Research Topics
| Cynthia MagroSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Cytomegalovirus-associated pulmonary septal capillary injury sine inclusion body change: a distinctive cause of occult or macroscopic pulmonary hemorrhage in the immunocompetent hostCynthia Magro
Department of Pathology, Ohio State University, Columbus, Ohio 43210, USA
Appl Immunohistochem Mol Morphol 13:268-72. 2005....- Unusual histologic and clinical variants of melanoma: implications for therapyA Neil Crowson
Regional Medical Laboratories, St John Medical Center, 1923 S Utica Avenue, Tulsa, OK 74104, USA
Curr Oncol Rep 9:403-10. 2007..As identification of some of these melanoma subtypes has specific implications for the therapeutic approach, and as some may mimic other forms of epithelial or mesenchymal neoplasia, their recognition is key to patient management... - Terbinafine-induced dermatomyositis: a case report and literature review of drug-induced dermatomyositisCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
J Cutan Pathol 35:74-81. 2008..The second may be because of the effects of the drug on the promotion of an interferon-rich T-helper-1-dominant cytokine milieu... 
Indolent primary cutaneous γ/δ T-cell lymphoma localized to the subcutaneous panniculus and its association with atypical lymphocytic lobular panniculitisCynthia M Magro
Department of Pathology and Laboratory Medicine, Room F 309, 1300 York Ave, Weill Medical College of Cornell University, New York, NY, USA
Am J Clin Pathol 138:50-6. 2012..Therefore, it is important to recognize that not all patients with γ/δ T-cell lymphomas have a poor prognosis...- The superficial atypical Spitz tumor and malignant melanoma of superficial spreading type arising in association with the superficial atypical Spitz tumor: A distinct form of dysplastic Spitzoid nevomelanocytic proliferationCynthia M Magro
Division of Dermatopathology, Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 300 York Ave, F 309, New York, NY 10021, USA
J Am Acad Dermatol 60:814-23. 2009..In conclusion, there exists a distinct subset of Spitz tumors that we designate as the superficial atypical Spitz tumor in which there is inherent dysplasia including lesions that evolve into melanoma of superficial spreading type... - Clonality in the setting of Sweet's syndrome and pyoderma gangrenosum is not limited to underlying myeloproliferative diseaseCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
J Cutan Pathol 34:526-34. 2007..The neutrophilic dermatoses encompass, among others, Sweet's syndrome (SS) and pyoderma gangrenosum (PG), which are associated with underlying systemic diseases including myeloid dyscrasias... - Post-transplant EBV-negative anaplastic large-cell lymphoma with dual rearrangement: a propos of two cases and review of the literatureCynthia M Magro
Department of Pathology, Weill Medical College Cornell University, New York, NY 10021, USA
J Cutan Pathol 34:1-8. 2007..The vast majority of these lesions represent monomorphic B-cell lymphoproliferative disease. Rarely, however, T-cell malignancies may emerge, the commonest being anaplastic large-cell lymphoma (ALCL)... - Cutaneous lesions of dermatomyositis with supervening fibrosisCynthia M Magro
Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY 10021, USA
J Cutan Pathol 35:31-9. 2008..The primary organs affected by DM are the skin and muscle. A significant albeit rare complication is pulmonary fibrosis, which our recent study postulated to be attributable to an autoimmune endothelialitis... - Cutaneous lymphocyte antigen expression in benign and neoplastic cutaneous B- and T-cell lymphoid infiltratesCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
J Cutan Pathol 35:1040-9. 2008..It has been postulated to be an important factor in homing of lymphocytes to the skin because of its function as a ligand for E-selectin expressed on cutaneous endothelial cells... - Atypical lymphocytic lobular panniculitis: a clonal subcutaneous T-cell dyscrasiaCynthia M Magro
Department of Dermatopathology, Weill Medical College of Cornell University, New York, NY, USA
J Cutan Pathol 35:947-54. 2008..Atypical lymphocytic lobular panniculitis (ALLP) is a recently described entity characterized by waxing and waning plaques. A morphologic and biologic continuum with subcutaneous panniculitis-like T-cell lymphoma has been suggested... - Acute infectious id panniculitis/panniculitic bacterid: a distinctive form of neutrophilic lobular panniculitisCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA
J Cutan Pathol 35:941-6. 2008..Panniculitis may represent a sign of systemic disease and/or a modified immune response to hematogenously disseminated antigen... - The use of C3d and C4d immunohistochemistry on formalin-fixed tissue as a diagnostic adjunct in the assessment of inflammatory skin diseaseCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10065, USA
J Am Acad Dermatol 59:822-33. 2008.... - Fulminant and accelerated presentation of dermatomyositis in two previously healthy young adult males: a potential role for endotheliotropic viral infectionCynthia M Magro
Dermatopathology Division, Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10065, USA
J Cutan Pathol 36:853-8. 2009..At times, the clinical manifestations in DM can be fulminant with acute renal failure because of rhabdomyolysis, respiratory failure and gastrointestinal infarcts... - Early-onset lichenoid graft-vs.-host disease: a unique variant of acute graft-vs.-host disease occurring in peripheral blood stem cell transplant recipientsCynthia M Magro
Weill Medical College of Cornell University, New York, New York 10065, USA
J Cutan Pathol 37:549-58. 2010..host disease (GvHD), developing months to years after transplant; the two commonest manifestations are lichenoid GvHD and scleroderma. The purpose of this study was to characterize early-onset lichenoid GvHD... - The phenotypic profile of dermatomyositis and lupus erythematosus: a comparative analysisCynthia M Magro
Department of Pathology, New York Presbyterian Hospital Weill Cornell Medical Center, New York, NY 10044, USA
J Cutan Pathol 37:659-71. 2010.... - The dermal-based borderline melanocytic tumor: a categorical approachCynthia M Magro
Department of Pathology, Weill Medical College of Cornell University, 1300 York Ave, F 309, New York, NY 10021, USA
J Am Acad Dermatol 62:469-79. 2010..The criteria that define the BMT are not well defined nor is the concept widely recognized... - Cutaneous CD4+ CD56+ hematologic malignanciesCynthia M Magro
Department of Pathology, Weill Medical College of Cornell University, New York, New York, USA
J Am Acad Dermatol 63:292-308. 2010..Hematologic malignancies expressing CD4 and CD56 are most commonly associated with the recently described CD4(+) CD56(+) hematodermic neoplasm... 
Angiocentric lesions of the head and neckCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 1300 York Ave F 309, New York, NY 10065, USA
Head Neck Pathol 2:116-30. 2008..The two main neoplastic conditions exhibiting angiocentricity are in the context of lymphomatoid granulomatosis and NK/T cell lymphoma; hence these two particular hematologic dyscrasias will be discussed in some detail in this review...- The expression of CD23 and CD40 in primary cutaneous B-cell lymphomasCynthia Magro
Department of Pathology, Weill Medical College of Medicine, NY 10021, USA
J Cutan Pathol 34:461-6. 2007..Positive CD23 expression amidst neoplastic cells in primary cutaneous B-cell lymphoma is not a reported phenomenon... - Drug-associated reversible granulomatous T cell dyscrasia: a distinct subset of the interstitial granulomatous drug reactionCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY 10065, USA
J Cutan Pathol 37:96-111. 2010..Although such an infiltrate could represent a lymphoma, this constellation of findings can also be seen in drug-associated pseudolymphoma... - Cytomegalovirus-associated cutaneous vasculopathy and scleroderma sans inclusion body changeCynthia M Magro
Department of Pathology, Weill College of Medicine, Cornell University, New York, NY 10021, USA
Hum Pathol 38:42-9. 2007..The role of tumor necrosis factor alpha blockers in scleroderma cases temporally associated with CMV infection requires further evaluation... - Automated kappa and lambda light chain mRNA expression for the assessment of B-cell clonality in cutaneous B-cell infiltrates: its utility and diagnostic applicationCynthia Magro
Department of Pathology, Division of Hematology-Oncology, Ohio State University School of Medicine and Public Health, Columbus, OH, USA
J Cutan Pathol 30:504-11. 2003..CONCLUSION: The Ventana kappa/lambda assay is a reliable, quick, and inexpensive way to determine B-cell clonality in cutaneous lymphoid infiltrates in paraffin-embedded formalin-fixed tissue... - The histologic spectrum of epidermodysplasia verruciformis in transplant and AIDS patientsCarl Morrison
Department of Pathology, Ohio State University Medical Center, Columbus, 43210, USA
J Cutan Pathol 29:480-9. 2002.... - Histologic distribution of fatal rotaviral pneumonitis: an immunohistochemical and RT in situ PCR analysisGerard J Nuovo
Department of Pathology, Ohio State University Medical Center, Columbus 43210, USA
Diagn Mol Pathol 11:140-5. 2002..It is concluded that rotaviral infection can lead to fatal pneumonitis and that the mechanism of this complication is centered on a diffuse septal endothelialitis with concomitant tissue damage... - Rapid diagnosis of smallpox infection and differentiation from its mimicsGerard J Nuovo
Department of Pathology, The Ohio State University Medical Center S305E Rhodes Hall, 450 W 10th Avenue Columbus, OH 43210, USA
Diagn Mol Pathol 12:103-7. 2003..Formalin fixation, which is optimal for in situ hybridization, guarantees the inactivation of the smallpox virus... - Verruca vulgaris of the vulva in children and adults: a nonvenereal type of vulvar wartIrene Aguilera Barrantes
Department of Pathology, The Ohio State University Medical Center, Columbus, OH, USA
Am J Surg Pathol 31:529-35. 2007..This highlights the value of HPV testing in such cases, especially if the histologic changes are consistent with verruca vulgaris... - Prospective clinical and histological study to evaluate the efficacy and safety of a targeted high-intensity narrow band UVB/UVA1 therapy for striae albaNeil S Sadick
Weill Medical College of Cornell University, New York, NY, USA
J Cosmet Laser Ther 9:79-83. 2007..The purpose of this study was to determine the efficacy and safety of a targeted narrow band UVB/UVA1 therapy for the treatment of striae alba... - Polypodium leucotomos inhibits ultraviolet B radiation-induced immunosuppressionJonathan R Siscovick
Department of Dermatology, Weill Cornell Medical College, New York, NY 10021, USA
Photodermatol Photoimmunol Photomed 24:134-41. 2008..UVB-induced murine skin cancers occur, in part, because of UVB-induced immunosuppression. Thus, we examined whether PL inhibits UVB-suppression of the induction of contact hypersensitivity (CHS) locally or systemically... - Natural killer cells contribute to the lethality of a murine model of Escherichia coli infectionBrian Badgwell
Department of Surgery, Arthur G. James Comprehensive Cancer Center, University of Buffalo, NY, USA
Surgery 132:205-12. 2002..NK-depleted mice exhibited less inflammation within multiple organs on histologic analysis. CONCLUSIONS: These results show that NK cells may contribute to the lethality of bacterial infections via effects on cytokine production... - Interleukin 1 receptor antagonist deficiency presenting as infantile pustulosis mimicking infantile pustular psoriasisKira Minkis
Department of Dermatology, Weill Medical College of Cornell University, 505 E 70th St, New York, NY 10065, USA
Arch Dermatol 148:747-52. 2012..Few studies have been published about this debilitating condition. Early identification is critical for targeted lifesaving intervention... - The histopathologic spectrum of cryofibrinogenemia in four anatomic sites. Skin, lung, muscle, and kidneyJason W Nash
Department of Pathology, Ohio State University Medical Center, Columbus, USA
Am J Clin Pathol 119:114-22. 2003..The laboratory and histologic distinctions between cryofibrinogenemia and cryoglobulinemia are addressed. We provide guidelines for the proper handling of patient specimens in the workup of cryofibrinogenemia... - Delayed and recurring blisters in the donor graft site of a burn patientRobert Anolik
Department of Dermatology, New York University, New York, NY, USA
Dermatol Online J 16:13. 2010..Normal skin has remained uninvolved. Histopathologic analysis showed a poor basement membrane zone. The patient's findings represented delayed and recurring blistering in the donor graft site that is uncommonly observed in burn patients... - Parvovirus B19-associated catastrophic endothelialitis with a Degos-like presentationMolly E Dyrsen
Dermatopathology Division, Department of Pathology, Weill Medical College Cornell, New York, NY, USA
J Cutan Pathol 35:20-5. 2008..Parvovirus B19 is a ubiquitous virus that in the majority of affected patients remains asymptomatic. Nevertheless, because of its ability to infect endothelium it can cause severe multiorgan endothelial cell injury... - Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assayMichael Chen
College of Medicine and Public Health, Ohio State University, Columbus, Ohio, USA
Appl Immunohistochem Mol Morphol 12:373-9. 2004..Although LCM appears to improve the sensitivity for detecting preneoplastic conditions, the relative specificity appears to be the same as that encountered with routine SSCP... - Pityriasis lichenoides: a clonal T-cell lymphoproliferative disorderCynthia Magro
Department of Pathology Ohio State University Medical Center, Columbus, OH 43210, USA
Hum Pathol 33:788-95. 2002.... - Incorporation of photodynamic therapy as an induction modality in non-small cell lung cancerPatrick Ross
The Ohio State University Medical Center, Division of Cardiothoracic Surgery, Columbus, Ohio, USA
Lasers Surg Med 38:881-9. 2006..CONCLUSIONS: PDT may define an alternative induction strategy for patients requiring pneumonectomy; further studies exploring the true efficacy of PDT as an induction modality are encouraged... - Cutaneous T-cell lymphoid dyscrasia: a unifying term for idiopathic chronic dermatoses with persistent T-cell clonesJoan Guitart
Department of Dermatology, Feinberg School of Medicine, Northwestern University, 676 N St Clair, Ste 1600, Chicago, IL 60611, USA
Arch Dermatol 143:921-32. 2007..Defining the preceding stages of CTCL is important to properly categorize these conditions and to help us understand and redefine the evolution of idiopathic clonal dermatoses and their potential for lymphoma progression... - Promising pharmacologic innovations in treating pulmonary fibrosisNitin Bhatt
Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Ohio State University, 201 Heart and Lung Research Institute, 473 W 12th Avenue, Columbus, OH 43210, USA
Curr Opin Pharmacol 6:284-92. 2006..The restoration of oxidant balance and inhibition of leukotrienes represent other strategies. Additionally, the role of the coagulation/fibrinolytic systems and angiogenesis has also been examined... - Pyoderma gangrenosum: a reviewA Neil Crowson
Department of Dermatology, University of Oklahoma, Tulsa, OK, USA
J Cutan Pathol 30:97-107. 2003..In this review, we describe in detail the different clinicopathologic forms of PG, summarize the diseases associated with this process in the literature and in our experience, and briefly review the treatment options... - The molecular basis of melanomagenesis and the metastatic phenotypeA Neil Crowson
Department of Dermatology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, OK 74114 4109, USA
Semin Oncol 34:476-90. 2007..These events have specific morphologic correlates that will be briefly addressed. Where relevant, we will address certain of the modern pharmacogenetic strategies that flow from these novel observations concerning melanoma biology... - Unusual histologic and clinical variants of melanoma: implications for therapyA Neil Crowson
Regional Medical Laboratories, St John Medical Center, 1923 South Utica Avenue, Tulsa, OK 74104, USA
Curr Treat Options Oncol 7:169-80. 2006..Because identification of some of these melanoma subtypes has specific implications for the therapeutic approach and some may mimic other forms of epithelial or mesenchymal neoplasia, their recognition is key to patient management... - Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejectionSusan Stewart
Papworth Everard Pathology Department, Papworth Hospital, Cambridge, UK
J Heart Lung Transplant 26:1229-42. 2007..This consensus revision of the working formulation was approved by the ISHLT board of directors in April 2007... - Granulomatous eccrinotropic lymphomatoid papulosisA Neil Crowson
Central Medical Laboratories, Winnipeg, Canada
Am J Clin Pathol 119:731-9. 2003..Our findings suggest that pruritus, a younger age at diagnosis, and a more indolent course are defining clinical features... - C3d and C4d deposition early after lung transplantationGlen P Westall
Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Monash University Medical School, Melbourne, Victoria, Australia
J Heart Lung Transplant 27:722-8. 2008..Complement staining as a predictor of antibody-mediated rejection (AMR) after lung transplantation continues to be debated... - Interstitial granulomatous dermatitis with arthritisA Neil Crowson
Hum Pathol 35:779-80. 2004 - Expression of STAT1 and STAT2 in malignant melanoma does not correlate with response to interferon-alpha adjuvant therapyGregory B Lesinski
Division of Human Cancer Genetics, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, OH 43210, USA
Cancer Immunol Immunother 54:815-25. 2005..These studies provide direct evidence to suggest that levels of STAT1 and STAT2 within the tumor do not influence a patient's response to adjuvant IFN-alpha...