Affiliation: Cornell University
- Low nutrient intake is an essential component of frailty in older personsBenedetta Bartali
Division of Nutritional Sciences, Cornell University, Ithaca, New York 14853 6301, USA
J Gerontol A Biol Sci Med Sci 61:589-93. 2006..Poor nutrient intake is conceptualized to be a component of frailty, but this hypothesis has been little investigated. We examined the association between low energy and nutrient intake and frailty...
- Low micronutrient levels as a predictor of incident disability in older womenBenedetta Bartali
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853 6301, USA
Arch Intern Med 166:2335-40. 2006..The role of nutritional status in the disablement process is still unclear. The objective of this study was to assess whether low concentrations of nutrients predict the development and course of disability...
- Serum micronutrient concentrations and decline in physical function among older personsBenedetta Bartali
Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
JAMA 299:308-15. 2008..The potential deleterious effect of poor nutrition on decline in physical function in older persons is unclear...
- Low serum micronutrient concentrations predict frailty among older women living in the communityRichard D Semba
The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Gerontol A Biol Sci Med Sci 61:594-9. 2006..Micronutrient deficiencies are common among older adults. We hypothesized that low serum micronutrient concentrations were predictive of frailty among older disabled women living in the community...
- Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) studyMatteo Cesari
Sticht Center on Aging, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
Am J Clin Nutr 79:289-94. 2004..Muscle strength and physical performance in old age might be related to the oxidative damage caused by free radicals...
- Low serum carotenoids and development of severe walking disability among older women living in the community: the women's health and aging study IRichard D Semba
The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Age Ageing 36:62-7. 2007..to determine whether low serum carotenoid levels, an indicator of low intake of fruits and vegetables, are associated with the progression of disability in older women...
- A randomized, controlled trial of disability prevention in frail older patients screened in primary care: the FRASI study. Design and baseline evaluationStefania Bandinelli
Geriatric Rehabilitation Unit, ASF, Tuscany Regional Health Agency, and Laboratory of Clinical Epidemiology, Italian National Institute of Research and Care of Aging, Firenze, Italy
Aging Clin Exp Res 18:359-66. 2006..We describe the enrollment and intervention phases of FRASI (FRAilty, Screening and Intervention), a randomized controlled trial aimed at preventing ADL disability in frail older persons screened in primary care...
- Association between vitamin D status and physical performance: the InCHIANTI studyDenise K Houston
Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Gerontol A Biol Sci Med Sci 62:440-6. 2007..Vitamin D status has been hypothesized to play a role in musculoskeletal function. Using data from the InCHIANTI study, we examined the association between vitamin D status and physical performance...
- Low plasma N-3 fatty acids and dementia in older persons: the InCHIANTI studyAntonio Cherubini
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy
J Gerontol A Biol Sci Med Sci 62:1120-6. 2007..N-3 fatty acids (FA) have an important role in brain development and function. However, there is conflicting evidence concerning the relationship between n-3 FA and dementia in older persons...
- Epidemiology of back pain in a representative cohort of Italian persons 65 years of age and older: the InCHIANTI studyFrancesca Cecchi
Fondazione Don Carlo Gnocchi, Institute for Recovery and Care with Scientific Character, Centro S Maria agli Ulivi, Florence, Italy
Spine (Phila Pa 1976) 31:1149-55. 2006..Clinico-epidemiologic study in the Chianti area (Tuscany, Italy)...
- Lower plasma vitamin E levels are associated with the frailty syndrome: the InCHIANTI studyAlessandro Ble
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21225, USA
J Gerontol A Biol Sci Med Sci 61:278-83. 2006....
- Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markersLuigi Ferrucci
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Harbor Hospital, 5th Floor, 3001 Hanover Street, Baltimore, MD 21225, USA
J Clin Endocrinol Metab 91:439-46. 2006..The protective effect of PUFAs is mediated by multiple mechanisms, including their antiinflammatory properties. The association of physiological PUFA levels with pro- and antiinflammatory markers has not been established...
- Anemia is associated with depression in older adults: results from the InCHIANTI studyGraziano Onder
Geriatric Department, Catholic University of the Sacred Heart, Rome, Italy
J Gerontol A Biol Sci Med Sci 60:1168-72. 2005..The objective of this study was to examine whether depressive symptoms and anemia are associated among older adults living in the community...
- Axonal degeneration affects muscle density in older men and womenFulvio Lauretani
Laboratory of Clinical Epidemiology, Italian National Institute of Research and Care on Aging INRCA, Geriatric Department, Florence, Italy Tuscany Regional Health Agency, Florence, Italy
Neurobiol Aging 27:1145-54. 2006..These findings suggest that intrinsic changes in the muscle tissue are partially caused by a reduction in the number of motor axons...
- Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI studyRoberto Elosua
Nutrition and Genomics Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts, USA
J Gerontol A Biol Sci Med Sci 60:760-7. 2005..Our aim was to determine the association between physical activity and physical performance, and inflammatory biomarkers in elderly persons...
- Changes in anthropometric measures in men and women across the life-span: findings from the InCHIANTI studyBenedetta Bartali
Laboratory of Clinical Epidemiology, INRCA Geriatric Department, Florence
Soz Praventivmed 47:336-48. 2002..To describe the age distribution of anthropometric parameters in a population-based sample of older persons...
- The frailty syndrome: a critical issue in geriatric oncologyLuigi Ferrucci
Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA
Crit Rev Oncol Hematol 46:127-37. 2003..Improvements in the definition of the frailty syndrome may profit from the clinical experience of oncologists...
- Age and disability affect dietary intakeBenedetta Bartali
Laboratory of Clinical Epidemiology, Geriatric Department, National Institute of Research and Care on Aging INRCA, Florence, Italy
J Nutr 133:2868-73. 2003....
- Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopeniaFulvio Lauretani
Geriatric Department, Italian National Insitute of Research and Care on Aging, Florence, Italy
J Appl Physiol 95:1851-60. 2003..The findings of the study lay the basis for a cost-effective, clinical marker of sarcopenia based on a measure of isometric handgrip strength. Our findings should be verified in a longitudinal study...
- Dietary intake estimated using different methods in two Italian older populationsBenedetta Bartali
Geriatric Department, Laboratory of Clinical Epidemiology, National Institute of Research and Care on Aging INRCA, Viale Michelangiolo no 41, 50125 Florence, Italy
Arch Gerontol Geriatr 38:51-60. 2004..Future study should attempt to generalize these findings at an individual level by collecting data with both instruments in the same subjects...
- Neurological examination findings to predict limitations in mobility and falls in older persons without a history of neurological diseaseLuigi Ferrucci
Longitudinal Studies Section, Clinical Research Branch, National Instituts on Aging, National Institute of Health, Baltimore, Maryland 21225, USA
Am J Med 116:807-15. 2004..To estimate the prevalence of neurological signs and their association with limitations in mobility and falls in a sample of older persons without known neurological disease...
- Bone density and hemoglobin levels in older persons: results from the InCHIANTI studyMatteo Cesari
Sticht Center on Aging, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina, NC 27157, USA
Osteoporos Int 16:691-9. 2005..The bone loss associated with hemoglobin levels mainly occurs in the cortical bone. Women with lower hemoglobin levels demonstrate a higher bone loss than male counterparts...
- The origins of age-related proinflammatory stateLuigi Ferrucci
Intramural Research Program, National Institute on Aging, Longitudinal Studies Section, Clinical Research Branch, ASTRA Unit, Harbor Hospital 5th Floor, 3001 S Hanover St, Baltimore, MD, USA
Blood 105:2294-9. 2005..Part of the "proinflammatory state" in older persons is related to the high prevalence of cardiovascular risk factor and morbidity...
- Executive function correlates with walking speed in older persons: the InCHIANTI studyAlesandro Ble
Longitudinal Studies Section, Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland
J Am Geriatr Soc 53:410-5. 2005..To study the association between performance on psychological tests of executive function and performance on lower extremity tasks with different attentional demands in a large sample of nondemented, older adults...
- Vitamin E levels, cognitive impairment and dementia in older persons: the InCHIANTI studyAntonio Cherubini
Institute of Gerontology and Geriatrics, University of Perugia Medical School, Department of Clinical and Experimental Medicine, Via Brunamonti, Policlinico Monteluce, Padiglione E, Perugia 06122, Italy
Neurobiol Aging 26:987-94. 2005..This study supports the notion that higher vitamin E plasma levels might provide significant protection against cognitive impairment and dementia in elderly subjects...
- Urinary calcium is a determinant of bone mineral density in elderly men participating in the InCHIANTI studyGiuseppe Vezzoli
Division of Nephrology Dialysis and Hypertension, IRCCS San Raffaele Hospital, Postgraduate School of Nephrology, Vita Salute University, Milan, Italy
Kidney Int 67:2006-14. 2005....
- Understanding the physiological and functional consequences of menopause: the PROSALMEN study. PROgetto SALute MENopausaStefania Bandinelli
INRCA Geriatric Department, Firenze, Italy
Aging Clin Exp Res 14:170-7. 2002....