Research Topics
| Julius B LucksSummaryAffiliation: Cornell University Country: USA Publications
| Collaborators
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Detail Information
Publications
Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)Julius B Lucks
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 108:11063-8. 2011....
Modeling and automation of sequencing-based characterization of RNA structureSharon Aviran
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 108:11069-74. 2011..Our results can be easily extended to other chemical probes of RNA structure, and also generalized to modeling polymerase drop-off in other sequence census-based experiments...
Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signalsLei Qi
The UC Berkeley and UCSF Graduate Program in Bioengineering, University of California, Berkeley, CA 94720, USA
Nucleic Acids Res 40:5775-86. 2012....
Rationally designed families of orthogonal RNA regulators of translationVivek K Mutalik
Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
Nat Chem Biol 8:447-54. 2012..We discuss the potential use of these regulators in next-generation synthetic biology applications...
An adaptor from translational to transcriptional control enables predictable assembly of complex regulationChang C Liu
Department of Bioengineering, University of California at Berkeley, Berkeley, California, USA
Nat Methods 9:1088-94. 2012..Continued application of our adaptor should produce large collections of transcriptional regulators whose inherent composability can facilitate the predictable engineering of complex synthetic circuits...
Why on earth?: Evaluating hypotheses about the physiological functions of human geophagySera L Young
Department of Obstetrics and Gynecology, University of California, San Francisco, California 94105, USA
Q Rev Biol 86:97-120. 2011..Our results indicate that human geophagy is best explained as providing protection from dietary chemicals, parasites, and pathogens, whereas animal geophagy may involve both micronutrient acquisition and protection...
Versatile RNA-sensing transcriptional regulators for engineering genetic networksJulius B Lucks
Department of Bioengineering, University of California, Berkeley, CA 94720, USA
Proc Natl Acad Sci U S A 108:8617-22. 2011..The combination of these three features within a single RNA-based regulatory mechanism has the potential to simplify the design and construction of genetic networks by directly propagating signals as RNA molecules...
Evolution, ecology and the engineered organism: lessons for synthetic biologyJeffrey M Skerker
Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA
Genome Biol 10:114. 2009..As the scope and complexity of synthetic biology grows, an understanding of evolution and ecology will be critical to its success...
