N Altorki

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer
    N K Altorki
    Department of Cardiothoracic Surgery, Strang Cancer Prevention Center and Weill Medical College of Cornell University, New York, NY 10021, USA
    J Clin Oncol 21:2645-50. 2003
  2. pmc Three-field lymph node dissection for squamous cell and adenocarcinoma of the esophagus
    Nasser Altorki
    Division of General Thoracic Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
    Ann Surg 236:177-83. 2002
  3. doi request reprint Phase II proof-of-concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer
    Nasser Altorki
    Weill Medical College, Cornell University, 525 East 68th St, New York, NY 10021, USA
    J Clin Oncol 28:3131-7. 2010
  4. doi request reprint Total number of resected lymph nodes predicts survival in esophageal cancer
    Nasser K Altorki
    Division of Thoracic Surgery, New York Presbyterian Hospital and Weill Cornell Medical College, New York, New York 10021, USA
    Ann Surg 248:221-6. 2008
  5. doi request reprint Multifocal neoplasia and nodal metastases in T1 esophageal carcinoma: implications for endoscopic treatment
    Nasser K Altorki
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
    Ann Surg 247:434-9. 2008
  6. pmc Should en bloc esophagectomy be the standard of care for esophageal carcinoma?
    N Altorki
    Weill Medical College of Cornell University, Department of Cardiothoracic Surgery, New York, New York 10021, USA
    Ann Surg 234:581-7. 2001
  7. ncbi request reprint En-bloc esophagectomy--the three-field dissection
    Nasser Altorki
    Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
    Surg Clin North Am 85:611-9, xi. 2005
  8. ncbi request reprint Cyclooxygenase-2: a target for the prevention and treatment of cancers of the upper digestive tract
    Nasser K Altorki
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, Stang Cancer Prevention Center, New York, N Y, USA
    Prog Exp Tumor Res 37:107-23. 2003
  9. ncbi request reprint COX-2: a target for prevention and treatment of esophageal cancer
    Nasser Altorki
    Weill Medical College of Cornell University, New York, New York 10021, USA
    J Surg Res 117:114-20. 2004
  10. ncbi request reprint Bronchioloalveolar carcinoma and ground glass opacities
    Nasser K Altorki
    Department of Cardiothoracic Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 80:1560-1. 2005

Detail Information

Publications78

  1. ncbi request reprint Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer
    N K Altorki
    Department of Cardiothoracic Surgery, Strang Cancer Prevention Center and Weill Medical College of Cornell University, New York, NY 10021, USA
    J Clin Oncol 21:2645-50. 2003
    ..End points were toxicity, response rates, and measurement of intratumoral levels of prostaglandin E2 (PGE2)...
  2. pmc Three-field lymph node dissection for squamous cell and adenocarcinoma of the esophagus
    Nasser Altorki
    Division of General Thoracic Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
    Ann Surg 236:177-83. 2002
    ....
  3. doi request reprint Phase II proof-of-concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer
    Nasser Altorki
    Weill Medical College, Cornell University, 525 East 68th St, New York, NY 10021, USA
    J Clin Oncol 28:3131-7. 2010
    ..This proof-of-concept study examined safety and efficacy of short-term, preoperative pazopanib monotherapy in patients with operable stage I/II NSCLC...
  4. doi request reprint Total number of resected lymph nodes predicts survival in esophageal cancer
    Nasser K Altorki
    Division of Thoracic Surgery, New York Presbyterian Hospital and Weill Cornell Medical College, New York, New York 10021, USA
    Ann Surg 248:221-6. 2008
    ..In this retrospective study, the impact of total nodal count on overall survival in esophageal cancer was examined using a single institution surgical database...
  5. doi request reprint Multifocal neoplasia and nodal metastases in T1 esophageal carcinoma: implications for endoscopic treatment
    Nasser K Altorki
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
    Ann Surg 247:434-9. 2008
    ....
  6. pmc Should en bloc esophagectomy be the standard of care for esophageal carcinoma?
    N Altorki
    Weill Medical College of Cornell University, Department of Cardiothoracic Surgery, New York, New York 10021, USA
    Ann Surg 234:581-7. 2001
    ..To determine the impact of radical node dissection on the recurrence patterns and survival rates of patients with carcinoma of the esophagus...
  7. ncbi request reprint En-bloc esophagectomy--the three-field dissection
    Nasser Altorki
    Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
    Surg Clin North Am 85:611-9, xi. 2005
    ..This article examines the rationale,technique, and results of radical esophagectomy, including two-field and three-field lymph node dissection...
  8. ncbi request reprint Cyclooxygenase-2: a target for the prevention and treatment of cancers of the upper digestive tract
    Nasser K Altorki
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, Stang Cancer Prevention Center, New York, N Y, USA
    Prog Exp Tumor Res 37:107-23. 2003
  9. ncbi request reprint COX-2: a target for prevention and treatment of esophageal cancer
    Nasser Altorki
    Weill Medical College of Cornell University, New York, New York 10021, USA
    J Surg Res 117:114-20. 2004
  10. ncbi request reprint Bronchioloalveolar carcinoma and ground glass opacities
    Nasser K Altorki
    Department of Cardiothoracic Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 80:1560-1. 2005
  11. ncbi request reprint Bronchioloalveolar carcinoma in small pulmonary nodules: clinical relevance
    Nasser K Altorki
    Department of Cardio Thoracic Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Semin Thorac Cardiovasc Surg 17:123-7. 2005
    ..Only in this way will we be able to determine the clinical and molecular characteristics of these lesions and thus hopefully gain insight into their clinical relevance...
  12. ncbi request reprint Surgical resection for lung cancer in the octogenarian
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Suite M404, Weill Medical College of Cornell University, 525 E 68th St, New York, NY 10021, USA
    Chest 126:733-8. 2004
    ..As the US population ages, clinicians are increasingly confronted with octogenarians with resectable non-small cell lung cancer. Earlier reports documented substantial risk for surgical resection in this age group...
  13. doi request reprint Preoperative taxane-based chemotherapy and celecoxib for carcinoma of the esophagus and gastroesophageal junction: results of a phase 2 trial
    Nasser K Altorki
    Thoracic Surgery Division, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Cornell Medical College, New York City, New York 10021, USA
    J Thorac Oncol 6:1121-7. 2011
    ..The primary objective of this study was to determine the rate of pathological response after preoperative celecoxib and concurrent taxane-based chemotherapy in patients with cancer of the esophagus and gastroesophageal junction...
  14. pmc Monoclonal antibody MA454 reveals a heterogeneous expression pattern of MAGE-1 antigen in formalin-fixed paraffin embedded lung tumours
    A A Jungbluth
    Ludwig Institute for Cancer Research at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Br J Cancer 83:493-7. 2000
    ..The predominantly focal expression of MAGE-1 suggests that this antigen might not be sufficient as a sole target for immunotherapeutic approaches...
  15. ncbi request reprint Early lung cancer action project: initial findings on repeat screenings
    C I Henschke
    Weill Medical College of Cornell University, New York, New York, USA
    Cancer 92:153-9. 2001
    ..With the baseline results having been reported previously, the focus of the current study was on the early results of the repeat screenings...
  16. ncbi request reprint Preoperative chemotherapy for esophageal cancer with paclitaxel and carboplatin: results of a phase II trial
    R S Keresztes
    Weill Medical College of Cornell University, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 126:1603-8. 2003
    ..The objective of this study was to determine the efficacy of preoperative paclitaxel and carboplatin in patients with carcinoma of the esophagus...
  17. ncbi request reprint Early lung cancer action project: a summary of the findings on baseline screening
    C I Henschke
    Department of Radiology, New York Presbyterian Hospital-Weill Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA
    Oncologist 6:147-52. 2001
    ..CONCLUSION: Baseline CT screening for lung cancer provides for detecting the disease at earlier and presumably more commonly curable stages in a cost-effective manner...
  18. ncbi request reprint Detection of early-stage lung cancer: computed tomographic scan or chest radiograph?
    N Altorki
    Department of Cardiothoracic Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 121:1053-7. 2001
    ..In this study we compared the stage distribution of lung cancers detected by a computed tomographic scan with that of lung cancers detected by a routine chest x-ray film...
  19. ncbi request reprint Suppression of apoptosis does not foster neoplastic growth in Barrett's esophagus
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York City 10021, USA
    Mod Pathol 12:239-50. 1999
    ..These observations will lead to a better understanding of the pathogenesis of esophageal adenocarcinoma and might contribute to enhancing the diagnostic accuracy when presented with dysplastic lesions...
  20. ncbi request reprint Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer
    K Yoshimatsu
    Department of Medicine, Weill Medical College of Cornell University and Strang Cancer Prevention Center, New York, New York 10021, USA
    Clin Cancer Res 7:2669-74. 2001
    ..Consistent with prior observations for COX-2, these data suggest that both cellular transformation and cytokines contribute to the up-regulation of mPGES in NSCLC...
  21. ncbi request reprint mdm-2 expression correlates with wild-type p53 status in esophageal adenocarcinoma
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College, Cornell University, New York City 10021, USA
    Mod Pathol 12:580-6. 1999
    ..In cases without p53 mutation, overexpression of mdm-2 occurred in 50% of cases and might be responsible for stabilization of p53 protein and possible loss of tumor suppressor function...
  22. ncbi request reprint Inhibition of cyclooxygenase-2: an approach to preventing cancer of the upper aerodigestive tract
    A J Dannenberg
    Department of Medicine, New York Presbyterian Hospital and Weill Medical College of Cornell University, New York 10021, USA
    Ann N Y Acad Sci 952:109-15. 2001
    ..Importantly, clinical trials have been initiated to assess the chemopreventive properties of selective COX-2 inhibitors...
  23. ncbi request reprint Early Lung Cancer Action Project: overall design and findings from baseline screening
    C I Henschke
    Weill Medical College of Cornell University and New York Presbyterian Hospital, NY 10021, USA
    Lancet 354:99-105. 1999
    ..The Early Lung Cancer Action Project (ELCAP) is designed to evaluate baseline and annual repeat screening by low-radiation-dose computed tomography (low-dose CT) in people at high risk of lung cancer. We report the baseline experience...
  24. doi request reprint Surgical management of chylothorax
    S Paul
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital Weill Cornell Medical College, New York, New York 10065, United States
    Thorac Cardiovasc Surg 57:226-8. 2009
    ..However, the optimal treatment for traumatic patients is unclear. We wanted to examine the outcomes of patients with high output or recurrent chylothorax who were treated by surgical means...
  25. ncbi request reprint Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer
    A J Dannenberg
    Department of Medicine, Weill Medical College of Cornell University and Strang Cancer Prevention Center, New York, USA
    Lancet Oncol 2:544-51. 2001
    ..Importantly, selective COX 2 inhibitors appear to be safe enough in human beings to allow large-scale clinical testing in healthy people. Several chemoprevention trials using selective COX 2 inhibitors are underway...
  26. ncbi request reprint Early lung cancer action project: annual screening using single-slice helical CT
    C I Henschke
    Department of Radiology, Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann N Y Acad Sci 952:124-34. 2001
    ..A discussion follows of the meaning of the results and possible future screening protocols...
  27. ncbi request reprint Acidic fibroblast growth factor is expressed sequentially in the progression from Barrett's esophagus to esophageal adenocarcinoma
    R A Soslow
    Department of Pathology, New York Presbyterian Hospital Weill Medical College of Cornell University NYPH WMC, New York, NY 10021, USA
    Dis Esophagus 14:23-7. 2001
    ..The data also underscore the important role of fibroblast growth factors in tumorigenesis...
  28. ncbi request reprint Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene, CT9
    M J Scanlan
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York 10021, USA
    Cancer Lett 150:155-64. 2000
    ..The coexpression pattern of these antigens provides a foundation for developing a polyvalent lung cancer vaccine...
  29. ncbi request reprint Immunohistochemical analysis of NY-ESO-1 antigen expression in normal and malignant human tissues
    A A Jungbluth
    Ludwig Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Int J Cancer 92:856-60. 2001
    ..There is great variability in NY-ESO-1 expression in individual tumors, ranging from an infrequent homogeneous pattern of staining to highly heterogeneous antigen expression...
  30. ncbi request reprint Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids
    F Zhang
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Gastroenterology 121:1391-9. 2001
    ..CONCLUSIONS: Reflux of duodenal contents into the esophagus led to increased COX-2 expression and mucosal thickening. Bile acids are likely to contribute to these effects...
  31. pmc Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer
    A O Gure
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 97:4198-203. 2000
    ..Although paraneoplastic neurological syndromes have been associated with several SCLC antigens, neurological symptoms have not been observed in patients with anti-SOX or anti-ZIC2 antibodies...
  32. ncbi request reprint Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3
    A O Gure
    Ludwig Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer Res 58:1034-41. 1998
    ..Considering the high frequency of 3p21 alterations in lung cancer and the fact that the tumor suppressor gene or genes in this locus have not been identified, additional studies on the NY-LU-12 gene and its product are warranted...
  33. ncbi request reprint Tumor size is a determinant of stage distribution in t1 non-small cell lung cancer
    Douglas B Flieder
    Department of Pathology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Chest 128:2304-8. 2005
    ..The objective of this study was to evaluate the relationship between size and stage in patients with T1 (< or = 3.0 cm) non-small cell lung cancer (NSCLC)...
  34. ncbi request reprint Accuracy of surveillance computed tomography in detecting recurrent or new primary lung cancer in patients with completely resected lung cancer
    Robert J Korst
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 82:1009-15; discussion 1015. 2006
    ....
  35. ncbi request reprint Intrathoracic manifestations of cervical anastomotic leaks after transthoracic esophagectomy for carcinoma
    Robert J Korst
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 80:1185-90. 2005
    ..The purpose of this study was to determine the incidence and clinical significance of intrathoracic manifestations of cervical anastomotic leaks after transthoracic esophagectomy...
  36. ncbi request reprint Cost effectiveness of chest computed tomography after lung cancer resection: a decision analysis model
    Michael S Kent
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Weill Medical College, Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 80:1215-22; discussion 1222-3. 2005
    ..This study involves the creation of a decision analysis model to predict the cost effectiveness of postoperative surveillance CT...
  37. ncbi request reprint CT screening for lung cancer: prevalence and incidence of mediastinal masses
    Claudia I Henschke
    Weill Medical College of Cornell Univ, 525 E 68th St, New York, NY 10021, USA
    Radiology 239:586-90. 2006
    ..To determine the frequency and natural course of mediastinal masses in asymptomatic people at high risk for lung cancer who were undergoing computed tomographic (CT) screening...
  38. ncbi request reprint Positron emission tomographic scanning in the diagnosis and staging of non-small cell lung cancer 2 cm in size or less
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Cornell Medical Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 130:1611-5. 2005
    ..However, there are few data on the utility of positron emission tomography in the diagnosis of patients with tumors of 2 cm or less in size...
  39. ncbi request reprint Cancer-testis genes are coordinately expressed and are markers of poor outcome in non-small cell lung cancer
    Ali O Gure
    Ludwig Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 11:8055-62. 2005
    ..We asked whether cancer-testis gene expression occurred coordinately, and whether it correlated with variables of disease and clinical outcome of non-small cell lung cancer (NSCLC)...
  40. ncbi request reprint Downstaging of T or N predicts long-term survival after preoperative chemotherapy and radical resection for esophageal carcinoma
    Robert J Korst
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 82:480-4; discussion 484-5. 2006
    ....
  41. ncbi request reprint Randomized phase II trial of docetaxel/irinotecan and gemcitabine/irinotecan with or without celecoxib in the second-line treatment of non-small-cell lung cancer
    Rogerio Lilenbaum
    Mount Sinai Cancer Center, Miami Beach, FL 33140, USA
    J Clin Oncol 24:4825-32. 2006
    ..This multicenter, phase II, randomized trial investigated efficacy and safety of irinotecan and docetaxel and irinotecan and gemcitabine, with or without CBX, in second-line treatment of NSCLC...
  42. ncbi request reprint Surgical resection for multifocal (T4) non-small cell lung cancer: is the T4 designation valid?
    Jeffrey L Port
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York 10021, USA
    Ann Thorac Surg 83:397-400. 2007
    ..In this study, we sought to determine the impact of multifocal, intralobar non-small cell lung cancer (NSCLC) on patient survival and its potential relevance to stage designation...
  43. doi request reprint The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection
    Christian G Peyre
    Department of Surgery, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA
    Ann Surg 248:549-56. 2008
    ..Surveillance, Epidemiology and End Results (SEER) data indicate that number of lymph nodes removed impacts survival in gastric cancer. Our aim was to study this relationship in esophageal cancer...
  44. doi request reprint Carcinoid tumor nested within a bronchogenic cyst
    Elliot Servais
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 136:227-8. 2008
  45. doi request reprint Primary esophageal large T-cell lymphoma mimicking esophageal carcinoma: a case report and literature review
    Patrick L Wagner
    Department of Cardiothoracic Surgery, New York Presbyterian Hospital Weill Cornell Medical Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 135:957-8, 958.e1. 2008
  46. pmc Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming
    Djordje Atanackovic
    Department of Oncology Hematology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Proc Natl Acad Sci U S A 105:1650-5. 2008
    ..These data provide an immunological rationale for vaccine design in light of recently reported favorable clinical responses in NSCLC patients after vaccination with MAGE-A3 protein plus adjuvant AS02B...
  47. pmc PLAC1, a trophoblast-specific cell surface protein, is expressed in a range of human tumors and elicits spontaneous antibody responses
    Wilson A Silva
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Immun 7:18. 2007
    ..We found by ELISA that PLAC1 is immunogenic in a subset of cancer patients and healthy women. Its physical and expression characteristics render it a potential target for both active and passive cancer immunotherapeutic strategies...
  48. ncbi request reprint Positron emission tomographic scanning predicts survival after induction chemotherapy for esophageal carcinoma
    Jeffrey L Port
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 84:393-400; discussion 400. 2007
    ..This study assessed the predictive accuracy of clinical response (CR) and positron emission tomography (PET) scanning in determining pathological downstaging and disease free survival (DFS) after chemotherapy...
  49. ncbi request reprint The role of CT screening for lung cancer
    Claudia I Henschke
    Department of Radiology and Cardiothoracic Surgery, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
    Thorac Surg Clin 17:137-42. 2007
    ....
  50. ncbi request reprint Risk factors for occult mediastinal metastases in clinical stage I non-small cell lung cancer
    Paul C Lee
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 84:177-81. 2007
    ..The goal of this study was to analyze the risk factors for occult mediastinal metastases in this subset of patients...
  51. ncbi request reprint Giant cavernous hemangioma of the distal esophagus treated with esophagectomy
    Anthony W Kim
    Department Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, NY, USA
    J Thorac Cardiovasc Surg 133:1665-7. 2007
  52. ncbi request reprint Long-term survival and recurrence in patients with resected non-small cell lung cancer 1 cm or less in size
    Paul C Lee
    Department of Cardiothoracic Surgery, Weill Cornell Medical Center, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 132:1382-9. 2006
    ..We sought to examine the long-term survival and recurrence patterns after resection of these tumors...
  53. ncbi request reprint CT screening for lung cancer: past and ongoing studies
    Claudia I Henschke
    Department of Radiology, Weill Medical College of Cornell University, New York, New York 10021, USA
    Semin Thorac Cardiovasc Surg 17:99-106. 2005
    ....
  54. ncbi request reprint COX-2 inhibition in upper aerodigestive tract tumors
    Nasser K Altorki
    New York Presbyterian Medical Center, 525 East 168th Street, Box 110, New York, NY 10021, USA
    Semin Oncol 31:30-6. 2004
    ....
  55. ncbi request reprint Managing the small pulmonary nodule discovered by CT
    Daniel M Libby
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Weill Medical College of Cornell University, New York, NY, USA
    Chest 125:1522-9. 2004
    ..To review the Early Lung Cancer Action Project experience and the medical literature from 1993 to 2003 on detection of the small, noncalcified pulmonary nodule by CT in order to formulate a management algorithm for these nodules...
  56. ncbi request reprint Vaccine-induced CD4+ T cell responses to MAGE-3 protein in lung cancer patients
    Djordje Atanackovic
    Ludwig Institute for Cancer Research, and Department of Human Immunogenetics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Immunol 172:3289-96. 2004
    ..This development provides the framework for further evaluating integrated immune responses in vaccine settings and for optimizing these responses for clinical benefit...
  57. ncbi request reprint Benzo[a]pyrene phenols are more potent inducers of CYP1A1, CYP1B1 and COX-2 than benzo[a]pyrene glucuronides in cell lines derived from the human aerodigestive tract
    Taghreed Almahmeed
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Carcinogenesis 25:793-9. 2004
  58. ncbi request reprint Positron emission tomography scanning poorly predicts response to preoperative chemotherapy in non-small cell lung cancer
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Cornell Medical Center, New York, New York 10021, USA
    Ann Thorac Surg 77:254-9; discussion 259. 2004
    ..The purpose of this study was to examine the accuracy of positron emission tomography (PET) scanning in predicting the pathologic response to preoperative chemotherapy in the primary tumor and draining lymph nodes...
  59. ncbi request reprint Tumor size predicts survival within stage IA non-small cell lung cancer
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Cornell Medical Center, New York, NY 10021, USA
    Chest 124:1828-33. 2003
    ..The basic premise of CT screening is that size is an important determinant of survival in lung cancer. We sought to examine this hypothesis within stage IA non-small cell lung cancer (NSCLC)...
  60. ncbi request reprint Ruptured descending and thoracoabdominal aortic aneurysms
    Leonard N Girardi
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, New York, USA
    Ann Thorac Surg 74:1066-70. 2002
    ..However, in the setting of a ruptured thoracic aneurysm, one may not have the luxury of complex end-organ support. We analyzed our experience with ruptured thoracic aneurysms to define morbidity and mortality in the present era...
  61. ncbi request reprint Diagnosis and management of early lung cancer
    Bernard J Park
    Weill Medical College of Cornell University, New York, NY 10021, USA
    Surg Clin North Am 82:457-76, v. 2002
    ..Recent work on low-dose helical CT, however, has renewed interest in the challenge of detecting early-stage lung cancer...
  62. ncbi request reprint High grade dysplasia: surveillance, mucosal ablation, or resection?
    Robert J Korst
    Department of Cardiothoracic Surgery, The New York Hospital Cornell Medical Center, 525 East 68th Street, Room M 404, New York, New York 10021, USA
    World J Surg 27:1030-4. 2003
    ....
  63. ncbi request reprint Computerized tomographic nodule heterogeneity: present and future impact on indications for sublobar resections
    Harvey I Pass
    Department of Surgery and Oncology, Wayne State University and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Clin Lung Cancer 6:20-7. 2004
    ....
  64. ncbi request reprint Surgical resection for residual N2 disease after induction chemotherapy
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 79:1686-90. 2005
    ..In this study we analyzed our experience with resection after induction chemotherapy in patients with residual N2 disease to more precisely define the role of surgical resection in this group of patients...
  65. ncbi request reprint Surveillance computed tomography after complete resection for non-small cell lung cancer: results and costs
    Robert J Korst
    Division of Thoracic Surgery, Department of Cardiothoracic Sugery, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Thorac Cardiovasc Surg 129:652-60. 2005
    ..We also sought to determine whether resectable metachronous lung cancer can be detected with surveillance scans...
  66. ncbi request reprint Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer
    Nasser K Altorki
    Department of Cardiothoracic Surgery and Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
    Clin Cancer Res 11:4191-7. 2005
    ..To determine the effect of taxane-based chemotherapy on intratumoral levels of cyclooxygenase-2 (COX-2) and prostaglandin E(2) (PGE(2)) in patients with non-small cell lung cancer (NSCLC)...
  67. ncbi request reprint Imaging for esophageal tumors
    Robert J Korst
    Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Weill Medical College, Cornell University, 525 E 58th Street, New York, NY 10021, USA
    Thorac Surg Clin 14:61-9. 2004
    ..These findings need to be confirmed in larger studies. More sophisticated technology continues to be developed for imaging carcinoma of the esophagus, which will more than likely affect staging algorithms in the future...
  68. ncbi request reprint Current state of imaging for lung cancer staging
    Michael S Kent
    Department of Surgery, Weill Medical College, Cornell University, 525 East 68th Street, Suite K707, New York, NY 10021, USA
    Thorac Surg Clin 14:1-13. 2004
    ..Patients who have neurologic signs or symptoms should undergo a brain imaging study (CT or MRI). --Screening for extrathoracic disease is not necessary in asymptomatic patients who have clinical stage I or II disease...
  69. pmc CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients
    Sacha Gnjatic
    Ludwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 99:11813-8. 2002
    ....
  70. ncbi request reprint Tobacco smoke induces CYP1B1 in the aerodigestive tract
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, NY 10021, USA
    Carcinogenesis 25:2275-81. 2004
    ..05). Taken together, these results support a role for CYP1B1 in TS-induced carcinogenesis in the aerodigestive tract...
  71. ncbi request reprint Early lung cancer detection and treatment strategies
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Cornell Medical Center, New York Presbyterian Hospital, New York, NY 10021, USA
    Surg Oncol 11:191-9. 2002
    ..For the majority of these early stage patients, standard lobectomy is the treatment of choice. New options to potentially detect and treat early stage lung cancer will increase dramatically in the future...
  72. ncbi request reprint Risk of lung carcinoma among users of nonsteroidal antiinflammatory drugs
    Joshua E Muscat
    American Health Foundation, Valhalla, New York 10595, USA
    Cancer 97:1732-6. 2003
    ..To the authors' knowledge there are little data regarding whether regular use of NSAIDs reduces the risk of developing lung carcinoma in humans...
  73. ncbi request reprint Thoracic esophageal perforations: a decade of experience
    Jeffrey L Port
    Department of Cardiothoracic Surgery, Weill Cornell Medical Center, New York, New York 10021, USA
    Ann Thorac Surg 75:1071-4. 2003
    ..We reviewed our experience with esophageal perforations to determine the overall mortality and whether the time to presentation should influence management strategy...
  74. ncbi request reprint Resection of a symptomatic pericardial cyst using the computer-enhanced da Vinci Surgical System
    Matthew D Bacchetta
    Department of Cardiothoracic Surgery, the New York Presbyterian Hospital Weill Cornell Medical Center, New York, New York 10021, USA
    Ann Thorac Surg 75:1953-5. 2003
    ..He underwent successful resection using a computer-enhanced robotic surgical system. This case is an example of the continued extension of robotic-assisted thoracic surgery...
  75. pmc Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses
    Sacha Gnjatic
    Ludwig Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 100:8862-7. 2003
    ....
  76. ncbi request reprint Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands
    Dimitrios Moraitis
    Head and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY 10021, USA
    Cancer Res 65:664-70. 2005
    ..Moreover, these findings strengthen the rationale for determining whether inhibitors of COX-2 or EGFR tyrosine kinase activity can reduce the risk of tobacco smoke-related malignancies of the aerodigestive tract...
  77. ncbi request reprint A simple solution for management of the postpneumonectomy empyema cavity
    Michael S Kent
    Department of Cardiothoracic Surgery, Weill Medical College of Cornell University, New York, New York 10021, USA
    Ann Thorac Surg 78:1107-8. 2004
    ..My colleagues and I describe a simple approach for the definitive management of the open pleural space involving split-thickness skin grafts to marsupialize the pleural cavity...
  78. ncbi request reprint Proliferative myositis: a rare pseudosarcoma of the chest wall
    Michael S Kent
    Department of Cardiothoracic Surgery, The New York Presbyterian Hospital, Weill Cornell Medical Center, New York 10021, USA
    Ann Thorac Surg 73:1296-8. 2002
    ..Typically, the lesion presents in the extremities or the head and neck. We present an unusual case of proliferative myositis with involvement of the anterior chest wall...