L Li

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Eukaryotic release factor 1-2 affects Arabidopsis responses to glucose and phytohormones during germination and early seedling development
    Xiangjun Zhou
    Robert W Holley Center for Agriculture and Health, U S Department of Agriculture Agricultural Research Service, Cornell University, Ithaca, NY 14853, USA
    J Exp Bot 61:357-67. 2010
  2. pmc Proteomic analysis of chromoplasts from six crop species reveals insights into chromoplast function and development
    Yong qiang Wang
    Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA
    J Exp Bot 64:949-61. 2013
  3. doi request reprint Chromoplast biogenesis and carotenoid accumulation
    Li Li
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA Electronic address
    Arch Biochem Biophys 539:102-9. 2013
  4. doi request reprint The Or gene enhances carotenoid accumulation and stability during post-harvest storage of potato tubers
    Li Li
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
    Mol Plant 5:339-52. 2012
  5. pmc Transcriptome analysis of ectopic chloroplast development in green curd cauliflower (Brassica oleracea L. var. botrytis)
    Xiangjun Zhou
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
    BMC Plant Biol 11:169. 2011
  6. ncbi request reprint High-resolution genetic and physical mapping of the cauliflower high-beta-carotene gene Or ( Orange)
    L Li
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Mol Genet Genomics 270:132-8. 2003
  7. ncbi request reprint beta-Carotene accumulation induced by the cauliflower Or gene is not due to an increased capacity of biosynthesis
    Li Li
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Phytochemistry 67:1177-84. 2006
  8. ncbi request reprint Overexpression of polyphenol oxidase in transgenic tomato plants results in enhanced bacterial disease resistance
    Li Li
    Department of Plant Breeding and Biometry, 252 Emerson Hall, Cornell University, Ithaca, NY 14853 2901, USA Fax 1 607 2551132
    Planta 215:239-47. 2002
  9. ncbi request reprint Metabolic engineering of carotenoid accumulation by creating a metabolic sink
    Li Li
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Transgenic Res 16:581-5. 2007
  10. doi request reprint Phytoene desaturase is present in a large protein complex in the plastid membrane
    Alex B Lopez
    United States Department of Agriculture Agriculture Research Service, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Physiol Plant 133:190-8. 2008

Collaborators

Detail Information

Publications73

  1. pmc Eukaryotic release factor 1-2 affects Arabidopsis responses to glucose and phytohormones during germination and early seedling development
    Xiangjun Zhou
    Robert W Holley Center for Agriculture and Health, U S Department of Agriculture Agricultural Research Service, Cornell University, Ithaca, NY 14853, USA
    J Exp Bot 61:357-67. 2010
    ..Collectively, these data provide evidence in support of a novel role of eRF1-2 in affecting glucose and phytohormone responses in modulating plant growth and development...
  2. pmc Proteomic analysis of chromoplasts from six crop species reveals insights into chromoplast function and development
    Yong qiang Wang
    Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA
    J Exp Bot 64:949-61. 2013
    ..This work provides reference datasets for future experimental study of chromoplast biogenesis, development, and regulation in plants...
  3. doi request reprint Chromoplast biogenesis and carotenoid accumulation
    Li Li
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA Electronic address
    Arch Biochem Biophys 539:102-9. 2013
    ..The objective of this review is to provide an integrated view on our understanding of chromoplast biogenesis and carotenoid accumulation in plants...
  4. doi request reprint The Or gene enhances carotenoid accumulation and stability during post-harvest storage of potato tubers
    Li Li
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
    Mol Plant 5:339-52. 2012
    ..Our findings suggest that induction of a proper sink structure formation in staple crops may provide the crops with a unique ability to promote and/or stabilize provitamin A accumulation during plant growth and post-harvest storage...
  5. pmc Transcriptome analysis of ectopic chloroplast development in green curd cauliflower (Brassica oleracea L. var. botrytis)
    Xiangjun Zhou
    Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
    BMC Plant Biol 11:169. 2011
    ..Despite extensive studies of this process, the genetic basis and the regulatory control of chloroplast biogenesis and development remain to be elucidated...
  6. ncbi request reprint High-resolution genetic and physical mapping of the cauliflower high-beta-carotene gene Or ( Orange)
    L Li
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Mol Genet Genomics 270:132-8. 2003
    ..Physical mapping delimited the Or locus to a 50-kb DNA fragment within a single BAC clone, which corresponds to a genetic interval of 0.3 cM...
  7. ncbi request reprint beta-Carotene accumulation induced by the cauliflower Or gene is not due to an increased capacity of biosynthesis
    Li Li
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Phytochemistry 67:1177-84. 2006
    ..These results suggest that Or-induced beta-carotene accumulation does not result from an increased capacity of carotenoid biosynthesis...
  8. ncbi request reprint Overexpression of polyphenol oxidase in transgenic tomato plants results in enhanced bacterial disease resistance
    Li Li
    Department of Plant Breeding and Biometry, 252 Emerson Hall, Cornell University, Ithaca, NY 14853 2901, USA Fax 1 607 2551132
    Planta 215:239-47. 2002
    ..These results demonstrate the importance of PPO-mediated phenolic oxidation in restricting plant disease development...
  9. ncbi request reprint Metabolic engineering of carotenoid accumulation by creating a metabolic sink
    Li Li
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Transgenic Res 16:581-5. 2007
    ..Manipulation of the formation of metabolic sink along with the catalytic activity of the pathway may represent a promising strategy for maximally improving the nutritional quality of food crops...
  10. doi request reprint Phytoene desaturase is present in a large protein complex in the plastid membrane
    Alex B Lopez
    United States Department of Agriculture Agriculture Research Service, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Physiol Plant 133:190-8. 2008
    ..The plastid membrane form was present in a large protein complex of approximately 350 kDa, whereas the stroma version was in an approximately 660 kDa complex...
  11. ncbi request reprint A novel gene mutation that confers abnormal patterns of beta-carotene accumulation in cauliflower (Brassica oleracea var. botrytis)
    L Li
    USDA-ARS, U.S. Plant, Soil and Nutrition Laboratory, Tower Road, Ithaca, NY 14853, USA
    Plant J 26:59-67. 2001
    ..Our results suggest that the Or gene may induce carotenoid accumulation by initiating the synthesis of a carotenoid deposition sink in the form of the large carotenoid-sequestering sheets...
  12. ncbi request reprint Modulation of carotenoid accumulation in transgenic potato by inducing chromoplast formation with enhanced sink strength
    Joyce Van Eck
    Thompson Institute for Plant Research, Cornell University, Ithaca, NY, USA
    Methods Mol Biol 643:77-93. 2010
    ..In this chapter, we describe a detailed protocol for metabolic engineering of carotenoids in potato plants with the Or gene and the analysis of the Or transformants...
  13. doi request reprint Effect of the cauliflower Or transgene on carotenoid accumulation and chromoplast formation in transgenic potato tubers
    Alex B Lopez
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    J Exp Bot 59:213-23. 2008
    ..Collectively, these results provide direct evidence demonstrating that the Or gene indeed controls chromoplast differentiation and that regulation of chromoplast formation can have a profound effect on carotenoid accumulation in plants...
  14. ncbi request reprint Molecular mapping of Or, a gene inducing beta-carotene accumulation in cauliflower (Brassica oleracea L. var. botrytis)
    L Li
    United States Department of Agriculture Agruculture Research Service USDA ARS, Plant, Soil, and Nutrition Laboratory, Cornell University, Ithca, NY 14853, USA
    Genome 46:588-94. 2003
    ..These PCR-based markers will be useful for a large-scale application in facilitating the positional cloning of the Or gene...
  15. doi request reprint Use of the cauliflower Or gene for improving crop nutritional quality
    Xiangjun Zhou
    U S Department of Agriculture Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA
    Biotechnol Annu Rev 14:171-90. 2008
    ..Thus, the Or gene offers a new molecular tool to complement current approaches for nutritional enhancement in agriculturally important crops...
  16. doi request reprint Transcriptional regulation of anthocyanin biosynthesis in red cabbage
    Youxi Yuan
    Department of Plant Breeding and Genetics, Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY, 14853, USA
    Planta 230:1141-53. 2009
    ..Moreover, the amount of total anthocyanins in red cabbage was found to be positively correlated with total antioxidant power, implicating the potential health benefit of red cabbage to human health...
  17. pmc Involvement of a broccoli COQ5 methyltransferase in the production of volatile selenium compounds
    Xin Zhou
    Robert W Holley Center for Agriculture and Health, United States Department of Agriculture Agricultural Research Service, Cornell University, Ithaca, New York 14853, USA
    Plant Physiol 151:528-40. 2009
    ..This discovery opens up new prospects regarding our understanding of the complete metabolism of Se and may lead to ways to modify Se-accumulator plants with increased efficiency for phytoremediation of Se-contaminated environments...
  18. ncbi request reprint Biochemical and molecular characterization of the homocysteine S-methyltransferase from broccoli (Brassica oleracea var. italica)
    Sangbom M Lyi
    USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
    Phytochemistry 68:1112-9. 2007
    ....
  19. pmc The cauliflower Or gene encodes a DnaJ cysteine-rich domain-containing protein that mediates high levels of beta-carotene accumulation
    Shan Lu
    U S Department of Agriculure Agricultural Research Service, Plant, Soil, and Nutrition Laboratory, Cornell University, Ithaca, New York 14853, USA
    Plant Cell 18:3594-605. 2006
    ..We show here that controlling the formation of chromoplasts is an important mechanism by which carotenoid accumulation is regulated in plants...
  20. pmc Molecular and biochemical characterization of the selenocysteine Se-methyltransferase gene and Se-methylselenocysteine synthesis in broccoli
    Sangbom M Lyi
    United States Department of Agriculture Agricultural Research Service, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, New York 14853, USA
    Plant Physiol 138:409-20. 2005
    ..Our results reveal that SeMSC accumulation closely correlated with the BoSMT gene expression and the total Se status in tissues and provide important information for maximizing the SeMSC production in this beneficial vegetable plant...
  21. ncbi request reprint Development of an integrated approach for evaluation of 2-D gel image analysis: impact of multiple proteins in single spots on comparative proteomics in conventional 2-D gel/MALDI workflow
    Yong Yang
    US Plant, Soil and Nutrition Laboratory, USDA ARS, Ithaca, NY, USA
    Electrophoresis 28:2080-94. 2007
    ..Here, the new approach is proposed as an alternative to traditional gel-based quantitative proteomics studies...
  22. pmc Illuminating solution responses of a LOV domain protein with photocoupled small-angle X-ray scattering
    Jessica S Lamb
    School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
    J Mol Biol 393:909-19. 2009
    ..Envelope reconstructions of the transient light-state dimer reveal structures that are best described by a parallel arrangement of subunits that have significantly changed conformation compared to the crystal structure...
  23. pmc DNA variation at the invertase locus invGE/GF is associated with tuber quality traits in populations of potato breeding clones
    Li Li
    Max Planck Institut fur Zuchtungsforschung, Koln, Germany
    Genetics 170:813-21. 2005
    ....
  24. ncbi request reprint Molecular characterization of cotton GhTUA9 gene specifically expressed in fibre and involved in cell elongation
    Li Li
    College of Life Sciences, Huazhong Normal University, Wuhan 430079, China
    J Exp Bot 58:3227-38. 2007
    ..4-1.7-fold, indicating that the GhTUA9 gene is involved in cell elongation. Given all the above results, it is proposed that the GhTUA9 gene may play an important role in fibre elongation...
  25. ncbi request reprint [SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine]
    Jian chen Fang
    Department of Pathology the Third Hospital, Sun Yat Sen University, Guangzhou 510630, China
    Zhonghua Xue Ye Xue Za Zhi 27:670-4. 2006
    ..To explore the transcription regulation of 5-aza-2'-deoxycytidine(5-Aza-CdR) on SHP-1 gene and its effects on Daudi cell line growth...
  26. pmc Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells
    Jacqueline M Kraveka
    Division of Hematology Oncology, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Biol Chem 282:16718-28. 2007
    ..Tautomycin was also able to block the hypophosphorylation of the retinoblastoma protein observed upon fenretinide treatment. These findings suggest a novel biological function for dihydroceramides...
  27. ncbi request reprint [Inhibitory effects of RNA interference on expression of matrix metalloproteinase-9 gene and invasiveness and adhesion in ovarian cancer cells]
    Xiao xia Hu
    Department of Gynecology Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
    Zhonghua Fu Chan Ke Za Zhi 41:579-83. 2006
    ..To investigate the inhibitory effects of RNA interference (RNAi) on the expression of matrix metalloproteinase-9 (MMP-9) gene and invasiveness and adhesion of ovarian cancer cells...
  28. ncbi request reprint Thalassospira xiamenensis sp. nov. and Thalassospira profundimaris sp. nov
    Chenli Liu
    Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, PR China
    Int J Syst Evol Microbiol 57:316-20. 2007
    ..nov. (type strain, M-5T=DSM 17429T=CGMCC 1.3998T) and Thalassospira profundimaris sp. nov. (type strain, WP0211T=DSM 17430T=CGMCC 1.3997T) are proposed...
  29. ncbi request reprint [Inhibitory effects of antisense MMP-9 oligodeoxynucleotides on invasiveness and adherence of ovarian cancer cells]
    Xiao xia Hu
    Department of Gynecological Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
    Zhonghua Zhong Liu Za Zhi 28:662-5. 2006
    ..To observe the inhibitory effects of antisense MMP-9 oligodeoxynucleotides on invasiveness and adhesion ability in vitro of ovarian cancer cells, and to investigate the mechanisms of action...
  30. ncbi request reprint Mapping a novel locus for familial atrial fibrillation on chromosome 10p11-q21
    Paul G A Volders
    Department of Cardiology, Academic Hospital Maastricht, Maastricht, The Netherlands
    Heart Rhythm 4:469-75. 2007
    ..2 million Americans. Recently, several chromosomal loci and genes have been found to be associated with familial AF. However, in most other AF cases, the genetic basis is still poorly understood...
  31. ncbi request reprint Impaired innate immunity of ocular surface is the key bridge between extended contact lens wearing and occurrence of Acanthamoeba keratitis
    Li Li
    Beijing Institute of Ophthalmology, Beijing Tongren Ophthalmic Center, Capital University of Medical Sciences, 17 Hou Gou Lane, Chong Nei Street, Beijing 100005, PR China
    Med Hypotheses 70:260-4. 2008
    ..Understanding the immunological mechanism of extended contact lens wearing on the A. keratitis may give more contributions on the research of the disease, and facilitate the production of contact lens with much higher biocompatibility...
  32. doi request reprint Assembly of beta-cyclodextrin with 3S-tetrahydro-beta-carboline-3-carboxylic acid and self-assembly of 6-(3'S-carboline-3'-carboxylaminoethylamino)-6-deoxy-beta-cyclodextrin: approaches to enhance anti-oxidation stability and anti-thrombotic potency
    Li Li
    College of Pharmaceutical Sciences, Capital Medical Univesity, Beijing 100069, PR China
    J Phys Chem B 112:12139-47. 2008
    ..The significant improvement of the bioactivity and stability of THCA indicates that inclusion complexation and conjugation with beta-CD provide promising approaches to improve the practical use of THCA in clinical applications...
  33. pmc Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2
    Kyriacos N Felekkis
    Department of Biological Sciences, University of Cyprus, Cyprus
    BMC Nephrol 9:10. 2008
    ....
  34. ncbi request reprint Carotenoid metabolism: biosynthesis, regulation, and beyond
    Shan Lu
    State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China
    J Integr Plant Biol 50:778-85. 2008
    ....
  35. pmc Modulation of brassinosteroid-regulated gene expression by Jumonji domain-containing proteins ELF6 and REF6 in Arabidopsis
    Xiaofei Yu
    Department of Genetics, Development and Cell Biology, Plant Science Institute, Iowa State University, Ames, IA 50011, USA
    Proc Natl Acad Sci U S A 105:7618-23. 2008
    ..Thus, our study establishes an important mechanism by which Jmj domain proteins modulate specific gene expression by interacting with pathway-specific transcription factors such as BES1...
  36. ncbi request reprint Molecular cloning and characterization of a new cDNA encoding hyoscyamine 6beta-hydroxylase from roots of Anisodus acutangulus
    Guoyin Kai
    Laboratory of Plant Biotechnology, College of Life and Environment Sciences, Shanghai Normal University, Shanghai 200234, People s Republic of China
    J Biochem Mol Biol 40:715-22. 2007
    ....
  37. ncbi request reprint Transmission of Rice stripe virus acquired from frozen infected leaves by the small brown planthopper (Laodelphax striatellus Fallen)
    Shixian Zhang
    State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agriculture Sciences, No 2 West Yuanmingyuan Road, Beijing 100094, China
    J Virol Methods 146:359-62. 2007
    ..67%) became infected, compared to 7 of 30 plants (23.33%) became infected when a single insect fed on fresh infected leaves. All rice plants expressing stripe symptoms were identified with the virus by RT-PCR...
  38. ncbi request reprint [Expression of mineralocorticoid receptor and 11-beta-hydroxysteroid dehydrogenase type 2 in human atria during chronic atrial fibrillation: study of 25 cases]
    De an Pei
    Department of Cardiothoracic Surgery, Changhai Hospital, Secondary Military Medical University, Shanghai 200433, China
    Zhonghua Yi Xue Za Zhi 87:816-9. 2007
    ....
  39. ncbi request reprint [The mouse ovarian surface epithelium cells (MOSE) transformation induced by c-myc/K-ras in]
    De Sheng Yao
    Department of Gynecological Oncology, Affiliated Cancer Hospital of Guangxi Medical University, Nanning 530021, China
    Zhonghua Zhong Liu Za Zhi 28:881-5. 2006
    ..To study the function of c-myc and K-ras in tumorigenesis of ovarian cancer...
  40. pmc Nearly identical paralogs: implications for maize (Zea mays L.) genome evolution
    Scott J Emrich
    Interdepartmental Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, Iowa 50011, USA
    Genetics 175:429-39. 2007
    ..As such, NIPs may have played important roles during the evolution and domestication of maize and may contribute to the success of long-term selection experiments in this important crop species...
  41. pmc Gene discovery and annotation using LCM-454 transcriptome sequencing
    Scott J Emrich
    Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, IA 50010, USA
    Genome Res 17:69-73. 2007
    ..We conclude that the coupling of LCM and 454 sequencing technologies facilitates the discovery of rare, possibly cell-type-specific transcripts...
  42. ncbi request reprint Identification of an alternatively processed nicotinic receptor alpha7 subunit RNA in mouse brain
    Philip A Saragoza
    Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109 0930, USA
    Brain Res Mol Brain Res 117:15-26. 2003
    ..The variant alpha7 subunit was also found to act as a dominant-negative effecter of normal alpha7 subunit function...
  43. ncbi request reprint Reconstitution of CD40 and CD80 in dendritic cells generated from blasts of patients with acute myeloid leukemia
    Li Li
    Third Department of Internal Medicine, University of Ulm, Ulm, Germany
    Cancer Immun 3:8. 2003
    ..AML-DCs express at least one LAA and strongly express HLA and costimulatory molecules, the prerequisites for eliciting T cell responses. AML-DCs may play a role in vaccine-based immunotherapies for AML patients...
  44. ncbi request reprint Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetes
    Illarion V Turko
    Department of Integrative Biology and Pharmacology, Univeristy of Texas Medical School, Houston, 77030, USA
    J Biol Chem 278:33972-7. 2003
    ....
  45. ncbi request reprint [A study of susceptibility genes mapping for aberrant B1 cell proliferation in New Zealand mice]
    Wei guo Xiao
    Department of Hematology, The First Affiliated Hospital, China Medical University, Shenyang 110001, China
    Zhonghua Nei Ke Za Zhi 42:38-40. 2003
    ..To map the susceptibility genes for aberrant B1 cell proliferation in New Zealand mice...
  46. ncbi request reprint [Screening and cloning gene of hepatocyte protein interacting with hepatitis C virus core protein]
    Ke Li
    Gene Theraphy Research Center, Institute of Infectious Diseases, The 302nd Hospital of PLA, Beijing 100039, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 16:351-3. 2002
    ..To clone the unknown gene of hepatocyte protein interacting with hepatitis C virus core protein...
  47. ncbi request reprint [Cloning and sequencing of fragments associated with cytoplasm male sterility of rice]
    Jian bo Yang
    Key Lab of Rice Genetics and Breeding, Ministry of Agriculture, Anhui Academy of Agricultural Sciences, Hefei 230031, China
    Yi Chuan Xue Bao 29:808-13. 2002
    ..The similarity ratios were 97% and 100%. It was inferred that the possible position of PWH-17 in rice (wild abortive) could be located between tRNA-Asp and Cox II, which will be discussed further...
  48. ncbi request reprint Human SM22 alpha BAC encompasses regulatory sequences for expression in vascular and visceral smooth muscles at fetal and adult stages
    Rui Xu
    Department of Internal Medicine, Wayne State University, Detroit, Michigan 48201, USA
    Am J Physiol Heart Circ Physiol 284:H1398-407. 2003
    ....
  49. pmc PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data
    Amit Bahl
    Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Nucleic Acids Res 31:212-5. 2003
    ..The software used to develop PlasmoDB has been used to create a second Apicomplexan parasite genome database, ToxoDB (http://ToxoDB.org)...
  50. ncbi request reprint Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotides
    Chunyao Xia
    Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, California 94115, USA
    Mol Cancer Ther 1:687-94. 2002
    ..Down-regulation of survivin by a targeted antisense oligonucleotide appears to be an effective gene therapy approach to the treatment of mesothelioma...
  51. ncbi request reprint PTEN regulation of neural development and CNS stem cells
    Li Li
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    J Cell Biochem 88:24-8. 2003
    ..Collectively, these studies demonstrate that PTEN does much more than suppressing tumors. It is a master regulator in developing and adult brain...
  52. ncbi request reprint Distinct response of human B cell subpopulations in recognition of an innate immune signal, CpG DNA
    Jaeho Jung
    Laboratory of Cellular Immunology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
    J Immunol 169:2368-73. 2002
    ..These results suggest that CpG DNA potentiates the B cell adaptive immune response by enhancing terminal differentiation, but does not affect the generation of memory B cells...
  53. ncbi request reprint Pathway of oxidative folding of alpha-lactalbumin: a model for illustrating the diversity of disulfide folding pathways
    Jui Yoa Chang
    Research Center for Protein Chemistry, Institute of Molecular Medicine and Department of Biochemistry and Molecular Biology, The University of Texas, Houston, Texas 77030, USA
    Biochemistry 41:8405-13. 2002
    ..Our study also reveals novel aspects of the folding mechanism of alpha LA that have not been described previously...
  54. ncbi request reprint NF-kappaB-mediated up-regulation of Bcl-X(S) and Bax contributes to cytochrome c release in cyanide-induced apoptosis
    Yan Shou
    Neurotoxicology Laboratory, Department of Medicinal Chemistry and Molecular Pharmacology, Department of Basic Medical Sciences, Purdue University, West Lafayette, IN 47907 1333, USA
    J Neurochem 81:842-52. 2002
    ..It was concluded that NF-kappaB-mediated up-regulation of Bcl-X(S) and Bax is involved in regulating cytochrome c release in cyanide-induced apoptosis...
  55. ncbi request reprint A draft sequence of the rice genome (Oryza sativa L. ssp. indica)
    Jun Yu
    Beijing Genomics Institute Center of Genomics and Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China
    Science 296:79-92. 2002
    ..4% of predicted rice genes had a homolog in A. thaliana. The large proportion of rice genes with no recognizable homologs is due to a gradient in the GC content of rice coding sequences...
  56. ncbi request reprint Cloning and expression of the gene of augmenter of liver regeneration in yeast cells
    Jun Cheng
    Gene Therapy Research Center, Institute of Infectious Diseases, 302 Hospital of PLA, Beijing 100039, China
    Hepatobiliary Pancreat Dis Int 1:87-91. 2002
    ..To study the function of augmenter of liver regeneration (ALR) as a regulatory factor that specifically stimulates hepatic cell regeneration, we constructed yeast expressive vector of ALR and expressed it in yeast cells...
  57. ncbi request reprint Alternative promoters and polyadenylation regulate tissue-specific expression of Hemogen isoforms during hematopoiesis and spermatogenesis
    Li V Yang
    Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA
    Dev Dyn 228:606-16. 2003
    ..Finally, fluorescence in situ hybridization demonstrates that HEMGN is localized to chromosome 4 A5-B2 in mouse and to chromosome 9q22 in human, which is a region known to harbor a cluster of leukemia breakpoints...
  58. ncbi request reprint [Refolding and purification of Plasmodium falciparum glutamate dehydrogenase fusion protein]
    Yan Li
    Institute of Tropical Medicine, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 23:1273-6. 2003
    ..To establish the method for renaturation and purification of the fusion protein of Plasmodium falfiparum (FCC1/HN ) glutamate dehydrogenase (GDH) with glutathione S-transferase (GST)...
  59. ncbi request reprint Polyphenolic profiles and antioxidant activities of heartnut (Juglans ailanthifolia Var. cordiformis) and Persian walnut (Juglans regia L.)
    Li Li
    Department of Chemistry, Changchun Normal College, Changchun 130032, China
    J Agric Food Chem 54:8033-40. 2006
    ..These components were found to contribute to the strong total antioxidant activities measured using ferric reducing antioxidant power and photochemiluminescence methods...
  60. ncbi request reprint Uveal melanocytes do not respond to or express receptors for alpha-melanocyte-stimulating hormone
    Li Li
    Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0592, USA
    Invest Ophthalmol Vis Sci 47:4507-12. 2006
    ..This study was designed to examine the evidence that alpha-melanocyte-stimulating hormone (alpha-MSH), which is thought to be the mediator of UV response in the skin, has any role to play in uveal melanocytes...
  61. ncbi request reprint A brassinolide-suppressed rice MADS-box transcription factor, OsMDP1, has a negative regulatory role in BR signaling
    Ke Duan
    Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, 20 Nanxincun Road, 100093 Beijing, China
    Plant J 47:519-31. 2006
    ....
  62. ncbi request reprint Enhanced cell survival of Hep3B cells by the hepatitis B x antigen effector, URG11, is associated with upregulation of beta-catenin
    Zhaorui Lian
    Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Hepatology 43:415-24. 2006
    ..These observations also suggest that URG11 may be a regulatory element in the beta-catenin signaling pathway and may be a target for chemoprevention of HCC...
  63. ncbi request reprint Functional analysis of a reproductive organ predominant expressing promoter in cotton plants
    Maozhi Ren
    Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China
    Sci China C Life Sci 48:452-9. 2005
    ..The results showed that the arf1 promoter was a typical reproductive organ-specific promoter. Hopefully, the arf1 promoter can be a regulatory element for designing cotton reproductive organs with desired characteristics...
  64. pmc Brassinosteroids stimulate plant tropisms through modulation of polar auxin transport in Brassica and Arabidopsis
    Li Li
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032 Shanghai, China
    Plant Cell 17:2738-53. 2005
    ....
  65. ncbi request reprint Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells
    Yanhong Gao
    Laboratory of Stem Cell Biology, Beijing Institute of Transfusion Medicine, 27 Taiping Road, Beijing 100850, PR China
    Biochem Biophys Res Commun 335:343-50. 2005
    ..Furthermore, overexpressed spindlin1 cells formed colonies in soft agar in vitro and formed tumors in nude mice. Our findings provide direct evidence that spindlin1 gene may contribute to tumorigenesis...
  66. ncbi request reprint [Study on the expression and mutation of cadherin 6 gene in human ovarian carcinoma]
    Dan Rong Li
    Department of Basic Science, Cancer Institute of Guangxi Zhuang Automomous Region, Nanning 530021, China
    Zhonghua Fu Chan Ke Za Zhi 39:616-9. 2004
    ..To study expression and mutation of cadherin 6 gene in human ovarian tumor tissues and its clinical significance and to explore new molecular biomarker of ovarian tumors...
  67. ncbi request reprint Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates
    Li Li
    Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot 76100, Israel
    Development 131:5277-86. 2004
    ....
  68. ncbi request reprint [Reversal of multidrug resistance of MCF-7/ADR in nude mice by grape seed polyphenol]
    Cui Juan Zhang
    Department of Pathology, Medical School of Shandong University, Jinan 250012, China
    Zhonghua Wai Ke Za Zhi 42:795-8. 2004
    ..To study the reversing effect of Grape seed polyphenol (GSP) on multidrug resistance of MCF-7/ADR cell in vivo...
  69. pmc Comparative mapping of a major aluminum tolerance gene in sorghum and other species in the poaceae
    Jurandir V Magalhaes
    U S Plant Soil and Nutrition Laboratory, U S Department of Agriculture Agricultural Research Service, Cornell University, Ithaca, New York 14853, USA
    Genetics 167:1905-14. 2004
    ..Therefore, this study demonstrates a clear evolutionary link between genes and QTL encoding the same trait in distantly related species within a single plant family...
  70. ncbi request reprint Development and characterization of five cell models for chemoresistance studies of human ovarian carcinoma
    Li Li
    Department of Gynecologic Oncology, Medical University of Guangxi Cancer Institute and Hospital, Nanning 530021, P R China
    Int J Mol Med 14:257-64. 2004
    ..Taken together, our findings indicate that these models may be potentially used to assess the biochemical and genetic mechanisms of drug resistance in human ovarian cancer and to identify new drug resistance-related genes...
  71. ncbi request reprint Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism
    Li Li
    Immunology Group, Institute of Cell and Molecular Sciences, St Barts and The Royal London School of Medicine, 59 Bartholomew s Close, London EC1A 7ED, United Kingdom
    J Biol Chem 279:34107-14. 2004
    ..Therefore, our results indicate that SOCS-6 may provide a dynamically regulated mechanism by which insulin can transiently overcome the negative effects that p85 monomers have on signaling via PI 3-kinase-dependent signaling pathways...
  72. pmc Differential expression of thromboxane synthase in prostate carcinoma: role in tumor cell motility
    Daotai Nie
    Department of Radiation Oncology, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, Michigan 48202, USA
    Am J Pathol 164:429-39. 2004
    ..Finally, increased expression of TxS in DU145 cells increased cell motility. Our data suggest that human PCa cells express TxS and that this enzyme may contribute to PCa progression through modulating cell motility...
  73. ncbi request reprint Activation of K(+) channels and increased migration of differentiated intestinal epithelial cells after wounding
    Jaladanki N Rao
    Department of Surgery, University of Maryland School of Medicine, 10 North Greene Street, Baltimore, MD 21201, USA
    Am J Physiol Cell Physiol 282:C885-98. 2002
    ..These results suggest that increased migration of differentiated intestinal epithelial cells is mediated, at least partially, by increasing Kv channel activity and Ca(2+) influx during restitution...