Karin Hoelzer

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. doi request reprint Listeria monocytogenes growth dynamics on produce: a review of the available data for predictive modeling
    Karin Hoelzer
    Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, Maryland 20740, USA
    Foodborne Pathog Dis 9:661-73. 2012
  2. pmc Animal models of listeriosis: a comparative review of the current state of the art and lessons learned
    Karin Hoelzer
    U, S, Food and Drug Administration, Center for Food Safety and Applied Nutrition, 5100 Paint Branch Parkway, College Park, MD 20707, USA
    Vet Res 43:18. 2012
  3. doi request reprint Virus inactivation on hard surfaces or in suspension by chemical disinfectants: systematic review and meta-analysis of norovirus surrogates
    K Hoelzer
    US Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, Maryland 20740, USA
    J Food Prot 76:1006-16. 2013
  4. doi request reprint Produce consumption in the United States: an analysis of consumption frequencies, serving sizes, processing forms, and high-consuming population subgroups for microbial risk assessments
    K Hoelzer
    Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, MD 20740, USA
    J Food Prot 75:328-40. 2012
  5. doi request reprint Estimation of Listeria monocytogenes transfer coefficients and efficacy of bacterial removal through cleaning and sanitation
    Karin Hoelzer
    US Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD 20740, United States
    Int J Food Microbiol 157:267-77. 2012
  6. pmc Agar disk diffusion and automated microbroth dilution produce similar antimicrobial susceptibility testing results for Salmonella serotypes Newport, Typhimurium, and 4,5,12:i-, but differ in economic cost
    Karin Hoelzer
    Department of Food Science, Cornell University, Ithaca, New York 14850, USA
    Foodborne Pathog Dis 8:1281-8. 2011
  7. doi request reprint Structured expert elicitation about Listeria monocytogenes cross-contamination in the environment of retail deli operations in the United States
    Karin Hoelzer
    Department of Food Science, Cornell University, 410 Stocking Hall, Ithaca, NY 14850, USA
    Risk Anal 32:1139-56. 2012
  8. pmc Salmonella Cerro isolated over the past twenty years from various sources in the US represent a single predominant pulsed-field gel electrophoresis type
    K Hoelzer
    Department of Food Science, Cornell University, Ithaca, NY 14850, USA
    Vet Microbiol 150:389-93. 2011
  9. pmc Animal contact as a source of human non-typhoidal salmonellosis
    Karin Hoelzer
    Department of Food Science, 410 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Vet Res 42:34. 2011
  10. pmc The prevalence of multidrug resistance is higher among bovine than human Salmonella enterica serotype Newport, Typhimurium, and 4,5,12:i:- isolates in the United States but differs by serotype and geographic region
    K Hoelzer
    Department of Food Science, Cornell University, 410 Stocking Hall, Ithaca, NY 14850, USA
    Appl Environ Microbiol 76:5947-59. 2010

Collaborators

Detail Information

Publications26

  1. doi request reprint Listeria monocytogenes growth dynamics on produce: a review of the available data for predictive modeling
    Karin Hoelzer
    Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, Maryland 20740, USA
    Foodborne Pathog Dis 9:661-73. 2012
    ..monocytogenes population density, and possibly in the impact of post-harvest processing, but data are currently insufficient to predict growth behavior, and the listeriosis risk appears to be also governed by additional factors...
  2. pmc Animal models of listeriosis: a comparative review of the current state of the art and lessons learned
    Karin Hoelzer
    U, S, Food and Drug Administration, Center for Food Safety and Applied Nutrition, 5100 Paint Branch Parkway, College Park, MD 20707, USA
    Vet Res 43:18. 2012
    ..We deliberately chose a historical, comparative and cross-disciplinary approach, striving to reveal clues that may help predict the ultimate value of each animal model in spite of incomplete data...
  3. doi request reprint Virus inactivation on hard surfaces or in suspension by chemical disinfectants: systematic review and meta-analysis of norovirus surrogates
    K Hoelzer
    US Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, Maryland 20740, USA
    J Food Prot 76:1006-16. 2013
    ..Therefore, extrapolation of results between surrogates or from surrogates to human NoV must consider the type of disinfectant studied...
  4. doi request reprint Produce consumption in the United States: an analysis of consumption frequencies, serving sizes, processing forms, and high-consuming population subgroups for microbial risk assessments
    K Hoelzer
    Center for Food Safety and Applied Nutrition, U S Food and Drug Administration, College Park, MD 20740, USA
    J Food Prot 75:328-40. 2012
    ..These results are valuable for risk assessments and outbreak investigations and allow targeting of risk communication or interventions to those individuals at greatest risk...
  5. doi request reprint Estimation of Listeria monocytogenes transfer coefficients and efficacy of bacterial removal through cleaning and sanitation
    Karin Hoelzer
    US Food and Drug Administration, Center for Food Safety and Applied Nutrition, College Park, MD 20740, United States
    Int J Food Microbiol 157:267-77. 2012
    ..monocytogenes cross-contamination dynamics in environments where foods are handled, and to assess the potential impact of different intervention strategies...
  6. pmc Agar disk diffusion and automated microbroth dilution produce similar antimicrobial susceptibility testing results for Salmonella serotypes Newport, Typhimurium, and 4,5,12:i-, but differ in economic cost
    Karin Hoelzer
    Department of Food Science, Cornell University, Ithaca, New York 14850, USA
    Foodborne Pathog Dis 8:1281-8. 2011
    ..Economic feasibility clearly depends on the specific laboratory settings, and disk diffusion might be an attractive alternative for certain applications such as surveillance studies...
  7. doi request reprint Structured expert elicitation about Listeria monocytogenes cross-contamination in the environment of retail deli operations in the United States
    Karin Hoelzer
    Department of Food Science, Cornell University, 410 Stocking Hall, Ithaca, NY 14850, USA
    Risk Anal 32:1139-56. 2012
    ..Overall, our study demonstrates the value and caveats of expert elicitation to identify data gaps and prioritize research efforts...
  8. pmc Salmonella Cerro isolated over the past twenty years from various sources in the US represent a single predominant pulsed-field gel electrophoresis type
    K Hoelzer
    Department of Food Science, Cornell University, Ithaca, NY 14850, USA
    Vet Microbiol 150:389-93. 2011
    ....
  9. pmc Animal contact as a source of human non-typhoidal salmonellosis
    Karin Hoelzer
    Department of Food Science, 410 Stocking Hall, Cornell University, Ithaca, NY 14853, USA
    Vet Res 42:34. 2011
    ....
  10. pmc The prevalence of multidrug resistance is higher among bovine than human Salmonella enterica serotype Newport, Typhimurium, and 4,5,12:i:- isolates in the United States but differs by serotype and geographic region
    K Hoelzer
    Department of Food Science, Cornell University, 410 Stocking Hall, Ithaca, NY 14850, USA
    Appl Environ Microbiol 76:5947-59. 2010
    ..In addition, the study provides evidence for the value of including antimicrobial resistance data in epidemiological investigations and highlights the benefits and potential problems of combining subtyping methods...
  11. pmc Phylogenetic analysis reveals the emergence, evolution and dispersal of carnivore parvoviruses
    Karin Hoelzer
    Baker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Gen Virol 89:2280-9. 2008
    ..Such limited viral migration contrasts with the global spread of the virus observed during the early phase of the CPV pandemic, but corresponds to the more endemic nature of current CPV infections...
  12. pmc Identification and characterization of novel Salmonella mobile elements involved in the dissemination of genes linked to virulence and transmission
    Andrea I Moreno Switt
    Department of Food Science, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 7:e41247. 2012
    ..The abundance of mobile elements encoding pathogenic properties may facilitate the emergence of strains with novel combinations of pathogenic traits...
  13. pmc Intrahost evolutionary dynamics of canine influenza virus in naive and partially immune dogs
    Karin Hoelzer
    Baker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Hungerford Hill Road, Ithaca, NY 14853, USA
    J Virol 84:5329-35. 2010
    ..Potentially advantageous mutations arise readily during the course of single infections and may give rise to antigenic escape or host range variants...
  14. pmc Within-host genetic diversity of endemic and emerging parvoviruses of dogs and cats
    Karin Hoelzer
    Baker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Virol 82:11096-105. 2008
    ..These included residues with evidence of positive selection at the population level, which is compatible with a role of this protein in host adaptation...
  15. pmc Salmonella bacteriophage diversity reflects host diversity on dairy farms
    Andrea I Moreno Switt
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    Food Microbiol 36:275-85. 2013
    ....
  16. doi request reprint New data, strategies, and insights for Listeria monocytogenes dose-response models: summary of an interagency workshop, 2011
    K Hoelzer
    Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, MD, USA
    Risk Anal 33:1568-81. 2013
    ..monocytogenes dose-response. This article also discusses new insights on dose-response modeling for L. monocytogenes and research opportunities to meet future needs. ..
  17. pmc A whole-genome single nucleotide polymorphism-based approach to trace and identify outbreaks linked to a common Salmonella enterica subsp. enterica serovar Montevideo pulsed-field gel electrophoresis type
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    Appl Environ Microbiol 77:8648-55. 2011
    ..This study demonstrates that next-generation-based SNP typing provides the resolution and accuracy needed for outbreak investigations of food-borne pathogens that cannot be distinguished by currently used subtyping methods...
  18. pmc The emergence of parvoviruses of carnivores
    Karin Hoelzer
    Department of Microbiology and Immunology, Cornell University, Ithaca, NY, USA
    Vet Res 41:39. 2010
    ..CPV represents a valuable model for understanding disease emergence through cross-species transmission, while MEV provides an interesting comparison...
  19. doi request reprint Prevalence, distribution, and diversity of Listeria monocytogenes in retail environments, focusing on small establishments and establishments with a history of failed inspections
    Karin Hoelzer
    Department of Food Science, Cornell University, Ithaca, New York 14853, USA
    J Food Prot 74:1083-95. 2011
    ..Isolates belonging to the same ribotype were often found dispersed across multiple sites within an operation...
  20. pmc Cytoplasmic targeting motifs control localization of toll-like receptor 9
    Cynthia A Leifer
    Cornell University College of Veterinary Medicine, Ithaca, New York 14853, USA
    J Biol Chem 281:35585-92. 2006
    ..We propose a model whereby modification of the cytoplasmic tail of TLR9 results in trafficking to early endosomes where it encounters CpG DNA...
  21. pmc Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica
    Henk C den Bakker
    Department of Food Science, Cornell University, Ithaca, NY 14853, USA
    BMC Genomics 12:425. 2011
    ..Here we used a comparative genomics approach to define the population structure of Salmonella enterica subsp. enterica, and identify clade-specific genes that may be the result of ecological specialization...
  22. pmc Detecting small changes and additional peptides in the canine parvovirus capsid structure
    Christian D S Nelson
    Department of Microbiology and Immunology, Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Virol 82:10397-407. 2008
    ..Exposure of viral DNA to the external environment started above 50 degrees C. Some negative stains showed increased permeability of empty capsids at higher temperatures, but no effects were seen after EGTA treatment...
  23. pmc Evaluation of a vectored equine herpesvirus type 1 (EHV-1) vaccine expressing H3 haemagglutinin in the protection of dogs against canine influenza
    Cristina Rosas
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Vaccine 26:2335-43. 2008
    ..We concluded that the EHV-1/H3 recombinant vector can be a valuable alternative for protection of dogs against clinical disease induced by CIV and can significantly reduce virus spread...
  24. pmc Presence and role of cytosine methylation in DNA viruses of animals
    Karin Hoelzer
    Baker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Nucleic Acids Res 36:2825-37. 2008
    ..Here we briefly introduce cytosine methylation before reviewing what is currently known about CpG methylation in DNA viruses...
  25. doi request reprint Assessment of the risk of salmonellosis from internally contaminated shell eggs following initial storage at 18 °C (65 °F), compared with 7 °C (45 °F)
    R Pouillot
    U S Food and Drug Administration, Center for Food Safety and Applied Nutrition, USA Electronic address
    Food Microbiol 43:16-9. 2014
    ..The predicted risk of salmonellosis from the consumption of eggs held and transported at 18.3 °C and subsequently diverted to human consumption is 25 times higher than the risk when eggs are held and transported at 7.2 °C. ..
  26. pmc Comparative analysis reveals frequent recombination in the parvoviruses
    Laura A Shackelton
    Center for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, Mueller Laboratory, University Park, PA 16802, USA
    J Gen Virol 88:3294-301. 2007
    ..Further, the rodent parvoviruses show complex evolutionary histories for separate genomic regions, suggesting recombination at the interspecies level...