ERIC DENKERS

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages
    Jin Leng
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 4:e7589. 2009
  2. pmc Synergy between intraepithelial lymphocytes and lamina propria T cells drives intestinal inflammation during infection
    C E Egan
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Mucosal Immunol 4:658-70. 2011
  3. pmc CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection
    Sara B Cohen
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
    PLoS Pathog 9:e1003706. 2013
  4. pmc Neutrophils cast extracellular traps in response to protozoan parasites
    Delbert S Abi Abdallah
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University Ithaca, NY, USA
    Front Immunol 3:382. 2012
  5. pmc Toxoplasma gondii triggers phosphorylation and nuclear translocation of dendritic cell STAT1 while simultaneously blocking IFNγ-induced STAT1 transcriptional activity
    Anne G Schneider
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 8:e60215. 2013
  6. ncbi request reprint Deploying parasite profilin on a mission of invasion and danger
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Cell Host Microbe 3:61-3. 2008
  7. doi request reprint A gut feeling for microbes: getting it going between a parasite and its host
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Cell Host Microbe 6:104-6. 2009
  8. ncbi request reprint Sabotage and exploitation in macrophages parasitized by intracellular protozoans
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Trends Parasitol 21:35-41. 2005
  9. ncbi request reprint Manipulation of mitogen-activated protein kinase/nuclear factor-kappaB-signaling cascades during intracellular Toxoplasma gondii infection
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    Immunol Rev 201:191-205. 2004
  10. ncbi request reprint Neutrophils, dendritic cells and Toxoplasma
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Int J Parasitol 34:411-21. 2004

Research Grants

  1. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2000
  2. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2006
  3. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2006
  4. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2007
  5. Role of CCL2/MCP-1 in mucosal immunity to Toxoplasma
    ERIC DENKERS; Fiscal Year: 2007
  6. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2009
  7. Immunobiology of Parasitic Diseases
    ERIC DENKERS; Fiscal Year: 2005
  8. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2005
  9. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2001
  10. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2002

Collaborators

Detail Information

Publications42

  1. pmc Toxoplasma gondii inhibits covalent modification of histone H3 at the IL-10 promoter in infected macrophages
    Jin Leng
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 4:e7589. 2009
    ..These results provide compelling evidence that T. gondii targets the host cell chromatin remodeling machinery to down-regulate cytokine responses in infected macrophages...
  2. pmc Synergy between intraepithelial lymphocytes and lamina propria T cells drives intestinal inflammation during infection
    C E Egan
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Mucosal Immunol 4:658-70. 2011
    ..Our data provide valuable new insights into the mechanisms of intestinal inflammation, findings that have important implications for understanding human inflammatory bowel disease...
  3. pmc CXCR3-dependent CD4⁺ T cells are required to activate inflammatory monocytes for defense against intestinal infection
    Sara B Cohen
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
    PLoS Pathog 9:e1003706. 2013
    ..Our results establish a central role for CXCR3 in coordinating innate and adaptive immunity, ensuring generation of Th1 effectors and their trafficking to the frontline of infection to program microbial killing by inflammatory monocytes...
  4. pmc Neutrophils cast extracellular traps in response to protozoan parasites
    Delbert S Abi Abdallah
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University Ithaca, NY, USA
    Front Immunol 3:382. 2012
    ..The present review summarizes findings to date regarding elicitation of NETs by Toxoplasma gondii, Plasmodium falciparum, Eimeria bovis, and Leishmania spp...
  5. pmc Toxoplasma gondii triggers phosphorylation and nuclear translocation of dendritic cell STAT1 while simultaneously blocking IFNγ-induced STAT1 transcriptional activity
    Anne G Schneider
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 8:e60215. 2013
    ..These results reinforce the importance of parasite-mediated blockade of IFNγ responses in dendritic cells, while simultaneously showing that T. gondii alone induces STAT1 phosphorylation...
  6. ncbi request reprint Deploying parasite profilin on a mission of invasion and danger
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Cell Host Microbe 3:61-3. 2008
    ....
  7. doi request reprint A gut feeling for microbes: getting it going between a parasite and its host
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Cell Host Microbe 6:104-6. 2009
    ..Benson et al. (2009) suggest that host sensing of these microbes takes a pivotal role in getting the immune system up and running in response to a major intestinal parasite...
  8. ncbi request reprint Sabotage and exploitation in macrophages parasitized by intracellular protozoans
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Trends Parasitol 21:35-41. 2005
    ..The molecular details of how intracellular protozoans manipulate macrophage signal transduction pathways for their own ends are beginning to emerge...
  9. ncbi request reprint Manipulation of mitogen-activated protein kinase/nuclear factor-kappaB-signaling cascades during intracellular Toxoplasma gondii infection
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    Immunol Rev 201:191-205. 2004
    ..The balance between activation and interference with proinflammatory signaling is likely to reflect the need to achieve an appropriate level of immunity that allows the host and parasite to maintain a stable interaction...
  10. ncbi request reprint Neutrophils, dendritic cells and Toxoplasma
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Int J Parasitol 34:411-21. 2004
    ..Neutrophil-empowered dendritic cells possess properties expected of highly potent antigen presenting cells that drive T helper 1 generation...
  11. pmc Toll-like receptor initiated host defense against Toxoplasma gondii
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Biomed Biotechnol 2010:737125. 2010
    ..These responses can be triggered by the parasite itself, but interactions with the intestinal microbiota add additional complexity during enteric infection...
  12. pmc Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection
    E Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Clin Microbiol Rev 11:569-88. 1998
    ..While part of the clinical manifestations of toxoplasmosis results from direct tissue destruction by the parasite, inflammatory cytokine-mediated immunopathologic changes may also contribute to disease progression...
  13. ncbi request reprint From cells to signaling cascades: manipulation of innate immunity by Toxoplasma gondii
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    FEMS Immunol Med Microbiol 39:193-203. 2003
    ..The widespread distribution of T. gondii and the normally innocuous nature of infection indicate the skill with which the parasite achieves the two seemingly contrary goals...
  14. pmc Toxoplasma gondii triggers release of human and mouse neutrophil extracellular traps
    Delbert S Abi Abdallah
    Department of Microbiology and Immunology, Cornell University, Ithaca, New York, USA
    Infect Immun 80:768-77. 2012
    ..We propose that NET formation limits infection by direct microbicidal effects on Toxoplasma as well as by interfering with the ability of the parasite to invade target host cells...
  15. ncbi request reprint Neutrophil production of IL-12 and other cytokines during microbial infection
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Chem Immunol Allergy 83:95-114. 2003
  16. pmc An inside job: hacking into Janus kinase/signal transducer and activator of transcription signaling cascades by the intracellular protozoan Toxoplasma gondii
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Infect Immun 80:476-82. 2012
    ....
  17. ncbi request reprint In the belly of the beast: subversion of macrophage proinflammatory signalling cascades during Toxoplasma gondii infection
    Eric Y Denkers
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Cell Microbiol 5:75-83. 2003
    ..The balance of cytokine subversion and stimulation during infection probably results from the parasite's need to simultaneously avoid immune elimination and trigger immunity to prevent host death...
  18. ncbi request reprint Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors
    Laura Del Rio
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA
    J Immunol 172:6954-60. 2004
    ..gondii possesses multiple molecules triggering distinct MyD88-dependent signaling cascades, that these pathways are independently regulated, and that they lead to distinct profiles of cytokine production...
  19. ncbi request reprint Cross-talk in the innate immune system: neutrophils instruct recruitment and activation of dendritic cells during microbial infection
    Soumaya Bennouna
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Immunol 171:6052-8. 2003
    ....
  20. pmc STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection
    L Cristina Gavrilescu
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Infect Immun 72:1257-64. 2004
    ....
  21. ncbi request reprint p38 MAPK autophosphorylation drives macrophage IL-12 production during intracellular infection
    Leesun Kim
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    J Immunol 174:4178-84. 2005
    ..Furthermore, a synthetic p38 catalytic-site inhibitor blocked tachyzoite-induced p38alpha MAPK phosphorylation. These data are the first to demonstrate p38 MAPK autophosphorylation triggered by intracellular infection...
  22. ncbi request reprint Microbial antigen triggers rapid mobilization of TNF-alpha to the surface of mouse neutrophils transforming them into inducers of high-level dendritic cell TNF-alpha production
    Soumaya Bennouna
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    J Immunol 174:4845-51. 2005
    ..The data suggest that microbial Ag-triggered mouse PMN acquire the capacity to deliver potent DC-activating signals through elaboration of cytokines and direct interactions at the cell surface...
  23. ncbi request reprint Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages
    Leesun Kim
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Immunol 177:2584-91. 2006
    ..Differences in host signaling pathways triggered by RH vs ME49 may contribute to the high and low virulence characteristics displayed by these parasite strains...
  24. ncbi request reprint Toxoplasma gondii interferes with lipopolysaccharide-induced mitogen-activated protein kinase activation by mechanisms distinct from endotoxin tolerance
    Leesun Kim
    Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA
    J Immunol 172:3003-10. 2004
    ..Our results show that T. gondii blocks LPS-triggered cytokine production in part through MAPK inactivation, and that this occurs through pathways distinct from endotoxin-induced tolerance...
  25. pmc Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production
    Barbara A Butcher
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Infect Immun 70:5216-24. 2002
    ..They also show that the effects of Toxoplasma on IL-12 and TNF-alpha production are nonidentical, with the parasite exerting a longer-lasting suppression of the latter...
  26. pmc Interleukin-12 p40- and Fas ligand-dependent apoptotic pathways involving STAT-1 phosphorylation are triggered during infection with a virulent strain of Toxoplasma gondii
    L Cristina Gavrilescu
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Infect Immun 71:2577-83. 2003
    ..The results demonstrate T. gondii-induced activation of multiple apoptotic pathways, dependent upon both IL-12 p40 and FasL, that may play a role in the lethal pathology of infection...
  27. pmc Toxoplasma gondii prevents chromatin remodeling initiated by TLR-triggered macrophage activation
    Jin Leng
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Immunol 182:489-97. 2009
    ....
  28. pmc Dendritic cells expressing plasmacytoid marker PDCA-1 are Trojan horses during Toxoplasma gondii infection
    Allison L Bierly
    Department of Microbiology and Immunology, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA
    J Immunol 181:8485-91. 2008
    ..We hypothesize that Toxoplasma exploits pDCs as Trojan horses, targeting them for early infection, suppressing their cytokine effector function, and using them for dissemination within the host...
  29. pmc Toxoplasma gondii inhibits toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils
    Soumaya Bennouna
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Infect Immun 74:4274-81. 2006
    ..Collectively, the results show that Toxoplasma prevents TLR ligand-triggered mobilization of TNF-alpha to the neutrophil surface, revealing a novel immunosuppressive activity of the parasite...
  30. ncbi request reprint Toxoplasma gondii triggers Gi-dependent PI 3-kinase signaling required for inhibition of host cell apoptosis
    Leesun Kim
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    J Cell Sci 119:2119-26. 2006
    ..This study demonstrates that T. gondii exploits host Gi-protein-dependent PI 3-kinase signaling to prevent induction of apoptosis in infected macrophages...
  31. pmc Phosphoinositide-3-kinase-dependent, MyD88-independent induction of CC-type chemokines characterizes the macrophage response to Toxoplasma gondii strains with high virulence
    Chiang W Lee
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Infect Immun 75:5788-97. 2007
    ....
  32. ncbi request reprint IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages
    Barbara A Butcher
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Immunol 174:3148-52. 2005
    ..gondii exploits host STAT3 to prevent LPS-triggered IL-12 and TNF-alpha production, revealing for the first time a molecular mechanism underlying the parasite's suppressive effect on macrophage proinflammatory cytokine production...
  33. pmc p47 GTPases regulate Toxoplasma gondii survival in activated macrophages
    Barbara A Butcher
    Dept of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
    Infect Immun 73:3278-86. 2005
    ..gondii. These results suggest that IGTP and LRG-47 are able to regulate host resistance to acute T. gondii infections through their ability to inhibit parasite growth within the macrophage...
  34. pmc Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages
    Chiang W Lee
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Infect Immun 74:1916-23. 2006
    ..We suggest that these effects represent parasite defense mechanisms to avoid or delay induction of antimicrobial activity and/or T-cell-mediated immunity during Toxoplasma infection...
  35. ncbi request reprint Mouse neutrophils require JNK2 MAPK for Toxoplasma gondii-induced IL-12p40 and CCL2/MCP-1 release
    Woraporn Sukhumavasi
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Immunol 179:3570-7. 2007
    ....
  36. doi request reprint Understanding the multiple functions of Gr-1(+) cell subpopulations during microbial infection
    Charlotte E Egan
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853 6401, USA
    Immunol Res 40:35-48. 2008
    ..We focus on infection with the opportunistic protozoan Toxoplasma gondii, a case where host survival depends on an intact Gr-1(+) cell population...
  37. pmc TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite
    Woraporn Sukhumavasi
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    J Immunol 181:3464-73. 2008
    ..gondii strain. Our results demonstrate that MyD88 is required to control Toxoplasma infection, but that the parasite can trigger adaptive immunity without the need for this TLR adaptor molecule...
  38. pmc Apoptosis and the balance of homeostatic and pathologic responses to protozoan infection
    L Cristina Gavrilescu
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 6401, USA
    Infect Immun 71:6109-15. 2003
  39. ncbi request reprint CD154 plays a central role in regulating dendritic cell activation during infections that induce Th1 or Th2 responses
    Amy D Straw
    Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia 19104, USA
    J Immunol 170:727-34. 2003
    ..However, the ability of this activation pathway to induce IL-12 production by DC is restrained in S. mansoni-infected, but not T. gondii-infected, mice by Ag-responsive CD11c(-) cells...
  40. ncbi request reprint Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells
    Charles A Scanga
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 168:5997-6001. 2002
    ..Taken together, these data suggest that the induction of IL-12 by T. gondii depends on a unique mechanism involving both MyD88 and G protein-coupled signaling pathways...
  41. ncbi request reprint Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
    Ricardo T Gazzinelli
    Department of Biochemistry and Immunology, Federal University of Minas Gerais, 31270 901 Belo Horizonte, Brazil
    Nat Rev Immunol 6:895-906. 2006
    ..This Review describes recent insights into how parasitic protozoans are sensed by TLR molecules, and how the TLR system itself can be targeted by these microbial pathogens for their own survival...

Research Grants20

  1. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2000
    ..abstract_text> ..
  2. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2006
    ..Understanding the molecular pathology of infection will lead to better control strategies for this and related microbial pathogens. ..
  3. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2006
    ..Understanding how immunity is triggered can be expected to lead to more effective means of controlling infection with Toxoplasma and other microbial pathogens. ..
  4. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2007
    ..Understanding how immunity is triggered can be expected to lead to more effective means of controlling infection with Toxoplasma and other microbial pathogens. ..
  5. Role of CCL2/MCP-1 in mucosal immunity to Toxoplasma
    ERIC DENKERS; Fiscal Year: 2007
    ..This project will enhance our understanding of immunity to the parasite, leading to improved treatment strategies. ..
  6. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2009
    ..This project will enhance our understanding of immunity to the parasite, leading to improved treatment strategies. ..
  7. Immunobiology of Parasitic Diseases
    ERIC DENKERS; Fiscal Year: 2005
    ..Existing support for the program is substantial in the form of research environment and facilities, the Cornell Biotechnology Program and computing and library systems ..
  8. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2005
    ..Understanding how immunity is triggered can be expected to lead to more effective means of controlling infection with Toxoplasma and other microbial pathogens. ..
  9. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2001
    ..abstract_text> ..
  10. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2002
    ..Understanding the molecular pathology of infection will lead to better control strategies for this and related microbial pathogens. ..
  11. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2002
    ..abstract_text> ..
  12. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2003
    ..abstract_text> ..
  13. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2003
    ..Understanding the molecular pathology of infection will lead to better control strategies for this and related microbial pathogens. ..
  14. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2004
    ..Understanding the molecular pathology of infection will lead to better control strategies for this and related microbial pathogens. ..
  15. ROLE OF NEUTROPHILS DURING TOXOPLASMOSIS
    ERIC DENKERS; Fiscal Year: 2004
    ..Understanding how immunity is triggered can be expected to lead to more effective means of controlling infection with Toxoplasma and other microbial pathogens. ..
  16. Signal transduction during Toxoplasma infection
    ERIC DENKERS; Fiscal Year: 2005
    ..Understanding the molecular pathology of infection will lead to better control strategies for this and related microbial pathogens. ..
  17. Signal transduction during Toxoplasma infection
    Eric Y Denkers; Fiscal Year: 2010
    ..This project will enhance our understanding of immunity to the parasite, leading to improved treatment strategies. ..