Ryan C Arnold

Summary

Affiliation: Cooper University Hospital
Country: USA

Publications

  1. doi request reprint Discordance between microcirculatory alterations and arterial pressure in patients with hemodynamic instability
    Ryan C Arnold
    Department of Emergency Medicine, Division of Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
    J Crit Care 27:531.e1-7. 2012
  2. pmc The association of near-infrared spectroscopy-derived tissue oxygenation measurements with sepsis syndromes, organ dysfunction and mortality in emergency department patients with sepsis
    Nathan I Shapiro
    Department of Emergency Medicine and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Crit Care 15:R223. 2011
  3. doi request reprint Point-of-care assessment of microvascular blood flow in critically ill patients
    Ryan C Arnold
    Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza, Camden, NJ 08103, USA
    Intensive Care Med 35:1761-6. 2009
  4. ncbi request reprint Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis
    Ryan C Arnold
    Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, New Jersey 08103, USA
    Shock 32:35-9. 2009
  5. pmc Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis
    Stephen Trzeciak
    Department of Medicine, Divisions of Cardiovascular Disease and Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza D363, Camden, NJ 08103, USA
    Intensive Care Med 34:2210-7. 2008
  6. doi request reprint A prospective multicenter cohort study of the association between global tissue hypoxia and coagulation abnormalities during early sepsis resuscitation
    Stephen Trzeciak
    Department of Medicine, Division of Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
    Crit Care Med 38:1092-100. 2010
  7. pmc Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial
    Alan E Jones
    Department of Emergency Medicine, 1000 Blythe Blvd, Carolinas Medical Center, Charlotte, NC 28203, USA
    JAMA 303:739-46. 2010
  8. ncbi request reprint Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival
    Stephen Trzeciak
    Division of Cardiovascular Disease and Critical Care Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
    Ann Emerg Med 49:88-98, 98.e1-2. 2007
  9. pmc Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials
    Stephen Trzeciak
    Department of Emergency Medicine, Division of Critical Care Medicine, University of Medicine and Dentistry of New Jersey UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
    Acad Emerg Med 15:399-413. 2008
  10. ncbi request reprint Serum lactate as a predictor of mortality in patients with infection
    Stephen Trzeciak
    UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Division of Cardiovascular Disease and Critical Care Medicine, One Cooper Plaza, Camden 08103, NJ, USA
    Intensive Care Med 33:970-7. 2007

Detail Information

Publications14

  1. doi request reprint Discordance between microcirculatory alterations and arterial pressure in patients with hemodynamic instability
    Ryan C Arnold
    Department of Emergency Medicine, Division of Critical Care Medicine, Cooper University Hospital, Camden, NJ 08103, USA
    J Crit Care 27:531.e1-7. 2012
    ..We selected cardiopulmonary bypass (CPB) patients with expected and rapidly reversible hemodynamic instability to test the hypothesis that microcirculatory alterations can occur independent of mean arterial pressure (MAP)...
  2. pmc The association of near-infrared spectroscopy-derived tissue oxygenation measurements with sepsis syndromes, organ dysfunction and mortality in emergency department patients with sepsis
    Nathan I Shapiro
    Department of Emergency Medicine and Center for Vascular Biology Research, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Crit Care 15:R223. 2011
    ....
  3. doi request reprint Point-of-care assessment of microvascular blood flow in critically ill patients
    Ryan C Arnold
    Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza, Camden, NJ 08103, USA
    Intensive Care Med 35:1761-6. 2009
    ..We hypothesized that a real-time point-of-care (POC) determination of the microcirculatory flow index (MFI), an established metric for assessing microcirculatory perfusion, agrees well with the conventional off-line analysis...
  4. ncbi request reprint Multicenter study of early lactate clearance as a determinant of survival in patients with presumed sepsis
    Ryan C Arnold
    Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, New Jersey 08103, USA
    Shock 32:35-9. 2009
    ..These data provide rationale for a clinical trial of lactate clearance as a distinct end point of early sepsis resuscitation...
  5. pmc Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis
    Stephen Trzeciak
    Department of Medicine, Divisions of Cardiovascular Disease and Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, One Cooper Plaza D363, Camden, NJ 08103, USA
    Intensive Care Med 34:2210-7. 2008
    ..We hypothesized that changes in microcirculatory flow during resuscitation are associated with changes in organ failure over the first 24 h of sepsis therapy...
  6. doi request reprint A prospective multicenter cohort study of the association between global tissue hypoxia and coagulation abnormalities during early sepsis resuscitation
    Stephen Trzeciak
    Department of Medicine, Division of Critical Care Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
    Crit Care Med 38:1092-100. 2010
    ..We aimed to test the hypothesis that the quantity of exposure to global tissue hypoxia is associated with the degree of coagulation activation during early sepsis resuscitation...
  7. pmc Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial
    Alan E Jones
    Department of Emergency Medicine, 1000 Blythe Blvd, Carolinas Medical Center, Charlotte, NC 28203, USA
    JAMA 303:739-46. 2010
    ..Goal-directed resuscitation for severe sepsis and septic shock has been reported to reduce mortality when applied in the emergency department...
  8. ncbi request reprint Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival
    Stephen Trzeciak
    Division of Cardiovascular Disease and Critical Care Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
    Ann Emerg Med 49:88-98, 98.e1-2. 2007
    ....
  9. pmc Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials
    Stephen Trzeciak
    Department of Emergency Medicine, Division of Critical Care Medicine, University of Medicine and Dentistry of New Jersey UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ, USA
    Acad Emerg Med 15:399-413. 2008
    ..We also present the scientific rationale for clinical trials of exogenous NO administration to treat microcirculatory dysfunction and augment microcirculatory blood flow in early sepsis therapy...
  10. ncbi request reprint Serum lactate as a predictor of mortality in patients with infection
    Stephen Trzeciak
    UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Division of Cardiovascular Disease and Critical Care Medicine, One Cooper Plaza, Camden 08103, NJ, USA
    Intensive Care Med 33:970-7. 2007
    ..To determine the utility of an initial serum lactate measurement for identifying high risk of death in patients with infection...
  11. pmc Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol
    Michael A Puskarich
    Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC, USA
    Crit Care Med 39:2066-71. 2011
    ..We sought to determine the association between time to initial antibiotics and mortality of patients with septic shock treated with an emergency department-based early resuscitation protocol...
  12. doi request reprint Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique
    Jonathan V McCoy
    Department of Emergency Medicine, UMDNJ Robert Wood Johnson Medical School at Camden, Cooper University Hospital, Camden, NJ 08103, USA
    Resuscitation 80:893-7. 2009
    ..However, pulmonary artery catheters (PAC) pose logistic challenges in acute care settings. We hypothesized that CCI measured with a calibrated minimally invasive technique (LiDCO/PulseCO, UK) would have good agreement with the PAC...
  13. pmc Multicenter study of central venous oxygen saturation (ScvO(2)) as a predictor of mortality in patients with sepsis
    Jennifer V Pope
    Harvard Affiliated Emergency Medicine Residency, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Ann Emerg Med 55:40-46.e1. 2010
    ..Abnormal (both low and high) central venous saturation (ScvO(2)) is associated with increased mortality in emergency department (ED) patients with suspected sepsis...
  14. doi request reprint Multicenter observational study of the development of progressive organ dysfunction and therapeutic interventions in normotensive sepsis patients in the emergency department
    Ryan C Arnold
    Department of Emergency Medicine, Cooper University Hospital, Camden, NJ
    Acad Emerg Med 20:433-40. 2013
    ....