Christopher L Carroll

Summary

Affiliation: Connecticut Children's Medical Center
Country: USA

Publications

  1. doi request reprint Pediatric status asthmaticus
    Christopher L Carroll
    Division of Pediatric Critical Care, Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, CT 06106, USA
    Crit Care Clin 29:153-66. 2013
  2. doi request reprint Pulmonary mechanics following albuterol therapy in mechanically ventilated infants with bronchiolitis
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    J Asthma 49:688-96. 2012
  3. doi request reprint β2-adrenergic receptor haplotype linked to intubation and mechanical ventilation in children with asthma
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, CT 06106, USA
    J Asthma 49:563-8. 2012
  4. doi request reprint Beta-adrenergic receptor polymorphisms associated with length of ICU stay in pediatric status asthmaticus
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, Connecticut 06106, USA
    Pediatr Pulmonol 47:233-9. 2012
  5. doi request reprint Use of dexmedetomidine for sedation of children hospitalized in the intensive care unit
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    J Hosp Med 3:142-7. 2008
  6. doi request reprint Slow-responders to IV beta2-adrenergic agonist therapy: defining a novel phenotype in pediatric asthma
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Pediatr Pulmonol 43:627-33. 2008
  7. doi request reprint Beta2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations
    Christopher L Carroll
    Department of Pediatrics, Division of Pediatric Critical Care, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    Chest 135:1186-92. 2009
  8. ncbi request reprint Emergent endotracheal intubations in children: be careful if it's late when you intubate
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT, USA
    Pediatr Crit Care Med 11:343-8. 2010
  9. doi request reprint Identifying an at-risk population of children with recurrent near-fatal asthma exacerbations
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    J Asthma 47:460-4. 2010
  10. ncbi request reprint Childhood overweight increases hospital admission rates for asthma
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington St, Hartford, CT 06106, USA
    Pediatrics 120:734-40. 2007

Detail Information

Publications29

  1. doi request reprint Pediatric status asthmaticus
    Christopher L Carroll
    Division of Pediatric Critical Care, Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, CT 06106, USA
    Crit Care Clin 29:153-66. 2013
    ..In this article the pathophysiology and treatment of status asthmaticus is discussed, and the literature regarding second-line treatments is critically assessed to apply an evidence basis to the treatment of this severe disease...
  2. doi request reprint Pulmonary mechanics following albuterol therapy in mechanically ventilated infants with bronchiolitis
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    J Asthma 49:688-96. 2012
    ..The purpose of this study was to describe the physiologic response to these medications in infants intubated and mechanically ventilated for bronchiolitis...
  3. doi request reprint β2-adrenergic receptor haplotype linked to intubation and mechanical ventilation in children with asthma
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, CT 06106, USA
    J Asthma 49:563-8. 2012
    ..However, this has not previously been assessed in this population. We hypothesized that genetic polymorphisms of the β(2)-adrenergic receptor (ADRβ(2)) are associated with intubation and mechanical ventilation in children with asthma...
  4. doi request reprint Beta-adrenergic receptor polymorphisms associated with length of ICU stay in pediatric status asthmaticus
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, Connecticut 06106, USA
    Pediatr Pulmonol 47:233-9. 2012
    ..Our hypothesis was that genotypic differences are associated with magnitude of response to ADRβ(2) agonist treatment during severe asthma exacerbations in children...
  5. doi request reprint Use of dexmedetomidine for sedation of children hospitalized in the intensive care unit
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    J Hosp Med 3:142-7. 2008
    ..Dexmedetomidine is a potentially useful sedative for hospitalized children, but there is little published data regarding its safety, dosage, or efficacy...
  6. doi request reprint Slow-responders to IV beta2-adrenergic agonist therapy: defining a novel phenotype in pediatric asthma
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Pediatr Pulmonol 43:627-33. 2008
    ..Our hypothesis is that children who respond more slowly to IV beta(2)-AR agonist therapy comprise a distinct phenotype...
  7. doi request reprint Beta2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations
    Christopher L Carroll
    Department of Pediatrics, Division of Pediatric Critical Care, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    Chest 135:1186-92. 2009
    ..Our hypothesis is that genotypic differences contribute to patient response to beta(2)-AR agonist treatment during severe asthma exacerbations in children...
  8. ncbi request reprint Emergent endotracheal intubations in children: be careful if it's late when you intubate
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT, USA
    Pediatr Crit Care Med 11:343-8. 2010
    ..The purpose of this study was to delineate the risks of emergent endotracheal intubations in children...
  9. doi request reprint Identifying an at-risk population of children with recurrent near-fatal asthma exacerbations
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    J Asthma 47:460-4. 2010
    ..The purpose of this study was to examine the factors related to recurrent ICU admissions in children with asthma...
  10. ncbi request reprint Childhood overweight increases hospital admission rates for asthma
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington St, Hartford, CT 06106, USA
    Pediatrics 120:734-40. 2007
    ..We hypothesized that overweight children who presented to the emergency department with asthma exacerbations were more likely to be admitted to the hospital than nonoverweight children...
  11. ncbi request reprint The increased cost of complications in children with status asthmaticus
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Pediatr Pulmonol 42:914-9. 2007
    ..This suggests that intubation and mechanical ventilation itself may increase the risk of developing a complication in this population...
  12. ncbi request reprint A modified pulmonary index score with predictive value for pediatric asthma exacerbations
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Ann Allergy Asthma Immunol 94:355-9. 2005
    ..Several clinical asthma scores have been derived from combinations of physical findings in pediatric asthmatic patients...
  13. ncbi request reprint Protocol-based titration of intravenous terbutaline decreases length of stay in pediatric status asthmaticus
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Pediatr Pulmonol 41:350-6. 2006
    ..3 vs. 8.3 +/- 2.7 days, P < 0.01), and reduced hospital charges ($19,298 +/- $10,516 vs. $26,528 +/- $12,328, P = 0.04). The method of administration of IV terbutaline significantly influenced ICU length of stay and hospital charges...
  14. doi request reprint Severe exacerbations in children with mild asthma: characterizing a pediatric phenotype
    Christopher L Carroll
    Department of Pediatrics, Division of Pediatric CriticalCare, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    J Asthma 45:513-7. 2008
    ..Our objective was to describe a population of children with mild asthma admitted to the ICU with severe exacerbations...
  15. ncbi request reprint Noninvasive positive pressure ventilation for the treatment of status asthmaticus in children
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut 06106, USA
    Ann Allergy Asthma Immunol 96:454-9. 2006
    ..Although this technique has some benefits in the treatment of status asthmaticus in adults, the use of NPPV in pediatric patients with asthma has not been described...
  16. ncbi request reprint Chronic inhaled corticosteroids do not affect the course of acute severe asthma exacerbations in children
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut06106, USA
    Pediatr Pulmonol 41:1213-7. 2006
    ..Although useful as a preventive therapy, the chronic use of ICS does not appear to affect the course of severe acute asthma exacerbations in pediatric patients once hospitalized...
  17. doi request reprint Barotrauma not related to type of positive pressure ventilation during severe asthma exacerbations in children
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, Connecticut, USA
    J Asthma 45:421-4. 2008
    ..However, the comparative risk of barotrauma associated with the use of NPPV has not been evaluated in this population...
  18. doi request reprint Factors associated with the development of severe asthma exacerbations in children
    Kathleen A Sala
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    J Asthma 48:558-64. 2011
    ..Despite the prevalence of this disease in children, the factors associated with the development of these severe exacerbations are largely unknown...
  19. ncbi request reprint Endotracheal intubation and pediatric status asthmaticus: site of original care affects treatment
    Christopher L Carroll
    Pediatric Critical Care, Connecticut Children s Medical Center, Hartford, CT, USA
    Pediatr Crit Care Med 8:91-5. 2007
    ..Our hypothesis was that children who sought care at community hospitals received less aggressive treatment and more frequent intubation than children who sought care at a children's hospital...
  20. doi request reprint Advances in treating acute asthma exacerbations in children
    Craig M Schramm
    Pulmonary Division, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    Curr Opin Pediatr 21:326-32. 2009
    ....
  21. ncbi request reprint Childhood obesity increases duration of therapy during severe asthma exacerbations
    Christopher L Carroll
    Department of Pediatrics, Connecticut Children s Medical Center, Hartford, CT, USA
    Pediatr Crit Care Med 7:527-31. 2006
    ..We hypothesized that obesity is associated with the need for increased duration of therapy in children admitted to the ICU with status asthmaticus...
  22. doi request reprint Corticosteroid therapy in critically ill pediatric asthmatic patients
    John S Giuliano
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Pediatr Crit Care Med 14:467-70. 2013
    ..However, no specific dosing recommendations have been made for children admitted to the PICU. We aim to determine current asthma corticosteroid dosing preferences in PICUs within North America...
  23. pmc Duration of red blood cell storage is associated with increased incidence of deep vein thrombosis and in hospital mortality in patients with traumatic injuries
    Philip C Spinella
    Department of Pediatrics, Connecticut Children s Medical Center, 282 Washington Street, Hartford, CT 06106, USA
    Crit Care 13:R151. 2009
    ..To determine if duration of RBC storage is associated with adverse outcomes we studied critically ill trauma patients requiring transfusion...
  24. doi request reprint Survey of transfusion policies at US and Canadian children's hospitals in 2008 and 2009
    Philip C Spinella
    Department of Pediatrics, Connecticut Children s Hospital, Hartford, Connecticut, USA
    Transfusion 50:2328-35. 2010
    ..Our objective was to determine the current transfusion policies in US and Canadian children's hospitals for both neonatal and pediatric general populations...
  25. doi request reprint Use of a massive transfusion protocol with hemostatic resuscitation for severe intraoperative bleeding in a child
    Alex M Dressler
    Department of Critical Care, Connecticut Children s Medical Center, Hartford, CT 06106, USA
    J Pediatr Surg 45:1530-3. 2010
    ..The MT protocol principles, benefits, and postoperative course of the patient are described...
  26. doi request reprint Pediatric code events: does in-house intensivist coverage improve outcomes?*
    Christopher L Carroll
    Division of Pediatric Critical Care, Connecticut Children s Medical Center, Hartford, CT
    Pediatr Crit Care Med 15:250-7. 2014
    ..Our aim was to determine whether in-house attending coverage influenced the prevalence and outcomes of pediatric code events...
  27. ncbi request reprint Inhaled prostacyclin following surgical repair of congenital heart disease--a pilot study
    Christopher L Carroll
    Department of Pediatrics, Children s Memorial Hospital and Northwestern University School of Medicine, Chicago, Illinois 60614, USA
    J Card Surg 20:436-9. 2005
    ..In this prospective interventional pilot study, we examined the physiologic effects of inhaled PGI2 in children with congenital heart disease and pulmonary hypertension...
  28. ncbi request reprint Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide
    Lisa K Kelly
    Department of Pediatrics, Children s Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60614, USA
    J Pediatr 141:830-2. 2002
    ..The condition of one infant subsequently deteriorated, and alveolar capillary dysplasia was found at autopsy. The surviving infants were discharged with normal oxygen saturations in room air...
  29. ncbi request reprint Endotracheal albuterol treatment of acute bronchospasm
    Christopher L Carroll
    Am J Emerg Med 22:506-7. 2004