TERESA MILNER

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Selective changes in hippocampal neuropeptide Y neurons following removal of the cholinergic septal inputs
    T A Milner
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
    J Comp Neurol 386:46-59. 1997
  2. ncbi request reprint Receptor targeting in medullary nuclei mediating baroreceptor reflexes
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, New York, USA
    Cell Mol Neurobiol 23:751-60. 2003
  3. ncbi request reprint Cellular and subcellular localization of androgen receptor immunoreactivity relative to C1 adrenergic neurons in the rostral ventrolateral medulla of male and female rats
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    Synapse 61:268-78. 2007
  4. ncbi request reprint Ultrastructural localization of estrogen receptor beta immunoreactivity in the rat hippocampal formation
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York 10021, USA
    J Comp Neurol 491:81-95. 2005
  5. ncbi request reprint C1 adrenergic neurons are contacted by presynaptic profiles containing DELTA-opioid receptor immunoreactivity
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Neuroscience 110:691-701. 2002
  6. ncbi request reprint Cellular relations between mu-opioid receptive, GABAergic and reticulospinal neurons in the rostral ventrolateral medulla
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Brain Res 917:1-14. 2001
  7. ncbi request reprint Ultrastructural evidence for presynaptic mu opioid receptor modulation of synaptic plasticity in NMDA-receptor-containing dendrites in the dentate gyrus
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Brain Res Bull 54:131-40. 2001
  8. ncbi request reprint Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Comp Neurol 429:355-71. 2001
  9. ncbi request reprint Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes
    T A Milner
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
    J Comp Neurol 395:310-27. 1998
  10. ncbi request reprint Parvalbumin immunoreactive neurons in the rat septal complex have substantial glial coverage and receive few direct contacts from catecholaminergic terminals
    T A Milner
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
    J Neurosci Res 52:723-35. 1998

Research Grants

  1. STRESS-OPIOID INTERACTION IN HIPPOCAMPUS
    TERESA MILNER; Fiscal Year: 2009
  2. CORE-- Neuroanatomy-Imaging
    TERESA MILNER; Fiscal Year: 2007
  3. Estrogen-Opioid interactions in hippocampus
    TERESA MILNER; Fiscal Year: 2007
  4. Developmental Affects of Ritalin on Brain
    TERESA MILNER; Fiscal Year: 2004
  5. ULTRASTRUCTURAL INTERACTIONS OF OPIOIDS IN HIPPOCAMPUS
    TERESA MILNER; Fiscal Year: 2002
  6. STRESS-OPIOID INTERACTION IN HIPPOCAMPUS
    Teresa A Milner; Fiscal Year: 2010

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Selective changes in hippocampal neuropeptide Y neurons following removal of the cholinergic septal inputs
    T A Milner
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
    J Comp Neurol 386:46-59. 1997
    ..The changes in NPY immunoreactivity seem to occur in the portion of interneurons that probably does not contain either SOM or GABA immunoreactivity...
  2. ncbi request reprint Receptor targeting in medullary nuclei mediating baroreceptor reflexes
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, New York, USA
    Cell Mol Neurobiol 23:751-60. 2003
    ....
  3. ncbi request reprint Cellular and subcellular localization of androgen receptor immunoreactivity relative to C1 adrenergic neurons in the rostral ventrolateral medulla of male and female rats
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    Synapse 61:268-78. 2007
    ....
  4. ncbi request reprint Ultrastructural localization of estrogen receptor beta immunoreactivity in the rat hippocampal formation
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York 10021, USA
    J Comp Neurol 491:81-95. 2005
    ..These results suggest that ERbeta may serve primarily as a nongenomic transducer of estrogen actions in the hippocampal formation...
  5. ncbi request reprint C1 adrenergic neurons are contacted by presynaptic profiles containing DELTA-opioid receptor immunoreactivity
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Neuroscience 110:691-701. 2002
    ....
  6. ncbi request reprint Cellular relations between mu-opioid receptive, GABAergic and reticulospinal neurons in the rostral ventrolateral medulla
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Brain Res 917:1-14. 2001
    ....
  7. ncbi request reprint Ultrastructural evidence for presynaptic mu opioid receptor modulation of synaptic plasticity in NMDA-receptor-containing dendrites in the dentate gyrus
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Brain Res Bull 54:131-40. 2001
    ....
  8. ncbi request reprint Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Comp Neurol 429:355-71. 2001
    ..Collectively, these results suggest that ERalpha may serve as both a genomic and nongenomic transducer of estrogen action in the HF...
  9. ncbi request reprint Hippocampal alpha2a-adrenergic receptors are located predominantly presynaptically but are also found postsynaptically and in selective astrocytes
    T A Milner
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
    J Comp Neurol 395:310-27. 1998
    ..These results suggest several sites for NE to exert its effects on hippocampal alpha2A-ARs...
  10. ncbi request reprint Parvalbumin immunoreactive neurons in the rat septal complex have substantial glial coverage and receive few direct contacts from catecholaminergic terminals
    T A Milner
    Department of Neurology and Neuroscience, Cornell University Medical College, New York, New York 10021, USA
    J Neurosci Res 52:723-35. 1998
    ..These findings further support the functional diversity of subpopulations of septohippocampal neurons...
  11. ncbi request reprint Alpha2A-adrenergic receptors are primarily presynaptic heteroreceptors in the C1 area of the rat rostral ventrolateral medulla
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Cornell University Medical College, 411 East 69th Street, New York, NY 10021, USA
    Brain Res 821:200-11. 1999
    ..These receptors may be activated by catecholamines released either from the dendrites of C1 neurons or from the terminals of other catecholaminergic neurons via volume transmission...
  12. ncbi request reprint Septal cholinergic deafferentation of the dentate gyrus results in a loss of a subset of neuropeptide Y somata and an increase in synaptic area on remaining neuropeptide Y dendrites
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Brain Res 831:322-36. 1999
    ....
  13. ncbi request reprint beta-adrenergic receptors primarily are located on the dendrites of granule cells and interneurons but also are found on astrocytes and a few presynaptic profiles in the rat dentate gyrus
    T A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    Synapse 36:178-93. 2000
    ....
  14. pmc Nuclear and extranuclear estrogen binding sites in the rat forebrain and autonomic medullary areas
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neurosacience, Weill Cornell Medical College, 411 East 69th Street, New York, NY 10021, USA
    Endocrinology 149:3306-12. 2008
    ..The association of (125)I-estradiol binding with pre- and postsynaptic profiles supports a functional role for nonnuclear ERs in brain...
  15. ncbi request reprint Redistribution of mu-opioid receptors in C1 adrenergic neurons following chronic administration of morphine
    Carrie T Drake
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Exp Neurol 196:365-72. 2005
    ....
  16. ncbi request reprint Sex differences in hippocampal estradiol-induced N-methyl-D-aspartic acid binding and ultrastructural localization of estrogen receptor-alpha
    Russell D Romeo
    Laboratory of Neuroendocrinology, The Rockefeller University, Box 165, New York, NY 10021, USA
    Neuroendocrinology 81:391-9. 2005
    ....
  17. ncbi request reprint Evidence that estrogen directly and indirectly modulates C1 adrenergic bulbospinal neurons in the rostral ventrolateral medulla
    Gang Wang
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY 10021, USA
    Brain Res 1094:163-78. 2006
    ..These findings provide a structural and functional basis for the effects of estrogens on blood pressure control and suggest a mechanism for the modulation of cardiovascular function by estrogen in women...
  18. ncbi request reprint Mu opioid receptors are extensively co-localized with parvalbumin, but not somatostatin, in the dentate gyrus
    Carrie T Drake
    Department of Neurology and Neuroscience, Division of Neurobiology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Neurosci Lett 403:176-80. 2006
    ..This suggests that MORs are most frequently on interneurons specialized to inhibit granule cell output, and are on a limited number of interneurons that inhibit granule cell distal dendrites...
  19. ncbi request reprint BDNF-mediated neurotransmission relies upon a myosin VI motor complex
    Hiroko Yano
    Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, Departments of Cell Biology, Physiology and Neuroscience, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA
    Nat Neurosci 9:1009-18. 2006
    ..Together, these results define an important role for the Myo6-GIPC1 motor complex in presynaptic function and in BDNF-TrkB-mediated synaptic plasticity...
  20. pmc Ultrastructural localization of extranuclear progestin receptors in the rat hippocampal formation
    Elizabeth M Waters
    Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, New York 10065, USA
    J Comp Neurol 511:34-46. 2008
    ....
  21. pmc Angiotensin II-induced hypertension differentially affects estrogen and progestin receptors in central autonomic regulatory areas of female rats
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 411 East 69th Street, New York, NY 10021, USA
    Exp Neurol 212:393-406. 2008
    ..Considering that ERalpha counteracts the central and peripheral effects of AngII, these receptor changes may underlie adaptive responses that protect females from the deleterious effects of hypertension...
  22. ncbi request reprint Ultrastructural evidence for pre- and postsynaptic localization of Cav1.2 L-type Ca2+ channels in the rat hippocampus
    Alyssa L Tippens
    Department of Pharmacology, Emory University, Atlanta, Georgia 30322, USA
    J Comp Neurol 506:569-83. 2008
    ..These findings provide the first detailed ultrastructural analysis of Ca(v)1.2 localization in the brain and support functionally diverse roles of these channels in the hippocampal formation...
  23. pmc Uncovering the mechanisms of estrogen effects on hippocampal function
    Joanna L Spencer
    Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, 1300 York Avenue, New York, NY 10065, USA
    Front Neuroendocrinol 29:219-37. 2008
    ..Finally, estrogen may signal through both nuclear and extranuclear hippocampal estrogen receptors to achieve its downstream effects...
  24. pmc Ultrastructural localization of extranuclear progestin receptors relative to C1 neurons in the rostral ventrolateral medulla
    Teresa A Milner
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 411 East 69th Street, New York, NY 10021, United States
    Neurosci Lett 431:167-72. 2008
    ..Moreover, they suggest that PR activation may contribute to progestin's effects on arterial blood pressure during pregnancy as well as to sex differences in central cardiovascular regulation...
  25. doi request reprint Steroid hormone receptor expression and function in microglia
    Amanda Sierra
    Laboratory of Neuroendocrinology, Rockefeller University, New York, New York 10021, USA
    Glia 56:659-74. 2008
    ....
  26. ncbi request reprint Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
    Newton H Woo
    Section on Neural Development and Plasticity, LCSN, NICHD, Porter Neuroscience Research Center, 35 Lincoln Drive, Bethesda, Maryland 20892 3714, USA
    Nat Neurosci 8:1069-77. 2005
    ....
  27. pmc Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology
    Reisuke H Takahashi
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Pathol 161:1869-79. 2002
    ..This accumulation was associated with abnormal synaptic morphology, before beta-amyloid plaque pathology, suggesting that intracellular accumulation of beta-amyloid plays a crucial role in Alzheimer's disease...
  28. ncbi request reprint Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus
    Gerardo G Piroli
    Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, The Rockefeller University, New York, NY 10021, USA
    J Comp Neurol 452:103-14. 2002
    ....
  29. ncbi request reprint Mu opioid receptors are in discrete hippocampal interneuron subpopulations
    Carrie T Drake
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    Hippocampus 12:119-36. 2002
    ....
  30. ncbi request reprint Subcellular relationships between cholinergic terminals and estrogen receptor-alpha in the dorsal hippocampus
    Laura A Towart
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Comp Neurol 463:390-401. 2003
    ....
  31. ncbi request reprint Dendritic ribosomes suggest local protein synthesis during estrous synaptogenesis
    J Brian McCarthy
    Department of Pharmacology, Uniformed Services University of the Health Sciences, US Department of Defense, Bethesda, MD 20814, USA
    Neuroreport 14:1357-60. 2003
    ..These findings are consistent with a role for estrogen in regulating the local synthesis of integral membrane proteins, e.g. receptors, in dendrites for newly developing synapses across the estrous cycle...
  32. ncbi request reprint Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain
    Reisuke H Takahashi
    Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Neurosci 24:3592-9. 2004
    ..These Abeta42 oligomer accumulations are associated with pathological alterations within processes and synaptic compartments in Tg2576 mouse and human AD brains...
  33. ncbi request reprint Estrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats
    Michelle M Adams
    Kastor Neurobiology of Aging Laboratories, Fishberg Research Center for Neurobiology, and Henry L Schwartz Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    J Neurosci 22:3608-14. 2002
    ..Such a role for spinous ER-alpha has important implications for age-related attenuation of estrogen-induced hippocampal plasticity...
  34. ncbi request reprint Evidence for endogenous agmatine in hypothalamo-neurohypophysial tract and its modulation on vasopressin release and Ca2+ channels
    Gang Wang
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Brain Res 932:25-36. 2002
    ....
  35. ncbi request reprint Estrogen levels regulate the subcellular distribution of phosphorylated Akt in hippocampal CA1 dendrites
    Vladimir Znamensky
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA
    J Neurosci 23:2340-7. 2003
    ..These findings suggest that estrogens may regulate spine formation in CA1 pyramidal neurons via Akt-mediated signaling events...
  36. ncbi request reprint Opioid systems in the dentate gyrus
    Carrie T Drake
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Cornell Medical College, 411 East 69th Street, New York, NY 10021, USA
    Prog Brain Res 163:245-63. 2007
    ..Recent evidence indicates that opiates and opioids also modulate other processes in the hippocampal formation, including adult neurogenesis, the actions of gonadal hormones, and development of neonatal transmitter systems...
  37. pmc Hippocampal formation: shedding light on the influence of sex and stress on the brain
    Bruce S McEwen
    Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology, Rockefeller University, 1300 York Avenue, New York, NY 10021, USA
    Brain Res Rev 55:343-55. 2007
    ..This new view is consistent with the predictions of Cajal in his book "The Structure of Ammon's horn", 1892...
  38. ncbi request reprint Attenuation of activity-induced increases in cerebellar blood flow by lesion of the inferior olive
    Yi Zhang
    Division of Neurobiology, Department of Neurobiology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Am J Physiol Heart Circ Physiol 285:H1177-82. 2003
    ..Thus the hemodynamic response evoked by functional activation of the cerebellar cortex reflects, in large part, CF activity...
  39. ncbi request reprint Ultrastructural evidence for mu-opioid modulation of cholinergic pathways in rat dentate gyrus
    Theodore J Kaplan
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, 411 East 69th Street, New York, NY 10021, USA
    Brain Res 1019:28-38. 2004
    ..The results of this study provide ultrastructural evidence for direct and indirect modulation of cholinergic systems by mu-opioids in the hippocampal formation...
  40. ncbi request reprint Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals
    Ken Kazama
    Division of Neurobiology, Department of Neurology and Neuroscience, Weill Medical College of Cornell University, New York, NY, USA
    Circ Res 95:1019-26. 2004
    ..The data provide the mechanistic basis for the cerebrovascular dysregulation induced by Ang II and suggest novel therapeutic strategies to counteract the effects of hypertension on the brain...
  41. ncbi request reprint Extranuclear estrogen receptor beta immunoreactivity is on doublecortin-containing cells in the adult and neonatal rat dentate gyrus
    Scott P Herrick
    Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY 10021, USA
    Brain Res 1121:46-58. 2006
    ..These findings are consistent with data showing that estrogens can exert non-genomic effects directly and indirectly on newly generated cells in neonatal and adult rat dentate gyrus...

Research Grants19

  1. STRESS-OPIOID INTERACTION IN HIPPOCAMPUS
    TERESA MILNER; Fiscal Year: 2009
    ..These studies will improve our understanding of sex differences in the nature and etiology of drug abuse and have implications for tailoring treatment interventions to maximize positive outcomes for females and males. ..
  2. CORE-- Neuroanatomy-Imaging
    TERESA MILNER; Fiscal Year: 2007
    ..Major changes are indicated by a line in the left margin. Overall, the Budget has been reduced. A detailed account of the budgetary changes has been included in the Budget Justification. ..
  3. Estrogen-Opioid interactions in hippocampus
    TERESA MILNER; Fiscal Year: 2007
    ..The results will elucidate potential mechanisms and sites where ovarian steroids, by affecting HF opioid systems, may influence hippocampal-dependent learning relevant to drug abuse. ..
  4. Developmental Affects of Ritalin on Brain
    TERESA MILNER; Fiscal Year: 2004
    ..Determining how therapeutic dosage regimens effect these transmitter systems is critical in understanding the safety of long-term therapeutic doses of MPH administered to children and adolescents with ADHD and other related disorders. ..
  5. ULTRASTRUCTURAL INTERACTIONS OF OPIOIDS IN HIPPOCAMPUS
    TERESA MILNER; Fiscal Year: 2002
    ..These studies will provide insight on the contribution of hippocampal opioid neurons to mnemonic processes and the pathologies associated with disorders such as seizures in humans. ..
  6. STRESS-OPIOID INTERACTION IN HIPPOCAMPUS
    Teresa A Milner; Fiscal Year: 2010
    ..These studies will improve our understanding of sex differences in the nature and etiology of drug abuse and have implications for tailoring treatment interventions to maximize positive outcomes for females and males. ..