David Erickson

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Nanoporous polymer ring resonators for biosensing
    Matthew Mancuso
    Department of Biomedical Engineering, Cornell University, Ithaca, NY 14850, USA
    Opt Express 20:245-55. 2012
  2. pmc Microfabricated physical spatial gradients for investigating cell migration and invasion dynamics
    Michael Mak
    Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 6:e20825. 2011
  3. pmc High volumetric power density, non-enzymatic, glucose fuel cells
    Vlad Oncescu
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Sci Rep 3:1226. 2013
  4. pmc Solar thermal polymerase chain reaction for smartphone-assisted molecular diagnostics
    Li Jiang
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853
    Sci Rep 4:4137. 2014
  5. doi request reprint A smartphone platform for the quantification of vitamin D levels
    Seoho Lee
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 14:1437-42. 2014
  6. doi request reprint Cholesterol testing on a smartphone
    Vlad Oncescu
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 14:759-63. 2014
  7. ncbi request reprint Continuous operation of a hybrid solid-liquid state reconfigurable photonic system without resupply of liquids
    Erica Eunjung Jung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    Lab Chip 12:2575-9. 2012
  8. doi request reprint Nanomanipulation using near field photonics
    David Erickson
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA
    Lab Chip 11:995-1009. 2011
  9. pmc Enhanced on-chip SERS based biomolecular detection using electrokinetically active microwells
    Yun Suk Huh
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 9:433-9. 2009
  10. ncbi request reprint Optically induced microfluidic reconfiguration
    Mekala Krishnan
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    Lab Chip 12:613-21. 2012

Research Grants

  1. Nanoscale Optofluidic Pathogen Detection
    David Erickson; Fiscal Year: 2007

Collaborators

  • A J Baeumner
  • Aaron D Strickland
  • Li Jiang
  • Julie M Goddard
  • Carl A Batt
  • Cynthia A Reinhart-King
  • Adam J Lowe
  • Largus T Angenent
  • Peng Chen
  • Demetri Psaltis
  • Harold Craighead
  • Vlad Oncescu
  • Aram J Chung
  • Yun Suk Huh
  • Michael Mak
  • Allen H J Yang
  • Sudeep Mandal
  • Mekala Krishnan
  • Matthew Mancuso
  • Xavier Serey
  • Seoho Lee
  • Yih Fan Chen
  • Erica Eunjung Jung
  • Seung Min Park
  • Inhee Choi
  • Bernardo Cordovez
  • Abdurrahman Gumus
  • Syed Saad Ahsan
  • Peng He
  • Pilgyu Kang
  • Aadhar Jain
  • Matthew J Kennedy
  • Erica E Jung
  • Saurabh Mehta
  • Kolbeinn Karlsson
  • Matt Mancuso
  • Ethel Cesarman
  • Dakota O'Dell
  • Matthew D Ooms
  • Rupa Sarkar
  • Michael Kalontarov
  • David Sinton
  • Devin F R Doud
  • Scott J Stelick
  • Andrew Yen
  • Lavanya G Sayam
  • Daniel J Joe
  • Jun Kameoka
  • Kylan Szeto
  • Geoffrey W Coates
  • Joshua B Edel
  • Bradley S Schmidt
  • Michael T Tolley
  • Hod Lipson
  • Joonsik Park
  • Sean D Moore
  • Michal Lipson
  • Matthew Klug
  • Tadsanapan Lerdsuchatawanich
  • Donn Kim

Detail Information

Publications50

  1. pmc Nanoporous polymer ring resonators for biosensing
    Matthew Mancuso
    Department of Biomedical Engineering, Cornell University, Ithaca, NY 14850, USA
    Opt Express 20:245-55. 2012
    ..We report a 40% increase in polymer device sensitivity attributed to the addition of core energy- bioanalyte interactions...
  2. pmc Microfabricated physical spatial gradients for investigating cell migration and invasion dynamics
    Michael Mak
    Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 6:e20825. 2011
    ..Incorporation of micro-architectures in confined channels enables the probing of migration behaviors specific to defined geometries that mimic in vivo microenvironments...
  3. pmc High volumetric power density, non-enzymatic, glucose fuel cells
    Vlad Oncescu
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Sci Rep 3:1226. 2013
    ..This represents the first demonstration of a low volume non-enzymatic fuel cell stack with high power density, greatly increasing the range of applications for non-enzymatic glucose fuel cells...
  4. pmc Solar thermal polymerase chain reaction for smartphone-assisted molecular diagnostics
    Li Jiang
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853
    Sci Rep 4:4137. 2014
    ..We believe that exploiting the ubiquity of solar thermal energy as demonstrated here could facilitate broad availability of nucleic acid-based diagnostics in resource-limited areas...
  5. doi request reprint A smartphone platform for the quantification of vitamin D levels
    Seoho Lee
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 14:1437-42. 2014
    ..We envision this as the first step towards the development of the NutriPhone, a comprehensive system for the analysis of multiple vitamins and micronutrients on a smartphone. ..
  6. doi request reprint Cholesterol testing on a smartphone
    Vlad Oncescu
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 14:759-63. 2014
    ....
  7. ncbi request reprint Continuous operation of a hybrid solid-liquid state reconfigurable photonic system without resupply of liquids
    Erica Eunjung Jung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    Lab Chip 12:2575-9. 2012
    ..We believe that our system represents an important step towards the development of practical optofluidically enabled photonic systems...
  8. doi request reprint Nanomanipulation using near field photonics
    David Erickson
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA
    Lab Chip 11:995-1009. 2011
    ..In addition we highlight three application areas where these techniques namely could be of interest to the lab-on-a-chip community, namely: single molecule analysis, nanoassembly, and optical chromatography...
  9. pmc Enhanced on-chip SERS based biomolecular detection using electrokinetically active microwells
    Yun Suk Huh
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 9:433-9. 2009
    ..We report a limit of detection for Dengue sequences of 30 pM and show excellent specificity against other serotypes...
  10. ncbi request reprint Optically induced microfluidic reconfiguration
    Mekala Krishnan
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    Lab Chip 12:613-21. 2012
    ..In addition to characterizing the effect, we also apply this technique to create dynamic traps for biomolecules, and demonstrate trapping of λ-DNA molecules and nanoparticles, with a 25 fold suppression of diffusion...
  11. doi request reprint Light-governed capillary flow in microfluidic systems
    Li Jiang
    Cornell University, 240 Upson Hall, Ithaca, New York 14853, USA
    Small 9:107-14. 2013
    ..The valving dynamics are also characterised, and a response time of less than 4 s is shown. Light-operated flow could provide the simple architecture and advanced functionality needed in low-resource point-of-care devices...
  12. ncbi request reprint DNA transport and delivery in thermal gradients near optofluidic resonators
    Xavier Serey
    School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA
    Phys Rev Lett 108:048102. 2012
    ..Specifically, the region around the electromagnetic hot spot is depleted in biomolecules because of a high free energy barrier...
  13. pmc A method for nanofluidic device prototyping using elastomeric collapse
    Seung Min Park
    School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 106:15549-54. 2009
    ..The applicability of the technique to biomolecular analysis is demonstrated by showing DNA elongation in a nanochannel and a technique for optofluidic surface enhanced Raman detection of nucleic acids...
  14. doi request reprint Nanomanipulation using silicon photonic crystal resonators
    Sudeep Mandal
    School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA
    Nano Lett 10:99-104. 2010
    ..Our approach lays the groundwork for a new class of optical trapping platforms that could eventually enable complex all-optical single molecule manipulation and directed assembly of nanoscale material...
  15. doi request reprint Label-free electrochemical monitoring of vasopressin in aptamer-based microfluidic biosensors
    Peng He
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, United States
    Anal Chim Acta 759:74-80. 2013
    ..Ultimately such a system could serve as a point-of-care diagnostics tool for patients with excessive bleeding when standard medical infrastructure is not available...
  16. pmc Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device
    Michael Mak
    Biomedical Engineering Department, Cornell University, Ithaca, NY, United States
    Lab Chip 13:340-8. 2013
    ..These results illustrate that subnucleus-scaled confinement modulation can play a distinctive role in inducing behavioral responses in invading cells and can help reveal the mechanical elements of non-proteolytic invasion...
  17. pmc Controlled photonic manipulation of proteins and other nanomaterials
    Yih Fan Chen
    Kavli Institute at Cornell for Nanoscale Science, Cornell University, Ithaca, New York 14853, USA
    Nano Lett 12:1633-7. 2012
    ..3 K, which is below the point where unwanted fluid mechanical effects will prevent trapping or damage biological targets...
  18. ncbi request reprint A serial micropipette microfluidic device with applications to cancer cell repeated deformation studies
    Michael Mak
    Biomedical Engineering Department, Cornell University, Ithaca, NY 14853, USA
    Integr Biol (Camb) 5:1374-84. 2013
    ....
  19. doi request reprint Multiplex single nucleotide polymorphism genotyping utilizing ligase detection reaction coupled surface enhanced Raman spectroscopy
    Adam J Lowe
    Graduate Field of Microbiology, Cornell University, Ithaca, New York 14853, USA
    Anal Chem 82:5810-4. 2010
    ..These advances are significant as we have further developed our new SNP genotyping platform and have demonstrated the ability to correlate genotype ratios directly to diagnostic Raman peak signal intensity...
  20. doi request reprint Forces and transport velocities for a particle in a slot waveguide
    Allen H J Yang
    School of Chemical and Biomolecular Engineering, and Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York, USA
    Nano Lett 9:1182-8. 2009
    ..Our results indicate that stable trapping and transport can be achieved for objects as small as 10 or 20 nm in diameter with as much as a 100 fold enhancement in trapping stiffness over the state of the art...
  21. doi request reprint Analysis of liquid-to-solid coupling and other performance parameters for microfluidically reconfigurable photonic systems
    Erica E Jung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853 USA
    Opt Express 18:10973-84. 2010
    ..g. unchangeable structure and properties) and liquid waveguide systems (e.g. diversion and attenuation) yielding a new paradigm for reconfigurable photonics...
  22. pmc Nanoscale optofluidic sensor arrays
    Sudeep Mandal
    School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
    Opt Express 16:1623-31. 2008
    ..While other techniques such as SPR possess a equivalent RI detection limit, the advantage of this architecture lies in its potential for low mass limit of detection which is enabled by confining the size of the probed surface area...
  23. doi request reprint Rapid prototyping of nanofluidic systems using size-reduced electrospun nanofibers for biomolecular analysis
    Seung Min Park
    School of Applied and Engineering Physics, Cornell University, 205 Clark Hall, Ithaca, NY 14853, USA
    Small 6:2420-6. 2010
    ....
  24. doi request reprint Slab waveguide photobioreactors for microalgae based biofuel production
    Erica Eunjung Jung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 12:3740-5. 2012
    ..We also show that the stackable nature of the slab waveguide approach could yield a 12-fold improvement in the volumetric productivity...
  25. doi request reprint Angular orientation of nanorods using nanophotonic tweezers
    Pilgyu Kang
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, United States
    Nano Lett 12:6400-7. 2012
    ..8 pN·nm/rad(2)·mW is measured for the nanotubes. We expect that this new capability will facilitate the development of high precision nanoassembly schemes and biophysical studies of bending strains of biomolecules...
  26. doi request reprint Optofluidic waveguides for reconfigurable photonic systems
    Aram J Chung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    Opt Express 19:8602-9. 2011
    ..1-10.7 dB, operability over a broad bandwidth spanning the range of wavelengths from visible to telecommunication, and a 1x2 sub-second switching system with a cross-talk as low as 20 dB and maximum coupling efficiency of 3.87 dB...
  27. doi request reprint Large area flexible SERS active substrates using engineered nanostructures
    Aram J Chung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Nanoscale 3:2903-8. 2011
    ..In addition, we present experimental results showing how a hybrid structure comprising of gold nanospheres embedded in a silver nano-pillar structure can be used to obtain a 50× SERS enhancement over the raw nanoparticles themselves...
  28. doi request reprint A multiplexed optofluidic biomolecular sensor for low mass detection
    Sudeep Mandal
    School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 9:2924-32. 2009
    ..The multiplexing capabilities of our sensor are demonstrated by the individual and concurrent detection of interleukins 4, 6 and 8 using a sandwich assay...
  29. doi request reprint Electroactive micro and nanowells for optofluidic storage
    Bernardo Cordovez
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Opt Express 17:21134-48. 2009
    ..We envision that this technique could find eventual application in fluidic memory or display devices...
  30. pmc Aptamer based surface enhanced Raman scattering detection of vasopressin using multilayer nanotube arrays
    Yun Suk Huh
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Biosens Bioelectron 25:1240-3. 2010
    ..This low limit of detection is obtained with device containing the multilayer SERS substrate which we show exhibits a stronger Raman enhancement while maintaining biocompatibility and ease or surface reactivity with the capture probe...
  31. doi request reprint Optical manipulation of nanoparticles and biomolecules in sub-wavelength slot waveguides
    Allen H J Yang
    School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 14853, USA
    Nature 457:71-5. 2009
    ..We also carry out a detailed numerical analysis that relates the near-field optical forces to release kinetics. We believe that the architecture demonstrated here will help to bridge the gap between optical manipulation and nanofluidics...
  32. pmc Biopatterning for label-free detection
    Julie M Goddard
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Colloids Surf B Biointerfaces 76:375-80. 2010
    ....
  33. pmc Bioconjugation techniques for microfluidic biosensors
    Julie M Goddard
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Anal Bioanal Chem 394:469-79. 2009
    ....
  34. pmc Multiplexed colorimetric detection of Kaposi's sarcoma associated herpesvirus and Bartonella DNA using gold and silver nanoparticles
    Matthew Mancuso
    Department of Biomedical Engineering, Cornell University, Ithaca, NY, USA
    Nanoscale 5:1678-86. 2013
    ..The system developed here could later be integrated with microfluidic sample processing to create a final device capable of solving the two major challenges in point-of-care KS detection...
  35. doi request reprint Size-selective concentration and label-free characterization of protein aggregates using a Raman active nanofluidic device
    Inhee Choi
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 11:632-8. 2011
    ..We expect that our method could facilitate definitive diagnosis and possible therapeutics of diseases at early stages...
  36. doi request reprint Smartphone based health accessory for colorimetric detection of biomarkers in sweat and saliva
    Vlad Oncescu
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 13:3232-8. 2013
    ..Additionally, we perform trials to measure salivary pH over time to monitor the effects of diet on oral health risks. ..
  37. doi request reprint Gel-based optical waveguides with live cell encapsulation and integrated microfluidics
    Aadhar Jain
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    Opt Lett 37:1472-4. 2012
    ..We characterize the optical properties of the waveguide and further incorporate a microfluidic channel over the optical structure, thus developing an integrated optofluidic system fabricated entirely from agarose gel...
  38. doi request reprint A robust, electrochemically driven microwell drug delivery system for controlled vasopressin release
    Aram J Chung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Biomed Microdevices 11:861-7. 2009
    ..The concentration profile vs. time, the power consumption, and ejection efficiency are also investigated. To demonstrate the medical utility of the device we also characterize the in-vitro release of vasopressin...
  39. doi request reprint Engineering insect flight metabolics using immature stage implanted microfluidics
    Aram J Chung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 9:669-76. 2009
    ..Behavior ranging from retarded motion to complete, reversible paralysis, over timescales ranging from minutes to hours is demonstrated...
  40. pmc Autonomous device for application in late-phase hemorrhagic shock prevention
    Vlad Oncescu
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 9:e89903. 2014
    ..We demonstrate that the device can operate at physiological concentrations of vasopressin, in sheep serum, thus paving the way towards the development of an autonomous implantable device for HS prevention. ..
  41. pmc Hydrodynamic optical alignment for microflow cytometry
    Matthew J Kennedy
    Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 11:1138-43. 2011
    ..The device exhibited a linear response to fluorescence intensity calibration microparticles as shown by comparison with a commercial cytometer instrument...
  42. pmc Surface-enhanced Raman scattering based ligase detection reaction
    Yun Suk Huh
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA
    J Am Chem Soc 131:2208-13. 2009
    ..We report a limit of detection of 20 pM of target DNA with the anticipated specificity engendered by the LDR platform...
  43. doi request reprint Redox mediated photocatalytic water-splitting in optofluidic microreactors
    Syed Saad Ahsan
    Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 13:409-14. 2013
    ..In particular, for TiO(2)-Pt, we show ~2-fold improvements in reaction rates and efficiencies...
  44. ncbi request reprint Directed self-assembly of microcomponents enabled by laser-activated bubble latching
    Li Jiang
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, 240 Upson Hall, Ithaca, New York 14853, USA
    Langmuir 27:11259-64. 2011
    ..Furthermore, we show reconfiguration capabilities through the use of bubble hinging. This novel hybrid approach to the assembly of microscale components offers significant user control while retaining a simplistic design environment...
  45. doi request reprint Mechanical decision trees for investigating and modulating single-cell cancer invasion dynamics
    Michael Mak
    Biomedical Engineering Department, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 14:964-71. 2014
    ..We then implement strategies based purely on mechanical asymmetries to induce repetitive, non-disseminating motions, in a phenomenon we call iteratio ad nauseam. ..
  46. ncbi request reprint Stability analysis of optofluidic transport on solid-core waveguiding structures
    Allen H J Yang
    School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14850, USA
    Nanotechnology 19:045704. 2008
    ....
  47. ncbi request reprint Optothermorheological flow manipulation
    Mekala Krishnan
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Opt Lett 34:1976-8. 2009
    ..In our approach a laser beam incident on an absorbing substrate is used to locally heat a thermorheological fluid flowing in a microfluidic channel. The resulting gelation in the heated region creates a reversible fluid valve...
  48. ncbi request reprint Hydrodynamically tunable affinities for fluidic assembly
    Mekala Krishnan
    Sibley School of Mechanical and Aerospace Engineering and Computing and Information Science, Cornell University, Ithaca, New York 14853, USA
    Langmuir 25:3769-74. 2009
    ..Although this technique is demonstrated here for a small number of passive mobile components around a fixed structure, it has the potential to overcome some of the limitations of current static affinity based self-assembly...
  49. ncbi request reprint Optofluidic ring resonator switch for optical particle transport
    Allen H J Yang
    Cornell University, Ithaca, USA
    Lab Chip 10:769-74. 2010
    ..The optofluidic switch we present here demonstrates the versatility in exploiting planar optical devices for integrated particle manipulation applications...
  50. doi request reprint Electrokinetic microfluidic devices for rapid, low power drug delivery in autonomous microsystems
    Aram J Chung
    Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY 14853, USA
    Lab Chip 8:330-8. 2008
    ..This paper focuses on presenting the design and characterizing the electrokinetic transport mechanics which govern the release time and dispersal pattern of the well contents using a series of experimental and numerical techniques...

Research Grants2

  1. Nanoscale Optofluidic Pathogen Detection
    David Erickson; Fiscal Year: 2007
    ..The near term major application will be as an early stage detection platform. ..