S J Bedford-Guaus

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Microinjection of mouse phospholipase C zeta complementary RNA into mare oocytes induces long-lasting intracellular calcium oscillations and embryonic development
    Sylvia J Bedford-Guaus
    Department of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, NY 14853, USA
    Reprod Fertil Dev 20:875-83. 2008
  2. doi request reprint Molecular cloning and characterization of phospholipase C zeta in equine sperm and testis reveals species-specific differences in expression of catalytically active protein
    S J Bedford-Guaus
    Departments of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Biol Reprod 85:78-88. 2011
  3. doi request reprint A defined medium supports changes consistent with capacitation in stallion sperm, as evidenced by increases in protein tyrosine phosphorylation and high rates of acrosomal exocytosis
    L A McPartlin
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States
    Theriogenology 69:639-50. 2008
  4. pmc Guanine-nucleotide exchange factors (RAPGEF3/RAPGEF4) induce sperm membrane depolarization and acrosomal exocytosis in capacitated stallion sperm
    L A McPartlin
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Biol Reprod 85:179-88. 2011
  5. doi request reprint Hyperactivation of stallion sperm is required for successful in vitro fertilization of equine oocytes
    L A McPartlin
    Departments of Clinical Sciences and Biological and Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Biol Reprod 81:199-206. 2009
  6. doi request reprint Premature luteal regression in a pregnant mare and subsequent pregnancy maintenance with the use of oral altrenogest
    I F Canisso
    Section of Theriogenology, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, New York, NY, USA
    Equine Vet J 45:97-100. 2013

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Microinjection of mouse phospholipase C zeta complementary RNA into mare oocytes induces long-lasting intracellular calcium oscillations and embryonic development
    Sylvia J Bedford-Guaus
    Department of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, NY 14853, USA
    Reprod Fertil Dev 20:875-83. 2008
    ....
  2. doi request reprint Molecular cloning and characterization of phospholipase C zeta in equine sperm and testis reveals species-specific differences in expression of catalytically active protein
    S J Bedford-Guaus
    Departments of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Biol Reprod 85:78-88. 2011
    ..Moreover, some of these results may suggest potential novel roles for PLCZ in sperm physiology...
  3. doi request reprint A defined medium supports changes consistent with capacitation in stallion sperm, as evidenced by increases in protein tyrosine phosphorylation and high rates of acrosomal exocytosis
    L A McPartlin
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States
    Theriogenology 69:639-50. 2008
    ..The continuation of these studies might help to elucidate the conditions and pathways supporting sperm capacitation in the horse...
  4. pmc Guanine-nucleotide exchange factors (RAPGEF3/RAPGEF4) induce sperm membrane depolarization and acrosomal exocytosis in capacitated stallion sperm
    L A McPartlin
    Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    Biol Reprod 85:179-88. 2011
    ..Altogether, these experiments support the hypothesis that RAPGEF3/RAPGEF4 activation regulates acrosomal exocytosis via its modulation of E(m), a novel role for RAPGEF3/RAPGEF4 in the series of events required to achieve fertilization...
  5. doi request reprint Hyperactivation of stallion sperm is required for successful in vitro fertilization of equine oocytes
    L A McPartlin
    Departments of Clinical Sciences and Biological and Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    Biol Reprod 81:199-206. 2009
    ..Conversely, sperm incubated in capacitating conditions but not treated with procaine did not fertilize (0%). These results support the hypothesis that capacitation and hyperactivation are required for successful IVF in the equine...
  6. doi request reprint Premature luteal regression in a pregnant mare and subsequent pregnancy maintenance with the use of oral altrenogest
    I F Canisso
    Section of Theriogenology, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, New York, NY, USA
    Equine Vet J 45:97-100. 2013
    ..Although progesterone concentration did not exceed 2 ng/ml until 72 days post ovulation, all other results were unremarkable and a healthy filly was born uneventfully at 344 days post ovulation...