Research Topics
| Yalin WuSummaryAffiliation: Columbia University Country: USA Publications
| Collaborators |
Detail Information
Publications
Structural characterization and DPPH radical scavenging activity of an arabinoglucogalactan from Panax notoginseng rootYalin Wu
Department of Chemistry, Columbia University, New York, New York 10027, USA
J Nat Prod 71:241-5. 2008..Additionally, 1 exhibited high scavenging activity against DPPH free radicals with a 50% scavenging concentration (SC50) of 11.72 +/- 0.91 microg/mL, suggesting that this arabinoglucogalactan is a potential antiradical...
A new class of natural glycopeptides with sugar moiety-dependent antioxidant activities derived from Ganoderma lucidum fruiting bodiesYalin Wu
Department of Ophthalmology, Columbia University, New York, New York 10032, USA
J Proteome Res 8:436-42. 2009....
Fundus autofluorescence and the bisretinoids of retinaJanet R Sparrow
Department of Ophthalmology, Columbia University, 630 W 168th Street, New York, NY 10032, USA
Photochem Photobiol Sci 9:1480-9. 2010..However, two retinoids of the visual cycle, all-trans-retinyl ester and all-trans-retinal, did not exhibit fluorescence at 488 nm excitation...
Phospholipid meets all-trans-retinal: the making of RPE bisretinoidsJanet R Sparrow
Department of Ophthalmology, Columbia University, New York, NY 10032, USA
J Lipid Res 51:247-61. 2010..The propensity of these compounds to negatively impact on the cells has been linked to the pathogenesis of some retinal disorders including juvenile onset recessive Stargardt disease and age-related macular degeneration...
Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt diseaseYalin Wu
Department of Ophthalmology, Columbia University, New York, New York 10032, USA
J Biol Chem 284:20155-66. 2009..Efforts to clarify the composition of RPE lipofuscin are important because these compounds are targets of gene-based and drug therapies that aim to alleviate ABCA4-related retinal disease...
Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degenerationYalin Wu
Department of Ophthalmology, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Proc Natl Acad Sci U S A 107:7275-80. 2010..Whereas various processes play a role in drusen formation, these findings are indicative of a contribution from lipofuscin photooxidation in RPE...
Experimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epitheliumJanet R Sparrow
Departments of Ophthalmology and Pathology and Cell Biology, Columbia University, New York, NY 10032, USA
Methods Mol Biol 652:315-27. 2010..This approach allows for a population of RPE cells that have accumulated the lipofuscin fluorophore A2E in addition to A2E-free cells...
Isolation and characterization of a mannoglucan from edible Cordyceps sinensis myceliumYalin Wu
Department of Chemistry, Zhejiang University, Hangzhou 310027, People s Republic of China
Carbohydr Res 342:870-5. 2007..Compound 1 showed weak cytotoxicity activity against SPC-I (IC(50)=63 microg/mL) cancer line, and no obvious cytotoxicity activities against BCAP37 (IC(50)>100 microg/mL) and SW480 (IC(50)>100 microg/mL) cancer lines...
Structural analysis of an alkali-extractable polysaccharide from the seeds of Retama raetamssp. gussoneiYalin Wu
Department of Chemistry, Zhejiang University, Hangzhou, 310027, People's Republic of China
J Nat Prod 69:1109-12. 2006..This is the first report on the isolation of an alkali-extractable polysaccharide from this plant...
Structural analysis of a neutral (1-->3),(1-->4)-beta-D-glucan from the mycelia of Cordyceps sinensisYalin Wu
Department of Chemistry, Zhejiang University, Hangzhou, 310027, People's Republic of China
J Nat Prod 68:812-4. 2005..NMR and IR spectroscopic measurements showed that the sugar residues were beta-glycosidically linked...
