Research Topics
Genomes and GenesSpecies | K W BeyenbachSummaryAffiliation: Cornell University Country: USA Publications
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Detail Information
Publications
The developmental, molecular, and transport biology of Malpighian tubulesKlaus W Beyenbach
Department of Biomedical Sciences, Cornell University, Ithaca, New York 14853, USA
Annu Rev Entomol 55:351-74. 2010....
A dynamic paracellular pathway serves diuresis in mosquito Malpighian tubulesKlaus W Beyenbach
Department of Biomedical Sciences, Cornell University, Ithaca, New York, USA
Ann N Y Acad Sci 1258:166-76. 2012....
Transcellular and paracellular pathways of transepithelial fluid secretion in Malpighian (renal) tubules of the yellow fever mosquito Aedes aegyptiK W Beyenbach
Department of Biomedical Sciences, VRT 8004, Cornell University, Ithaca, NY, USA
Acta Physiol (Oxf) 202:387-407. 2011..Septate junctions define the properties of the paracellular pathway in Malpighian tubules, but the proteins responsible for the permselectivity and barrier functions of the septate junction are unknown...
Signaling to the apical membrane and to the paracellular pathway: changes in the cytosolic proteome of Aedes Malpighian tubulesKlaus W Beyenbach
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 212:329-40. 2009..The effects of AK-III on active transcellular and passive paracellular transport are additive, if not synergistic, to bring about the rapid diuresis...
The V-type H+ ATPase: molecular structure and function, physiological roles and regulationKlaus W Beyenbach
Department of Biomedical Sciences, VRT 8004, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 209:577-89. 2006..Some diseases can now be attributed to genetic alterations of specific subunits of the V-type H+ ATPase...
Kidneys sans glomeruliKlaus W Beyenbach
Department of Biomedical Sciences, VRT 8004, Cornell University, Ithaca, NY 14853, USA
Am J Physiol Renal Physiol 286:F811-27. 2004....
Transport mechanisms of diuresis in Malpighian tubules of insectsKlaus W Beyenbach
Department of Biomedical Sciences, VRT 8004, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 206:3845-56. 2003....
Regulation of tight junction permeability with switch-like speedKlaus W Beyenbach
Department of Biomedical Sciences, Cornell University, Ithaca, New York 14853, USA
Curr Opin Nephrol Hypertens 12:543-50. 2003....
Central role of the apical membrane H+-ATPase in electrogenesis and epithelial transport in Malpighian tubulesK W Beyenbach
Department of Biomedical Sciences, VRT 8014, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 203:1459-68. 2000..Furthermore, electrical coupling offers a balance between electroconductive entry of cations across the basolateral membrane and extrusion across the apical membrane to support steady-state conditions during transepithelial transport...
Renal handling of magnesium in fish: from whole animal to brush border membrane vesiclesK W Beyenbach
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
Front Biosci 5:D712-9. 2000..New methods, including Mg imaging and genetic/molecular approaches promise to unravel Mg transport mechanisms in teleost renal tubules...
Energizing epithelial transport with the vacuolar H(+)-ATPaseK W Beyenbach
Department of Biomedical Sciences, Cornell University, Ithaca, New York 14853, USA
News Physiol Sci 16:145-51. 2001..A pure electrogenic pump, the V-type H(+)-ATPase energizes not only membranes it inhabits but also other transport pathways via electrical coupling...
The single kinin receptor signals to separate and independent physiological pathways in Malpighian tubules of the yellow fever mosquitoStephen A Schepel
Dept of Biomedical Sciences, VRT 8004, Cornell Univ, Ithaca, NY 14853, USA
Am J Physiol Regul Integr Comp Physiol 299:R612-22. 2010..Occasionally, Malpighian tubules did not exhibit a detectable response to natural and synthetic kinins. Hypothetically, the expression of the kinin receptor may depend on developmental, nutritional, and/or reproductive signals...
Natriuretic peptides and the acclimation of aglomerular toadfish to hypo-osmotic mediaM D Baustian
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
J Comp Physiol B 169:507-14. 1999..In the absence of glomeruli, this tubular natriuresis may be regulated by natriuretic peptides present in the kidney...
Gap junctions in Malpighian tubules of Aedes aegyptiXing He Weng
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 211:409-22. 2008....
The V-type H(+)-ATPase in Malpighian tubules of Aedes aegypti: localization and activityXing-He Weng
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 206:2211-9. 2003..Measures of transepithelial Na(+) and K(+) secretion and estimates of the H(+) flux mediated by the V-type H(+)-ATPase suggest a 1:1 stoichiometry for Na(+)/H(+) and K(+)/H(+) exchange transport across the apical membrane...
Mechanisms of K+ transport across basolateral membranes of principal cells in Malpighian tubules of the yellow fever mosquito, Aedes aegyptiBrett N Scott
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 207:1655-63. 2004....
The mechanism of action of the antidiuretic peptide Tenmo ADFa in Malpighian tubules of Aedes aegyptiRichard C Massaro
Department of Biomedical Sciences, VRT 8004, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 207:2877-88. 2004..The inhibition reveals that as much as 50% of the normal secretory solute and water flux can stem from electrically silent mechanisms in this highly electrogenic epithelium...
NHE8 is an intracellular cation/H+ exchanger in renal tubules of the yellow fever mosquito Aedes aegyptiPeter M Piermarini
Cornell Univ, College of Veterinary Medicine, Dept of Biomedical Sciences, Ithaca, NY 14853, USA
Am J Physiol Renal Physiol 296:F730-50. 2009..In conclusion, AeNHE8 does not mediate cation/H(+) exchange in the apical membrane of Aedes Malpighian tubules; it is more likely involved with an intracellular function...
The dependence of electrical transport pathways in Malpighian tubules on ATPDaniel S Wu
Department of Biomedical Sciences, VRT 8014, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 206:233-43. 2003..Intracellular K(+) homeostasis is thus protected during metabolic inhibition, allowing the cell to re-establish K(+) transport when ATP is synthesized again...
A SLC4-like anion exchanger from renal tubules of the mosquito (Aedes aegypti): evidence for a novel role of stellate cells in diuretic fluid secretionPeter M Piermarini
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
Am J Physiol Regul Integr Comp Physiol 298:R642-60. 2010..In conclusion, Aedes Malpighian tubules express AeAE in the basal region of stellate cells, where this transporter may participate in producing diuretic rates of transepithelial fluid secretion...
Chloride channels in apical membrane patches of stellate cells of Malpighian tubules of Aedes aegyptiK W Beyenbach
Department of Biomedical Sciences, VRT 8014, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 204:367-78. 2001....
Leucokinin activates Ca(2+)-dependent signal pathway in principal cells of Aedes aegypti Malpighian tubulesMing-Jiun Yu
Department of Biomedical Sciences, Cornell University, Ithaca, New York 14853, USA
Am J Physiol Renal Physiol 283:F499-508. 2002..Store depletion may then bring about Ca(2+) entry into principal cells via nifedipine-sensitive Ca(2+) channels in the basolateral membrane...
Effects of leucokinin-VIII on Aedes Malpighian tubule segments lacking stellate cellsMing-Jiun Yu
Department of Biomedical Sciences, VRT 8004, Cornell University, Ithaca, NY 14853, USA
J Exp Biol 207:519-26. 2004..The results further support previous observations that principal cells signal the effects of leucokinin to increase the Cl(-) conductance of the paracellular pathway through septate (or tight) junctions...
Cultured monolayers of the dog jejunum with the structural and functional properties resembling the normal epitheliumXing-He Weng
Dept. of Biomedical Sciences, VRT 8004, Cornell Univ, Ithaca, NY 14853, USA
Am J Physiol Gastrointest Liver Physiol 288:G705-17. 2005....
Interactions of tight junctions with membrane channels and transportersSigrid A Rajasekaran
The Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles, CA 90095, USA
Biochim Biophys Acta 1778:757-69. 2008..In this review we have attempted to compile literature on ion transporters and channels involved in the regulation of tight junctions...
