Christopher E Mason

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. doi The pivotal regulatory landscape of RNA modifications
    Sheng Li
    Department of Physiology and Biophysics and HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065 Email
    Annu Rev Genomics Hum Genet 15:127-50. 2014
  2. pmc Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia
    Altuna Akalin
    Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, United States of America
    PLoS Genet 8:e1002781. 2012
  3. doi Characterizing multi-omic data in systems biology
    Christopher E Mason
    Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA
    Adv Exp Med Biol 799:15-38. 2014
  4. pmc Faster sequencers, larger datasets, new challenges
    Christopher E Mason
    Weill Cornell Medical College, Institute for Computational Biomedicine, Department of Physiology and Biophysics, New York, NY 10021, USA
    Genome Biol 13:314. 2012
  5. pmc Induction of sarcomas by mutant IDH2
    Chao Lu
    Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Genes Dev 27:1986-98. 2013
  6. pmc An optimized algorithm for detecting and annotating regional differential methylation
    Sheng Li
    Department of Physiology and Biophysics, Weill Cornell Medical College, 1305 York Ave, New York, NY 10065, USA
    BMC Bioinformatics 14:S10. 2013
  7. pmc Detecting and correcting systematic variation in large-scale RNA sequencing data
    Sheng Li
    1 Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA 2 The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA 3
    Nat Biotechnol 32:888-95. 2014
  8. pmc Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
    Julia A Meyer
    New York University Cancer Institute, New York University Langone Medical Center, New York, New York, USA
    Nat Genet 45:290-4. 2013
  9. pmc The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics
    Lenore Pipes
    Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065, USA
    Nucleic Acids Res 41:D906-14. 2013
  10. pmc Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons
    Kate D Meyer
    Department of Pharmacology, Weill Medical College, Cornell University, New York, NY 10065, USA
    Cell 149:1635-46. 2012

Collaborators

Detail Information

Publications10

  1. doi The pivotal regulatory landscape of RNA modifications
    Sheng Li
    Department of Physiology and Biophysics and HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10065 Email
    Annu Rev Genomics Hum Genet 15:127-50. 2014
    ....
  2. pmc Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia
    Altuna Akalin
    Department of Physiology and Biophysics and the HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, United States of America
    PLoS Genet 8:e1002781. 2012
    ..Therefore, aberrant DNA methylation patterns in AML do not occur in a stereotypical manner but rather are highly specific and associated with specific driving genetic lesions...
  3. doi Characterizing multi-omic data in systems biology
    Christopher E Mason
    Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA
    Adv Exp Med Biol 799:15-38. 2014
    ..Here, we describe novel approaches in the genesis and processing of such data, models to integrate these data, and the increasing ubiquity of self-reporting and self-measured genomics and health data. ..
  4. pmc Faster sequencers, larger datasets, new challenges
    Christopher E Mason
    Weill Cornell Medical College, Institute for Computational Biomedicine, Department of Physiology and Biophysics, New York, NY 10021, USA
    Genome Biol 13:314. 2012
    ..A report on the Advances in Genome Biology and Technology (AGBT) meeting, Marco Island, Florida, USA, 15-18 February 2012...
  5. pmc Induction of sarcomas by mutant IDH2
    Chao Lu
    Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
    Genes Dev 27:1986-98. 2013
    ..The oncogenic potential of mutant IDH2 correlated with the ability to produce 2-hydroxyglutarate. Together, these data demonstrate that neomorphic IDH2 mutations can be oncogenic in mesenchymal cells. ..
  6. pmc An optimized algorithm for detecting and annotating regional differential methylation
    Sheng Li
    Department of Physiology and Biophysics, Weill Cornell Medical College, 1305 York Ave, New York, NY 10065, USA
    BMC Bioinformatics 14:S10. 2013
    ....
  7. pmc Detecting and correcting systematic variation in large-scale RNA sequencing data
    Sheng Li
    1 Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA 2 The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA 3
    Nat Biotechnol 32:888-95. 2014
    ..Normalization methods that combine data from genes across sites are strongly recommended to identify and remove site-specific effects and can substantially improve RNA-seq studies. ..
  8. pmc Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
    Julia A Meyer
    New York University Cancer Institute, New York University Langone Medical Center, New York, New York, USA
    Nat Genet 45:290-4. 2013
    ..Clinically, all individuals who harbored NT5C2 mutations relapsed early, within 36 months of initial diagnosis (P = 0.03). These results suggest that mutations in NT5C2 are associated with the outgrowth of drug-resistant clones in ALL...
  9. pmc The non-human primate reference transcriptome resource (NHPRTR) for comparative functional genomics
    Lenore Pipes
    Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY 10065, USA
    Nucleic Acids Res 41:D906-14. 2013
    ....
  10. pmc Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons
    Kate D Meyer
    Department of Pharmacology, Weill Medical College, Cornell University, New York, NY 10065, USA
    Cell 149:1635-46. 2012
    ..These findings provide a resource for identifying transcripts that are substrates for adenosine methylation and reveal insights into the epigenetic regulation of the mammalian transcriptome...