Research Topics
| Eric C LedbetterSummaryAffiliation: Cornell University Country: USA Publications
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Publications
Frequency of spontaneous canine herpesvirus-1 reactivation and ocular viral shedding in latently infected dogs and canine herpesvirus-1 reactivation and ocular viral shedding induced by topical administration of cyclosporine and systemic administration ofEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 73:1079-84. 2012..To determine the frequency of spontaneous canine herpesvirus-1 (CHV-1) reactivation and ocular viral shedding in latently infected dogs and the effect of topical ocular administration of cyclosporine...
In vivo confocal microscopy of equine fungal keratitisEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Ophthalmol 14:1-9. 2011....
The effect of topical ocular corticosteroid administration in dogs with experimentally induced latent canine herpesvirus-1 infectionEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Exp Eye Res 90:711-7. 2010..The crystalline keratopathy may have resulted from corneal degeneration associated with metaherpetic disease, corticosteroid administration, or a combination of both factors...
In vivo confocal microscopy of the normal equine cornea and limbusEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Ophthalmol 12:57-64. 2009..To describe morphologic features, pachymetry and endothelial cell density of the normal equine cornea and limbus by in vivo confocal microscopy...
Microbial contamination of the anterior chamber during cataract phacoemulsification and intraocular lens implantation in dogsEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
Vet Ophthalmol 7:327-34. 2004..This contamination is independent of the patient and surgical variables investigated...
Outbreak of ocular disease associated with naturally-acquired canine herpesvirus-1 infection in a closed domestic dog colonyEric C Ledbetter
Department of Clinical Sciences, Ithaca, NY 14853, USA
Vet Ophthalmol 12:242-7. 2009..To describe clinical and virological findings of an outbreak of ocular disease attributed to naturally-acquired primary canine herpesvirus-1 (CHV-1) infection in a closed domestic dog colony...
Brucella canis endophthalmitis in 3 dogs: clinical features, diagnosis, and treatmentEric C Ledbetter
Cornell University, College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY 14853, USA
Vet Ophthalmol 12:183-91. 2009..To describe historical, clinical and diagnostic features of dogs with Brucella canis endophthalmitis and the response to medical therapy...
Experimental reactivation of latent canine herpesvirus-1 and induction of recurrent ocular disease in adult dogsEric C Ledbetter
Cornell University, College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY 14853, United States
Vet Microbiol 138:98-105. 2009..005), or viral shedding. Administration of an immunosuppressive dosage of systemic prednisolone to adult dogs latently infected with CHV-1 may result in viral reactivation and ocular disease recrudescence...
Pathogenic phenotype and genotype of Pseudomonas aeruginosa isolates from spontaneous canine ocular infectionsEric C Ledbetter
College of Veterinary Medicine, Department of Clinical Sciences, Cornell University, Ithaca, New York 14853 6414, USA
Invest Ophthalmol Vis Sci 50:729-36. 2009..aeruginosa ocular infection...
Isolation of obligate anaerobic bacteria from ulcerative keratitis in domestic animalsEric C Ledbetter
Department of Clinical Sciences, and College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Ophthalmol 11:114-22. 2008....
Efficacy of two chondroitin sulfate ophthalmic solutions in the therapy of spontaneous chronic corneal epithelial defects and ulcerative keratitis associated with bullous keratopathy in dogsEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
Vet Ophthalmol 9:77-87. 2006..To determine the efficacy of two antimicrobial-chondroitin sulfate ophthalmic solutions in the therapy of spontaneous chronic corneal epithelial defects (SCCED) and ulcerative keratitis associated with bullous keratopathy in dogs...
Experimental primary ocular canine herpesvirus-1 infection in adult dogsEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 70:513-21. 2009..Features of this infection resembled herpes simplex virus primary ocular infection in humans...
In vitro fluoroquinolone susceptibility of Pseudomonas aeruginosa isolates from dogs with ulcerative keratitisEric C Ledbetter
Departments of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 68:638-42. 2007..To determine the in vitro fluoroquinolone susceptibility profiles of Pseudomonas aeruginosa isolates from dogs with ulcerative keratitis. Animals-27 dogs with P. aeruginosa-associated ulcerative keratitis...
Canine reproductive, respiratory, and ocular diseases due to canine herpesvirusJames F Evermann
Department of Veterinary Clinical Sciences and Washington Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA
Vet Clin North Am Small Anim Pract 41:1097-120. 2011..Recognition of the various forms of CHV-induced disease, availability of diagnostic assays with increased sensitivity, and the formation of reliable biosecurity measures will allow for better control steps...
Isolation and characterization of two bacteriophages with strong in vitro antimicrobial activity against Pseudomonas aeruginosa isolated from dogs with ocular infectionsThiago M A Santos
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Am J Vet Res 72:1079-86. 2011..To isolate and characterize bacteriophages with strong in vitro lytic activity against various pathogenic Pseudomonas aeruginosa strains isolated from dogs with ocular infections...
Virologic survey of dogs with naturally acquired idiopathic conjunctivitisEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Am Vet Med Assoc 235:954-9. 2009....
Acute primary canine herpesvirus-1 dendritic ulcerative keratitis in an adult dogKristen J Gervais
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA
Vet Ophthalmol 15:133-8. 2012..In conjunction with previous studies, this case report supports a central role for alterations in host immune status in the pathogenesis and clinical manifestations of CHV-1 ocular disease in dogs...
Corneal ulceration associated with naturally occurring canine herpesvirus-1 infection in two adult dogsEric C Ledbetter
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Am Vet Med Assoc 229:376-84. 2006..The viruses isolated were identified as CHV-1, and the morphology, antigenicity, and genotype were similar to those for CHV-1 isolates obtained from a puppy that died from systemic CHV-1 infection...
In vitro susceptibility patterns of fungi associated with keratomycosis in horses of the northeastern United States: 68 cases (1987-2006)Eric C Ledbetter
Department of Clinical Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA
J Am Vet Med Assoc 231:1086-91. 2007..To determine in vitro susceptibility patterns of fungi associated with keratomycosis in horses in the northeastern United States and compare those patterns with results of studies from other geographic regions...
Orbital abscess bacterial isolates and in vitro antimicrobial susceptibility patterns in dogs and catsAnnie L Wang
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Ophthalmol 12:91-6. 2009..To determine bacterial populations, in vitro antimicrobial susceptibility patterns, and sources of microorganisms for dogs and cats with orbital abscess...
Central diabetes insipidus in an African Grey parrotSimon R Starkey
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
J Am Vet Med Assoc 237:415-9. 2010..A 5.5-year-old sexually intact female African Grey parrot (Psittacus erithacus) was evaluated for a 1-year history of pronounced polyuria and polydipsia. The bird also had a 1-month history of signs of mild depression and mydriasis...
Effect of short-term diphenhydramine administration on aqueous tear production in normal dogsKeith W Montgomery
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Ophthalmol 14:395-9. 2011..To perform a randomized, placebo-controlled, masked clinical trial using a cross-over design to determine the effect of oral diphenhydramine on aqueous tear production in normal dogs...
Periocular cutaneous mast cell tumors in cats: evaluation of surgical excision (33 cases)Keith W Montgomery
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Vet Ophthalmol 13:26-30. 2010..To describe feline periocular cutaneous mast cell tumor (CMCT) clinical features, rates of local tumor recurrence and metastases, and cat survival time following surgical excision...
Effects of cyclophosphamide myelosuppression in adult dogs with latent canine herpesvirus-1 infectionPatricia Mundy
Cornell University, College of Veterinary Medicine, Department of Clinical Sciences, Ithaca, NY 14853, USA
Vet Microbiol 159:230-5. 2012..Myelosuppression elicited by a single dose of cyclophosphamide does not result in detectable recurrent ocular CHV-1 infection in adult dogs with experimentally induced latent CHV-1 infection...
