby L Pinn
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
J Vet Diagn Invest 25:54-60. 2013..06; P < 0.0001; 95% CI AUC: 0.76-0.97). Cerebrospinal fluid eosinophil percentage and concentration are sensitive and specific methods for diagnosing P. tenuis antemortem in camelids residing in regions endemic to white-tailed deer...
Diagnosis and treatment of Eimeria macusaniensis in an adult alpaca with signs of colicAmy L Johnson
Department of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, NY 14853, USA
Vet J 179:465-7. 2009..This communication demonstrates the potential pathogenicity of E. macusaniensis in adult alpacas. Coccidian enteropathy should be considered in adult alpacas with gastrointestinal signs including acute abdominal pain and hypoproteinemia...
Plasma adrenocorticotropin (ACTH) concentrations and clinical response in horses treated for equine Cushing's disease with cyproheptadine or pergolideG A Perkins
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853, USA
Equine Vet J 34:679-85. 2002..There were no differences between cyproheptadine and pergolide in terms of improvements in any of the clinical signs...
Clostridial myonecrosis in horses (37 cases 1985-2000)S F Peek
Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA
Equine Vet J 35:86-92. 2003..v. antibiotic therapy and surgical fenestration/debridement is the best approach to cases of clostridial myonecrosis. With rapid diagnosis and therapeutic intervention, horses may have up to an 81% chance of survival...
Cervical vertebral spinal hematomas in 4 horsesJ R Gold
Bend Equine Medical Center, Bend, OR, USA
J Vet Intern Med 22:481-5. 2008
