Brian S Hamilton

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Influenza virus-mediated membrane fusion: determinants of hemagglutinin fusogenic activity and experimental approaches for assessing virus fusion
    Brian S Hamilton
    Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA
    Viruses 4:1144-68. 2012
  2. pmc Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12
    Brian S Hamilton
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Biol Chem 288:17399-407. 2013
  3. pmc Acquisition of a novel eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site confers intracellular cleavage of an H7N7 influenza virus hemagglutinin
    Brian S Hamilton
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Virology 434:88-95. 2012
  4. pmc Mutation in spike protein cleavage site and pathogenesis of feline coronavirus
    Beth N Licitra
    Cornell University College of Veterinary Medicine, Ithaca, New York 14853, USA
    Emerg Infect Dis 19:1066-73. 2013
  5. pmc Cleavage activation of the human-adapted influenza virus subtypes by matriptase reveals both subtype and strain specificities
    Brian S Hamilton
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    J Virol 86:10579-86. 2012

Collaborators

  • Beth N Licitra
  • Jean K Millet
  • Vera D Rinaldi
  • Andrew D Regan
  • Gary R Whittaker
  • Gerald E Duhamel

Detail Information

Publications5

  1. pmc Influenza virus-mediated membrane fusion: determinants of hemagglutinin fusogenic activity and experimental approaches for assessing virus fusion
    Brian S Hamilton
    Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA
    Viruses 4:1144-68. 2012
    ....
  2. pmc Cleavage activation of human-adapted influenza virus subtypes by kallikrein-related peptidases 5 and 12
    Brian S Hamilton
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Biol Chem 288:17399-407. 2013
    ..Activation of the thrombolytic zymogens may therefore allow for both direct and indirect activation of the HA of human-adapted influenza viruses by kallikrein 5 and kallikrein 12...
  3. pmc Acquisition of a novel eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site confers intracellular cleavage of an H7N7 influenza virus hemagglutinin
    Brian S Hamilton
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Virology 434:88-95. 2012
    ..Our studies show that acquisition of the eleven amino acid insertion offers an alternative mechanism for intracellular cleavage of influenza HA...
  4. pmc Mutation in spike protein cleavage site and pathogenesis of feline coronavirus
    Beth N Licitra
    Cornell University College of Veterinary Medicine, Ithaca, New York 14853, USA
    Emerg Infect Dis 19:1066-73. 2013
    ..We document a functionally relevant S1/S2 mutation that arises when FIP develops in a cat. These insights into FIP pathogenesis may be useful in development of diagnostic, prevention, and treatment measures against coronaviruses...
  5. pmc Cleavage activation of the human-adapted influenza virus subtypes by matriptase reveals both subtype and strain specificities
    Brian S Hamilton
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    J Virol 86:10579-86. 2012
    ..Our data demonstrate that matriptase has the ability to cleave HA directly or indirectly by activating HA-cleaving zymogens...