L G Palmer

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Aldosterone and potassium secretion by the cortical collecting duct
    L G Palmer
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10021, USA
    Kidney Int 57:1324-8. 2000
  2. ncbi request reprint Potassium secretion and the regulation of distal nephron K channels
    L G Palmer
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Physiol 277:F821-5. 1999
  3. pmc Regulation of ROMK by extracellular cations
    H Sackin
    Department of Physiology and Biophysics, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Biophys J 80:683-97. 2001
  4. pmc Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels
    H Sackin
    Department of Physiology and Biophysics, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Biophys J 86:2145-55. 2004
  5. pmc Regulation of Na+ channels by luminal Na+ in rat cortical collecting tubule
    L G Palmer
    Department of Physiology and Biophysics, Cornell University Medical College, New York, NY 10021, USA
    J Physiol 509:151-62. 1998
  6. ncbi request reprint Gating properties of inward-rectifier potassium channels: effects of permeant ions
    H Choe
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    J Membr Biol 184:81-9. 2001
  7. ncbi request reprint Intracellular pH as a regulator of Na + transport
    L G Palmer
    Dept. of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Ave, New York, NY 10021, USA
    J Membr Biol 184:305-11. 2001
  8. ncbi request reprint Feedback regulation of Na channels in rat CCT. IV. Mediation by activation of protein kinase C
    G Frindt
    Department of Physiology and Biophysics, Cornell University Medical College, New York, New York 10021, USA
    Am J Physiol 270:F371-6. 1996
  9. ncbi request reprint Activation of epithelial Na channels during short-term Na deprivation
    G Frindt
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Physiol Renal Physiol 280:F112-8. 2001
  10. pmc Permeant cations and blockers modulate pH gating of ROMK channels
    H Sackin
    Department of Physiology and Biophysics, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Biophys J 84:910-21. 2003

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Aldosterone and potassium secretion by the cortical collecting duct
    L G Palmer
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10021, USA
    Kidney Int 57:1324-8. 2000
    ..However, the correlation between changes in mineralocorticoid levels and rates of K secretion is not perfect, suggesting that other factors may be involved...
  2. ncbi request reprint Potassium secretion and the regulation of distal nephron K channels
    L G Palmer
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Physiol 277:F821-5. 1999
    ..Giebisch. Am. J. Physiol. 274 (Renal Physiol. 43): F817-F833, 1998]. Here I will focus on a few prominent unsolved problems...
  3. pmc Regulation of ROMK by extracellular cations
    H Sackin
    Department of Physiology and Biophysics, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Biophys J 80:683-97. 2001
    ..Mutation of a pH-sensing site (ROMK2-K61) prevents transitions from activated to inactivated modes. This is consistent with a direct effect of external K or Cs on the gating of ROMK by internal pH...
  4. pmc Potassium-dependent slow inactivation of Kir1.1 (ROMK) channels
    H Sackin
    Department of Physiology and Biophysics, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Biophys J 86:2145-55. 2004
    ....
  5. pmc Regulation of Na+ channels by luminal Na+ in rat cortical collecting tubule
    L G Palmer
    Department of Physiology and Biophysics, Cornell University Medical College, New York, NY 10021, USA
    J Physiol 509:151-62. 1998
    ..6. The results are consistent with the concept of self-inhibition of Na+ channels by luminal Na+. Activation of the channels by lowering [Na+]o is not additive with that achieved by hyperpolarization...
  6. ncbi request reprint Gating properties of inward-rectifier potassium channels: effects of permeant ions
    H Choe
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    J Membr Biol 184:81-9. 2001
    ..The patterns of voltage-dependence of closed-state lifetimes, which are specific for different ions, can be explained by variations in the rate at which the bound ions leave the pore toward the inside or the outside of the cell...
  7. ncbi request reprint Intracellular pH as a regulator of Na + transport
    L G Palmer
    Dept. of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Ave, New York, NY 10021, USA
    J Membr Biol 184:305-11. 2001
    ..This suggests the possibility that cell pH may serve as an important regulator of transport.One possible role is as a second messenger for rapid effects of the adrenal mineralocorticoid aldosterone...
  8. ncbi request reprint Feedback regulation of Na channels in rat CCT. IV. Mediation by activation of protein kinase C
    G Frindt
    Department of Physiology and Biophysics, Cornell University Medical College, New York, New York 10021, USA
    Am J Physiol 270:F371-6. 1996
    ..The results support the view that the downregulation caused by ouabain involves the Ca(2+)-dependent phosphorylation of the channel itself or of proteins regulating the channel...
  9. ncbi request reprint Activation of epithelial Na channels during short-term Na deprivation
    G Frindt
    Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Physiol Renal Physiol 280:F112-8. 2001
    ..Calculations of the rate of Na transport mediated by the Na channels indicated that activation of the channels during short-term Na deprivation could account in large part for the increased Na reabsorption under these conditions...
  10. pmc Permeant cations and blockers modulate pH gating of ROMK channels
    H Sackin
    Department of Physiology and Biophysics, The Chicago Medical School, North Chicago, Illinois 60064, USA
    Biophys J 84:910-21. 2003
    ..In this context, external K, Cs, and Tertiapin-Q activate ROMK by destabilizing the low-K (collapsed) configuration of the selectivity filter...
  11. pmc Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells
    S A Rajasekaran
    Department of Physiology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Mol Biol Cell 12:3717-32. 2001
    ..These results thus demonstrate that the Na,K-ATPase activity plays an important role in regulating both the structure and function of polarized epithelial cells...
  12. ncbi request reprint Primary structure and functional properties of an epithelial K channel
    H Zhou
    Department of Physiology and Biophysics, Cornell University Medical College, New York, New York 10021
    Am J Physiol 266:C809-24. 1994
    ..This channel may be involved in maintaining the membrane potential of renal cells and/or mediating renal K secretion...