Research Topics
Species | John EwerSummaryAffiliation: Cornell University Country: USA Publications
Research Grants
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Detail Information
Publications
Neuroendocrine control of larval ecdysis behavior in Drosophila: complex regulation by partially redundant neuropeptidesAnthony C Clark
Cornell University, Entomology Department, Ithaca, New York 14853, USA
J Neurosci 24:4283-92. 2004..We propose that important additional neuropeptides, and additional interactions between known regulators, contribute to the mechanisms underlying insect ecdysis behaviors...- Targeted ablation of CCAP neuropeptide-containing neurons of Drosophila causes specific defects in execution and circadian timing of ecdysis behaviorJae H Park
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, USA
Development 130:2645-56. 2003..Nevertheless, an unexpected finding of this work is that the primary functions of CCAP as well as its importance in the control of ecdysis behaviors may change during the postembryonic development of Drosophila... - Behavioral endocrinology: lighting up peptidergic neurons that mediate a complex behaviorJohn Ewer
Cornell University, Department of Entomology, 5130 Comstock Hall, Ithaca, New York 14853, USA
Curr Biol 16:R682-4. 2006.... 
How the ecdysozoan changed its coatJohn Ewer
Entomology Department, Cornell University, Ithaca, New York, USA
PLoS Biol 3:e349. 2005- Behavioral actions of neuropeptides in invertebrates: insights from DrosophilaJohn Ewer
Entomology Department, Cornell University, 5130 Comstock Hall, Ithaca, NY 14853, USA
Horm Behav 48:418-29. 2005..In addition, I discuss more generally approaches that are available in this organism, which make it especially useful for investigating the hormonal control of behavior... 
Genetic analysis of ecdysis behavior in Drosophila reveals partially overlapping functions of two unrelated neuropeptidesEleanor C Lahr
Department of Entomology, Cornell University, Ithaca, New York 14853, USA
J Neurosci 32:6819-29. 2012..These findings have important implications for understanding the regulation of this vital insect behavior and the mechanisms by which hormones and neuropeptides control the physiology and behavior of animals...- Construction and characterization of deletions with defined end points in Drosophila using P elements in transAdam C Paré
Entomology Department, Cornell University, Ithaca, New York 14853, USA
Genetics 181:53-63. 2009..Importantly, it can use preexisting P-element insertion strains and does not rely on the use of transposable elements that are engineered to cause specific DNA rearrangements... - Bursicon, the tanning hormone of insects: recent advances following the discovery of its molecular identityHans Willi Honegger
Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:989-1005. 2008..melanogaster. Although much remains to be learned, the elucidation of its molecular identity and that of its receptor has provided the breakthrough needed for investigating the diverse actions of this critical insect neurohormone... - Use of targetable gfp-tagged neuropeptide for visualizing neuropeptide release following execution of a behaviorQasim M Husain
Cornell University, Entomology Department, 5130 Comstock Hall, Ithaca, New York 14850, USA
J Neurobiol 59:181-91. 2004.... - Characterization of mRNA expression in single neuronsDavid M Lin
Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA
Methods Mol Biol 399:133-52. 2007..Here we provide detailed protocols for harvesting RNA from single cells, methods for RNA purification, and PCR amplification... - Role of the neuropeptide CCAP in Drosophila cardiac functionDavide Dulcis
Division of Neurobiology, University of Arizona, 611 Gould Simpson Science Building, Tucson, Arizona 85721, USA
J Neurobiol 64:259-74. 2005..However, this reduction was not sufficient to compromise CCAP's function in ecdysis behavior and heartbeat regulation... - Identification of the gene encoding bursicon, an insect neuropeptide responsible for cuticle sclerotization and wing spreadingElizabeth M Dewey
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
Curr Biol 14:1208-13. 2004..It is the first member of the cystine knot family to have a defined function in invertebrates. Mutants show that the spectrum of bursicon actions is broader than formerly demonstrated... - Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2Ching Wei Luo
Division of Reproductive Biology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305 5317, USA
Proc Natl Acad Sci U S A 102:2820-5. 2005..Because bursicon subunit genes are homologous to the vertebrate bone morphogenetic protein antagonists, our findings also facilitate investigation on the function of these proteins during vertebrate development...
Research Grants
- Circadian control of a behavioral outputJohn Ewer; Fiscal Year: 2007..Thus it offers a unique opportunity to elucidate how the activity of the clock is coupled to the mechanism that controls a behavioral output. ..