Research Topics
| R Phillip DellingerSummaryAffiliation: Cooper University Hospital Country: USA Publications
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Detail Information
Publications
Ethics roundtable: Using new, expensive drugsRichard Burrows
Intensive Care Unit, Addington Hospital, Durban, South Africa
Crit Care 6:473-8. 2002
The International Sepsis Forum's controversies in sepsis: my initial vasopressor agent in septic shock is norepinephrine rather than dopamineVinay K Sharma
Critical Care Section, Cooper Health System, Camden, New Jersey, USA
Crit Care 7:3-5. 2003
Sepsis change bundles: converting guidelines into meaningful change in behavior and clinical outcomeMitchell M Levy
Medical Intensive Care Unit Rhode Island Hospital Providence, RI, USA
Crit Care Med 32:S595-7. 2004
Inclusion criteria for clinical trials in sepsis: did the American College of Chest Physicians/Society of Critical Care Medicine consensus conference definitions of sepsis have an impact?Stephen Trzeciak
Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
Chest 127:242-5. 2005..To promote uniformity in inclusion criteria for patient enrollment, the American College of Chest Physicians and Society of Critical Care Medicine first published consensus conference definitions for sepsis in 1992...
Positive clinical impact of low tidal volume strategyR Phillip Dellinger
Crit Care Med 33:1143-4. 2005
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012R Phillip Dellinger
Cooper University Hospital, Camden, New Jersey, USA
Crit Care Med 41:580-637. 2013..To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008...
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012R P Dellinger
Cooper University Hospital, Camden, NJ, USA
Intensive Care Med 39:165-228. 2013..To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008...
Association between inhaled nitric oxide treatment and long-term pulmonary function in survivors of acute respiratory distress syndromeR Phillip Dellinger
Division of Critical Care Medicine, Department of Medicine, Cooper University Hospital, 1 Cooper Plaza, Camden, NJ 08103, USA
Crit Care 16:R36. 2012..This analysis examined potential effects of iNO or placebo on pulmonary function six months post-treatment in ARDS survivors from that original study...
Arterial pressure optimization in the treatment of septic shock: a complex puzzleAlan E Jones
Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC 28203, USA
Crit Care 14:102. 2010..Although these data add important new evidence to our understanding of arterial pressure management, there are still many unanswered questions upon which future investigations should focus...
Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational studyFrank Bloos
Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany
Crit Care 15:R88. 2011..The intent of this study was to determine whether serum procalcitonin (PCT) levels are associated with prognosis, measured as organ dysfunctions and 28-day mortality, in patients with severe pneumonia...
Multicenter clinical trials in sepsis: understanding the big picture and building a successful operation at your hospitalR Phillip Dellinger
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, USA
Crit Care Nurs Clin North Am 23:215-25. 2011..The most professional satisfaction comes from the knowledge of contributing to original science in the field of the sepsis...
The Surviving Sepsis Campaign sepsis change bundles and clinical practiceR Phillip Dellinger
Section of Critical Care Medicine, Cooper University Hospital, Robert Wood Johnson Medical School, Camden, New Jersey, USA
Crit Care 9:653-4. 2005..The next step will be to demonstrate that the use of education and feedback for performance improvement will increase compliance and decrease mortality in the patient population in general...
Regional distribution of acoustic-based lung vibration as a function of mechanical ventilation modeR Phillip Dellinger
Division of Cardiovascular Disease and Critical Care Medicine, Robert Wood Johnson School of Medicine, University of Medicine and Dentistry of New Jersey, Cooper University Hospital, Camden, NJ 08103, USA
Crit Care 11:R26. 2007..In this study, we objectively evaluated the differences in regional lung vibration during different modes of mechanical ventilation by means of this new technology...
Multicenter clinical trials in sepsis: understanding the big picture and building a successful operation at your hospitalR Phillip Dellinger
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Division of Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
Crit Care Clin 25:869-79, xi. 2009..Because early enrollment into sepsis clinical trials is usually required, collaboration between emergency medicine and critical care is needed...
Recombinant activated protein C: the key is clinical assessment of risk of death, not subset analysisR Phillip Dellinger
Section of Critical Care Medicine, Cooper University Hospital, One Cooper Plaza, Camden, NJ 08103, USA
Crit Care 10:114. 2006..Additional studies of recombinant activated protein C (rhAPC) have added to our understanding about this drug and to controversy as well. So how do we deal with rhAPC use in our clinical practice?..
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008R Phillip Dellinger
Cooper University Hospital, One Cooper Plaza, 393 Dorrance, Camden 08103, NJ, USA
Intensive Care Med 34:17-60. 2008..To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock," published in 2004...
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008R Phillip Dellinger
Cooper University Hospital, Camden, NJ, USA
Crit Care Med 36:296-327. 2008..To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," published in 2004...
Efficacy and safety of a phospholipid emulsion (GR270773) in Gram-negative severe sepsis: results of a phase II multicenter, randomized, placebo-controlled, dose-finding clinical trialR Phillip Dellinger
Cooper University Hospital and University Medicine Dentistry New Jersey PD, Camden, NJ, USA
Crit Care Med 37:2929-38. 2009..Endotoxin neutralization correlates with the amount of phospholipid in the lipoprotein particles...
Important issues in the design and reporting of clinical trials in severe sepsis and acute lung injuryR Phillip Dellinger
Cooper University Hospital, Robert Wood Johnson Medical School, Camden, NJ, USA
J Crit Care 23:493-9. 2008..This article reviews many of the problems encountered in clinical trial design and reporting and offers a perspective on dealing with them to the betterment of a clinical trial...
Inflammation and coagulation: implications for the septic patientR Phillip Dellinger
Critical Care Section, of Cardiovascular Diseases and Critical Care Medicine, Cooper Health System, Camden, New Jersey 08103, USA
Clin Infect Dis 36:1259-65. 2003..The pathophysiological and clinical significance of this evidence and the relationship of coagulation to inflammation are discussed, as are positive and negative results of clinical trials of antithrombotic therapy...
Cardiovascular management of septic shockR Phillip Dellinger
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Section of Critical Care Medicine, Cooper Health System, Camden 08103, USA
Crit Care Med 31:946-55. 2003
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shockR Phillip Dellinger
Section of Critical Care Medicine, Cooper University Hospital, One Cooper Plaza, 393 Dorrance, Camden, NJ 08103, USA
Intensive Care Med 30:536-55. 2004..The impact of these guidelines will be formally tested and guidelines updated annually, and even more rapidly when some important new knowledge becomes available...
A prospective multicenter cohort study of the association between global tissue hypoxia and coagulation abnormalities during early sepsis resuscitationStephen Trzeciak
Department of Medicine, Division of Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
Crit Care Med 38:1092-100. 2010..We aimed to test the hypothesis that the quantity of exposure to global tissue hypoxia is associated with the degree of coagulation activation during early sepsis resuscitation...
Location of patients before transfer to a tertiary care intensive care unit: impact on outcomeDavid R Gerber
Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
J Crit Care 24:108-13. 2009..To evaluate the impact of the source of patients transferred to a tertiary care intensive care unit (ICU) (referring hospital ICU vs referring hospital emergency department [ED]) on outcomes of transferred patients...
Relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrestJ Hope Kilgannon
Department of Emergency Medicine, Cooper University Hospital, Camden, NJ 08103, USA
Circulation 123:2717-22. 2011..We aimed to define the relationship between supranormal oxygen tension and outcome in postresuscitation patients...
Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency departmentStephen Trzeciak
Division of Cardiovascular Disease and Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza, D363, Camden, NJ 08103, USA
Chest 129:225-32. 2006..We aimed to determine if EGDT end points could reliably be achieved in real-world clinical practice...
Transfusion of packed red blood cells is not associated with improved central venous oxygen saturation or organ function in patients with septic shockBrian M Fuller
Department of Anesthesiology, Division of Critical Care Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Emerg Med 43:593-8. 2012..The exact role of packed red blood cell (PRBC) transfusion in the setting of early resuscitation in septic shock is unknown...
Discordance between microcirculatory alterations and arterial pressure in patients with hemodynamic instabilityRyan C Arnold
Department of Emergency Medicine, Division of Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
J Crit Care 27:531.e1-7. 2012..We selected cardiopulmonary bypass (CPB) patients with expected and rapidly reversible hemodynamic instability to test the hypothesis that microcirculatory alterations can occur independent of mean arterial pressure (MAP)...
Ventricular dilation is associated with improved cardiovascular performance and survival in sepsisSergio L Zanotti Cavazzoni
Division of Critical Care Medicine, Cooper University Hospital, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Camden, NJ 08103, USA
Chest 138:848-55. 2010..The goal of this study was to evaluate the impact of myocardial dysfunction and changes in LV diameter on hemodynamics and survival in a murine model of sepsis...
Endotoxin removal: how far from the evidence? From EUPHAS to EUPHRATESJean Sebastien Rachoin
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Department of Medicine, Division of Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
Contrib Nephrol 167:111-8. 2010....
Serum lactate as a predictor of mortality in patients with infectionStephen Trzeciak
UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Division of Cardiovascular Disease and Critical Care Medicine, One Cooper Plaza, Camden 08103, NJ, USA
Intensive Care Med 33:970-7. 2007..To determine the utility of an initial serum lactate measurement for identifying high risk of death in patients with infection...
Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive techniqueJonathan V McCoy
Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
Resuscitation 80:893-7. 2009..However, pulmonary artery catheters (PAC) pose logistic challenges in acute care settings. We hypothesized that CCI measured with a calibrated minimally invasive technique (LiDCO/PulseCO, UK) would have good agreement with the PAC...
Assessment of asymmetric lung disease in intensive care unit patients using vibration response imagingSmith Jean
Department of Medicine, Robert Wood Johnson School of Medicine, University of Medicine and Dentistry of New Jersey, Cooper University Hospital, Camden, NJ 08103, USA
Anesth Analg 107:1243-7. 2008..The filtered output signal frequencies are presented as a gray-scale coded dynamic image, consisting of a series of 0.17 s frames, and as a table featuring the percentage contribution of each lung to the total vibration signal...
Hemodynamic optimization of sepsis-induced tissue hypoperfusionSergio L Zanotti Cavazzoni
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Camden, New Jersey, USA
Crit Care 10:S2. 2006..This review will cover the most important aspects of hemodynamic optimization for treatment of sepsis induced tissue-hypoperfusion...
Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility studyJ Hope Kilgannon
Department of Emergency Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, NJ, USA
Acad Emerg Med 15:499-505. 2008..We hypothesized that using a standardized order set, clinicians could achieve HT target temperature in routine practice with equal or better efficiency than that observed in randomized trials...
Case report: vibration response imaging findings following inadvertent esophageal intubationIsmail Cinel
Department of Medicine, Division of Critical Care Medicine, Robert Wood Johnson School of Medicine, University of Medicine and Dentistry of New Jersey, Cooper University Hospital, Camden, New Jersey, USA
Can J Anaesth 55:172-6. 2008..We describe the effect that inadvertent esophageal intubation has on the images and on the vibration distribution of vibration response imaging (VRI)...
Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortalityJ Hope Kilgannon
Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza, 114 Kelemen, Camden, NJ 08103, USA
Resuscitation 79:410-6. 2008..We tested the hypothesis that exposure to arterial hypotension after ROSC occurs commonly (>50%) and is an independent predictor of death...
Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsisRyan C Arnold
Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, New Jersey 08103, USA
Shock 32:35-9. 2009..These data provide rationale for a clinical trial of lactate clearance as a distinct end point of early sepsis resuscitation...
Impact of delayed transfer of critically ill patients from the emergency department to the intensive care unitDonald B Chalfin
Division of Critical Care Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA
Crit Care Med 35:1477-83. 2007..We aimed to determine the association between emergency department "boarding" (holding admitted patients in the emergency department pending intensive care unit transfer) and outcomes for critically ill patients...
Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsisSergio L Zanotti-Cavazzoni
Division of Critical Care Medicine, Cooper University Hospital, Dorrance 360, Once Cooper Plaza, Camden, NJ 08103, USA
Intensive Care Med 35:748-54. 2009..Current murine models of sepsis do not account for the effects of aggressive fluid resuscitation on hemodynamics and mortality...
Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survivalStephen Trzeciak
Division of Cardiovascular Disease and Critical Care Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
Ann Emerg Med 49:88-98, 98.e1-2. 2007....
Advances in pathogenesis and management of sepsisIsmail Cinel
Robert Wood Johnson School of Medicine, University of Medicine and Dentistry of New Jersey, Department of Critical Care Medicine, Cooper University Hospital, Camden, New Jersey, USA
Curr Opin Infect Dis 20:345-52. 2007..The rationale for therapeutic targets in sepsis has arisen from the concept of pathogenesis. This review focuses on recent advances in pathogenesis of sepsis that can aid in management of sepsis patients...
A phase 2 randomized, double-blind, placebo-controlled study of the safety and efficacy of talactoferrin in patients with severe sepsisKalpalatha Guntupalli
Department of Medicine, Baylor College of Medicine, Ben Taub General, Hospital Houston, TX, USA
Crit Care Med 41:706-16. 2013..Our objective was to determine if talactoferrin could reduce 28-day all-cause mortality in patients with severe sepsis and to assess its safety...
The association of prior statin use in septic shock treated with early goal directed therapyBrian M Fuller
Department of Anesthesiology, Division of Critical Care Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
Eur J Emerg Med 19:226-30. 2012..Previous literature suggests statins may have a therapeutic role in sepsis. No data have examined if statin use may have a positive impact beyond that afforded by early goal directed therapy (EGDT)...
Other supportive therapies in sepsis: an evidence-based reviewStephen Trzeciak
UMDNJ-Robert Wood Johnson Medical School at Camden, Camden, NJ, USA
Crit Care Med 32:S571-7. 2004..Proton pump inhibitors have not been assessed in a direct comparison with histamine-2 receptor antagonists but do demonstrate equivalency and ability to increase gastric pH...
Guidelines for severe infections: are they useful?Ismail Cinel
Robert Wood Johnson School of Medicine, University of Medicine and Dentistry of New Jersey, Section of Critical Care Medicine, Cooper University Hospital, Camden, New Jersey 08103, USA
Curr Opin Crit Care 12:483-8. 2006..The evolution of guidelines and their impact on delivery of care in severe infection is reviewed...
TAKEDA-143242 increased survival via reduced cytokines in porcine peritonitisRoy D Goldfarb
Department of Medicine, Sections of Cardiology and Critical Care, Rush Medical College, Chicago, Illinois, USA
J Surg Res 166:e165-73. 2011..This study found that pretreatment with TAK-242 yielded significantly positive survival benefit in a lethal sepsis model that was associated with improved cardiovascular status and suppressed cytokine release...
Controversies in sepsis clinical trials: proceedings of a meeting of the International Sepsis Forum, Lausanne, Switzerland, September 29, 2001R Phillip Dellinger
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08854, USA
J Crit Care 21:38-47. 2006..Once a therapy is approved, adopting less stringent but still appropriate criteria for the use of that therapy in clinical practice may be appropriate...
Drotrecogin alfa (activated) in an infant with gram-negative septic shockImran Sajan
Department of Pediatrics, Division of Pediatric Critical Care Medicine, Cooper Hospital University Medical Center, Camden, NJ 08103, USA
J Intensive Care Med 19:51-5. 2004..The authors believe that drotrecogin alfa (activated) should be considered in select children with life-threatening severe sepsis...
Targeting endotoxin in the treatment of sepsisJean Sebastien Rachoin
Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
Subcell Biochem 53:323-38. 2010..Since both pre-clinical rationale and studies support the targeting of endotoxin to ameliorate the pro-inflammatory and pro-coagulation response of severe sepsis, this therapeutic intervention is being pursued...
Recombinant activated protein C: decisions for administrationR Phillip Dellinger
Section of Critical Care Medicine, Cooper University Hospital, Camden, NJ, USA
Crit Care Med 34:530-1. 2006
Targeting the lipopolysaccharides: still a matter of debate?Raquel Nahra
Division of Critical Care Medicine, Department of Internal Medicine, Cooper University Hospital, Camden, New Jersey, USA
Curr Opin Anaesthesiol 21:98-104. 2008....
Infections and severe sepsis in solid-organ transplant patients admitted from a university-based EDStephen Trzeciak
Department of Emergency Medicine, University of Illinois at Chicago, Chicago, IL, USA
Am J Emerg Med 22:530-3. 2004..7% of these patients had severe sepsis. The emergency physician must have a high index of suspicion for infections when evaluating organ transplant recipients...
The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapyBrian M Fuller
Department of Anesthesiology, Division of Critical Care Medicine, and the Division of Emergency Medicine, Washington University School of Medicine, St Louis, MO, USA
Indian J Crit Care Med 14:165-9. 2010..The optimal hemoglobin level and transfusion threshold in patients with septic shock treated with an early, goal oriented approach to resuscitation remains unknown...
The surviving sepsis guidelines: not another "groundhog day"R Phillip Dellinger
Cooper Health Systems, Critical Care Section, Camden, NJ, USA
Crit Care Med 32:1601-2. 2004
Dynamic visualization of lung sounds with a vibration response device: a case seriesR Phillip Dellinger
Division of Cardiovascular Disease and Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
Respiration 75:60-72. 2008..The field of computer-assisted mapping of lung sounds is constantly evolving and several devices have been developed in this field...
Care of critically ill surgical patients using the 80-hour Accreditation Council of Graduate Medical Education work-week guidelines: a survey of current strategiesChad R Gordon
Department of Surgery, Division of Trauma and Surgical Critical Care, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Cooper University Hospital, Camden 08103, USA
Am Surg 72:497-9. 2006..The overall outcome of these new strategies still needs to be assessed before any beneficial results can be demonstrated...
Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infantsShonola S Da-Silva
Pediatric Critical Care Medicine, The Children s Regional Hospital, Cooper University Medical Center, UMDNJ RWJ Medical School at Camden, New Jersey, USA
Crit Care 8:77-8. 2004..The recognition that AHRF is often the result of a multifactorial process makes it unlikely that one treatment modality will have a major beneficial effect on mortality and morbidity...
Critical care medicine as a distinct product line with substantial financial profitability: the role of business planningCarolyn E Bekes
Robert Wood Johnson Medical School, Camden, NJ, USA
Crit Care Med 32:1207-14. 2004..This plan provided a rational foundation for development of the operating and capital budgets for the health system...
Porcine models of severe sepsis: emphasis on porcine peritonitisRoy D Goldfarb
Robert Wood Johnson School of Medicine-South University of Medicine and Dentistry, Camden, NJ 08103, USA
Shock 24:75-81. 2005
Lactate as a hemodynamic marker in the critically illBrian M Fuller
Division of Critical Care, Department of Anesthesiology, Washington University in St Louis, St Louis, Missouri, USA
Curr Opin Crit Care 18:267-72. 2012..This review focuses on the use of lactate as a marker for risk stratification, lactate clearance as a hemodynamic endpoint, and its use compared to mixed venous oxygenation as a resuscitation goal...
Recent developments in the treatment of sepsisVinay K Sharma
Critical Care Section, Cooper Health System, 459 Kelleman, 1 Cooper Plaza, Camden, NJ 08103, USA
Expert Opin Investig Drugs 12:139-52. 2003..Attempts to reduce apoptosis have been a new focus in the treatment of sepsis. There have also been recent developments in supportive care suggesting a role for vasopressin and replacement corticosteroid therapy...
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shockR Phillip Dellinger
Crit Care Med 32:858-73. 2004..The impact of these guidelines will be formally tested and guidelines updated annually and even more rapidly as some important new knowledge becomes as available...
Treatment options for severe sepsis and septic shockVinay K Sharma
Medical Intensive Care Unit, The Graduate Hospital and Clinical Assistant Professor of Medicine, Drexel University College of Medicine, Pepper Pavilion, Suite 607, 1800 Lombard Street, Philadelphia, PA 19144, USA
Expert Rev Anti Infect Ther 4:395-403. 2006..There is also some evidence to suggest that tight glucose control may improve outcome in these patients...
The International Sepsis Forum's frontiers in sepsis: High cardiac output should not be maintained in severe sepsisVinay K Sharma
Pulmonary and Critical Care Division, Graduate Hospital, Philadelphia, Pennsylvania, USA
Crit Care 7:272-5. 2003
Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC studyJohn C Marshall
University Health Network, University of Toronto, Toronto, Ontario, Canada
J Infect Dis 190:527-34. 2004..Stepwise logistic regression analysis showed that elevated Acute Physiology and Chronic Health Evaluation II score, gram-negative infection, and emergency admission status were independent predictors of EA...
Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trialRobert W Taylor
Critical Care Medicine, St Louis University/St John's Mercy Medical Center, St Louis, MO, USA
JAMA 291:1603-9. 2004....
Inhaled nitric oxide: should it be used in acute respiratory distress syndrome?R Phillip Dellinger
Crit Care Med 34:3035-6. 2006
Severe sepsis in an emergency department: prevalence, rapid identification, and appropriate treatmentR Phillip Dellinger
Crit Care Med 35:2461-2. 2007
2008 update of international guidelines for the management of severe sepsis and septic shock: should we change our current clinical practice?Roman Z Jaeschke
Pol Arch Med Wewn 118:92-5. 2008
Steroid therapy of septic shock: the decision is in the eye of the beholderR Phillip Dellinger
Crit Care Med 36:1987-9. 2008
Critical care medicine training and certification for emergency physiciansDavid T Huang
Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA
Ann Emerg Med 46:217-23. 2005..We therefore propose that all accreditation bodies work cooperatively to create a route to critical care medicine certification for emergency physicians who complete a critical care fellowship...
Critical care medicine training and certification for emergency physiciansDavid T Huang
The CRISMA Laboratory (Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Crit Care Med 33:2104-9. 2005..We therefore propose that all accreditation bodies work cooperatively to create a route to CCM certification for emergency physicians who complete a critical care fellowship...
