Research Topics
| L LiSummaryAffiliation: Cornell University Country: USA Publications
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Publications
The Or gene enhances carotenoid accumulation and stability during post-harvest storage of potato tubersLi Li
Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
Mol Plant 5:339-52. 2012..Our findings suggest that induction of a proper sink structure formation in staple crops may provide the crops with a unique ability to promote and/or stabilize provitamin A accumulation during plant growth and post-harvest storage...
Transcriptome analysis of ectopic chloroplast development in green curd cauliflower (Brassica oleracea L. var. botrytis)Xiangjun Zhou
Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY 14853, USA
BMC Plant Biol 11:169. 2011..Despite extensive studies of this process, the genetic basis and the regulatory control of chloroplast biogenesis and development remain to be elucidated...
Metabolic engineering of carotenoid accumulation by creating a metabolic sinkLi Li
USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
Transgenic Res 16:581-5. 2007..Manipulation of the formation of metabolic sink along with the catalytic activity of the pathway may represent a promising strategy for maximally improving the nutritional quality of food crops...
Overexpression of polyphenol oxidase in transgenic tomato plants results in enhanced bacterial disease resistanceLi Li
Department of Plant Breeding and Biometry, 252 Emerson Hall, Cornell University, Ithaca, NY 14853 2901, USA Fax 1 607 2551132
Planta 215:239-47. 2002..These results demonstrate the importance of PPO-mediated phenolic oxidation in restricting plant disease development...
High-resolution genetic and physical mapping of the cauliflower high-beta-carotene gene Or ( Orange)L Li
USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
Mol Genet Genomics 270:132-8. 2003..Physical mapping delimited the Or locus to a 50-kb DNA fragment within a single BAC clone, which corresponds to a genetic interval of 0.3 cM...
beta-Carotene accumulation induced by the cauliflower Or gene is not due to an increased capacity of biosynthesisLi Li
USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
Phytochemistry 67:1177-84. 2006..These results suggest that Or-induced beta-carotene accumulation does not result from an increased capacity of carotenoid biosynthesis...
Phytoene desaturase is present in a large protein complex in the plastid membraneAlex B Lopez
United States Department of Agriculture Agriculture Research Service, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
Physiol Plant 133:190-8. 2008..The plastid membrane form was present in a large protein complex of approximately 350 kDa, whereas the stroma version was in an approximately 660 kDa complex...
A novel gene mutation that confers abnormal patterns of beta-carotene accumulation in cauliflower (Brassica oleracea var. botrytis)L Li
USDA-ARS, U.S. Plant, Soil and Nutrition Laboratory, Tower Road, Ithaca, NY 14853, USA
Plant J 26:59-67. 2001..Our results suggest that the Or gene may induce carotenoid accumulation by initiating the synthesis of a carotenoid deposition sink in the form of the large carotenoid-sequestering sheets...
Modulation of carotenoid accumulation in transgenic potato by inducing chromoplast formation with enhanced sink strengthJoyce Van Eck
Thompson Institute for Plant Research, Cornell University, Ithaca, NY, USA
Methods Mol Biol 643:77-93. 2010..In this chapter, we describe a detailed protocol for metabolic engineering of carotenoids in potato plants with the Or gene and the analysis of the Or transformants...
Effect of the cauliflower Or transgene on carotenoid accumulation and chromoplast formation in transgenic potato tubersAlex B Lopez
USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
J Exp Bot 59:213-23. 2008..Collectively, these results provide direct evidence demonstrating that the Or gene indeed controls chromoplast differentiation and that regulation of chromoplast formation can have a profound effect on carotenoid accumulation in plants...
Molecular mapping of Or, a gene inducing beta-carotene accumulation in cauliflower (Brassica oleracea L. var. botrytis)L Li
United States Department of Agriculture Agruculture Research Service USDA ARS, Plant, Soil, and Nutrition Laboratory, Cornell University, Ithca, NY 14853, USA
Genome 46:588-94. 2003..These PCR-based markers will be useful for a large-scale application in facilitating the positional cloning of the Or gene...
Transcriptional regulation of anthocyanin biosynthesis in red cabbageYouxi Yuan
Department of Plant Breeding and Genetics, Robert W Holley Center for Agriculture and Health, USDA ARS, Cornell University, Ithaca, NY, 14853, USA
Planta 230:1141-53. 2009..Moreover, the amount of total anthocyanins in red cabbage was found to be positively correlated with total antioxidant power, implicating the potential health benefit of red cabbage to human health...
Use of the cauliflower Or gene for improving crop nutritional qualityXiangjun Zhou
U S Department of Agriculture Department of Plant Breeding and Genetics, Cornell University, Ithaca, NY 14853, USA
Biotechnol Annu Rev 14:171-90. 2008..Thus, the Or gene offers a new molecular tool to complement current approaches for nutritional enhancement in agriculturally important crops...
Involvement of a broccoli COQ5 methyltransferase in the production of volatile selenium compoundsXin Zhou
Robert W Holley Center for Agriculture and Health, United States Department of Agriculture Agricultural Research Service, Cornell University, Ithaca, New York 14853, USA
Plant Physiol 151:528-40. 2009..This discovery opens up new prospects regarding our understanding of the complete metabolism of Se and may lead to ways to modify Se-accumulator plants with increased efficiency for phytoremediation of Se-contaminated environments...
Biochemical and molecular characterization of the homocysteine S-methyltransferase from broccoli (Brassica oleracea var. italica)Sangbom M Lyi
USDA ARS, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, NY 14853, USA
Phytochemistry 68:1112-9. 2007....
The cauliflower Or gene encodes a DnaJ cysteine-rich domain-containing protein that mediates high levels of beta-carotene accumulationShan Lu
U S Department of Agriculure Agricultural Research Service, Plant, Soil, and Nutrition Laboratory, Cornell University, Ithaca, New York 14853, USA
Plant Cell 18:3594-605. 2006..We show here that controlling the formation of chromoplasts is an important mechanism by which carotenoid accumulation is regulated in plants...
Molecular and biochemical characterization of the selenocysteine Se-methyltransferase gene and Se-methylselenocysteine synthesis in broccoliSangbom M Lyi
United States Department of Agriculture Agricultural Research Service, Plant, Soil and Nutrition Laboratory, Cornell University, Ithaca, New York 14853, USA
Plant Physiol 138:409-20. 2005..Our results reveal that SeMSC accumulation closely correlated with the BoSMT gene expression and the total Se status in tissues and provide important information for maximizing the SeMSC production in this beneficial vegetable plant...
Eukaryotic release factor 1-2 affects Arabidopsis responses to glucose and phytohormones during germination and early seedling developmentXiangjun Zhou
Robert W Holley Center for Agriculture and Health, U S Department of Agriculture Agricultural Research Service, Cornell University, Ithaca, NY 14853, USA
J Exp Bot 61:357-67. 2010..Collectively, these data provide evidence in support of a novel role of eRF1-2 in affecting glucose and phytohormone responses in modulating plant growth and development...
Illuminating solution responses of a LOV domain protein with photocoupled small-angle X-ray scatteringJessica S Lamb
School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
J Mol Biol 393:909-19. 2009..Envelope reconstructions of the transient light-state dimer reveal structures that are best described by a parallel arrangement of subunits that have significantly changed conformation compared to the crystal structure...
Development of an integrated approach for evaluation of 2-D gel image analysis: impact of multiple proteins in single spots on comparative proteomics in conventional 2-D gel/MALDI workflowYong Yang
US Plant, Soil and Nutrition Laboratory, USDA ARS, Ithaca, NY, USA
Electrophoresis 28:2080-94. 2007..Here, the new approach is proposed as an alternative to traditional gel-based quantitative proteomics studies...
DNA variation at the invertase locus invGE/GF is associated with tuber quality traits in populations of potato breeding clonesLi Li
, , Germany
Genetics 170:813-21. 2005....
Molecular characterization of cotton GhTUA9 gene specifically expressed in fibre and involved in cell elongationLi Li
College of Life Sciences, Huazhong Normal University, Wuhan 430079, China
J Exp Bot 58:3227-38. 2007..4-1.7-fold, indicating that the GhTUA9 gene is involved in cell elongation. Given all the above results, it is proposed that the GhTUA9 gene may play an important role in fibre elongation...
Nearly identical paralogs: implications for maize (Zea mays L.) genome evolutionScott J Emrich
Interdepartmental Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, Iowa 50011, USA
Genetics 175:429-39. 2007..quot; As such, NIPs may have played important roles during the evolution and domestication of maize and may contribute to the success of long-term selection experiments in this important crop species...
Impaired innate immunity of ocular surface is the key bridge between extended contact lens wearing and occurrence of Acanthamoeba keratitisLi Li
Beijing Institute of Ophthalmology, Beijing Tongren Ophthalmic Center, Capital University of Medical Sciences, 17 Hou Gou Lane, Chong Nei Street, Beijing 100005, PR China
Med Hypotheses 70:260-4. 2008..Understanding the immunological mechanism of extended contact lens wearing on the A. keratitis may give more contributions on the research of the disease, and facilitate the production of contact lens with much higher biocompatibility...
[Inhibitory effects of RNA interference on expression of matrix metalloproteinase-9 gene and invasiveness and adhesion in ovarian cancer cells]Xiao-xia Hu
Department of Gynecology Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
Zhonghua Fu Chan Ke Za Zhi 41:579-83. 2006..2%, 35.1%, 16.0% at 90 min, respectively. CONCLUSIONS: RNAi exists in ovarian HO-8910PM cells. MMP-9 siRNA can specifically down-regulate MMP-9 expression and lead to the inhibition of invasiveness and adhesion in ovarian cancer cells...
Thalassospira xiamenensis sp. nov. and Thalassospira profundimaris sp. novChenli Liu
Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, PR China
Int J Syst Evol Microbiol 57:316-20. 2007..nov. (type strain, M-5T=DSM 17429T=CGMCC 1.3998T) and Thalassospira profundimaris sp. nov. (type strain, WP0211T=DSM 17430T=CGMCC 1.3997T) are proposed...
[Inhibitory effects of antisense MMP-9 oligodeoxynucleotides on invasiveness and adherence of ovarian cancer cells]Xiao-xia Hu
Department of Gynecological Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
Zhonghua Zhong Liu Za Zhi 28:662-5. 2006..MMP-9 may play an important role in invasion and metastasis of ovarian cells and potentially be a molecular target of blocking invasion and metastasis of ovarian cancer...
Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cellsJacqueline M Kraveka
Division of Hematology Oncology, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Biol Chem 282:16718-28. 2007..Tautomycin was also able to block the hypophosphorylation of the retinoblastoma protein observed upon fenretinide treatment. These findings suggest a novel biological function for dihydroceramides...
[SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine]Jian-chen Fang
Department of Pathology the Third Hospital, Sun Yat-sen University, Guangzhou 510630, China
Zhonghua Xue Ye Xue Za Zhi 27:670-4. 2006..CONCLUSION: DNA promoter hypermethylation is associated with SHP-1 gene silence in Daudi lymphoma cell line. 5-Aza-CdR could effectively cause demethylation and inhibit the growth of tumor cell by reactivating the gene transcription...
Assembly of beta-cyclodextrin with 3S-tetrahydro-beta-carboline-3-carboxylic acid and self-assembly of 6-(3'S-carboline-3'-carboxylaminoethylamino)-6-deoxy-beta-cyclodextrin: approaches to enhance anti-oxidation stability and anti-thrombotic potencyLi Li
College of Pharmaceutical Sciences, Capital Medical Univesity, Beijing 100069, PR China
J Phys Chem B 112:12139-47. 2008..The significant improvement of the bioactivity and stability of THCA indicates that inclusion complexation and conjugation with beta-CD provide promising approaches to improve the practical use of THCA in clinical applications...
Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2Kyriacos N Felekkis
Department of Biological Sciences, University of Cyprus, Cyprus
BMC Nephrol 9:10. 2008....
Carotenoid metabolism: biosynthesis, regulation, and beyondShan Lu
State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China
J Integr Plant Biol 50:778-85. 2008....
Modulation of brassinosteroid-regulated gene expression by Jumonji domain-containing proteins ELF6 and REF6 in ArabidopsisXiaofei Yu
Department of Genetics, Development and Cell Biology, Plant Science Institute, Iowa State University, Ames, IA 50011, USA
Proc Natl Acad Sci U S A 105:7618-23. 2008..Thus, our study establishes an important mechanism by which Jmj domain proteins modulate specific gene expression by interacting with pathway-specific transcription factors such as BES1...
Mapping a novel locus for familial atrial fibrillation on chromosome 10p11-q21Paul G A Volders
Department of Cardiology, Academic Hospital Maastricht, Maastricht, The Netherlands
Heart Rhythm 4:469-75. 2007..2 million Americans. Recently, several chromosomal loci and genes have been found to be associated with familial AF. However, in most other AF cases, the genetic basis is still poorly understood...
Molecular cloning and characterization of a new cDNA encoding hyoscyamine 6beta-hydroxylase from roots of Anisodus acutangulusGuoyin Kai
Laboratory of Plant Biotechnology, College of Life and Environment Sciences, Shanghai Normal University, Shanghai 200234, People s Republic of China
J Biochem Mol Biol 40:715-22. 2007....
[The mouse ovarian surface epithelium cells (MOSE) transformation induced by c-myc/K-ras in]De Sheng Yao
Department of Gynecological Oncology, Affiliated Cancer Hospital of Guangxi Medical University, Nanning 530021, China
Zhonghua Zhong Liu Za Zhi 28:881-5. 2006..To study the function of c-myc and K-ras in tumorigenesis of ovarian cancer...
[Expression of mineralocorticoid receptor and 11-beta-hydroxysteroid dehydrogenase type 2 in human atria during chronic atrial fibrillation: study of 25 cases]De an Pei
Department of Cardiothoracic Surgery, Changhai Hospital, Secondary Military Medical University, Shanghai 200433, China
Zhonghua Yi Xue Za Zhi 87:816-9. 2007....
Transmission of Rice stripe virus acquired from frozen infected leaves by the small brown planthopper (Laodelphax striatellus Fallen)Shixian Zhang
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agriculture Sciences, No 2 West Yuanmingyuan Road, Beijing 100094, China
J Virol Methods 146:359-62. 2007..67%) became infected, compared to 7 of 30 plants (23.33%) became infected when a single insect fed on fresh infected leaves. All rice plants expressing stripe symptoms were identified with the virus by RT-PCR...
Gene discovery and annotation using LCM-454 transcriptome sequencingScott J Emrich
Bioinformatics and Computational Biology Graduate Program, Iowa State University, Ames, IA 50010, USA
Genome Res 17:69-73. 2007..We conclude that the coupling of LCM and 454 sequencing technologies facilitates the discovery of rare, possibly cell-type-specific transcripts...
Polyphenolic profiles and antioxidant activities of heartnut (Juglans ailanthifolia Var. cordiformis) and Persian walnut (Juglans regia L.)Li Li
Department of Chemistry, Changchun Normal College, Changchun 130032, China
J Agric Food Chem 54:8033-40. 2006..These components were found to contribute to the strong total antioxidant activities measured using ferric reducing antioxidant power and photochemiluminescence methods...
Identification of an alternatively processed nicotinic receptor alpha7 subunit RNA in mouse brainPhilip A Saragoza
Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109 0930, USA
Brain Res Mol Brain Res 117:15-26. 2003..The variant alpha7 subunit was also found to act as a dominant-negative effecter of normal alpha7 subunit function...
Induction of apoptosis in mesothelioma cells by antisurvivin oligonucleotidesChunyao Xia
Department of Surgery, Comprehensive Cancer Center, University of California, San Francisco, California 94115, USA
Mol Cancer Ther 1:687-94. 2002..Down-regulation of survivin by a targeted antisense oligonucleotide appears to be an effective gene therapy approach to the treatment of mesothelioma...
Reconstitution of CD40 and CD80 in dendritic cells generated from blasts of patients with acute myeloid leukemiaLi Li
Third Department of Internal Medicine, University of Ulm, Ulm, Germany
Cancer Immun 3:8. 2003..AML-DCs express at least one LAA and strongly express HLA and costimulatory molecules, the prerequisites for eliciting T cell responses. AML-DCs may play a role in vaccine-based immunotherapies for AML patients...
Protein tyrosine nitration in the mitochondria from diabetic mouse heart. Implications to dysfunctional mitochondria in diabetesIllarion V Turko
Department of Integrative Biology and Pharmacology, Univeristy of Texas Medical School, Houston, 77030, USA
J Biol Chem 278:33972-7. 2003....
[A study of susceptibility genes mapping for aberrant B1 cell proliferation in New Zealand mice]Wei guo Xiao
Department of Hematology, The First Affiliated Hospital, China Medical University, Shenyang 110001, China
Zhonghua Nei Ke Za Zhi 42:38-40. 2003..To map the susceptibility genes for aberrant B1 cell proliferation in New Zealand mice...
[Screening and cloning gene of hepatocyte protein interacting with hepatitis C virus core protein]Ke Li
Gene Theraphy Research Center, Institute of Infectious Diseases, The 302nd Hospital of PLA, Beijing 100039, China
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 16:351-3. 2002..To clone the unknown gene of hepatocyte protein interacting with hepatitis C virus core protein...
[Cloning and sequencing of fragments associated with cytoplasm male sterility of rice]Jian bo Yang
Key Lab of Rice Genetics and Breeding, Ministry of Agriculture, Anhui Academy of Agricultural Sciences, Hefei 230031, China
Yi Chuan Xue Bao 29:808-13. 2002..The similarity ratios were 97% and 100%. It was inferred that the possible position of PWH-17 in rice (wild abortive) could be located between tRNA-Asp and Cox II, which will be discussed further...
Human SM22 alpha BAC encompasses regulatory sequences for expression in vascular and visceral smooth muscles at fetal and adult stagesRui Xu
Department of Internal Medicine, Wayne State University, Detroit, Michigan 48201, USA
Am J Physiol Heart Circ Physiol 284:H1398-407. 2003....
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational dataAmit Bahl
Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
Nucleic Acids Res 31:212-5. 2003..The software used to develop PlasmoDB has been used to create a second Apicomplexan parasite genome database, ToxoDB (http://ToxoDB.org)...
PTEN regulation of neural development and CNS stem cellsLi Li
Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
J Cell Biochem 88:24-8. 2003..Collectively, these studies demonstrate that PTEN does much more than suppressing tumors. It is a master regulator in developing and adult brain...
Distinct response of human B cell subpopulations in recognition of an innate immune signal, CpG DNAJaeho Jung
Laboratory of Cellular Immunology, Ochsner Clinic Foundation, New Orleans, LA 70121, USA
J Immunol 169:2368-73. 2002..These results suggest that CpG DNA potentiates the B cell adaptive immune response by enhancing terminal differentiation, but does not affect the generation of memory B cells...
Pathway of oxidative folding of alpha-lactalbumin: a model for illustrating the diversity of disulfide folding pathwaysJui Yoa Chang
Research Center for Protein Chemistry, Institute of Molecular Medicine and Department of Biochemistry and Molecular Biology, The University of Texas, Houston, Texas 77030, USA
Biochemistry 41:8405-13. 2002..Our study also reveals novel aspects of the folding mechanism of alpha LA that have not been described previously...
NF-kappaB-mediated up-regulation of Bcl-X(S) and Bax contributes to cytochrome c release in cyanide-induced apoptosisYan Shou
Neurotoxicology Laboratory, Department of Medicinal Chemistry and Molecular Pharmacology, Department of Basic Medical Sciences, Purdue University, West Lafayette, IN 47907-1333, USA
J Neurochem 81:842-52. 2002..It was concluded that NF-kappaB-mediated up-regulation of Bcl-X(S) and Bax is involved in regulating cytochrome c release in cyanide-induced apoptosis...
A draft sequence of the rice genome (Oryza sativa L. ssp. indica)Jun Yu
Beijing Genomics Institute/Center of Genomics and Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China
Science 296:79-92. 2002..4% of predicted rice genes had a homolog in A. thaliana. The large proportion of rice genes with no recognizable homologs is due to a gradient in the GC content of rice coding sequences...
Cloning and expression of the gene of augmenter of liver regeneration in yeast cellsJun Cheng
Gene Therapy Research Center, Institute of Infectious Diseases, 302 Hospital of PLA, Beijing 100039, China
Hepatobiliary Pancreat Dis Int 1:87-91. 2002..To study the function of augmenter of liver regeneration (ALR) as a regulatory factor that specifically stimulates hepatic cell regeneration, we constructed yeast expressive vector of ALR and expressed it in yeast cells...
Alternative promoters and polyadenylation regulate tissue-specific expression of Hemogen isoforms during hematopoiesis and spermatogenesisLi V Yang
Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan, USA
Dev Dyn 228:606-16. 2003..Finally, fluorescence in situ hybridization demonstrates that HEMGN is localized to chromosome 4 A5-B2 in mouse and to chromosome 9q22 in human, which is a region known to harbor a cluster of leukemia breakpoints...
Uveal melanocytes do not respond to or express receptors for alpha-melanocyte-stimulating hormoneLi Li
Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0592, USA
Invest Ophthalmol Vis Sci 47:4507-12. 2006..CONCLUSIONS: In conclusion, ocular pigmentation does not appear to be regulated by melanocyte stimulating hormone...
A brassinolide-suppressed rice MADS-box transcription factor, OsMDP1, has a negative regulatory role in BR signalingKe Duan
Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, 20 Nanxincun Road, 100093 Beijing, China
Plant J 47:519-31. 2006....
Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fatesLi Li
Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot 76100, Israel
Development 131:5277-86. 2004....
Enhanced cell survival of Hep3B cells by the hepatitis B x antigen effector, URG11, is associated with upregulation of beta-cateninZhaorui Lian
Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA
Hepatology 43:415-24. 2006..These observations also suggest that URG11 may be a regulatory element in the beta-catenin signaling pathway and may be a target for chemoprevention of HCC...
Functional analysis of a reproductive organ predominant expressing promoter in cotton plantsMaozhi Ren
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Sci China C Life Sci 48:452-9. 2005..The results showed that the arf1 promoter was a typical reproductive organ-specific promoter. Hopefully, the arf1 promoter can be a regulatory element for designing cotton reproductive organs with desired characteristics...
Brassinosteroids stimulate plant tropisms through modulation of polar auxin transport in Brassica and ArabidopsisLi Li
National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032 Shanghai, China
Plant Cell 17:2738-53. 2005....
Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cellsYanhong Gao
Laboratory of Stem Cell Biology, Beijing Institute of Transfusion Medicine, 27 Taiping Road, Beijing 100850, PR China
Biochem Biophys Res Commun 335:343-50. 2005..Furthermore, overexpressed spindlin1 cells formed colonies in soft agar in vitro and formed tumors in nude mice. Our findings provide direct evidence that spindlin1 gene may contribute to tumorigenesis...
[Study on the expression and mutation of cadherin 6 gene in human ovarian carcinoma]Dan-Rong Li
Department of Basic Science, Cancer Institute of Guangxi Zhuang Automomous Region, Nanning 530021, China
Zhonghua Fu Chan Ke Za Zhi 39:616-9. 2004..It may be a prognostic marker of ovarian carcinoma...
[Reversal of multidrug resistance of MCF-7/ADR in nude mice by grape seed polyphenol]Cui-juan Zhang
Department of Pathology, Medical School of Shandong University, Jinan 250012, China
Zhonghua Wai Ke Za Zhi 42:795-8. 2004..07% +/- 0.43%), P < 0.05. CONCLUSION: GSP can effectively reversed the resistance of MCF-7/ADR cells in nude mice, the mechanism may be correlated with inhibition of Pgp expression and apoptosis...
Comparative mapping of a major aluminum tolerance gene in sorghum and other species in the poaceaeJurandir V Magalhaes
U. S. Plant Soil and Nutrition Laboratory, U. S. Department of Agriculture-Agricultural Research Service, Cornell University, Ithaca, New York 14853, USA
Genetics 167:1905-14. 2004..Therefore, this study demonstrates a clear evolutionary link between genes and QTL encoding the same trait in distantly related species within a single plant family...
Development and characterization of five cell models for chemoresistance studies of human ovarian carcinomaLi Li
Department of Gynecologic Oncology, Medical University of Guangxi Cancer Institute and Hospital, Nanning 530021, P R China
Int J Mol Med 14:257-64. 2004..Taken together, our findings indicate that these models may be potentially used to assess the biochemical and genetic mechanisms of drug resistance in human ovarian cancer and to identify new drug resistance-related genes...
Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolismLi Li
Immunology Group, Institute of Cell and Molecular Sciences, St Barts and The Royal London School of Medicine, 59 Bartholomew s Close, London EC1A 7ED, United Kingdom
J Biol Chem 279:34107-14. 2004..Therefore, our results indicate that SOCS-6 may provide a dynamically regulated mechanism by which insulin can transiently overcome the negative effects that p85 monomers have on signaling via PI 3-kinase-dependent signaling pathways...
Differential expression of thromboxane synthase in prostate carcinoma: role in tumor cell motilityDaotai Nie
Department of Radiation Oncology, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, Michigan 48202, USA
Am J Pathol 164:429-39. 2004..Finally, increased expression of TxS in DU145 cells increased cell motility. Our data suggest that human PCa cells express TxS and that this enzyme may contribute to PCa progression through modulating cell motility...
[Refolding and purification of Plasmodium falciparum glutamate dehydrogenase fusion protein]Yan Li
Institute of Tropical Medicine, First Military Medical University, Guangzhou 510515, China
Di Yi Jun Yi Da Xue Xue Bao 23:1273-6. 2003..CONCLUSION: The high-purity and biologically active GDH/GST can be acquired by dilution renaturation followed by two-step ion exchange chromatography...
Activation of K(+) channels and increased migration of differentiated intestinal epithelial cells after woundingJaladanki N Rao
Department of Surgery, University of Maryland School of Medicine, 10 North Greene Street, Baltimore, MD 21201, USA
Am J Physiol Cell Physiol 282:C885-98. 2002..These results suggest that increased migration of differentiated intestinal epithelial cells is mediated, at least partially, by increasing Kv channel activity and Ca(2+) influx during restitution...
