John Ewer

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Neuroendocrine control of larval ecdysis behavior in Drosophila: complex regulation by partially redundant neuropeptides
    Anthony C Clark
    Cornell University, Entomology Department, Ithaca, New York 14853, USA
    J Neurosci 24:4283-92. 2004
  2. ncbi request reprint Targeted ablation of CCAP neuropeptide-containing neurons of Drosophila causes specific defects in execution and circadian timing of ecdysis behavior
    Jae H Park
    Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, USA
    Development 130:2645-56. 2003
  3. ncbi request reprint Behavioral endocrinology: lighting up peptidergic neurons that mediate a complex behavior
    John Ewer
    Cornell University, Department of Entomology, 5130 Comstock Hall, Ithaca, New York 14853, USA
    Curr Biol 16:R682-4. 2006
  4. pmc How the ecdysozoan changed its coat
    John Ewer
    Entomology Department, Cornell University, Ithaca, New York, USA
    PLoS Biol 3:e349. 2005
  5. ncbi request reprint Behavioral actions of neuropeptides in invertebrates: insights from Drosophila
    John Ewer
    Entomology Department, Cornell University, 5130 Comstock Hall, Ithaca, NY 14853, USA
    Horm Behav 48:418-29. 2005
  6. doi request reprint Genetic analysis of ecdysis behavior in Drosophila reveals partially overlapping functions of two unrelated neuropeptides
    Eleanor C Lahr
    Department of Entomology, Cornell University, Ithaca, New York 14853, USA
    J Neurosci 32:6819-29. 2012
  7. pmc Construction and characterization of deletions with defined end points in Drosophila using P elements in trans
    Adam C Paré
    Entomology Department, Cornell University, Ithaca, New York 14853, USA
    Genetics 181:53-63. 2009
  8. doi request reprint Bursicon, the tanning hormone of insects: recent advances following the discovery of its molecular identity
    Hans Willi Honegger
    Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:989-1005. 2008
  9. ncbi request reprint Use of targetable gfp-tagged neuropeptide for visualizing neuropeptide release following execution of a behavior
    Qasim M Husain
    Cornell University, Entomology Department, 5130 Comstock Hall, Ithaca, New York 14850, USA
    J Neurobiol 59:181-91. 2004
  10. ncbi request reprint Characterization of mRNA expression in single neurons
    David M Lin
    Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA
    Methods Mol Biol 399:133-52. 2007

Research Grants

  1. Circadian control of a behavioral output
    John Ewer; Fiscal Year: 2007

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Neuroendocrine control of larval ecdysis behavior in Drosophila: complex regulation by partially redundant neuropeptides
    Anthony C Clark
    Cornell University, Entomology Department, Ithaca, New York 14853, USA
    J Neurosci 24:4283-92. 2004
    ..We propose that important additional neuropeptides, and additional interactions between known regulators, contribute to the mechanisms underlying insect ecdysis behaviors...
  2. ncbi request reprint Targeted ablation of CCAP neuropeptide-containing neurons of Drosophila causes specific defects in execution and circadian timing of ecdysis behavior
    Jae H Park
    Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, USA
    Development 130:2645-56. 2003
    ..Nevertheless, an unexpected finding of this work is that the primary functions of CCAP as well as its importance in the control of ecdysis behaviors may change during the postembryonic development of Drosophila...
  3. ncbi request reprint Behavioral endocrinology: lighting up peptidergic neurons that mediate a complex behavior
    John Ewer
    Cornell University, Department of Entomology, 5130 Comstock Hall, Ithaca, New York 14853, USA
    Curr Biol 16:R682-4. 2006
    ....
  4. pmc How the ecdysozoan changed its coat
    John Ewer
    Entomology Department, Cornell University, Ithaca, New York, USA
    PLoS Biol 3:e349. 2005
  5. ncbi request reprint Behavioral actions of neuropeptides in invertebrates: insights from Drosophila
    John Ewer
    Entomology Department, Cornell University, 5130 Comstock Hall, Ithaca, NY 14853, USA
    Horm Behav 48:418-29. 2005
    ..In addition, I discuss more generally approaches that are available in this organism, which make it especially useful for investigating the hormonal control of behavior...
  6. doi request reprint Genetic analysis of ecdysis behavior in Drosophila reveals partially overlapping functions of two unrelated neuropeptides
    Eleanor C Lahr
    Department of Entomology, Cornell University, Ithaca, New York 14853, USA
    J Neurosci 32:6819-29. 2012
    ..These findings have important implications for understanding the regulation of this vital insect behavior and the mechanisms by which hormones and neuropeptides control the physiology and behavior of animals...
  7. pmc Construction and characterization of deletions with defined end points in Drosophila using P elements in trans
    Adam C Paré
    Entomology Department, Cornell University, Ithaca, New York 14853, USA
    Genetics 181:53-63. 2009
    ..Importantly, it can use preexisting P-element insertion strains and does not rely on the use of transposable elements that are engineered to cause specific DNA rearrangements...
  8. doi request reprint Bursicon, the tanning hormone of insects: recent advances following the discovery of its molecular identity
    Hans Willi Honegger
    Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:989-1005. 2008
    ..melanogaster. Although much remains to be learned, the elucidation of its molecular identity and that of its receptor has provided the breakthrough needed for investigating the diverse actions of this critical insect neurohormone...
  9. ncbi request reprint Use of targetable gfp-tagged neuropeptide for visualizing neuropeptide release following execution of a behavior
    Qasim M Husain
    Cornell University, Entomology Department, 5130 Comstock Hall, Ithaca, New York 14850, USA
    J Neurobiol 59:181-91. 2004
    ....
  10. ncbi request reprint Characterization of mRNA expression in single neurons
    David M Lin
    Department of Biomedical Sciences, Cornell University, Ithaca, NY, USA
    Methods Mol Biol 399:133-52. 2007
    ..Here we provide detailed protocols for harvesting RNA from single cells, methods for RNA purification, and PCR amplification...
  11. ncbi request reprint Role of the neuropeptide CCAP in Drosophila cardiac function
    Davide Dulcis
    Division of Neurobiology, University of Arizona, 611 Gould Simpson Science Building, Tucson, Arizona 85721, USA
    J Neurobiol 64:259-74. 2005
    ..However, this reduction was not sufficient to compromise CCAP's function in ecdysis behavior and heartbeat regulation...
  12. ncbi request reprint Identification of the gene encoding bursicon, an insect neuropeptide responsible for cuticle sclerotization and wing spreading
    Elizabeth M Dewey
    Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA
    Curr Biol 14:1208-13. 2004
    ..It is the first member of the cystine knot family to have a defined function in invertebrates. Mutants show that the spectrum of bursicon actions is broader than formerly demonstrated...
  13. pmc Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2
    Ching Wei Luo
    Division of Reproductive Biology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94305 5317, USA
    Proc Natl Acad Sci U S A 102:2820-5. 2005
    ..Because bursicon subunit genes are homologous to the vertebrate bone morphogenetic protein antagonists, our findings also facilitate investigation on the function of these proteins during vertebrate development...

Research Grants2

  1. Circadian control of a behavioral output
    John Ewer; Fiscal Year: 2007
    ..Thus it offers a unique opportunity to elucidate how the activity of the clock is coupled to the mechanism that controls a behavioral output. ..