Francisco Sylvester

Summary

Affiliation: Connecticut Children's Medical Center
Country: USA

Publications

  1. doi request reprint Chronic pediatric inflammatory diseases: effects on bone
    Anuradha Viswanathan
    University of Connecticut School of Medicine, Farmington, CT, USA
    Rev Endocr Metab Disord 9:107-22. 2008
  2. doi request reprint Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis
    Francisco A Sylvester
    Division of Digestive Diseases, Hepatology and Nutrition, Connecticut Children s Medical Center, Hartford, Connecticut, USA
    Inflamm Bowel Dis 17:1726-30. 2011
  3. doi request reprint A two-year longitudinal study of persistent lean tissue deficits in children with Crohn's disease
    Francisco A Sylvester
    Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Clin Gastroenterol Hepatol 7:452-5. 2009
  4. ncbi request reprint IBD and skeletal health: children are not small adults!
    Francisco A Sylvester
    Division of Digestive Diseases and Nutrition, University of Connecticut School of Medicine, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Inflamm Bowel Dis 11:1020-3. 2005
  5. ncbi request reprint Are activated T cells regulators of bone metabolism in children with Crohn disease?
    Francisco A Sylvester
    Connecticut Children s Medical Center, Saint Francis Hospital and Medical Center, Hartford 06106, and University of Connecticut School of Medicine, Farmington, Connecticut, USA
    J Pediatr 148:461-6. 2006
  6. ncbi request reprint Natural history of bone metabolism and bone mineral density in children with inflammatory bowel disease
    Francisco A Sylvester
    Division of Gastroenterology and Nutrition, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Inflamm Bowel Dis 13:42-50. 2007
  7. pmc Skeletal health of children and adolescents with inflammatory bowel disease
    HELEN PAPPA
    Division of Gastroenterology and Nutrition, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr Gastroenterol Nutr 53:11-25. 2011
  8. ncbi request reprint Effect of Crohn's disease on bone metabolism in vitro: a role for interleukin-6
    Francisco A Sylvester
    Department of Pediatrics, Connecticut Children s Medical Center, University of Connecticut, Hartford 06106, USA
    J Bone Miner Res 17:695-702. 2002
  9. ncbi request reprint Effects of activated T cells on osteoclastogenesis depend on how they are activated
    Nancy Wyzga
    Connecticut Children s Medical Center, Hartford, CT, USA
    Bone 35:614-20. 2004
  10. ncbi request reprint Effects of serum from children with newly diagnosed Crohn disease on primary cultures of rat osteoblasts
    Samuel Varghese
    Department of Research, Saint Francis Hospital and Medical Center, Hartford, Connecticut, USA
    J Pediatr Gastroenterol Nutr 35:641-8. 2002

Research Grants

  1. Mechanisms of Bone Loss in Pediatric Crohn Disease
    Francisco Sylvester; Fiscal Year: 2007

Collaborators

Detail Information

Publications13

  1. doi request reprint Chronic pediatric inflammatory diseases: effects on bone
    Anuradha Viswanathan
    University of Connecticut School of Medicine, Farmington, CT, USA
    Rev Endocr Metab Disord 9:107-22. 2008
    ..In this paper we will provide an overview of the effects of chronic inflammatory conditions on bone mass in children. We will also present relevant data from adult patients, when pediatric data are scant or not available...
  2. doi request reprint Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis
    Francisco A Sylvester
    Division of Digestive Diseases, Hepatology and Nutrition, Connecticut Children s Medical Center, Hartford, Connecticut, USA
    Inflamm Bowel Dis 17:1726-30. 2011
    ..We aimed to determine whether fecal OPG predicts the need for second-line therapies in children hospitalized for UC...
  3. doi request reprint A two-year longitudinal study of persistent lean tissue deficits in children with Crohn's disease
    Francisco A Sylvester
    Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Clin Gastroenterol Hepatol 7:452-5. 2009
    ..We observed the effects of Crohn's disease on body composition and bone mineral content (BMC), beginning at diagnosis and followed prospectively for 2 years...
  4. ncbi request reprint IBD and skeletal health: children are not small adults!
    Francisco A Sylvester
    Division of Digestive Diseases and Nutrition, University of Connecticut School of Medicine, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Inflamm Bowel Dis 11:1020-3. 2005
    ..In this concise review, we aim to provide an update on this topic, with focus on how pediatric IBD affects bone health...
  5. ncbi request reprint Are activated T cells regulators of bone metabolism in children with Crohn disease?
    Francisco A Sylvester
    Connecticut Children s Medical Center, Saint Francis Hospital and Medical Center, Hartford 06106, and University of Connecticut School of Medicine, Farmington, Connecticut, USA
    J Pediatr 148:461-6. 2006
    ..To test the hypothesis that circulating activated T cells may release cytokines that decrease bone turnover in children with Crohn disease...
  6. ncbi request reprint Natural history of bone metabolism and bone mineral density in children with inflammatory bowel disease
    Francisco A Sylvester
    Division of Gastroenterology and Nutrition, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Inflamm Bowel Dis 13:42-50. 2007
    ..In children with inflammatory bowel disease (IBD) it is not known whether reductions in bone mineral density (BMD) are a consequence of bone turnover alterations and if BMD improves with treatment...
  7. pmc Skeletal health of children and adolescents with inflammatory bowel disease
    HELEN PAPPA
    Division of Gastroenterology and Nutrition, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr Gastroenterol Nutr 53:11-25. 2011
    ..Finally, we summarize the existing numerous gaps in knowledge and potential subjects for future research endeavors...
  8. ncbi request reprint Effect of Crohn's disease on bone metabolism in vitro: a role for interleukin-6
    Francisco A Sylvester
    Department of Pediatrics, Connecticut Children s Medical Center, University of Connecticut, Hartford 06106, USA
    J Bone Miner Res 17:695-702. 2002
    ..These results suggest that IL-6 is a mediator of the effects of Crohn's serum on in vitro mineralization and may be a contributing factor to the osteopenia associated with CD...
  9. ncbi request reprint Effects of activated T cells on osteoclastogenesis depend on how they are activated
    Nancy Wyzga
    Connecticut Children s Medical Center, Hartford, CT, USA
    Bone 35:614-20. 2004
    ..Both pro- and anti-resorptive properties have been described. We reasoned that this reported variability of the effects of T cells on osteoclast formation depends on how T cells are activated in vitro...
  10. ncbi request reprint Effects of serum from children with newly diagnosed Crohn disease on primary cultures of rat osteoblasts
    Samuel Varghese
    Department of Research, Saint Francis Hospital and Medical Center, Hartford, Connecticut, USA
    J Pediatr Gastroenterol Nutr 35:641-8. 2002
    ..We therefore examined the effects of serum from newly diagnosed, untreated children with CD on osteoblasts in culture and the role of interleukin-6 (IL-6), a cytokine present in excess in active CD that also has direct effects on bone...
  11. doi request reprint Hemophagocytic syndrome in an adolescent with Crohn disease receiving azathioprine and infliximab
    Karen A Francolla
    Medical College of Wisconsin, Children s Hospital of Wisconsin, Milwaukee, USA
    J Pediatr Gastroenterol Nutr 47:193-5. 2008
  12. ncbi request reprint Cracking the risk of fractures in Crohn disease
    Francisco A Sylvester
    University of Connecticut School of Medicine, USA
    J Pediatr Gastroenterol Nutr 38:113-4. 2004
  13. ncbi request reprint Do bones crack under the effects of inflammatory bowel disease in children?
    Francisco A Sylvester
    J Pediatr Gastroenterol Nutr 43:563-5. 2006

Research Grants5

  1. Mechanisms of Bone Loss in Pediatric Crohn Disease
    Francisco Sylvester; Fiscal Year: 2007
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